• The Korean Journal of Nuclear Medicine
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• v.14 no.2
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• pp.61-66
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• 1980

We studied four patients with muscle necrosis associated with acute renal failure to evaluate the diagnostic value of the bone scan in this disease. The illness followed carbon monoxide poisoning in two patients, acute physical exertion in one and contaminated intramuscular injection in the other. Whole-body rectilinear bone scans using technetium 99m-methyldiphosphonate were done. In all patients, increased muscle labelling at the regions of suspected muscle injury was showed, and in one, it was after normalization of serum muscle enzyme levels. In one patient, the bone scan was rechecked 8 months later and showed no residual abnormality. Above all, the site and precise extent of muscle injury could be detected and the degree of muscle labelling seemed to correlate with the severy of muscle injury. These findings suggest that isotope scanning may be useful in the diagnosis of patients with acute muscle necrosis.

• The Journal of Korean Medicine
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• v.30 no.3
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• pp.106-110
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• 2009

Objective : To study the Oriental Medicine-based strategies or therapeutics for chronic HBV infection. Methods : A chronic HBV carrier was treated with only oriental therapies. Then, serum biochemical parameters were serially chased, and change of HBV-DNA level was evaluated. Result : The biochemical indicators (AST, ALT, gamma-GTP, bilirubin) fluctuated during the treatment period. After one episode of drastic elevation of serum aminotransferase, HBV-DNA disappeared from the blood along with normalization of biochemical parameters within two years of beginning treatment. Conclusion : Oriental Medicine-based therapeutics could be an alternative strategy against chronic infection of HBV.

• Journal of the Korea Society of Computer and Information
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• v.7 no.2
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• pp.73-78
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• 2002

Recognition system of noise processing technique. A method combining SNR normalization with RAS is considered as a noise Processing and the performance of the speech recognition system can be improved using other noise processing technique. Experiment of recognition system is the internal organs that using a general digital signal processor(TMS320C31). Recognition word set is composed of 60 command words for of Rce environment and order of computer. Simulation is considered as a colored noise of general environment. The results of experiment showed that the recognition word set gives 94.61% of efficiency of recognition at maximum in case of the combination of SNR normalization and spectral subtraction.

• Proceedings of the ESK Conference
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• 1996.10a
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• pp.21-25
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• 1996

The Electomyographic (EMG) signals of flexor-extensor muscle pairs were investigated to identify the neural excitation pattern of low-back pain (LBP) patients during a repetitive bending motion. New parameters and EMG normalization technique were developed to quantitatively represent the difference of temporal EMG patterns between ten healthy subjects and ten LBP patients. Flexor-extensor muscle pairs such as rectus abdominis(RA)-erector spinae (ES at LS), external oblique(EO)-internal oblique(IO), rectus femois (quadriceps: QUD)-biceps femoris(hamstrings:HAM), and tibialis anterior(TA)-gastrocnemius(GAS) pairs of muscles were selected in this study. Results indicated that the temporal EMG pattern such as the peak timing difference of QUD-HAM muscle pair and the duration of coexcitation of ES-RA muscle pair showed a statistically isgnificant difference between healthy subjects and LBP patients. These results indicated that the new technique and parameters could be used as a diagnostic tool especially for LBP patients with soft tissue injuries that are rarely dentified by traditional imaging techniques such as X-ray, CT scan or MRI. Improtantly, the new EMG technique did not require the maximal volutary contraction(MVC) measure for normalization that helped patients minimize the pain experience during and after the session. Further study needs to be made to validate and refine this method for clinical application.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.8C
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• pp.529-535
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• 2011

After permission for utilization of TV white space by FCC, a lot of attentions are focused on spectrum sensing, and various spectrum sensing methods have been proposed. However, they do not consider real environment, thus they are hard to achieve the required performance. In this paper, we propose resolutions for the problem which could be occurred in implementation of spectrum sensing module and verify performance of the proposed methods with computer simulation. The first proposed method utilizes channel status information to separate received signal and spurious for reducing false alarm probability caused by system internal spurious. The another proposed scheme is subband normalization method to prevent miss detection caused by multiple narrow band signals with different received signal strength. The simulation results verify that we can prevent false alarm cause by spurious components with the proposed system internal spurious cognition. Moreover, the proposed subband normalization method shows that it could overcome performance degradation caused by received signal strength difference.

• Journal of Korean Neurosurgical Society
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• v.40 no.1
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• pp.28-30
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• 2006

Two patients presented with amaurosis fugax[AMF]. despite treatment with antiplatelet drugs and anticoagulants due to previous transient ischemic attacks. Angiography demonstrated severe stenosis in the cavernous and petrous internal carotid artery[ICA] respectively, with reduced flow in the ophthalmic artery[OA]. Endovascular stent placement in both patients resulted in normalization of the vessel lumen of the stenotic vessel segments. In addition, complete restoration of OA flow was noted immediately after stenting. Both patients showed no further episode of AMF over a follow-up period of 38 and 23 months respectively. Our clinical and angiographic findings suggest that hemodynamic Insufficiency in retinal vasculature caused by a stenosis of the cavernous or petrous ICA can be treated successfully by endovascular stent.

• Biomedical Science Letters
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• v.29 no.4
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• pp.220-230
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• 2023

Identification of the pathogens causing infection is important in terms of patient's health management and infection control. Synovial fluids could be used as clinical samples to detect causative pathogens of prosthetic joint infections (PJIs) using molecular diagnostic assays, therefore, normalization and validation of clinical samples are necessary. Microbial culture is considered the gold standard for all infections, including PJIs. Recently, molecular diagnostic methods have been developed to overcome the limitation of microbial culture. Therefore, guideline for validating clinical samples to provide reliable results of molecular diagnostic assays for infectious diseases is required in clinical field. The present study aimed to develop an accurate validating method of synovial fluid clinical samples using GAPDH gene as an internal control to perform the quantitative PCR TaqMan probe assay to detect pathogens causing PJIs.

• The Journal of Internal Korean Medicine
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• v.44 no.2
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• pp.277-284
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• 2023

Objective: This study investigated the effects of Guibiondam-tang-gamibang on patients in the thyrotoxic phase of painless thyroiditis. Methods: A patient in the thyrotoxic phase of painless thyroiditis was treated with Guibiondam-tang-gamibang combined with Western medicine (i.e., beta blockers). The effect of treatment was evaluated according to the pulse rate, NRS, the frequency of subjective symptoms, and sleep time. In addition, the thyroid function was evaluated with TSH, Free T4, and T3 using blood tests. Results: After treatment, the pulse rate decreased, and the NRS and frequency of subjective symptoms disappeared after improvement. Sleep time increased. In the thyroid function test, a significant normalization of each value was observed. Conclusion: This study suggests that Guibiondam-tang-gamibang can be effectively treated in patients with painless thyroiditis in the thyrotoxic phase. However, further studies should be conducted.

• Journal of Veterinary Clinics
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• v.41 no.3
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• pp.150-156
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• 2024

This retrospective case series assessed the effectiveness of commercially available oral fecal microbiota transplantation (FMT) for treating chronic enteropathies in eight animals, five dogs, and three cats, between 2020 and 2023 at the Seoul National University Veterinary Medical Teaching Hospital. Chronic enteropathies, often resistant to conventional therapies, present a significant challenge in veterinary medicine. To assess oral capsule FMT's effectiveness (Doggybiome^® one capsule daily for dogs and Kittybiome^® one capsule daily for cats) as a universal adjunctive therapy for chronic enteropathies across species not responding to traditional treatments. This retrospective case series applied a uniform evaluation of gastrointestinal symptoms and treatment efficacy, utilizing established scoring systems (Canine Inflammatory Bowel Disease Activity Index [CIBDAI] and Canine Chronic Enteropathy Clinical Activity Index [CCECAI] for dogs, Feline Chronic Enteropathy Activity Index [FCEAI] for cats) before and one month after FMT. This approach ensured consistency in hypothesis testing across the study population. Results revealed significant improvements in clinical indices post-FMT, with notable reductions in the CIBDAI, CCECAI, and FCEAI scores (p < 0.05). Additionally, symptoms such as anorexia, lethargy, diarrhea, vomiting, and weight loss showed marked improvement, with normalization of appetite and activity levels observed in most cases. No adverse effects were reported, indicating the safety and tolerability of this treatment. This study highlights the potential of oral capsule FMT as a viable therapeutic option for dogs and cats with chronic enteropathies unresponsive to conventional treatments, providing a new avenue for clinical management. Further research is warranted to expand these findings and explore the microbiome changes associated with FMT in veterinary patients.

• Proceedings of the Korean Geotechical Society Conference
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• 2000.03b
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• pp.239-246
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• 2000

It has been generally much fine contents in West Coast of Korea. When cyclic shear stress causing liquefaction was estimated as using cyclic triaxial tests in these grounds, it didn't appear linear relations between deviator stress and confining stress where σ'₃ was more than 150 kpa. Namely, due to no normalization of cyclic shear stress ratio, the errors of this is increased. Therefore, more confining stress is increased, more increment of deviator stress is decreased. So, using linear relations between tanø'/sub d/ of dynamic internal friction angle and CSR where σ'₃ was less than 150 kpa, liquefaction of these grounds was evaluated. Also, as doing detail evaluation which had carried response analysis of earthquake, this appeared good results which was well compatible with empirical methods using N-value of SPT. It was thought that these result evaluated vulnerable liquefaction area more correct than existing methods. Also, characteristics of liquefaction in West Coast grounds was compared with clean sands, with analysis of behavior of pore pressure ratio and axial strain affected by fine contents, as cyclic loading was applied.