• 대한한방내과학회지
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• 제27권4호
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• pp.888-894
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• 2006

Objectives : For the purpose of developing new anti-HIV agents from natural sources, the extracts of Ricinus communis were tested for their inhibitory effects on essential enzymes reverse transcriptase (RT), protease and alpha-glucosidase. Inhibition activity of major compounds of Ricinus communis were predicted from quantitative structure activity relationships (QSAR) in silico. Methods and Results : In the anti-HIV-1 RT using enzyme-linked oligonucleotide sorbent assay (ELOSA) method, water and methanol extracts (100ug/ml) of Ricinus communis showed strong activity of 94.2% and 82.7%, respectively. In the HIV-1 protease and alpha-glucosidase inhibition assay, neither water nor methanol extracts of Ricinus communis inhibited the activity of the enzyme to cleave any substrates as oligopeptides and oligosaccharides. Conclusions : We found that for these samples it is possible that the inhibition of the RT in vitro is due to the secondary metabolites of Ricinus communis such as ricinine and quercetin. It would beof great interest to identify the compounds which are responsible for this inhibition, since all therapeutically useful agents up to date are RT inhibitors.

• 대한기계학회논문집
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• 제16권9호
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• pp.1654-1668
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• 1992

본 연구에서는 경험적으로 측정점 사이의 간격과 구경의 크기를 정하는 방법 에 대하여 살펴보았다.이에 반하여 둘러싸기 오차(wraparound error)는 이산화된 파수 성분 데이타의 처리 과정에서 발생하게 되는데, 이를 줄이기 위한 방법의 일환으 로 본 논문에서는 제로패딩(zero padding)방법을 도입하였다. 또한 둘러싸기 오차 (wraparound error)의 크기를 정량화하여 신뢰할 수 있는 예측결과의 범위를 살펴보았 다.

• 한국정밀공학회지
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• 제20권12호
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• pp.25-33
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• 2003

A burr has been defined as undesirable projection of material formed as a result of plastic flow from a cutting or shearing operation. It is unavoidable in all kinds of machining operation. As a result, burr makes troubles on manufacturing process due to deburring cost, quality of products and productivity. In this study, the primary interest is about exit burr. The burr formation mechanism in each type of burr is classified. Data bases are developed to predict burr formation result. In the milling operation, we develop an algorithm to analyze the burr formation mechanism by the geometrical analysis on the multi featured workpiece with multi cutting path. The algorithm includes three steps, i. e., the feature identification, the cutting condition identification, and the analysis on exit burr formation. We can predict which portion of workpiece would have the exit burr in advance so that we can manage to find a way to minimize the exit burr formation in an actual cutting. Also, this algorithm can be implemented in a commercial CAM package so that we can simulate the NC code to review the burr formation in advance.

• 응용통계연구
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• 제29권1호
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• pp.257-266
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• 2016

비선형 모형인 확률계수 자기회귀 모형의 모수를 추정하기 위해 전체 데이터를 부표본으로 나누어 확률계수 ${\phi}(t)$가 초기값, ${\phi}(0)$를 갖는 특별한 경우를 제안하고 추정하였다. 모의 실험으로 부표본으로 나누어 확률계수 자기회귀 모형을 추정하는 더 바람직함을 확인하였다. 실증분석에서는 한국 Mumps 자료를 선형 모형인 자기회귀 모형과 확률 계수 자기회귀 모형에 각각 적합시켜 모수를 추정하고, PRESS 값을 비교하여 확률계수 자기회귀 모형의 예측이 더 우수함을 보였다.

• 방송공학회논문지
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• 제22권1호
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• pp.136-139
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• 2017

최근 VR(virtual reality)의 관심이 급격하게 늘어감에 따라 HMD(Head Mounted Display), 360도 VR 카메라 등 많은 VR기기들이 출시되고 있다. 그럼에도 불구하고 현재 360도 VR 비디오의 경우 기존의 일반 2D 비디오의 코덱을 그대로 사용하고 있다. 기존의 코덱은 360도 VR 비디오의 특징을 고려하지 않고 비디오를 부/복호화하기 때문에 압축효율이 떨어지게 된다. 본 논문에서는 360도 VR 비디오의 특성 중 시점이 달라 생기는 왜곡을 보정한 참조프레임으로 사용함으로써 압축효율을 높이는 방법을 제안한다. 제안한 방법을 적용할 경우 시간적 예측 효율이 높아져 압축효율이 높아진다.

• Coupled systems mechanics
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• 제4권1호
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• pp.67-98
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• 2015

Numerical prediction of dynamic behavior of fully coupled saturated porous media is of great importance in many engineering problems. Specifically, static and dynamic response of soils - porous media with pores filled with fluid, such as air, water, etc. - can only be modeled properly using fully coupled approaches. Modeling and simulation of static and dynamic behavior of soils require significant Verification and Validation (V&V) procedures in order to build credibility and increase confidence in numerical results. By definition, Verification is essentially a mathematics issue and it provides evidence that the model is solved correctly, while Validation, being a physics issue, provides evidence that the right model is solved. This paper focuses on Verification procedure for fully coupled modeling and simulation of porous media. Therefore, a complete Solution Verification suite has been developed consisting of analytical solutions for both static and dynamic problems of porous media, in time domain. Verification for fully coupled modeling and simulation of porous media has been performed through comparison of the numerical solutions with the analytical ones. Modeling and simulation is based on the so called, u-p-U formulation. Of particular interest are numerical dispersion effects which determine the level of numerical accuracy. These effects are investigated in detail, in an effort to suggest a compromise between numerical error and computational cost.

• 서비스연구
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• 제2권2호
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• pp.35-43
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• 2012

데이터 마이닝은 특정분야에서만 관심을 갖는 분야가 아니라 현재 우리주변 여러 분야에서 많이 사용되고 응용되고 있다. 즉, 수많은 데이터 가운데 숨겨져 있는 유용한 상관관계를 발견하여, 미래에 실행 가능한 정보를 예측하여 추출해 내고 추후에 의사 결정에 이용하는 과정을 말한다. 하지만, 일부 데이터 집합에서는 매우 많은 결측치를 포함하는 변수들이 존재한다. 다시 말해서 다수의 레코드에서 측정치가 존재하지 않는 데이터 집합이 존재한다. 그래서 본 논문에서는 Cholesterol 값을 예측하기 위한 결측치 처리에 따른 모델트리 알고리즘을 적용하고, 실험을 통해서 각 처리방식에 대한 성능을 분석한다. 또는 이 결과를 통하여 결측치 대체방법에 대한 효율적인 적용사례를 제시한다.

• 한국컴퓨터정보학회논문지
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• 제11권1호
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• pp.293-300
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• 2006

추천 시스템은 사용자들에게 관심 품목을 찾거나 평가하는데 도움을 준다. 이런 시스템은 전자 상거래를 비롯하여 전자 도서관 같은 여러 영역에서 강력한 도구가 되었다. 소비자의 인구통계학적 및 과거 구매 행동에 대한 분석을 바탕으로 미래의 구매 행동을 예측하여 판매자가 고객에게 상품을 추천할 수 있다. 본 논문에서는 고객의 패턴이나 성향에 가장 적절한 상품을 탐색하여 고객의 만족도를 높여줄 수 있는 개인화 추천시스템의 설계 및 개발에 관하여 기술한다. 제안된 시스템은 데이터 마이닝의 연관규칙을 적용하여 고객의 구매를 예측할 수 있는 실시간 분석서비스를 제공할 수 있다.

• 소성∙가공
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• 제19권6호
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• pp.378-386
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• 2010

Nowadays there has been great interest in using heat treated cast material for press dies due to several advantages like reduction in die production costs. However, in hot press forming processes H13 forged tool steel is mostly used. Cooling performance of dies in hot press forming processes is considered as an important factor of study and also the IHTC parameter between cast material die and sheet metal should be considered as an essential. In the present study, the IHTC was calculated for the sheet metal in the hot press forming process with cast and forged material dies. The temperature measurements were performed for the sheet metal, casting and forged material dies by applying various contact pressure in hot press forming. IHTC was calculated and studied by adopting the inverse heat convection method in DEFORM-2D. Each IHTC was considered as a function of contact time and contact pressure. The experimental data were compared with calculated data obtained from the proposed equation and references.

• Environmental Engineering Research
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• 제25권3호
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• pp.281-289
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• 2020

Environmental fate of ionizable organic pollutants such as perfluoroalkyl acids (PFAAs) are of increasing interest but has not been well understood because of uncertain values for parameters related with atmospheric interphase partitioning behavior. In the present study, not only the values for air-water partition coefficient (K_AW) and dissociation constant (pKa) of PFAAs were induced by adjusting to in situ measurements of air-water distribution coefficient between vapor phase and rainwater but also gas-particle partition coefficients were also estimated using three-phase partitioning model of ionizable organic pollutants, in situ measurements of PFAAs in aerosol and air vapor phase, and obtained parameter values. The pKa values of PFAAs we obtained were close to the minimum values suggested in literature except for perfluorooctane sulfonic acids, and COSMOtherm-modeled K_AW values were assessed to more appropriate among suggested values. When applying parameter values we obtained, it was predicted that air particle-associated fate and transport of PFAAs could be negligible and PFAAs could distribute ubiquitously along the transection from urban to rural region by pH-dependent phase transfer in air. Our study is expected to have some implications in prediction of the environmental redistribution of other ionizable organic compounds.