• Journal of Life Science
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• v.26 no.8
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• pp.904-910
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• 2016

Complex traits are determined by the combined effects of many loci and are affected by gene networks or biological pathways. Systems biology approaches have an important role in the identification of candidate genes related to complex diseases or traits at the system level. The gene network analysis has been performed by diverse types of methods such as gene co-expression, gene regulatory relationships, protein-protein interaction (PPI) and genetic networks. Moreover, the network-based methods were described for predicting gene functions such as graph theoretic method, neighborhood counting based methods and weighted function. However, there are a limited number of researches in livestock. The present study systemically analyzed genes associated with 102 types of economic traits based on the Animal Trait Ontology (ATO) and identified their relationships based on the gene co-expression network and PPI network in cattle. Then, we constructed the two types of gene network databases and network visualization system (http://www.nabc.go.kr/cg). We used a gene co-expression network analysis from the bovine expression value of bovine genes to generate gene co-expression network. PPI network was constructed from Human protein reference database based on the orthologous relationship between human and cattle. Finally, candidate genes and their network relationships were identified in each trait. They were typologically centered with large degree and betweenness centrality (BC) value in the gene network. The ontle program was applied to generate the database and to visualize the gene network results. This information would serve as valuable resources for exploiting genomic functions that influence economically and agriculturally important traits in cattle.

• The Korean Journal of Ecology
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• v.26 no.3
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• pp.143-150
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• 2003

Korea has plentiful precipitation but rainfall events concentrate on several months of rainy season in her weather condition. Korea, therefore, experiences drought for a given period every year. Moreover the soil has usually low water holding capacity, as it is composed coarse particles originated from the granite. Response of several oaks and the Korean red pine (Pinus densiflora) on water stress showed that water budget was significant factor determining vegetation distribution. In addition, dehydration level due to cold resistance mechanism of several evergreen plants during the winter season was closely related to their distribution in natural condition. Experimental result under water stress showed that the Korean red pine was very tolerant to desiccation but the seedlings showed high mortality during the dry season. The mortality tended to proportionate to soil moisture content of each site. A comparison between soil moisture content during June when it is severe dry season and moisture content of the culture soil when the pine seedlings reached the permanent wilting point due to water withheld proved that high mortality during the dry season was due to water deficit. Water potential of sample plants measured during the exposure experiment to the air pollutant showed a probability that water related factors would dominate the occurrence of visible damage and the tolerance level of sample plants. In both field survey and laboratory experiment, plants exposed to air pollution showed more rapid transpiration than those grown in the unpolluted condition. The result would due to injury of leaf surface by air pollutants. Aluminum (Al/sup 3+/) increased in the acid soil not only inhibits root growth but also leads to abnormal distribution of root system and thereby caused water stress. The water stresses due to air pollution and soil acidification showed a possibility that they play dominating roles in inducing forest decline additionally to the existing water deficit due to weather and soil conditions in Korea. Sludge, which can contribute to improve field capacity, as it is almost composed of organic matter, showed an effect ameliorating the retarded growth of plant in the acidified soil. The effect was not less than that of dolomite known in widely as such a soil ameliorator. Litter extract contributed also to mitigate the water stress due to toxic Al/sup 3+/. We prepared a model showing the potential interaction of multiple stresses, which can cause forest decline in Korea by synthesizing those results. Furthermore, we suggested restoration plans, which can mitigate such forest decline in terms of soil amelioration and vegetation restoration.

• Journal of Korean Society of Forest Science
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• v.106 no.1
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• pp.40-53
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• 2017

The purpose of this study was to evaluate the effects of container types on physiological characteristics of Zelkova serrata, Fraxinus rhynchophylla and Quercus serrata in the container nursery stage. We used 16 container types [4 growing densities (100, 144, 196 and $256\;seedlings/m^2$)${\times}4$ cavity volumes (460, 380, 300 and $220cm^3/cavity$)] and performed two-way ANOVA to test the differences in photosynthesis, photochemical efficiency and chlorophyll content among container types. Also, multiple regression analysis was conducted to correlate container dimensions with photosynthetic rate. Container types had a strong influence on photosynthesis of three species seedlings. Growing densities and cavity volumes had a significant interaction effect on photosynthetic rate, water use efficiency, stomatal conductance and chlorophyll contents except stomatal conductance of Q. serrata. In all three species, however, interactions between the two factors of container type were not found with regard to photochemical efficiency. Growing density was negatively correlated with photosynthetic rate of F rhynchophylla and Q. serrata, while cavity volumes positively affected on those of three species seedlings. The range of optimal container types was determined by multiple regression analysis based on photosynthetic rate. Consequently, optimal growing density and cavity volume of container by each tree species were found to be approximately $160{\sim}210\;seedlings/m^2$ and $430{\sim}460cm^3/cavity$ for Z. serrata, $130{\sim}150\;seedlings/m^2$ and $390{\sim}440cm^3/cavity$ for F. rhynchophylla and $130{\sim}170\;seedlings/m2$ and $420{\sim}460cm^3/cavity$ for Q. serrata, respectively. Application of adequate container will induce higher quality seedling production in nursery stage, which will also increase seedling growth in plantation stage.

• Economic and Environmental Geology
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• v.50 no.3
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• pp.215-224
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• 2017

Arsenic (As) is known to be the most toxic element and frequently detected in groundwater environment. Inorganic As exists as arsenite [As(III)] and arsenate [As(V)] in reduced and oxidized environments, respectively. It has been reported that the toxicity of arsenite is much higher than that of arsenate and furthermore arsenite shows relatively higher mobility in aqueous environments. For this reason, there have been numerous researches on the process for oxidation of arsenite to arsenate to reduce the toxicity of arsenic. In particular, photooxidation has been considered to be simple, economical, and efficient to attain such goal. This study was conducted to evaluate the applicability of naturally-occurring goethite as a photocatalyst to substitute for $TiO_2$ which has been mostly used in the photooxidation processes so far. In addition, the effects of several factors on the overall performance of arsenite photocatalytic oxidation process were evaluated. The results show that the efficiency of the process was affected by total concentration of dissolved cations rather than by the kind of those cations and also the relatively higher pH conditions seemed to be more favorable to the process. In the case of coexistence of arsenite and arsenate, the removal tendency by adsorption onto goethite appeared to be different between arsenite and arsenate due to their different affinities with goethite, but any effect on the photocatalytic oxidation of arsenite was not observed. In terms of effect of humic acid on the process, it is likely that the higher concentration of humic acid reduced the overall performance of the arsenite photocatalytic oxidation as a result of competing interaction of activated oxygen species, such as hydroxyl and superoxide radicals, with arsenite and humic acid. In addition, it is revealed that the injection of oxygen gas improved the process because oxygen contributes to arsenite oxidation as an electron acceptor. Based on the results of the study, consequently, the photocatalytic oxidation of aqueous arsenite using goethite seems to be greatly feasible with the optimization of process.

• Journal of Nutrition and Health
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• v.50 no.1
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• pp.32-40
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• 2017

Purpose: Obesogenic environments in children, in particular excessive intake of sodium, generate hypertension, which is a major risk factor for chronic diseases. Methods: In all, 725 children, 379 boys and 373 girls, aged 8~9 years were recruited from seven elementary schools in Kuro-ku, Seoul. To evaluate whether or not obesity risk was modulated by salt-sensitive genes, Solute Carrier Familiy 12 member 3 (SLC12A3) was used as the target. After children were assigned into obese (BMI > 85 percentile) or non-obese groups, anthropometry, blood biochemistry, and dietary intakes were measured according to the genotypes GG (wild) or GA+AA (hetero+mutant). Results: Without gender differences, high TG and low HDLc were detected in the obese group compared to the non-obese group. Regardless of obesity, weight gain and blood pressure (BP) increased in the SLC12A3 GA+AA genotype rather than in the GG type. HDLc was associated with obesity risk without genotype difference. Odd ratios for risk of obesity were 15.57 (95% CI 2.192~110.654), 22.84 (95% CI 1.565~333.469), and 9.32 (95%CI 1.262~68.817) in boys and girls with GA+AA genotypes as sodium intake increased above 4,000 mg/day. Dietary calcium, sodium, folate, and vit C were associated with obesity risk according to gender or genotype differences. Since high folate intake reduced obesity risk in only boys with GG type. Risk for overweight and obesity increased in boys with GA+AA genotypes and dietary habits with high sodium and cholesterol and low folate. Conclusion: The A allele of SLC12A3 rs11643718 was sensitive to development of obesity in children as sodium intake increased.

• Korean Journal of Weed Science
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• v.12 no.2
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• pp.132-143
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• 1992

The study was conducted to find out synergistic effects by interaction on the basis on anatomical changes between paddy rice and weed species by mixture use of oxyfluorfen and bensulfuron at 0, $10^{-6}$ and $10^{-4}$M, respectively. Tissues were sampled at 72 hrs after soaking treatment and prepared for light microscopic examination and sectioned longitudinally and transversely stem into $8{\mu}m$ thick. As the results of microscopic examination, the major response of treated plant involved rupture and constrict in mesophyll cells and epidermal cells, and shrinks in bundle sheath cells by oxyfluorfen and disorganization and swelling in meristems by bensulfuron. Anatomical changes in rice was the least affected by even high concentration and two herbicide mixtures, whereas Echinochloa crus-galli was severely disorganized in meristem regions and ruptured in epidermal cells by mixture use. Monochoria vaginalis was completely ruptured by any treatment concentrations and mixtures. Scirpus juncoides was considerably tolerant to both herbicides and their mixture and was similar to those that occur in rice. Perennial weed, Sagittaria pigmaea was observed vacuolation, non-nucleation of cell, and irregular cell layering but in mixture injury was slight. Cyperus serotinus was severely shrunk and ruptured by mixture treatment. Eventually anatomical variations in all weed species was shown synergistic effect by use of herbicide mixtures.

• Korean Journal of Dental Materials
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• v.44 no.2
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• pp.171-178
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• 2017

The purpose of this study is to investigate the effect of number of times dipped in coloring liquid and sintering temperature on the flexural strength of zirconia ceramic. In this study, using a zirconia block having improved transparency, specimens with size of $25mm{\times}2mm{\times}1.5mm$ were fabricated. The zirconia ceramic specimens were divided into three groups according to the number of times dipped in coloring liquid by 0, 2 and 4 times, and dyed in the coloring liquid to give color to each specimen. Then, after sintering them at the final temperature of $1,450^{\circ}C$ and $1,600^{\circ}C$, flexural strength was measured using a universal testing machine (total 6 group, n=10 for each group). Also, a scanning electron microscopy (SEM) was performed to observe its microstructure, and the data obtained through the experiment were analyzed with two-way ANOVA. The results of the flexural strength analysis show that the highest value was measured $762.3{\pm}42.3MPa$ in EKL2 group, while the lowest value was $516.4{\pm}77.1MPa$ in EKH4 group. According to the results of the two-way ANOVAs, flexural strength was not related with interaction between sintering temperature and number of times dipped in coloring liquid ($R^2=0.737$). However, there were statistically significant differences in flexural strength depending on sintering temperature (P<0.001). The flexural strength of zirconia ceramics having improved transparency was dependent on sintering temperature. The number of times dipped in the coloring liquid did not affect flexural strength of the zirconia ceramic having improved transparency.

• Journal of Korea Port Economic Association
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• v.34 no.4
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• pp.1-16
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• 2018

The standard shift-share analysis decomposes a region's sectoral growth into three components: national, industry-mix, and regional-shift effects. Nevertheless, the three components of the traditional shift-share are not related to the behavior of the regional economies that are neighbors of the region under analysis. We incorporate a spatial structure within this basic formulation, and consider spatial interaction in the decomposition analysis. Daesan Port's export grew steadily at an annualized average rate of 4.0% during 2011-2017, and its rank, in terms of export performance, was 13 in 2010; this rose to 6 in 2016, then declined slightly to 7 in 2017 before reaching 6 as of June, 2018. However, not all ports have a similar growth path. The Onsan Port's share declined from 27.4% in 2011 to 21.0% to 2017, whereas the share of petroleum product exports of Daesan Port increased rapidly, from approximately 8.5% in 2011 to 16.0% in 2017. The standard shift-share analysis shows that petroleum products and basic petrochemicals have a positive regional in dustry-mix effect, but petrochemistry materials and synthetic resins have a negative sign, indicating that the former's exports grow faster than national export, while the increase of the latter's export is slower than national one. The spatial shift-share model indicates that for both petroleum products and basic petrochemicals, Incheon and Ulsan Ports have a positive value for the neighbor-nation regional shift effect and a positive value for the region-neighbor regional shift effect. This paper also shows that Yeosu Port for petroleum products; Ulsan Port for basic petrochemicals; Ulsan, Onsan and Yeosu Ports for petrochemistry materials; and Ulsan, Busan, and Incheon Ports for synthetic resins have a positive value for the neighbor-nation regional shift effect but a negative value for the region-neighbor regional shift effect.

• Journal of Soil and Groundwater Environment
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• v.14 no.4
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• pp.23-32
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• 2009

The sorption of europium (Eu (III)) onto kaolinite and the influence of humic acids over a range of pH 3 ~ 11 has been studied by batch adsorption experiment (V/m = 250 : 1 mL/g, $C_{Eu(III)}\;=\;1\;{\times}\;10^{-5}\;mol/L$, $C_{HA}\;=\;5{\sim}50\;mg/L$, $P_{CO2}=10^{-3.5}\;atm$). The concentrations of HA and Eu(III) in aqueous phase were measured by UV absorbance at 254nm (e.g., $UV_{254}$) and ICP-MS after microwave digestion for HA removals, respectively. Results showed that the HA sorption onto kaolinite was decreased with increasing pH and their sorption isotherms fit well with the Langmuir adsorption model (except pH 3). Maximum amount ($q_{max}$) for the HA sorption at pH 4 to 11 was ranged from 4.73 to 0.47 mg/g. Europium adsorption onto the kaolinite in the absence of HA was typical, showing an increases with pH and a distinct adsorption edge at pH 3 to 5. However in the presence of HA, Eu adsorption to kaolinite was significantly affected. HA was shown to enhance Eu adsorption in the acidic pH range (pH 3 ~ 4) due to the formation of additional binding sites for Eu coming from HA adsorbed onto kaolinite surface, but reduce Eu adsorption in the intermediate and high pH above 6 due to the formation of aqueous Eu-HA complexes. The results on the ternary interaction of kaolinte-Eu-HA are compared with those on the binary system of kaolinite-HA and kaolinite-Eu and adsorption mechanism with pH was discussed.

• Korean Journal of Soil Science and Fertilizer
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• v.32 no.4
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• pp.429-439
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• 1999

Potentiometric titration data were collected for some humic acids purified from Korean upland and paddy soils over a range of pH (3.0 - 11.0) with $NaNO_3$ background electrolyte concentrations (0.01, 0.10, 0.50 and 1.00 M). The data were applied to model A and V which included both intrinsic heterogeneity of humic materials and electrostatic interaction influences on binding sites. The elemental analysis were conducted for various type of humic samples. The $E_4/E_6$ ratio proposed negative correlation with the total carboxyl groups ($r^2$= 0.9988). The charge ($cmol_c\;kg^{-1}$) on the humic acids became more negative as the ionic strength increased. In both continuous and batch titrations, the ionic strength effect was greater in Namweon series (pH 6.39) than others at pH 5.00. The effect of ionic strength on surface charge appears to be greater in batch titrations. This could suggest that continuous titrations do not represent an equilibrium state and the effects of electrolyte concentration was not fully realized during the course of titrations. Both models described experimental data obtained from continuous and batch titrations well over a range of ionic strengths. Model A is more simpler than model V but adaptes more fitted parameters. Thus, the observed change in apparent binding constants with surface charge is regarded solely due to electrostatic influences rather than functional group heterogeneity. However, Model V is more mechanistically realistic in a number of discrete ligand binding sites.