• Journal of Life Science
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• v.26 no.1
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• pp.129-139
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• 2016

Exercise increases the expression and interaction of major neurotrophic factors such as brain-derived neurotrophic factor (BDNF), insulin-like growth factor-1 (IGF-1), and vascular endothelial growth factor (VEGF) at both central and peripheral tissues, which contributes to improved brain and neural plasticity and cognitive function. Previous findings have been to understand the effect of light or moderate intensity aerobic exercise on neurotrophic factors and cognitive function, not that of high intensity aerobic exercise. However, recent findings suggest that high intensity interval training is a safe, less time-consuming, efficient way to improve cardiorespiratory fitness and weight control, thus American College of Sport Medicine (ACSM)’s guidelines for exercise prescription for various adult populations also recommend the application of high intensity interval training to promote their overall health. High intensity interval training also enhances the expression of BDNF, IGF-1, and VEGF at the brain and peripheral tissues, which improves cognitive function. Increased frequency of intermittent hypoxia and increased usage of lactate as a supplementary metabolic resource at the brain and neural components are considered a putative physiological mechanism by which high intensity interval training improves neurotrophic factors and cognitive function. Therefore, future studies are required to understand how increased hypoxia and lactate usage leads to the improvement of neurotrophic factors and what the related biological mechanisms are. In addition, by comparing with the iso-caloric moderate continuous exercise, the superiority of high intensity interval training on the expression of neurotrophic factors and cognitive function should be demonstrated by associated future studies.

• Journal of Mechanical Science and Technology
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• v.17 no.6
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• pp.796-804
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• 2003

The use of fracture mechanics has traditionally concentrated on crack growth under an opening mechanism. However, many service failures occur from cracks subjected to mixed-mode loading. Hence, it is necessary to evaluate the fatigue behavior under mixed-mode loading. Under mixed-mode loading, not only the fatigue crack propagation rate is of importance, but also the crack propagation direction. In modified range 0.3$\leq$a/W$\leq$0.5, the stress intensity factors (SIFs) of mode I and mode II for the compact tension shear (CTS) specimen were calculated by using elastic finite element analysis. The propagation behavior of the fatigue cracks of cold rolled stainless steels (STS304) under mixed-mode conditions was evaluated by using K$\_$I/ and $_{4}$ (SIFs of mode I and mode II). The maximum tangential stress (MTS) criterion and stress intensity factor were applied to predict the crack propagation direction and the propagation behavior of fatigue cracks.

• International Journal of Precision Engineering and Manufacturing
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• v.2 no.3
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• pp.11-18
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• 2001

A simple and convenient method of analysis for obtaining the individual stress intensity factors in a three-dimensional mixed mode crack is proposed. The procedures presented here are based on the path independence of J integral and mutual or two-state conservation integral, which involves two elastic fields. The problem is reduced to the determination of mixed mode stress intensity factor solutions in terms of conservation integrals involving known auxiliary solutions. Some numerical examples are presented to investigate the effectiveness and applicability of the method for a three-dimensional penny-shaped crack problem under mixed mode. This procedure is applicable to a three-dimensional mixed mode curved crack.

• Journal of the Korean Society for Precision Engineering
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• v.19 no.5
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• pp.81-88
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• 2002

An interface crack of a piezoelectric medium bonded between an elastic layer and a half-space is analyzed using the theory of linear piezoelectricity. Both out-of-plane mechanical and in-plane electrical loads are applied to the piezoelectric laminate. By the use of courier transforms, the mixed boundary value problem is reduced to a singular integral equation which is solved numerically to determine the stress intensity factors. Numerical analyses for various material combinations are performed and the results are discussed.

• KSTLE International Journal
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• v.2 no.1
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• pp.12-16
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• 2001

A finite element analysis of crack propagation in a half-space due to sliding contact was performed. The sliding contact was simulated by a rigid asperity moving across the surface of an elastic half-surface containing single and multiple cracks. Single, coplanar, and parallel cracks were modeled to investigate the interaction effects on the crack growth in contact fatigue. The analysis was based on linear elastic fracture mechanics and the stress intensity factor concept. The crack propagation direction was predicted based on the maximum range of the shear and tensile stress intensity factors.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.20 no.10
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• pp.3408-3414
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• 1996

This paper investigated plane strain stress intensity factors caused by thermal impact on a center-crack strip. The crack was aligned perpendicularly to the strip boundary. The problem was analysed by determining the dislocation density function in the singular integral equations formulated by the dislocation theory. Under the abrupt temperature change along the edge, the center crack behaved as a mode I crack due to the symmetric geometry. The value of maximum stress intensity factor monotonically increased until the ratio of dimensionless crack length approached to about 0.3, followed by gradual decrease. As a result, a critical corresponding crack length was determined.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2001.04a
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• pp.727-730
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• 2001

In many structures a common method of construction is to make use of bolted or riveted joints. With this type of joint the load is transmitted through a pin from one section of the structure to another. Fatigue cracks often start from the edges of holes, due to local stress concentration. In order to predict the fatigue crack growth, the stress intensity factor K for hole-edge cracks should be available. In this paper the stress intensity factors are computed for cracks in bolt-joint region considering the contact condition.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2000.11a
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• pp.481-484
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• 2000

Practical structures are subject not only to tension but also to shear and torsional loading. Even under uniaxial loading, when the load is not perpendicular to the crack plane, mixed mode crack can occur. Hence, it is necessary to evaluate the fatigue behavior under mixed mode loading. In this study, the propagation behavior of the fatigue crack of the STS304 steels under mixed mode loading condition was investigated. The mode I and II stress intensity factors of CTS specimen were calculated using elastic finite element method with experimental results. The fatigue crack propagation under mixed mode was evaluated by the effective stress intensity factor proposed by Tanaka.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 1998.03a
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• pp.123-128
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• 1998

In fracture problems, stress intensity factors obtained theoretically and experimentally have been effectively utilized in the analytical evaluation of the cracks effect. The effect of surface crack of a cylindrical and a hollow cylindrical bar is investigated, as well as the effect of the thickness of a hollow cylindrical bar and inclined crack of a hollow cylinder subjected to torsion moment. In this study, stress intensity factor Km of mode III which expresses the stress state in the neighborhood of a crack tip is used. Stress analysis was conducted of the inside of a hollow cylinder in the axial direction of three dimensional crack tip subjected to torsion moment by combining the caustics method and the stress freezing method.

• Proceedings of the KSME Conference
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• 2001.06a
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• pp.187-192
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• 2001

Cracks in mechanical joints is generally under mixed-mode and there is the critical inclined angle at which mode I stress intensity factor becomes maximum. In order to evaluate the fatigue life of cracks in mechanical joints, horizontal crack normal to the applied load and located on minimum cross section is major concern but critical inclined crack must also be considered. In this paper mixed-mode fatigue crack growth test is performed for horizontal crack and critical inclined crack in mechanical joints. Fatigue crack growth path is predicted by maximum tangential stress criterion using mode I and mode II stress intensity factors obtained from weight function method, and fatigue crack growth rates of horizontal and inclined crack are compared.