• 한국식품위생안전성학회지
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• 제35권5호
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• pp.430-437
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• 2020

본 연구는 전자코와 전자혀 시스템을 이용한 15가지 국내 식품에 대한 맛과 향에 대한 기본 접근 연구를 진행하였다. 먼저 전자혀 시스템을 이용한 샘플의 맛 성분에 대해 상대적인 센서 강도를 제시하였다. 신맛으로 대표되는 SRS 센서에서는 소고기배추국이 가장 높은 9.0을 나타내었고, 미역국에서 가장 낮은 3.7을 나타내었다. 짠맛으로 대표되는 STS 센서는 오징어국에서 가장 높은 8.2를 나타내었고, 소고기배추국이 가장 낮은 1.9를 나타내었다. 감칠맛으로 확인되는 UMS 센서의 경우 소고기배추국이 가장 높은 10.1을 보였고, 달걀국이 가장 낮은 3.3을 나타내었다. 단맛에 관여하는 SWS 센서에서는 비교적 큰차이를 보이지 않았는데, 시금치된장국이 가장 높은 7.3을 나타내었고, 달걀국이 가장 낮은 4.6을 나타내었다. 마지막으로 쓴맛에 기여하는 BRS 센서에서는 시래기 된장국이 가장 높은 7.8을 나타내었으며, 햄김치찌개에서 가장 낮은 4.4를 보였다. 주성분 분석을 통해 5가지 맛 성분과 15가지 샘플에 대한 패턴을 확인한 결과 PC1에서 56.21%의 variance를 확인하였고, PC2에서 25.23%의 variance를 확인할 수 있었다. 각 맛 성분의 경우 SRS 센서의 경우 PC1과 PC2의 factor loading의 경우 -0.95와 -0.20을 나타내었고, STS 센서의 경우 PC1과 PC2의 factor loading의 값이 0.96과 0.14, UMS 센서의 경우 PC1과 PC2의 factor loading의 값이 -0.94와 0.22, SWS 센서의 경우 PC1과 PC2의 factor loading의 값이 0.08과, 0.89, 그리고 BRS 센서의 경우 PC1과 PC2의 factor loading의 값이 0.32와 -0.60을 각각 나타내었다. 군집분석을 통해 확인된 샘플간의 유사도는 크게 4개의 cluster를 확인할 수 있었다. 15가지 샘플에서 확인된 향기성분은 총 25가지 성분이 확인되었고, 모든 샘플에서 상대적으로 가장 높은 함량을 보이는 향기성분은 ethanol과 2-methylthiophene으로 확인되었다. 주성분 분석을 통해 휘발성 향기 성분과 15가지 샘플에 대한 패턴을 확인한 결과 PC1에서 28.54%의 variance를 확인하였고, PC2에서 20.80%의 variance를 확인할 수 있었다. 군집분석의 경우 크게 3개의 cluster로 분류되는 것을 확인할 수 있었다. 이러한 맛과 향에 대한 연구를 통해서 국내 식품에 대한 표준 자료로써의 활용이 가능할 것으로 판단된다.

• 대한전자공학회논문지SP
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• 제42권4호
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• pp.1-12
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• 2005

영상정합은 동일한 장면에 대해서 서로 다른 시간 혹은 서로 다른 특성의 센서로부터 서로 다른 위치에서 얻은 영상들의 위치적 대응관계를 찾는 기법이다. 이 논문에서는 특성이 다른 적외선 센서와 광학 센서로부터 얻은 영상의 정합을 위한 새로운 알고리즘을 제안한다. 지금까지 제안된 서로 다른 특성의 영상을 위한 정합기법은 크게 특징점 기반 영상정합기법과 밝기값 기반 영상정합기법으로 구분될 수 있다. 특징점 기반의 영상정합기법은 정확하게 대응하는 특징점을 선택하는 것이 성능에 결정적인 영향을 준다 그러나 적외선 영상과 가시광선 영상에서는 특징점이 서로 같지 않은 경우가 많기 때문에 강인하지 못하다 그리고 밝기 값 기반의 정합기법에서는 정규상호정보를 유사성 척도로 사용한 영상정합기법이 가장 좋은 성능을 제공하는 것으로 알려져 있다. 그러나 정규상호정보 기반의 영상정합기법은 두 영상의 통계적 상관성이 전역적이어야 한다는 가정을 전제하는데, 적외선 영상과 가시광선 영상에서는 이를 보장하지 못하는 경우가 많아 정규상호정보를 유사성 척도로 사용하는 영상정합기법에서도 좋은 성능을 기대하기 힐들다. 따라서 이 논문에서는 적외선 영상과 가시광선 영상의 통계적 상관성의 해석에 기반한 두 단계 영상정합기법을 제안한다. 정확하고 강인한 정합을 위해서 첫 단계에서는 두 영상에서 통계적 상관성이 높은 부분을 추출하는 ESCR기법과 두 영상을 통계적 상관성이 높도록 필터링하는 ESCF기법을 수행한다. 그리고 두 번째 단계에서는 첫 단계에서의 결과 영상에 대해서 정규상호정보를 유사성 척도로 한 영상정합을 수행한다. 다양한 적외선 영상과 가시광선 영상을 이용한 실험으로부터 제안하는 두 단계 영상정합기법이 기존의 정규상호정보 기반의 영상정합기법에 비해 정확도와 강인함, 그리고 실행 속도의 측면에서 더욱 향상된 성능을 제공함을 확인하였다.

• 대한원격탐사학회지
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• 제37권5_3호
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• pp.1373-1387
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• 2021

산불은 지표 에너지 균형, 사회 및 환경에 중대한 위협을 미치며, 사회경제적 손실을 일으킨다. 한편, 현재까지 널리 사용되고 있는 다중분광 위성 영상 기반 산불 피해 탐지 알고리즘은 구름으로 인한 반사도 오염으로 인해 시의적절한 산불 정보를 얻기 어려운 문제가 있다. 따라서 본 연구에서는 구름에 영향을 받지 않는 유럽우주국의 Sentinel-1 SAR (Synthetic Aperture Radar) 자료로부터 2019년 4월 초에 발생한 남한 강원도의 강릉·동해, 고성·속초 및 인접한 북한의 두 산불 발생 지역을 대상으로 주성분분석(Principal Component Analysis; PCA)을 포함하는 일련의 전 처리 및 K-means clustering을 이용하여 산불 피해 면적을 탐지하였다. 추정된 산불 면적은 국립산림과학원에서 남한의 두 산불에 대해 제공한 산불 피해 면적 및 강도 참조자료 및 산불 피해 탐지에 널리 사용되는 dNBR (differenced Normalized Burn Ratio)을 사용하여 검증하였다. 국립산림과학원의 참조자료 기반 검증에서 강릉·동해와 고성·속초 산불에 대해 평균 약 86%의 정확도를 보였다. dNBR을 사용한 검증에서는 남한 및 북한의 지역 모두에 대해 평균 약 84%의 정확도를 보였다. 이때, 산불 강도가 강할수록 산불 면적 탐지 성능이 높고 반대로 산불 강도가 약할수록 산불 면적 탐지 성능이 낮은 것을 확인할 수 있었다. 본 연구를 통해 검증된 SAR 영상을 이용한 PCA 및 K-means clustering 기반 탐지 알고리즘이 추후 구름의 영향이 크고 작은 산불이 빈번하게 발생하는 한반도에 대하여 신속한 산불 피해 면적 탐지에 활용될 수 있을 것으로 기대된다.

• 벤처혁신연구
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• 제6권1호
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• pp.181-198
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• 2023

본 연구는 의료기관에 종사하는 근로자들의 조직지원인식이 내재적 직무동기에 미치는 영향 관계를 분석하고, 이 과정에서 일-가정 갈등 및 일-가정 균형요인의 인과관계에 대한 유의성 여부도 확인해보고자 한다. 설문지를 통한 실증분석 결과를 살펴보면 다음과 같다. 첫째, 조직지원인식은 내재적 직무동기 뿐만 아니라 일-가정 균형에 유의적인 양(+)의 영향을 미치는 것으로 확인되었고, 일-가정 균형은 내재적 직무동기에 유의적인 양(+)의 영향을 미치는 것으로 확인되었다. 둘째, 조직지원인식은 일-가정 갈등에 유의적인 음(-)의 영향을 미치는 것으로 확인되었으나, 일-가정 갈등은 내재적 직무동기에 유의적인 영향력이 없는 것으로 확인되었다. 셋째, 의료기관 종사자들의 직무스트레스를 줄이기 위해서는 직무강도를 줄이고 능력에 적합한 업무량을 부여하며, 인력운영 및 업무효율성을 제고하기 위해 직무교육과 적재적소의 인력배치가 필요하다. 넷째, 긍정적인 조직지원인식과 내재적 직무동기 향상을 위해서는 현 직장에 대한 애착심을 높일 수 있고 다양한 유인체계로 조직의 문제를 자신의 문제로 인식할 수 있도록 지원 및 제도적 장치를 마련하여 장기근속을 유도하여야 한다. 본 연구의 한계점 및 향후 연구 방향은 다음과 같다. 첫째, 전국의 의료기관 종사자들을 지역별, 성별, 의료기관별, 학업별, 소득별 등으로 분류하여 확장된 분석을 실시하면 더 가치있는 결과를 얻을 수 있을 뿐만 아니라 의료서비스 품질에 대한 평가도 가능할 것으로 사료된다. 둘째, 의료기관 종사자들이 속한 병원의 환경 불확실성이나 경쟁 정도에 따라 직장에서의 일과 개인적인 삶의 균형 지원제도에 대한 영향력이 종업원마다 미치는 정도가 다를 수 있으므로 이를 반영할 필요가 있다. 셋째, 조직지원인식은 조직문화와 조직형태 그리고 조직규모 및 업무특성, 근무연수, 근무유형 등에 따라 다르게 인식될 것이므로 이를 반영할 필요가 있다. 넷째, 최근 정부의 의료기관 정책에 대한 변화와 글로벌 경영환경에 발맞추어 병원들의 조직구조, 직무설계, 조직지원 방식, 동기부여 접근방식, 인사고과의 평가 방법 등 다양한 신 인사관리 기법들을 설문지에 추가하여 분석하는 것이 필요하다. 또한 최근 및 가까운 미래의 의료 트렌드를 반영해서 분석하는 것도 중요하리라 사료된다.

• 대한원격탐사학회지
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• 제39권5_3호
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• pp.979-995
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• 2023

산불은 예측이 어려운 재해이기 때문에 실시간 모니터링을 통해 빠르게 대응하는 것이 중요하며, 정지 궤도 위성 영상은 광역을 짧은 시간 간격으로 모니터링할 수 있어 산불 탐지 분야에 활발히 이용되고 있다. 기존의 위성 영상 기반 산불 탐지 알고리즘은 밝기 온도의 통계량 분석을 통한 임계값 기반으로 이상치를 탐지하는 방향으로 진행되어 왔다. 그러나 강도가 약한 산불을 탐지하기 어렵거나, 적절한 임계값 설정의 어려움으로 일반화 성능이 저하되는 한계점이 있어 최근에는 기계학습을 이용한 산불 탐지 알고리즘들이 제시되고 있다. 현재까지는 random forest, VanillaConvolutional neural network (CNN), U-net 구조 등의 비교적 간단한 기법이 적용되고 있다. 따라서, 본 연구에서는 정지궤도 위성인 Advanced Himawari Imager를 이용하여 동아시아와 호주를 대상으로 State of the Art (SOTA)딥러닝 기법을 적용한 산불 탐지 알고리즘을 개발하고자 하였다. SOTA 모델은 EfficientNet과 lion optimizer를 적용하여 개발하고, Vanilla CNN 구조를 사용한 모델과 산불 탐지 결과를 비교하였다. EfficientNet은 동아시아와 호주에서 0.88 및 0.83의 F1-score를 기록함으로써 CNN (동아시아: 0.83, 호주: 0.78)에 비해 뛰어난 성능을 입증하였다. EfficientNet에 불균형 문제 해결을 위한 weighted loss, equal sampling, image augmentation 기법 적용 시, 동아시아와 호주에서 각각 0.92와 0.84의 F1-score를 기록함으로써 적용 전(동아시아: 0.88, 호주: 0.83)에 비하여 성능이 향상되었음을 확인하였다. 본 연구를 통하여 제시된 SOTA 딥러닝 기법의 산불 탐지에의 적용 가능성과 딥러닝 모델의 성능 향상을 위해 고려해야 할 방향은 향후 산불탐지 분야에 대한 딥러닝 적용에 도움이 될 것으로 기대된다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
• /
• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
• /
• pp.17-17
• /
• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.

• 유통과학연구
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• 제8권3호
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• pp.27-35
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• 2010

실버세대의 중요성은 인구 증가뿐만 아니라 구매력의 향상 및 의사 표현의 강도가 증가하면서 더욱 커지고 있다. 이에 따라 과거 실버세대 전체를 대상으로 접근하던 마케팅 전략은 실버세대의 특성에 따라 적절히 분류하여 접근하는 방식으로 수정되는 것이 적절하다. 또한 세분군 분류 결과에 따라 고객 접근 전략이 결정되므로, 세분군이 얼마나 동일한 특성을 보유하고 있는 지는 마케팅 계획 수립에 매우 중요한 요소가 된다. 따라서 이론적으로 동일 세분군에 속해 있는 고객의 니즈는 대체로 일치해야 한다. 본 연구에서는 실버세대의 생활 행태와 생애 단계를 감안하여, 실버 세대 대상의 마케팅을 위한 세분군 (細分群) 분류를 수행하였으며, 분류된 세분군의 니즈가 얼마나 일치하고 있는지를 측정하기 위하여 동질도 (DoH: Degrees of Homogeneity)를 측정하였다. 동질도는 각 세분군을 대상으로 수행된 설문조사의 객관식 문항 별로 최다 응답자가 선택한 보기 문항이 다른 문항에 비하여 유의미하게 많다고 판단되는 문항의 수를 전체 문항의 수로 나눈 것으로 정의하였다. 본 연구는 동질도를 활용한 세분군 분류 결과의 적절성 평가 방법을 제시하였다는데 의의가 있으며, 다양한 분야에서 응용될 수 있을 것으로 판단된다. 또한 본 연구에서 제시한 실버세대 세분군 분류 결과는 점차 증가하고 있는 실버세대를 위한 마케팅 방안 수립의 기본 자료로 활용될 수 있을 것으로 판단된다.

• 지능정보연구
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• 제18권4호
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• pp.117-127
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• 2012

최근 온라인 소셜 네트워크 서비스(SNS)의 사용자가 크게 늘어나고 있으며 다양한 분야에서 SNS의 사용자 관계 구조 및 메시지를 분석하기 위한 연구를 진행하고 있다. 그러나 대부분의 소셜 네트워크 분석 방법들은 노드 사이의 최단 거리를 기초로 하고 있으므로 계산 시간이 오래 걸린다. 이는 점차 대형화 되어가는 SNS의 데이터를 여러 분야에서 활용하는데 걸림돌이 되고 있다. 이에 따라 본 논문에서는 SNS의 사용자 그래프에서 사용자간 최단거리를 빠르게 찾기 위한 휴리스틱 기반의 최단 경로 탐색 방법을 제안한다. 제안하는 방법은 1) 트리로 표현된 소셜 네트워크에서 시작 노드와 목표 노드를 설정한다. 그리고 2) 만약 목표 노드가 경사 트리의 단말에 있다면 경사 트리가 시작하는 노드를 임시 골 노드로 설정한다. 마지막으로 3) 연결의 차수를 평가값으로 하는 휴리스틱 기반 최단거리 탐색을 수행한다. 이렇게 최단거리를 탐색한 후 매개 중심성 분석(Betweenness Centrality) 및 근접 중심성(Closeness Centrality)를 계산한다. 제안하는 방법을 사용하면 소셜 네트워크 분석에서 가장 많은 시간이 필요한 최단거리 탐색을 빠르게 수행할 수 있으므로 소셜 네트워크 분석의 효율성을 기대할 수 있다. 본 논문에서 제안하는 방법을 검증하기 위하여 약 16만 명으로 구성된 SNS에서의 실제 데이터를 이용하여 매개 중심성 분석과 근접 중심성 분석을 수행하였다. 실험 결과, 제안하는 방법은 전통적 방식에 비하여 매개 중심성, 근접 중심성의 계산 시간이 각각 6.8배, 1.8배 더 빠른 결과를 보였다. 본 논문에서 제안한 방법은 소셜 네트워크 분석의 시간을 향상시켜 여러 분야에서 사회 현상 및 동향을 분석하는데 유용하게 활용될 수 있다.

• 한국의학물리학회지:의학물리
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• 제22권1호
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• pp.42-51
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• 2011

전통적으로 심근 생존능을 식별하고 심근 관류를 정확히 평가하기 위한 도구로 핵의학영상이 이용되고 있으나 경색영역을 정의하기에는 어려움이 있다. 이에 본 연구에서는 극성지도의 분포를 분석하여 특성에 맞는 적응적 임계값을 이용하여 심근경색 모델을 정량적으로 평가하고자 하였다. 쥐 심근경색 모델은 왼쪽 관상동맥을 결찰시켜 제작하였다. 소동물PET 영상은 37 MBq $^{18}F$-FDG를 쥐의 꼬리정맥에 주사한 후 60분 섭취 후 Siemens Inveon SPECT/PET 스캐너를 이용하여 20분 동안 ECG 신호와 함께 획득하였고, OSEM 2D 알고리즘을 이용하여 재구성하였다. PET 영상의 심근 극성지도는 Siemens QGS 소프트웨어에 적합한 형식으로 변환 후 자동으로 심근 벽을 설정하여 작성하였다. 심근경색영역의 기준데이터는 TTC 염색으로 설정하였으며 전체 좌심실대비 염색된 영역의 백분율로 획득하였다. 최적의 임계값 설정을 위해 절대치 설정 방법, Otsu 알고리즘, 다중가우시안혼합모델(Multi Gaussian mixture model, MGMM)을 이용하여 평가하였다. 절대치 설정 방법은 10~90%까지 10%단위로 미리 정의 된 임계값을 이용하였고, Otsu 알고리즘은 영상 내에서 두 군집의 분산을 최대로 하는 임계값으로 설정하였다. MGMM 방법은 영상의 화소 강도를 분석하여 여러 개의 가우시안 분포함수(MGMM2, $\cdots$ MGMM4)로 반복 수행하여 최적의 가우시안 분포를 구하여 적응적 임계값을 설정하였다. 극성지도 평가지표는 각각의 알고리즘에서 측정된 임계값을 이용하여 이진화하고 전체 극성지도와 경색영역의 백분율로 획득한 후, TTC 염색으로 획득된 기준데이터와의 차이를 비교하였다. 그 차이는 절대치 방법의 20%에서 $7.04{\pm}3.44%$, 30%에서 $3.87{\pm}2.09%$, 40%에서 $2.15{\pm}2.07%$이었다. Otsu 방법은 $3.56{\pm}4.16%$이었으며 MGMM 방법은 $2.29{\pm}1.94%$이었다. 소동물 PET 극성지도에서는 30% 임계값이 조직학적 데이터와 비교하여 가장 작은 차이를 보였다. 그러나 TTC 염색으로 측정한 크기가 10% 이하에서는 MGMM 방법이 절대치 방법보다 작은 차이를 보였다(MGMM: 0.006%, 절대치방법: 0.59%). 이 연구에서는 심근경색 모델 평가를 위하여 생체영상 극성지도에서 다중가우시안혼합모델을 이용하여 평가하고자 하였다. MGMM은 사용자의 선택 없이도 자동적으로 영상 특성을 고려하여 적응적 임계값을 찾아주는 방법으로 극성지도에서 심근경색을 평가하는데 도움이 될 것으로 기대된다.