• Journal of The Korean Association For Science Education
• /
• v.19 no.2
• /
• pp.204-216
• /
• 1999

A value can be placed on the integrated science curriculum in terms of producing an insight into solving the routine problem. From such a point of view, the comprehensive concepts which explain the extensive natural phenomena were defined as the integrated themes in this study, and the contents of the integrated science curriculum were developed, as the understanding of the contents focused on the integrated theme enables us to be productive and have an insight. Through analyzing teaching materials, programs and curriculums in relation to the integrated science, five concepts of system, interaction, harmony and balance, structure and function, and circulation were established as the integrated themes, and the nature of each integrated theme was examined. Next, in accordance with the integrated theme, the content of the integrated science curriculum,which are deeper in aspect of the integration level than that of the current science of middle school, were developed. The content of the integrated science curriculum which was proposed in this study is of great significance. in that they provide new perspectives related to our current science curriculum.

• Journal of the Korea Convergence Society
• /
• v.3 no.3
• /
• pp.1-5
• /
• 2012

In this paper, we developed integrated billing system for multi-language. It is very easy to customize for other language and also It has functions in integrated billing system. Whenever administrator insert UI message data for other language, we can make billing packages for its own country to service integrated billing policy.

• Genomics & Informatics
• /
• v.10 no.1
• /
• pp.65-67
• /
• 2012

We have discovered copy number variations (CNVs) in 3,578 Korean individuals with the Affymetrix Genome-Wide SNP array 5.0, and 4,003 copy number variation regions (CNVRs) were defined in a previous study. To explore the details of the variants easily in related studies, we built a database, cataloging the CNVs and related information. This system helps researchers browsing these variants with gene and structure variant annotations. Users can easily find specific regions with search options and verify them from system-integrated genome browsers with annotations.

• Structural Engineering and Mechanics
• /
• v.52 no.1
• /
• pp.205-220
• /
• 2014

This paper is concerned with the modification of multidisciplinary feasible formulation for MDO problems using the integrated coupled approximate models. A drawback of conventional MDFs is the numerical difficulty in decomposing the design variables and deriving the coupled equations of state. To overcome such a drawback of conventional methods, the coupling in analysis and design is resolved by approximating the state variables in each discipline by the response surface method and by modifying the optimization formulation using the corresponding integrated coupled approximate models. The validity, reliability and effectiveness of the proposed method are illustrated and verified through two optimization problems, a mathematical MDF problem and the multidisciplinary optimum design of suspension unit of wheeled armored vehicle.

• Proceedings of the IEEK Conference
• /
• 2008.06a
• /
• pp.233-234
• /
• 2008

Radiation characteristics of a microstrip patch antenna integrated with a UC-EBG (Uniplanar Compact Electromagnetic Bandgap) structure and a Mushroom EBG structure are compared. Radiation characteristics of a patch antenna integrated with a Mushroom EBG structure are better than those of a patch antenna integrated with a UC-EBG structure.

• ETRI Journal
• /
• v.32 no.1
• /
• pp.151-153
• /
• 2010

A highly efficient linear and compactly integrated series-type Doherty power amplifier (PA) has been developed for wideband code-division multiple access handset applications. To overcome the size limit of a typical Doherty amplifier, all circuit elements, such as matching circuits and impedance transformers, are fully integrated into a single monolithic microwave integrated circuit (MMIC). The implemented PA shows a very low idle current of 25 mA and an excellent power-added efficiency of 25.1% at an output power of 19 dBm by using an extended Doherty concept. Accordingly, its average current consumption was reduced by 51% and 41% in urban and suburban environments, respectively, when compared with a class-AB PA. By adding a simple predistorter to the PA, the PA showed an adjacent channel leakage ratio better than -42 dBc over the whole output power range.

• Proceedings of the Polymer Society of Korea Conference
• /
• 2006.10a
• /
• pp.301-301
• /
• 2006

The physical properties of well-defined star-shape polystyrenes with high number of arms (6 to 57 arms) in good and theta solvents were studied using synchrotron X-ray scattering. The scattering profiles for multi-armed polystyrenes shown the molecular shape is changed according to increasing of number of arm. From various parameters which were obtained from scattering profiles, the molecular shape was determined more detail. As results, the molecular shape was changed from a fuzzy-ellipsoid for 6-armed PS to a fuzzy-sphere sphere for 57-armed PS according to increasing of number of arm.

• BMB Reports
• /
• v.55 no.6
• /
• pp.281-286
• /
• 2022

Hepatocellular carcinoma is a major health burden, and though various treatments through much research are available, difficulties in early diagnosis and drug resistance to chemotherapy-based treatments render several ineffective. Cancer stem cell model has been used to explain formation of heterogeneous cell population within tumor mass, which is one of the underlying causes of high recurrence rate and acquired chemoresistance, highlighting the importance of CSC identification and understanding the molecular mechanisms of CSC drivers. Extracellular CSC-markers such as CD133, CD90 and EpCAM have been used successfully in CSC isolation, but studies have indicated that increasingly complex combinations are required for accurate identification. Pseudogene-derived long non-coding RNAs are useful candidates as intracellular CSC markers - factors that regulate pluripotency and self-renewal - given their cancer-specific expression and versatile regulation across several levels. Here, we present the use of microarray data to identify stemness-associated factors in liver cancer, and selection of sole pseudogene-derived lncRNA ZNF204P for experimental validation. ZNF204P knockdown impairs cell proliferation and migration/invasion. As the cytosolic ZNF204P shares miRNA binding sites with OCT4 and SOX2, well-known drivers of pluripotency and self-renewal, we propose that ZNF204P promotes tumorigenesis through the miRNA-145-5p/OCT4, SOX2 axis.

• Journal of Korean Elementary Science Education
• /
• v.29 no.4
• /
• pp.552-566
• /
• 2010

This paper is an in-depth case study to analyze integrated elementary science lesson planning and practical teaching by two teachers at an urban elementary schools. One is an experienced teacher and the other is a beginning teacher. For this study, researchers asked teachers to design 5 stages of lesson planning after sharing basic theories about the integrated science education. The first of the 5 lesson planning stages is curriculum analysis and choice of integrated science topic. The second stage is constructing the frame of integrated science lesson contents, and the third is drawing a diagram of the integrated science lesson development. The fourth stage is making a table of lesson plans, and the last stage is writing integrated science lesson plans. Then, the teachers implemented the lessons they created. They taught students one unit of science which is composed of 8 lessons. Difficulties that teachers meet during designing plans and integrated science class were analyzed. 5 staged lesson planning, video transcriptions, teacher interview about lesson planning and teaching, researchers' checklists, reports of inspection classes, teachers' self evaluation, and students interviews were used for this study. One of the significant results of this study is that both experienced and beginning teachers had many difficulties in deciding on time to teach and contents of science and other subjects, as well as selection and organization of whole topics of integrated science teaching. The beginning teacher especially had greater issues with developing definite teaching-learning strategy to conduct thoughts and views for integrated science at the whole unit and each lesson. However, the experienced teacher was using various teaching-learning strategies by utilizing integrated science teaching professionalism to develop students' integrated thinking ability during the instruction of other subjects. The outcomes of this study are that both teachers could deeply understand the need and value of integrated science education at the elementary school through planning and teaching 8 lessons, and that they could have self-confidence with development of teaching professionalism for integrated science teaching. It may be possible that this study could help the development of pre- and in-service program for improvement of integrated science teaching professionalism for elementary school teacher.

• Journal of the Korean Institute of Rural Architecture
• /
• v.5 no.3
• /
• pp.44-52
• /
• 2003

Past, teacher's facilities space of school arranges the desk by teacher's number and businesslike function a teacher's room and night-duty room, supplementary rest space, of considered 1 room from everything mean. But, these days, teacher's space is emphasized personality of individual study conversation between teachers and a rest etc. Even though the change of such use form is very important to teacher, it is true to be not considered much in architectural planning of existing school's facilities. Plan that correspond dividing use form of school affair meeting and business, individual study, a rest etc. of forward teacher space is to need. Therefore, I wish to suggest architectural data for general and efficient operation management of integrated school through this study.