• 음성과학
• /
• 제15권4호
• /
• pp.43-60
• /
• 2008

Instrumental studies (e.g., aerodynamic, EPG, and EMMA) have shown that the first of two stops in sequence can be articulatorily reduced in time and space sometimes; either gradient or categorical. The current EMMA study aims to examine possible factors_linguistic (e.g., speech rate, word boundary, and prosodic boundary) and paralinguistic (e.g., natural context and repetition)_to induce gradient reduction of $C_1$ in /pk/ cluster sequences. EMMA data are collected from five Seoul-Korean speakers. The results show that gradient reduction of lip aperture seldom occurs, being quite restricted both in speaker frequency and in token frequency. The results also suggest that the place assimilation is not a lexical process, implying that speakers have not fully developed this process to be phonologized in the abstract level.

• 한국지진공학회:학술대회논문집
• /
• 한국지진공학회 1998년도 춘계 학술발표회 논문집 Proceedings of EESK Conference-Spring 1998
• /
• pp.44-51
• /
• 1998

A seismic attenuation formula is derived from the intensity maps of medium sized four earthquakes that occurred in the southern part of Korean peninsula. In order to obtain the seismic attenuation formula, the the coefficients of four attenuation equations representing the intensity maps are integrated using the proper weighting factors depending on the credibility of the data are assigned to. The proposed formula shows the trend of attenuation similar to the ones for the Eastern North America for the region within the epicentral distance of 200km, but produces higher attenuation at farther distances. Though the attenuation curve is not derived from the instrumental data, the result could be a useful tool for the analysis of seismic hazard in Korean peninsula.

• Molecules and Cells
• /
• 제38권8호
• /
• pp.669-676
• /
• 2015

Genome instability, primarily caused by faulty DNA repair mechanisms, drives tumorigenesis. Therapeutic interventions that exploit deregulated DNA repair in cancer have made considerable progress by targeting tumor-specific alterations of DNA repair factors, which either induces synthetic lethality or augments the efficacy of conventional chemotherapy and radiotherapy. The study of Fanconianemia (FA), a rare inherited blood disorder and cancer predisposition syndrome, has been instrumental in understanding the extent to which DNA repair defects contribute to tumorigenesis. The FA pathway functions to resolve blocked replication forks in response to DNA interstrand cross-links (ICLs), and accumulating knowledge of its activation by the ubiquitin-mediated signaling pathway has provided promising therapeutic opportunities for cancer treatment. Here, we discuss recent advances in our understanding of FA pathway regulation and its potential application for designing tailored therapeutics that take advantage of deregulated DNA ICL repair in cancer.

• 한국IT서비스학회지
• /
• 제21권1호
• /
• pp.145-161
• /
• 2022

The data is a key catalyst for the development of the fourth industry, and has been viewed as an essential element of the new industry, with technology convergence such as artificial intelligence, augmented/virtual reality, self-driving and 5 G. This will determine the price and value of the data as the user uses data in which the data is based on the context of the situation, rather than the data itself of the past supplier-centric data. This study began with, what factors will increase the value of data from a user perspective not a supplier perspective The study was limited to public data and users conducted research on users using data, such as analysis or development based on data. The study was designed to gauge the value of data that was not studied in the user's perspective, and was instrumental in raising the value of data in the jurisdiction of supplying and managing data.

• 대한환경공학회지
• /
• 제36권5호
• /
• pp.317-324
• /
• 2014

본 연구는 흡연기작을 모사한 시료채취장비를 이용하여 환경담배연기를 주류연기와 비주류연기로 구분하여 채취하고, 환경담배연기 중의 미량원소성분을 중성자방사화분석을 이용하여 분석하였다. 또한, 실내공기 중 PM2.5를 집중적으로 채취하고 인체 영향이 큰 As, Cr, Mn, Se, V, Zn를 비롯한 약 20종의 미량원소를 분석하여 그 화학적 특성을 파악하며 환경담배연기가 실내공기질에 미치는 영향을 평가하고자 하였다. 담배개피 당 미량원소 발생량은 Cl, K, Na 등을 제외한 대부분의 원소에서 비주류연기에서 더 높게 나타났고, K, Cl, Na, Al의 발생량은 개피 당 $1{\mu}g$ 이상으로 가장 많았고, Br, Fe, Zn도 높은 배출량을 보여 외부오염원과 독립적으로 실내 환경에서의 Br, Cl, Fe, K, Zn의 농도 증가에 환경담배연기가 기여하는 것으로 판단된다. PM2.5의 농도는 흡연 사무실은 $58.7{\pm}18.1{\mu}g/m^3$인 반면, 비흡연 사무실은 $38.6{\pm}12.7{\mu}g/m^3$를 보여 ETS에 의해 흡연 사무실에서 1.5배 정도 높게 나타났고, 미량원소의 농도비는 Cu (1.0)를 제외한 모든 원소에서 농도비의 평균값이 1.1~6.0으로 흡연 사무실의 원소 농도가 비흡연 사무실의 원소 농도보다 높게 나타났다. 이러한 결과는 환경담배연기가 실내 공기 중 PM2.5와 미량원소의 농도 증가의 한 원인인 것을 보여주고 있다.

• 지역사회간호학회지
• /
• 제8권1호
• /
• pp.31-44
• /
• 1997

The purpose of this study was to measure and determine the relationship of femoral neck and lumbar bone mineral density with their and related factors. It were measured and determined the relationships among bone mineral density, bone mineral content in the lumbar and femoral neck, muscle strength (arm, back, leg), muscle endurance, instrumental activity of daily living (IADL), quality of life, cognitive perceptual variables(self efficacy, perceived health status), age, age at menopausal period. The twenty five subjects participating in this study consisted of twelve males and thirteen females at a C-institution in Chung Buk province. The mean age of subjects was 73.64 years. The data was collected from August, 1993 to September, 1993. The data was analyzed with $x^2-test$, t-test, Correlation, multiple regression using a SPSS pc+ program. 1. The mean femoral neck bone mineral density was $0.636g/cm^2$, 66.7% of young bone mineral density, the mean lumbar($L_2-L_4$) bone mineral density was $0.807g/cm^2$, 79.86% of young bone mineral density. The mean fermoral neck bone mineral content was 2.906g and the mean lumbar bone mineral content was 36.898g. 2. The mean muscle strength was 17.14kg(grip strength), 32.05kg(back lift strength), 17.14kg (leg lift strength) and the mean muscle endurance was 9.92times. 3. Men showed a significantly higher score (p<0.01) in muscle strength and muscle endurance than women, as well as a significantly higher score on self efficacy and perceived health status(p<0.05). 4. The femur neck bone mineral density had a significant correlation(p<0.0l) with leg lift strength, back lift strength, and their was a significant correlations (p<0.05) with arm strength and muscle endurance. Lumbar ($L_2-L_2$) bone mineral density had a significant correlation(p<0.05) with muscle endurance, grip strength and IADL. 5. With the multiple regression analysis the most significant predictor for lumbar bone mineral density were IADL, the most significant predictor for femoral neck bone mineral density was leg strength. This study concluded: As the mean bone mineral density and bone mineral content were low, the aged showed osteopenia. Bone mineral density, muscle strength and IADL were correlated. The aged could pro mote muscle strength, bone mineral density and IADL through Leg Press exercise which was safe and efficient for the aged. This Leg Press exercise contributed to prevention of osteoporosis and promoted the health of the aged.

• 한국축산식품학회지
• /
• 제33권1호
• /
• pp.96-102
• /
• 2013

본 연구는 오리 신선육과 냉동 후 해동육의 구별을 손쉽게 할 수 있는 방법을 제시하고, 오리육의 처리형태별 저장기간에 따른 미생물, 드립감량, 관능검사 등 품질변화를 연구하여 기계적 방법(토리미터)을 이용한 신선도 측정 시 객관적인 등급판정 기준을 제시하기 위해 실시되었다. 오리가슴육 중 냉동 후 해동육 껍질(skin)색에서 신선육이나 토치육에 비해 명도가 낮아지고, 적색도가 증가하였으며, 드립감량은 냉동 후 해동육이 다른 처리구에 비해 유의적으로 높았다(p<0.05). 일반 호기성 미생물은 1일차에서 토치육이 신선육에 비해 낮았으나 3 및 7일차에는 모든 처리구간에 유의적인 차이는 없었다. TBARS값은 저장기간 동안 증가하였으나 처리구간 유의적인 차이를 보이지는 않았다. 관능검사결과 냉동 후 해동육이 관능검사의 모든 항목에서 유의적으로 낮은 결과를 나타내었다(p<0.05). 토리미터 값은 오리 가슴 껍질(skin)과 육(meat) 모두에서 냉동 후 해동육이 다른 처리구에 비해 유의적으로 낮게 나타났다(p<0.05). 오리육의 토리미터값과 품질특성과의 상관관계를 분석한 결과 육색을 제외한 일반호기성미생물, 지질산패도, 드립감량 및 저장기간과의 밀접한 관계가 있는 것으로 확인되었다. 이상의 결과에서 냉동 후 해동된 오리 가슴육은 신선육이나 토치육에 비해 육색의 변화나 드립 감량 증가가 빠르게 이루어짐을 알 수 있었고, 토리미터 값의 측정은 냉동 후 해동육을 신선육이나 토치육으로부터 구별하는 신속한 방법으로 이용이 가능할 것으로 사료된다.

• 한국노년학
• /
• 제29권4호
• /
• pp.1277-1293
• /
• 2009

본 연구는 부산지역의 도농복합지역인 기장군 노인을 대상으로 노인의 고독감에 영향을 미치는 요인을 분석한 것이다. 이를 위해 개인적 요인, 건강 요인, 그리고 사회적 요인으로 독립변수를 구분하여 노인 고독감의 영향요인을 살펴보았다. 조사대상은 부산광역시 기장군에 거주하는 65세 이상 노인 138명이며, 사전에 교육된 조사원을 통해 면접조사를 실시하였다. 본 연구의 주요결과는 다음과 같다. 먼저 노인 고독감은 평균 50.6(SD 4.2))로 중간 정도 수준으로 나타났다. 다음으로 도농복합지역 노인의 고독감에 영향을 미치는 요인으로는 개인적 요인 중 생활만족도, 건강요인 중 일상생활수행 정도, 그리고 사회적 요인 중 사회적 지지(정서적 지지와 도구적 지지)와 사회활동참여로 나타났다. 생활만족도와 일상생활수행정도가 낮을수록 고독감이 높은 것으로 나타났으며 정서 및 도구적 지지와 사회활동참여정도가 적을수록 고독감이 높은 것으로 나타났다. 따라서 현재의 노인 서비스를 정서적이고 대인관계적 관점으로 초점이 확대되어야 한다. 그리고 도농복합지역 노인의 고독감을 완화시키기 위한 기존의 사회복지서비스가 수정 및 보완되어야 할 필요가 있으며 노인의 고독감을 감소하기 위해 사회적 지지와 사회활동정도 등과 같은 사회적 요인을 강화하는 방안을 마련해야 한다.

• 한국식품영양학회지
• /
• 제22권4호
• /
• pp.577-586
• /
• 2009

Aging is associated with decreased energy expenditure, thermogenesis and energy requirements. Maintenance of physical fitness of the elderly has been reported to reduce the rate at which the basal metabolic rate, muscle strength, skeletal muscle mass and bone density deteriorate. Skeletal muscle disease is known to increase the risk of physical disability and psychological problems. This study was conducted to investigate changes in disability, emotional problems, body compositions, obesity indices and nutrient intake levels according to physical fitness with the elderly in rural areas. According to the results, physical fitness was negatively related with Activities of Daily Living(ADL, p<0.05), Instrumental Activities of Daily Living(IADL, p<0.001), Body Mass Index(BMI, p<0.001) and abdominal obesity(p<0.05), while it showed a positive correlation with the General Self Efficacy Scale(GSES)(p<0.001) and nutrient intake(p<0.05). When changes in these factors were compared according to the range of quartile of the Fullerton Advanced Balance Scale(FAB Scale), GSES(Q1=35.3, Q2=43.5, Q3=53.2, Q4=51.9, p<0.001), BMI(Q1=36.1%, Q2=34.7%, Q3=33.2%, Q4=28.6%, p<0.01), abdominal obesity(Q1=1.02, Q2=0.99, Q3=0.97, Q4=0.94, p<0.001) and nutrient intake(Q1=71.1%, Q2=75.4%, Q3=80.6%, Q4=80.2%, p<0.05) differed significantly. Taken together, these results suggested that better physical fitness would lead to a reduction in negative factors including physical disability and obesity indices, but to an increase in positive factors such as GSES and nutrient intake. The results of this study are expected to be used as basic data for the development of programs to promote the health of the elderly in a local society.

• 한국병원경영학회지
• /
• 제18권2호
• /
• pp.57-80
• /
• 2013

The purpose of this study is to examine the information search behavior of medical consumers visiting a hospital, and investigate the consumption values of medical consumers, classified according to the information search behavior, and characteristics of online health and disease information. This study also tried to identify the factors affecting medical consumers classified according to information search behavior, and gain an extensive understanding of medical consumers'consumption values and online information use. The analysis results of this study are as follows: First, the consumption values of medical consumers were classified into a total of 7 factors, i.e. future-positive value, family-oriented value, sustainablehealth value, rational-progressive value, social-cooperative value, socialachiever value and hedonistic-individual value. Next, the characteristics of medical consumers'online information search behavior were classified into three types of consumer groups, i.e. the limited information-oriented consumer group, the practical information-oriented consumer group and the passionate information-oriented consumer group. Second, the analysis of the differences among the three groups classified according to the characteristics of the information search behavior in terms of consumption values, use of online information sources, utility and the intention to reuse online information showed that all the differences were statistically significant. The passionate information-oriented consumer group showed the highest scores in the sustainable-health value, the social-achiever value and the hedonisticindividual value. Third, the factors affecting medical consumers, classified into three groups according to the characteristics of the information search behavior, were found to be socio-demographic variables like consumers' age and occupation, consumers'consumption values, use of online information sources, and utility of online information. This study tried to understand what values medical consumers have according to the differences in the information search behavior by examining the consumption values of medical consumers according to the information search behavior. The significance of this study lies in the fact that consumption values are instrumental in understanding medical consumers by identifying the fundamental motives and desires of consumers' behavior.