• Title/Summary/Keyword: Instrumental Factors

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Gradient Reduction of $C_1$ in /pk/ Sequences

  • Son, Min-Jung
    • Speech Sciences
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    • v.15 no.4
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    • pp.43-60
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    • 2008
  • Instrumental studies (e.g., aerodynamic, EPG, and EMMA) have shown that the first of two stops in sequence can be articulatorily reduced in time and space sometimes; either gradient or categorical. The current EMMA study aims to examine possible factors_linguistic (e.g., speech rate, word boundary, and prosodic boundary) and paralinguistic (e.g., natural context and repetition)_to induce gradient reduction of $C_1$ in /pk/ cluster sequences. EMMA data are collected from five Seoul-Korean speakers. The results show that gradient reduction of lip aperture seldom occurs, being quite restricted both in speaker frequency and in token frequency. The results also suggest that the place assimilation is not a lexical process, implying that speakers have not fully developed this process to be phonologized in the abstract level.

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Seismic Wave Attenuation in the Southern Part of Korean Peninsula (한반도 남부의 지진파 감쇠특성)

  • 신진수
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 1998.04a
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    • pp.44-51
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    • 1998
  • A seismic attenuation formula is derived from the intensity maps of medium sized four earthquakes that occurred in the southern part of Korean peninsula. In order to obtain the seismic attenuation formula, the the coefficients of four attenuation equations representing the intensity maps are integrated using the proper weighting factors depending on the credibility of the data are assigned to. The proposed formula shows the trend of attenuation similar to the ones for the Eastern North America for the region within the epicentral distance of 200km, but produces higher attenuation at farther distances. Though the attenuation curve is not derived from the instrumental data, the result could be a useful tool for the analysis of seismic hazard in Korean peninsula.

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Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy

  • Jo, Ukhyun;Kim, Hyungjin
    • Molecules and Cells
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    • v.38 no.8
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    • pp.669-676
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    • 2015
  • Genome instability, primarily caused by faulty DNA repair mechanisms, drives tumorigenesis. Therapeutic interventions that exploit deregulated DNA repair in cancer have made considerable progress by targeting tumor-specific alterations of DNA repair factors, which either induces synthetic lethality or augments the efficacy of conventional chemotherapy and radiotherapy. The study of Fanconianemia (FA), a rare inherited blood disorder and cancer predisposition syndrome, has been instrumental in understanding the extent to which DNA repair defects contribute to tumorigenesis. The FA pathway functions to resolve blocked replication forks in response to DNA interstrand cross-links (ICLs), and accumulating knowledge of its activation by the ubiquitin-mediated signaling pathway has provided promising therapeutic opportunities for cancer treatment. Here, we discuss recent advances in our understanding of FA pathway regulation and its potential application for designing tailored therapeutics that take advantage of deregulated DNA ICL repair in cancer.

A Study on the Data Value: In Public Data (데이터 가치에 대한 탐색적 연구: 공공데이터를 중심으로)

  • Lee, Sang Eun;Lee, Jung Hoon;Choi, Hyun Jin
    • Journal of Information Technology Services
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    • v.21 no.1
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    • pp.145-161
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    • 2022
  • The data is a key catalyst for the development of the fourth industry, and has been viewed as an essential element of the new industry, with technology convergence such as artificial intelligence, augmented/virtual reality, self-driving and 5 G. This will determine the price and value of the data as the user uses data in which the data is based on the context of the situation, rather than the data itself of the past supplier-centric data. This study began with, what factors will increase the value of data from a user perspective not a supplier perspective The study was limited to public data and users conducted research on users using data, such as analysis or development based on data. The study was designed to gauge the value of data that was not studied in the user's perspective, and was instrumental in raising the value of data in the jurisdiction of supplying and managing data.

Indoor Air Quality Pollution of PM2.5 and Associated Trace Elements Affected by Environmental Tobacco Smoke (환경담배연기로 인한 실내공기 중 PM2.5 및 미량성분 오염 특성)

  • Lim, Jong-Myoung;Lee, Jin-Hong
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.5
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    • pp.317-324
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    • 2014
  • Environmental tobacco smoke (ETS) samples were collected separately in mainstream and side-stream smoke using a self-designed smoking machine, and a total 40 of PM2.5 was collected with low volume air sampler at indoor environments with and without ETS in Daejeon, Korea. About 20 trace elements including toxic metals like As, Cr, Mn, Se, V, and Zn were determined in PM2.5 and ETS samples by instrumental neutron activation analysis (INAA). It is found that the emission factors of K, Cl, Na, and Al were much higher than those of toxic elements for both mainstream and side-stream smoke. The average concentration of PM2.5 was enriched by 1.5 times at smoking area ($58.7{\pm}18.1{\mu}g/m^3$) than at smoking free area ($38.6{\pm}12.7{\mu}g/m^3$). The concentration ratio of each element between smoking and smoking free area were ranged from 1.1 to 6.0 except Cu (1.0); especially, Ce (6.0), La (5.2), K (2.3), and Co (2.0) showed higher ratio, which suggests that the ETS is one of the possible increasing factors of PM2.5 and elemental concentration at indoor environment.

A Study of Related Factors in the Bone Mineral Density of the Institutionalized Elderly (시설노인의 골다공증 관련요인 연구)

  • Kim, Hee-Ja
    • Research in Community and Public Health Nursing
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    • v.8 no.1
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    • pp.31-44
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    • 1997
  • The purpose of this study was to measure and determine the relationship of femoral neck and lumbar bone mineral density with their and related factors. It were measured and determined the relationships among bone mineral density, bone mineral content in the lumbar and femoral neck, muscle strength (arm, back, leg), muscle endurance, instrumental activity of daily living (IADL), quality of life, cognitive perceptual variables(self efficacy, perceived health status), age, age at menopausal period. The twenty five subjects participating in this study consisted of twelve males and thirteen females at a C-institution in Chung Buk province. The mean age of subjects was 73.64 years. The data was collected from August, 1993 to September, 1993. The data was analyzed with $x^2-test$, t-test, Correlation, multiple regression using a SPSS pc+ program. 1. The mean femoral neck bone mineral density was $0.636g/cm^2$, 66.7% of young bone mineral density, the mean lumbar($L_2-L_4$) bone mineral density was $0.807g/cm^2$, 79.86% of young bone mineral density. The mean fermoral neck bone mineral content was 2.906g and the mean lumbar bone mineral content was 36.898g. 2. The mean muscle strength was 17.14kg(grip strength), 32.05kg(back lift strength), 17.14kg (leg lift strength) and the mean muscle endurance was 9.92times. 3. Men showed a significantly higher score (p<0.01) in muscle strength and muscle endurance than women, as well as a significantly higher score on self efficacy and perceived health status(p<0.05). 4. The femur neck bone mineral density had a significant correlation(p<0.0l) with leg lift strength, back lift strength, and their was a significant correlations (p<0.05) with arm strength and muscle endurance. Lumbar ($L_2-L_2$) bone mineral density had a significant correlation(p<0.05) with muscle endurance, grip strength and IADL. 5. With the multiple regression analysis the most significant predictor for lumbar bone mineral density were IADL, the most significant predictor for femoral neck bone mineral density was leg strength. This study concluded: As the mean bone mineral density and bone mineral content were low, the aged showed osteopenia. Bone mineral density, muscle strength and IADL were correlated. The aged could pro mote muscle strength, bone mineral density and IADL through Leg Press exercise which was safe and efficient for the aged. This Leg Press exercise contributed to prevention of osteoporosis and promoted the health of the aged.

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Possibility of Instrumental Differentiation of Duck Breast Meat with Different Processing and Storage Conditions (가공 및 저장 방법이 다른 오리 가슴육의 기계적 판별)

  • Sung, Sang Hyun;Bae, Young Sik;Oh, Suk Hwan;Lee, Jae Cheong;Kim, Hyun Joo;Jo, Cheorun
    • Food Science of Animal Resources
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    • v.33 no.1
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    • pp.96-102
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    • 2013
  • The possibility of instrumental differentiation of duck breast meat treated with different processing and storage conditions was investigated for industrial application. Duck breast meats, which were 1) refrigerated (fresh) after slaughter, 2) fresh but applied the torching process for the removal of remaining feathers (fresh-torched), and 3) frozen and thawed (frozen-thawed), were prepared and the torrymeter value and other quality factors were assessed. The torrymeter values of both duck breast meat and skin showed the lowest in frozen-thawed sample during the whole storage period. The drip loss of frozen-thawed sample was higher than those of fresh or fresh-torched ones. The number of total aerobic bacteria was lower in fresh-torched than fresh but both were not different from frozen-thawed at day 1 while no difference found thereafter. Sensory score of frozen-thawed sample was the lowest. The correlation analysis among the torrymeter value and quality factors of duck breast meat revealed that the torrymeter value is closely related with the total aerobic bacterial number, lipid oxidation, drip loss, and storage period but not with color. The results indicate that once the duck breast meat was frozen then thawed, drip loss and sensory quality can be affected and the torrymeter value can differentiate frozen-thawed from fresh and freshtorched duck breast meat.

A Study of Factors Affecting on the Loneliness of the Elderly: Focusing on Urban-rural Complex Area (노인의 고독감에 영향을 미치는 요인에 관한 연구: 도농복합지역을 중심으로)

  • Choi, Song Sik;Park, Hyun Suk
    • 한국노년학
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    • v.29 no.4
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    • pp.1277-1293
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    • 2009
  • This study examined the factors affecting the loneliness of elderly in urban-rural complex area in Busan including personnel factors, health factors, and social factors. To examine the factors affecting the loneliness, 138 older adults, who are 65 years and over, residing Ki Jang in Busan, were interviewed through trained researchers. This study's results include the following. First, the result indicated that means score of loneliness among respondents was 50.6(SD 4.2). Secondly the factors affecting on the loneliness of elderly in urban-rural complex area were life satisfaction of personnel factors, level of activity of daily living of health factors, and social support(emotional and instrumental support) and level of social activity of social factors. So perspective of service of elderly have to expend for diminution of emotional and interpersonal problems. And social welfare service is need to modify and amend for variety policies. This study suggest that further research need in order to reduce loneliness of elderly.

Comparison of Self-living Ability, Obesity Indices and Nutrient Intake according to Physical Fitness among the Elderly in Rural Areas (농촌 지역 일부 노인에서 신체 기능 정도에 따른 활동 제한도, 비만도 및 영양소 섭취 수준의 변화 양상 비교)

  • Suh, Hee-Jae;Kim, Bok-Hee
    • The Korean Journal of Food And Nutrition
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    • v.22 no.4
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    • pp.577-586
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    • 2009
  • Aging is associated with decreased energy expenditure, thermogenesis and energy requirements. Maintenance of physical fitness of the elderly has been reported to reduce the rate at which the basal metabolic rate, muscle strength, skeletal muscle mass and bone density deteriorate. Skeletal muscle disease is known to increase the risk of physical disability and psychological problems. This study was conducted to investigate changes in disability, emotional problems, body compositions, obesity indices and nutrient intake levels according to physical fitness with the elderly in rural areas. According to the results, physical fitness was negatively related with Activities of Daily Living(ADL, p<0.05), Instrumental Activities of Daily Living(IADL, p<0.001), Body Mass Index(BMI, p<0.001) and abdominal obesity(p<0.05), while it showed a positive correlation with the General Self Efficacy Scale(GSES)(p<0.001) and nutrient intake(p<0.05). When changes in these factors were compared according to the range of quartile of the Fullerton Advanced Balance Scale(FAB Scale), GSES(Q1=35.3, Q2=43.5, Q3=53.2, Q4=51.9, p<0.001), BMI(Q1=36.1%, Q2=34.7%, Q3=33.2%, Q4=28.6%, p<0.01), abdominal obesity(Q1=1.02, Q2=0.99, Q3=0.97, Q4=0.94, p<0.001) and nutrient intake(Q1=71.1%, Q2=75.4%, Q3=80.6%, Q4=80.2%, p<0.05) differed significantly. Taken together, these results suggested that better physical fitness would lead to a reduction in negative factors including physical disability and obesity indices, but to an increase in positive factors such as GSES and nutrient intake. The results of this study are expected to be used as basic data for the development of programs to promote the health of the elderly in a local society.

A study on medical consumers'consumption value and online information search characteristics (의료소비자의 소비가치와 온라인 정보탐색 특성에 관한 연구)

  • Ahn, Chang Hee;Ha, Ji Hyun;Lee, Seo Young
    • Korea Journal of Hospital Management
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    • v.18 no.2
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    • pp.57-80
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    • 2013
  • The purpose of this study is to examine the information search behavior of medical consumers visiting a hospital, and investigate the consumption values of medical consumers, classified according to the information search behavior, and characteristics of online health and disease information. This study also tried to identify the factors affecting medical consumers classified according to information search behavior, and gain an extensive understanding of medical consumers'consumption values and online information use. The analysis results of this study are as follows: First, the consumption values of medical consumers were classified into a total of 7 factors, i.e. future-positive value, family-oriented value, sustainablehealth value, rational-progressive value, social-cooperative value, socialachiever value and hedonistic-individual value. Next, the characteristics of medical consumers'online information search behavior were classified into three types of consumer groups, i.e. the limited information-oriented consumer group, the practical information-oriented consumer group and the passionate information-oriented consumer group. Second, the analysis of the differences among the three groups classified according to the characteristics of the information search behavior in terms of consumption values, use of online information sources, utility and the intention to reuse online information showed that all the differences were statistically significant. The passionate information-oriented consumer group showed the highest scores in the sustainable-health value, the social-achiever value and the hedonisticindividual value. Third, the factors affecting medical consumers, classified into three groups according to the characteristics of the information search behavior, were found to be socio-demographic variables like consumers' age and occupation, consumers'consumption values, use of online information sources, and utility of online information. This study tried to understand what values medical consumers have according to the differences in the information search behavior by examining the consumption values of medical consumers according to the information search behavior. The significance of this study lies in the fact that consumption values are instrumental in understanding medical consumers by identifying the fundamental motives and desires of consumers' behavior.

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