• 한국자원식물학회지
• /
• 제21권6호
• /
• pp.431-434
• /
• 2008

Dental caries is the destruction of the enamel of teeth by Streptoccus mutans. S. mutans has been isolated from human dental plaque and is associated with the initial development of enamel lesions. We have studied the antibacterial action of the fruit of Callistemon citrin us against a cariogenic bacterium, S. mutans. From the fruit of C. citrinus, piceatannol (3,3',4',5-tetrahydroxystilbene) was isolated by repeated column chromatography with $SiO_2$ and Sephadex LH-20. Its structure was elucidated by instrumental analysis using 1D-NMR, 2D-NMR and EI-MS. This compound was isolated from the fruit of C. citrin us for the first time. The anticarcinogenic activity of this compound was determined by using agar well-diffusion method and minimal inhibition concentration (MIC).

• International Journal of Advanced Culture Technology
• /
• 제11권1호
• /
• pp.135-146
• /
• 2023

Psychological support is crucial in navigating one's academic and professional lives, especially for students living abroad and pursuing higher education. This study aims to explore the narratives of social support seeking in a group of Korean international graduate students in an urban university setting in the United States. Qualitative research method of narrative approach was used to examine how three Korean graduate students exchanged psychological support. Analysis of interviews, observations, and documents found that four types of social support (informational, instrumental, appraisal, and emotional) were being exchanged and that emotional support was accessible predominantly in individual meetings than in group gatherings. Additionally, the reasons for abstaining from initiating group gatherings are discussed in relation to the Korean culture where participants were mindful of not infringing on each other's time. These findings inform theory on socio psychological support seeking and its relation to cultural values and offer practical insights into psychological support in international students in higher education settings.

• 천문학회보
• /
• 제45권1호
• /
• pp.66.2-66.2
• /
• 2020

We propose a deep learning analysis technique with a convolutional neural network (CNN) to predict the evolutionary track of the Epoch of Reionization (EoR) from the 21-cm differential brightness temperature tomography images. We use 21cmFAST, a fast semi-numerical cosmological 21-cm signal simulator, to produce mock 21-cm maps between z = 6 ~ 13. We then apply two observational effects, such as instrumental noise and limit of (spatial and depth) resolution somewhat suitable for realistic choices of the Square Kilometre Array (SKA), into the 21-cm maps. We design our deep learning model with CNN to predict the sliced-averaged neutral hydrogen fraction from the given 21-cm map. The estimated neutral fraction from our CNN model has great agreement with the true value even after coarsely smoothing with broad beam size and frequency bandwidth and heavily covered by noise with narrow beam size and frequency bandwidth. Our results show that the deep learning analyzing method has the potential to reconstruct the EoR history efficiently from the 21-cm tomography surveys in future.

• 한국식품저장유통학회지
• /
• 제31권3호
• /
• pp.360-373
• /
• 2024

Polychlorinated hydrocarbons are continuously released into the environment from various industrial processes. Trichloroethylene (TCE) and tetrachloroethylene (perchloroethylene, PCE) are of primary concern because of their large-scale production, wide industrial application, poor biodegradability, and tendency to circulate in the air and water. The common routes of human exposure to these compounds include inhalation, ingestion, and dermal adsorption. Additionally, they have been detected in various plant foods. Prolonged exposure to these contaminants is associated with certain risks. They are carcinogenic and have other toxic effects, including gastrointestinal, developmental, neurological, and hematological toxicity. To analyze these contaminants, they are generally extracted from various matrices, followed by instrumental analysis. Gas chromatography, often in combination with different detectors, is the most widely used analytical method. This review covers the toxicity, analytical methods, occurrence in foods, and risk assessment of these contaminants.

• 한국대기환경학회지
• /
• 제16권1호
• /
• pp.79-87
• /
• 2000

This study analyzed the regulations concerning odor management or control in Korea, Japan, and developed countries such as USA and Germany. The Korean restriction standards and measurement methods for offensive odor substances are very similar to the Japanese standards and methods promulgated in 1976. Japan promulgated the odor control act and the specific measurement methods of the offensive odor substances in 1973. In Japan, currently, the local governments can establish their own odor restriction areas and proclaim their own standards suitable for their situations. Also, Japan has more strict regulations and more offensive odor substances to be monitored than Korea. The restriction standards of odor in German is quite similar to the permissible limits and standards of air pollutants at emission sources in Korea. Many states in USA are adopting their own restriction standards and measurement methods, e.q., the ambient air pollution standards, organic functionstest methods by dilation, and establishment and addition of air pollution control equipment at emission sources. Finally, this study analyzed the problems of the regulations, standards, and measurement methods concerning the Korean offensive odor management. Since the direct organic fuctions measurement(DOFMM) method is depending upon the personal sensitives of odor substances, the measurement odor value can be equivocal. That is, the odor measurement value by an examines can differ from that by the other examines. Also, there can be conflicts with the measured odor values depending upon the applied measurement methods, e.q., the DOFMM, the dilation method, and the instrumental analysis method.

• 한국환경농학회지
• /
• 제32권2호
• /
• pp.128-135
• /
• 2013

BACKGROUND: This study was performed to develop a single residue analytical method for new herbicide metazosulfuron in crops. METHODS AND RESULTS: Brown rice, apple, mandarin, Kimchi cabbage and soybean were selected as representative crops, and clean-up system, partition solvent and extraction solvent were optimized. Instrumental limit of quantitation (ILOQ), linearity of calibration curve and method limit of quantitation (MLOQ) were determined based on the chromatography and whole procedures. For recovery tests, brown rice, apple, mandarin, Kimchi cabbage and soybean samples were macerated and fortified with metazosulfuron standard solution at three levels (MLOQ, 10 MLOQ and 100 MLOQ). And then those were extracted with acetonitrile, concentrated, and partitioned with ethyl acetate. Then the extracts were concentrated again and cleaned-up through $NH_2$ (aminopropyl) SPE cartridge with acetone : dichloromethane (1% acetic acid) (20 : 80, v/v) before concentration and analysis with HPLC. CONCLUSION(S): ILOQ of metazosulfuron was 2 ng (S/N${\geq}$10) and good linearity was achieved between 0.05 and 12.5 mg/Kg of metazosulfuron standard solutions, with coefficients of determination of 0.9999. MLOQ was 0.02 mg/Kg. Good recoveries from 74.1 to 116.9% with coefficients of variation (C.V.) of less than 10% were obtained, regardless of sample type, which satisfies the criteria of Korea Food and Drug Administration (KFDA). Those results were reconfirmed with LC-MS (SIM). The method established in this study is simple, economic and efficient to be applied to most of crops as an official and general method for residue analysis of metazosulfuron.

• 분석과학
• /
• 제34권2호
• /
• pp.68-77
• /
• 2021

Cannabis is one of the most abused drugs in Korea. The main psychoactive component in cannabis, Δ9-tetrahydrocannabinol, is metabolized to 11-nor-9-carboxy-Δ9-tetrahydrocannabinol (THCCOOH) and THCCOOH-glucuronide (THCCOOH-glu) in the human liver, whereby the amount of THCCOOH-glu found in urine is twice as high as that of THCCOOH. The analytical process adapted by the majority of urine drug-testing programs involves a two-step method consisting of an initial immunoassay-based screening test followed by a confirmatory test if the screening test result is positive. In this study, a qualitative gas chromatography-mass spectrometry (GC-MS) method was developed and validated for the detection of THCCOOH in human urine, where THCCOOH-glu was converted into THCCOOH by alkaline hydrolysis. For purification of the urine extract prior to instrumental analysis, high-speed centrifugation was used to minimize interference. In addition, an injection-port derivatization method using ethyl acetate and N,O-bis(trimethylsilyl)-trifluoroacetamide containing 1 % trimethylchlorosilane was employed to reduce the time required for derivatization, and an aliquot of the final solution was injected into the GC-MS. The method was validated by measuring the selectivity, limit of detection (LOD), and repeatability. The sensitivity, specificity, precision, accuracy, Kappa, F-measure, false positive, and false negative rate were determined by comparing the GC-MS results with those obtained using the immunoassay. The LOD was determined to be 0.32 ng/mL, while the repeatability was within 9.1 % for THCCOOH. Furthermore, a comparison study was carried out, whereby the screening immunoassay exhibited a sensitivity of 86.4 % and a specificity of 100 % compared to GC-MS. The applicability of the developed method was examined by analyzing spiked urine and forensic urine samples obtained from suspected cannabis abusers (n = 221).

• Nutrition Research and Practice
• /
• 제17권4호
• /
• pp.789-802
• /
• 2023

BACKGROUND/OBJECTIVES: Habitual coffee consumption was inversely associated with type 2 diabetes (T2D) and hyperglycemia in observational studies, but the causality of the association remains uncertain. This study tested a causal association of genetically predicted coffee consumption with T2D using the Mendelian randomization (MR) method. SUBJECTS/METHODS: We used five single-nucleotide polymorphisms (SNPs) as instrumental variables (IVs) associated with habitual coffee consumption in a previous genome-wide association study among Koreans. We analyzed the associations between IVs and T2D, fasting blood glucose (FBG), 2h-postprandial glucose (2h-PG), and glycated haemoglobin (HbA1C) levels. The MR results were further evaluated by standard sensitivity tests for possible pleiotropism. RESULTS: MR analysis revealed that increased genetically predicted coffee consumption was associated with a reduced prevalence of T2D; ORs per one-unit increment of log-transformed cup per day of coffee consumption ranged from 0.75 (0.62-0.90) for the weighted mode-based method to 0.79 (0.62-0.99) for Wald ratio estimator. We also used the inverse-variance-weighted method, weighted median-based method, MR-Egger method, and MR-PRESSO method. Similarly, genetically predicted coffee consumption was inversely associated with FBG and 2h-PG levels but not with HbA1c. Sensitivity measures gave similar results without evidence of pleiotropy. CONCLUSIONS: A genetic predisposition to habitual coffee consumption was inversely associated with T2D prevalence and lower levels of FBG and 2h-PG profiles. Our study warrants further exploration.

• Restorative Dentistry and Endodontics
• /
• 제47권1호
• /
• pp.8.1-8.9
• /
• 2022

Objectives: The aim of this study was to compare the color change of the Giomer resin composite (Beautifil-Bulk) by using photographs obtained with a smartphone (iPhone 6S) associated with Adobe Photoshop software (digital method), with the spectrophotometric method (Vita Easyshade) after immersion in different pigment solutions. Materials and Methods: Twenty resin composite samples with a diameter of 15.0 mm and thickness of 1.0 mm were confectioned in A2 color (n = 5). Photographs and initial color readings were performed with a smartphone and spectrophotometer, respectively. Then, samples were randomly divided and subjected to cycles of immersion in distilled water (control), açai, Coke, and tomato sauce, 3 times a day, 20 minutes for 7 days. Later, new photographs and color readings were taken. Results: The analysis (2-way analysis of variance, Holm-Sidak, p < 0.05) demonstrated no statistical difference (p < 0.005) between the methods in all groups. Similar color changes were observed for all pigment solutions when using the spectrophotometric method. For the digital method, all color changes were clinically unacceptable, with distilled water and tomato sauce similar to each other and with statistical differences (p < 0.005) for Coke and açai. Conclusions: Only the tomato sauce produced a color change above the acceptability threshold using both methods of color assessment. The spectrophotometric and digital methods produce different patterns of color change. According to our results, the spectrophotometric method is more recommended in color change assessment.

• 대한환경공학회지
• /
• 제37권4호
• /
• pp.240-245
• /
• 2015

본 연구에서는 대전광역시 동구를 중심으로 공중화장실에 대하여 악취강도를 공기희석관능법과 기기분석을 통하여 공중화장실관리 및 악취저감대책 수립에 기초자료로 제공하고자 하였다. 악취희석배수는 소변기실에서 10~669, 대변기실에서는 31~464까지 다양하게 나타났다. 한편 민원이 발생할 수 있는 악취강도 2.5도 이상의 악취가 발생하는 곳은 6개소(33%)로 조사되었다. 수세식 발효식 재래식처리방식의 대변기실과 설치년도에 따라 악취강도는 차이가 있으나, 화장실 면적은 차이가 없다. 악취원인물질 확인을 위한 6개 공중화장실을 대상으로 기기분석결과 NH3 최대농도는 2.04 ppm, 평균농도는 0.67 ppm이며, $H_2S$, $CH_3SH$, $(CH_3)_3N$는 검출되지 않았다. 발효식과 재래식공중화장실에는 비누, 방향제, 쓰레기통이 없었다. 화장지는 수세식 화장실의 50%에만 있었다.