• Title/Summary/Keyword: Institutional review board

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Eyelid Tumors: Clinical Data from an Eye Center in Ankara, Turkey

  • Gundogan, Fatih Cakir;Yolcu, Umit;Tas, Ahmet;Sahin, Omer Faruk;Uzun, Salih;Cermik, Hakan;Ozaydin, Sukru;Ilhan, Abdullah;Altun, Salih;Ozturk, Mustafa;Sahin, Fahri;Erdem, Uzeyir
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.10
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    • pp.4265-4269
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    • 2015
  • Introduction: The aim of the study was to explore the distribution of eyelid tumors in Ankara, the capital city of Turkey, from a histopathological point of view. Materials and Methods: Medical records of 1,502 patients who had eyelid surgery because of tumoral lesions were retrospectively reviewed after obtaining institutional review board approval. A total of 1,541 lesions with histopathologic diagnosis were included. Inflammatory tumoral lesions were excluded. The lesions were categorized into three groups according to the origin: epidermal, adnexal tumors and 'others', including melanocytic, neural and vascular lesions. Results: Of the total of 1,541, 908 lesions were epidermal in origin. Only 22 (1.5%) were malignant, and 6.0% was premalignant lesions such as actinic keratosis and Bowen's disease. Twenty-one of 22 malignant lesions were basal cell carcinoma. There was only one patient with squamous cell carcinoma and no sebaceous cell carcinoma. Among the benign tumors (92.5%), squamous papilloma was the most frequent (21.8% of all lesions). The other frequent lesions were nevus (17.6%), seborrheic keratosis (17.3%), hydrocystomas (10.6%), xanthelasma (7.6%) and epidermal cysts (7.2%). Conclusions: The results of this study are in accordance with published literature. The absence of sebaceous cell carcinomas needs to be stressed.

Clinical Outcomes of Percutaneous Plasma Disc Coagulation Therapy for Lumbar Herniated Disc Diseases

  • Kim, Sang-Hyun;Kim, Sung-Chul;Cho, Ki-Hong
    • Journal of Korean Neurosurgical Society
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    • v.51 no.1
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    • pp.8-13
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    • 2012
  • Objective : This is prospective study of clinical outcomes of percutaneous plasma disc coagulation Therapy (PDCT) in patients with herniated lumbar disc disease (HLD) to evaluate the safety and efficacy in its clinical application and usefulness as a reliable alternative to microscopic discectomy. Methods : Forty-six patients were enrolled in this study from April 2006 to June 2010. All patients had one-level HLD. Disc degeneration was graded on routine T2-weighted magnetic resonance Image (MRI) using the Pfirrmann's grading system and all index levels were grade 3 and grade 4. Indications for surgery were radiculopathy caused by disc protrusion with soft consistency. MRI was done at one month after the procedure in all patients to check post-PDCT change. The clinical outcomes were evaluated using Visual Analog Scales (VAS) score and MacNab's criteria. Results : This study was approved by the Institutional Review Board of our institution. The age of the study population ranged from 16 to 59 years with a mean age of 37.2 years. There were 29 males and 17 females in this study. The mean period of clinical follow-up was 21 months. The average preoperative VAS score for radiculopathy was $7.4{\pm}1.4$, while the final follow-up VAS score was $1.4{\pm}0.7$ (p<0.001). In MacNab's criteria, 41 patients (89.1%) had achieved favorable improvement (excellent and good) until later follow-up. There were one patient from infection and two patients who needed to convert to open discectomy. Conclusion : PDCT is a safe and efficient treatment modality in a selective patient with HLD.

A Study on the Falls, Fear of Falling, Depression, and Perceived Health Status among the Older Adults (노인의 낙상, 낙상에 대한 두려움, 우울, 지각된 건강상태에 관한 연구)

  • Jung, Duk-Yoo;Shin, Kyung-Rim;Kang, Youn-Hee;Kang, Ji-Sook;Kim, Kon-Hee
    • Korean Journal of Adult Nursing
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    • v.20 no.1
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    • pp.91-101
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    • 2008
  • Purpose: The purpose of this study was to investigate the relationships between a experience of falling, fear of falling, depression, and perceived health status in urban areas. Methods: After obtaining Institutional Review Board (IRB) approval, a one-time, face-to-face, and private interview was conducted with each participant who was eligible and agreed to participate in this study from May 2007 to August 2007 by trained graduate-level nursing students. The questionnaires consisted of Fall Efficacy Scale, K-GDS, and SF-36. The collected data were analyzed with SPSS/PC 12.0 program, which was used for frequency, percentage, mean, standard deviation, t-test, and hierarchical regression. Results: The major findings of this study were as follows; 1) approximately 9% of participants had fallen within one year. Study participants reported moderate fear of falling(M=43.80); moderate physical health (M=42.31) and mental health(M=46.05); and low depression status(M=10.38). 2) there were significant differences in fear of falling according to gender, experience of falling, exercise, and depression. 3) significant factors influencing on fear of falling were experience of falling and physical health status. Conclusion: The results of this study indicate that nurses working closely with older adults should be taught the impact of previous falls and physical health status on fear of falling and need to reinforce exercise behavior for older adults who are vulnerable to fear of falling.

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Clinical Outcomes of Gamma Knife Radiosurgery for Metastatic Brain Tumors from Gynecologic Cancer : Prognostic Factors in Local Treatment Failure and Survival

  • Shin, Hong Kyung;Kim, Jeong Hoon;Lee, Do Heui;Cho, Young Hyun;Kwon, Do Hoon;Roh, Sung Woo
    • Journal of Korean Neurosurgical Society
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    • v.59 no.4
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    • pp.392-399
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    • 2016
  • Objective : Brain metastases in gynecologic cancer (ovarian, endometrial, and cervical cancer) patients are rare, and the efficacy of Gamma Knife Radiosurgery (GKRS) to treat these had not been evaluated. We assessed the efficacy of GKRS and prognostic factors for tumor control and survival in brain metastasis from gynecologic cancers. Methods : This retrospective study was approved by the institutional review board. From May 1995 to October 2012, 26 women (mean age 51.3 years, range 27-70 years) with metastatic brain tumors from gynecologic cancer were treated with GKRS. We reviewed their outcomes, radiological responses, and clinical status. Results : In total 24 patients (59 lesions) were available for follow-up imaging. The median follow-up time was 9 months. The mean treated tumor volume at the time of GKRS was $8185mm^3$ (range $10-19500mm^3$), and the median dose delivered to the tumor margin was 25 Gy (range, 10-30 Gy). A local tumor control rate was 89.8% (53 of 59 tumors). The median overall survival was 9.5 months after GKRS (range, 1-102 months). Age-associated multivariate analysis indicated that the Karnofsky performance status (KPS), the recursive partitioning analysis (RPA) classification, and the number of treated lesions were significant prognostic factors for overall survival (HR=0.162, p=0.008, HR=0.107, p=0.038, and HR=2.897, p=0.045, respectively). Conclusion : GKRS is safe and effective for the management of brain metastasis from gynecologic cancers. The clinical status of the patient is important in determining the overall survival time.

The relationship between dental hygiene problems and dental hygiene planning according to oral health status (구강건강상태에 따른 치위생문제와 치위생계획의 연관성)

  • Kang, Hyun-Kyung;Kim, Yu-Rin
    • Journal of Korean society of Dental Hygiene
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    • v.18 no.5
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    • pp.665-674
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    • 2018
  • Objective: The purpose of this study was to reduce the burden on dental hygienists in performing dental hygiene processes in the clinic. This study systematically analyzed dental hygiene problems and dental hygiene planning according to the oral condition of patients by applying an oral health care program based on the dental hygiene process. Methods: This study analyzed influential factors of 17 dental hygiene problems and 12 dental hygiene plans according to the oral health index and charts of 185 patients. This study was approved by the Institutional Review Board (IRB No. 1041449-201801-HR-003) of Silla University. The frequency of dental hygiene problems and dental hygiene planning was analyzed and correlations among the oral health index, dental hygiene problems, and dental hygiene planning were analyzed. Results: The higher the bleeding on probing score was, the more scaling was planned. The higher the calculus rate was, the more air-jet and jaw joint disorder prevention education was planned. The higher the O'Leary index was, the more dietary education and air-jet was planned. The higher the Simplified Oral Hygiene Index was, the more air-jet and jaw joint disorder prevention education was planned. The higher the Periodontal Screening and Recording index was, the more scaling and professional tooth cleaning was planned (p<0.05). Conclusions: The burden of oral preventive duties on dental hygienists will be minimized by systematically establishing problems and planning of dental hygiene according to patients' oral health index scores. Therefore, it is expected that dental hygienist can actively use the dental hygiene process in oral health care programs.

Fluoride concentration in the finger nails of dental hygiene and nonhealth-relate some female students (치위생과와 비보건학과 일부 여대생의 손톱 내 불소농도 차이)

  • Oh, Na-Rae;Park, Eui Jung;Yoon, Sung-Uk
    • Journal of Korean society of Dental Hygiene
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    • v.16 no.1
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    • pp.147-153
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    • 2016
  • Objectives: The purpose of the study is to investigate the relationship between fluorine concentration within finger nails and the level of dentifrice in dental hygiene students and non-health majoring students. Methods: A self-reported questionnaire was completed by seventy female college students living in Daegu and Gyeongbuk that are not supplied with fluoridation from May to June, 2014. Informed consent was approved by institutional review board (IRB). The questionnaire consisted of general characteristics of the subjects (11 items) and oral health behavior including number of toothbrushing, duration of toothbrushing, number of mouth rinsing, and amount of dentifrice. A dentist and a dental hygienist examined directly the subjects by the guideline of World Health Organization (WHO). The oral examination included decayed tooth, healthy tooth, and filled tooth. The nail samples were obtained from seventy female students. Results: Comparing the dental hygiene students and non-health majoring students, 62.5% of dental hygiene students used approximately 1300mg of dentifrice and 55.2% of non-health majoring students used 1800mg or more of dentifrice. The non-health majoring students used more dentifrice (p<0.01). The fluorine concentration within nails was $1.9905{\mu}l/g$ in dental hygiene students and $3.2149{\mu}l/g$ in non-health majoring students. The fluorine concentration within nails in the dental hygiene students was significantly lower(p<0.01). Conclusions: The accumulation of fluoride in human body is not fully caused by dentifrice. However, The accumulation may occur due to toothbrushing so that it is necessary to educate the students about the right use of the dentifrice.

Terminal Care Stress, Job Satisfaction and Terminal Care Performance for Nurses in Internal Medicine Wards (내과병동 간호사의 임종간호 스트레스, 직무만족도 및 임종간호수행)

  • Baek, Eu Kyoung;Choi, Eun Joung
    • Journal of Hospice and Palliative Care
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    • v.18 no.4
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    • pp.267-275
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    • 2015
  • Purpose: This study is aimed to investigate the relationship among terminal care stress, job satisfaction and terminal care performance nurses in internal medicine wards and to provide a basis to improve terminal care performance. Methods: This is a descriptive study performed with 201 nurses who have at least one year of experience and are stationed at the internal medicine department of three general hospitals and three university hospitals in P city of a metropolitan city B. The nurses also had an experience with a dying patient. Data were collected from March 1 through March 31, 2014. The study was approved by the Institutional Review Board of Kosin University. Results: Job satisfaction was negatively correlated with stress in end-of-life care (r=-212, P=0.003) and positively correlated with terminal care performance (r=0.383, P<0.001). There was no correlation between terminal care stress and terminal care performance. Conclusion: Appropriate programs are needed to improve job satisfaction for high quality terminal care performance.

Reliability and Validity Analysis of a Standard Instrument of Diagnosis and Assessment for Spleen Qi Deficiency Pattern in Chronic Dyspepsia Patients (비기허증(脾氣虛證) 진단평가도구의 신뢰도 및 타당도 예비 평가: 만성 소화불량 환자 대상 설문지 검증 임상시험)

  • Kim, Jihye;Kim, Juyeon;Kim, Jinsung;Kim, Keun Ho
    • The Journal of Korean Medicine
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    • v.36 no.3
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    • pp.23-34
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    • 2015
  • Objectives: This study is aimed at assessing the reliability of a standard instrument of diagnosis and assessment for Spleen Qi deficiency pattern questionnaire (SQDQ) and examining the validity of the SQDQ by comparing the pattern identification scores of different groups. Methods: We conducted a survey of 72 participants (60 patients with chronic dyspepsia and 12 healthy subjects) using self-reported questionnaire. Participants were given written consent and this study was performed under the permission of institutional review board of Kyung-Hee university Korean medicine hospital. Results: The reliability and the validity of the questionnaire were inspected. Internal consistency of the SQDQ was excellent. Construct validity analyzed by exploratory factor analysis produced 4 factors, which were selected from eigenvalues that are greater than 1.0. The factor 1, 2, 3 and 4 showed 'fatigue', 'meal', 'diagnosis' and 'figure' respectively. For most of SQDQs' items, there were significant differences observed between the Spleen Qi and the non-Spleen Qi groups. However, the 'emaciation', 'tongue diagnosis' and 'pulse diagnosis' showed no significant differences. Conclusions: The SQDQ restructured in this study may provide a fundamental questionnaire and a further study is required for a more advanced, standardized and statistically proven questionnaire.

Trends of Chuna Manual Therapy on Traffic Accident in Korea from 2005 to 2014 (최근 10년간 교통사고 환자의 추나치료에 대한 국내 연구 동향)

  • Jeon, Yong-Tae;Park, Sang-Hun;Han, Kuk-In;Lee, Jung-Han;Ko, Youn-Seok
    • Journal of Korean Medicine Rehabilitation
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    • v.25 no.2
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    • pp.89-96
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    • 2015
  • Objectives This study is to investigate domestic trends of chuna manual therapy on traffic accident for recent 10 years. Methods We searched the studies on chuna manual therapy for traffic accident in 6 Korean web databases. Consequently, 17 research papers were founded. We analyzed these papers according to their published year, the titles of journal, the type of study, the number of cases, the sites of injury, assessment scales of study, and ethics of research. Results 17 papers were published since 2005. The studies on chuna manual therapy about traffic accident were mainly published in the journal of korean society of chuna manual medicine for spine & nerves and the journal of korean medicine rehabilitation. All papers were clinical research include 2 case series, 2 non randomized controlled trials (NRCTs), 13 randomized controlled trials (RCTs). The most frequently occured symptom was neck pain. In assessment scales, visual analog scale (VAS) was mainly used. All clinical studies were not mentioned about approval of institutional review board (IRB). Conclusions In this study, we analyzed the trends of chuna manual therapy on traffic accident in Korea from 2005 to 2014. In reviewing published papers, we found several weak points in methods of research and quality of study protocol. It is needed to adjust these problems for development of future researches.

Relationship between Visceral Adipose Tissue and Oriental Obesity Pattern Identification in Obese Korean Women (비만여성에서 내장지방과 한방비만변증의 연관성)

  • Kim, Eun-Joo;Lee, A-Ra;Hwang, Mi-Ja;Cho, Jae-Heung;Choi, Sun-Mi;Chung, Seok-Hee;Song, Mi-Yeon
    • Journal of Korean Medicine Rehabilitation
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    • v.21 no.2
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    • pp.279-288
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    • 2011
  • Objectives : Our purpose of this study was to evaluate the association between abdominal adipose tissue and oriental obesity pattern identification. Methods : This study was performed in 78 healthy obese(BMI(body mass index)${\geq}25kg/m^2$) women in Seoul. Subjects underwent abdominal CT(computed tomography) scanning and were asked to complete the oriental obesity pattern identification questionnaire. Subjects were given written consent and this study was performed under permission of institutional review board of Kyung-hee East-west Neo medical center. Results : 1. VFA(visceral fat area) and VSR(visceral/subcutaneous adipose tissue ratio) were significantly correlated with stagnation of the liver qi(肝鬱, gan-yu)(p<0.05). But, other patterns were not significantly correlated with oriental obesity pattern identification(p>0.05). 2. We evaluated a difference of oriental obesity pattern identification score in visceral obesity group(n=34) versus non-visceral obesity group(n=44). Scores of all patterns except food accumulation(食積, shi-ji) were significantly higher in the visceral obesity group than in the non-visceral obesity group(p<0.05). Especially, there was a further significant difference in stagnation of the liver qi(肝鬱, gan-yu)(p<0.01). Conclusions : Generally, the stagnation of the liver qi(肝鬱, gan-yu) has a close relation with stress and depression. This study suggests that stress and depression might be correlated with visceral fat, and the use of oriental obesity pattern identification would be helpful for planning a treatment schedule of visceral obesity in the clinic.