• Journal of Radiation Industry
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• v.3 no.1
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• pp.13-18
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• 2009

In earlier investigations, seeds of Perilla frutescens(L.) Britt. cv. Chookyoupjaso were irradiated with 200 Gy gamma ray to generate mutagenesis. The aim of this study is to investigate the effects of a hexane extract from Perilla frutescens (L.) Britt. cv. Chookyoupjaso mutant 45 on the actions of anti-inflammatory activity on inducible nitric oxide synthase, and an identification of the major active compound. The hexane extract from P. frutescens exhibited activity of inhibition of a NO production ($IC_{50}$, $295.1{\mu}g\;ml^{-1}$). The hexane extract was further divided into subfractions by silica-gel chromatogarphy. Inhibition of the NO production by various fractions was assayed in LPS-stimulated RAW 264.7 cells. Among the seven fractions, the 5th fraction was the most effective ($IC_{50}$, $19.5{\mu}g\;ml^{-1}$). The 5th fraction suppressed the expression of protein of iNOS in LPS-induced RAW 264.7 cells, and GC/MS analyses showed that isoegomaketone is a major bio-active compound in the 5th fraction. The result indicated that isoegomaketone has a good potential to be developed as an anti-inflammation agent.

• International Journal of Computer Science & Network Security
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• v.21 no.8
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• pp.43-50
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• 2021

For the implementation of innovative products or services companies use different innovation strategies, in particular, outsourcing is quite widespread, given the high level of specialization and professionalism of companies that provide such services. The aim of this article was to evaluate the link between outsourcing of innovative activities and indicators of companies' efficiency. The methodology of the research includes the methods of correlation analysis and regression analysis to reveal the correlation between the use of outsourcing of innovative products and services and the turnover of the EU enterprises. The results show a high level of innovative activity of EU enterprises (50.3% innovatively active). Innovative business processes are the most widespread form of innovation activity (41% of enterprises implement business processes, and the indicator is higher than 41% in the most developed EU countries). The turnover of enterprises with new or substantially improved products was found to grow by 10.92% for the period 2016-2018. The correlation analysis shows weak direct links between the indicator of turnover growth and the number of enterprises that have independently implemented innovations, or have implemented innovations jointly with third-party companies, or using outsourcing services. The highest level of direct connection was found between the growth of turnover of enterprises that launched a new product for the market and the growth of the number of enterprises that implemented innovations with the involvement of organizations (correlation 0.273). Based on the regression analysis it was found that with a 1% change in the growth rate of the number of innovation-active enterprises, the growth rate of turnover from new or improved products increased by 5.67%. At the same time, with a 1% change in the growth rate of the number of enterprises that implement innovation through outsourcing, the growth rate of turnover from new or improved products will increase by 7.15%.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.2
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• pp.565-577
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• 2020

This study empirically examined how a firm size affects the determinants of innovative activities using the data of the Korean Innovation Survey (KIS) 2016. With data from 2,003 firms in the manufacturing sector, we performed logistic regression analysis and zero-inflated negative binomial regression analysis. R&D expenditure and patent applications were used as proxies for innovative activity. The independent variables included the firm's characteristics variables such as the firm's age, tech-level industry, RDemp (R&D employee ratio), venture, export, and industrial characteristics variables such as networking, appropriability, and spillovers. The empirical findings are that there are some differences in firms' innovative activity determinants among the firms' size groups. Next, strategic appropriability has negative impacts on small firms' R&D expenditure and medium-firms' patents. Networking is an important determinant of innovative activity for all firms, except for large firms. Furthermore, in deciding R&D activities, small and medium-sized firms were significantly influenced by industrial characteristics as compared to that of large firms. Our findings suggest some R&D promotion policies. Policies fostering firms' technological interaction would allow firms to take advantage of technological spillovers and thus raise the probability of investing in R&D.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.35 no.2
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• pp.147-154
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• 2012

In the manufacturing industry, fostering talented workers has become a core activity as well as an important resource leading to manufacturing enterprises' innovative activities, which has come to the fore as one of the biggest success factors for innovative activities indeed. In other countries, there are many researches actively conducted on talent-fostering programs related to manufacture innovation. In Korea, however, manufacturers or several different education agencies don't actively carry out manufacture innovation instructions and have failed to faster special competent workers since their instructions focus on theories most of the time. Therefore, this study was conducted to understand the present conditions of manufacture-innovative instructions in Korea by classifying them in a method of educational technology and to investigate various teaching methods through oversea cases and cases from non-manufacture fields so that it might make a proposal for a better manufacture-innovative instruction method.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.4
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• pp.317-324
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• 2020

The study aims to analyze the theoretical background of the economic growth and sustainable development; systematization of scientists view on monitoring and economic and innovative evaluation, analysis and diagnosis of factors affecting these processes. Rating characteristics of the level of innovative resources development obtained based on the comparative analysis of Kazakhstan regions. Calculations were done based on official statistics during 2010 and 2015-2017. Based on obtained data there has been grading of the country regions and their ratings were determined by the level of development of innovative resources. This research identifies areas and mechanisms to ensure balanced sustainable development of the national economy. The findings suggest that sustainable development of the state is affected by the innovative activity of the regions, the sustainable development of which is ensured by innovative enterprises. Transition to the model of sustainable territorial development involves the formation of such conditions and the use of mechanisms under which the natural base of this development is not destroyed, the environment suitable for human existence is preserved and reproduced. The findings of this research support for pursuing a national policy of reducing regional imbalances, and promoting a more balanced and sustainable development of the whole country.

• Korean small business review
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• v.42 no.3
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• pp.245-274
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• 2020

The 4th Industrial Revolution is rapidly changing the business environment and enterprises are required to accelerate various innovative activities for sustainable competitiveness. Recently corporate entrepreneurship is widely spread to organization for establishing innovative corporate culture and stimulating corporate ventures. However, many enterprises are not successful and productive due to lack of readiness of corporate entrepreneruship. Therefore, finding the factors influencing corporate entreprensurship, innovative activities and business performance is a very important research issues. A research model and hypothesis are developed by through literature review to analyze positive effects of corporate entrepreneurship to corporate performance and influential effects of factors such as innovation-based efforts at the organizational level, vision and organizational strategies and innovative operating system to corporate entrepreneurship and business performance. The result of Entrepreneurship Survey with Corporates conducted by Korea Entrepreneurship Foundation in 2017 is used for the research sample. Hypothesis test used 1,326 samples and the structural equation modeling is applied. The results show that corporate entrepreneurship improves innovative idea activity performance and business performance. And, establishing innovative vision and strategies and innovative organizational culture enhances corporate entrepreneurship. In addition, it was confirmed that the innovative operational system has a moderating effect that strengthens the positive influence relationship between corporate entrepreneurship and innovative idea performance. The results of this study have implications for previous research on corporate entrepreneurship in Korea by presenting the relationship between corporate entrepreneurship and business performance and the multilateral relationships between innovative organizational structure and corporate entrepreneurship.

• Knowledge Management Research
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• v.21 no.1
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• pp.1-25
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• 2020

Although patents have mainly been considered as the results of the invention process, of late their value as strategic assets have increasingly been emphasized. Consequently, the competition for patents among firms has intensified, and the number of patent disputes have been steadily increasing. Patent disputes, which cause enormous expense and resource utilization, increase uncertainty and have been considered as a threat or problem for the firms involved. Patent disputes are expected to have a significant impact on the decision making about subsequent innovation activities. This study attempts to analyze the effect of patent disputes on the subsequent innovative activities of the firms that are sued. After experiencing litigation as defendants, we examine their subsequent patenting strategies. According to the results of the study, firms who are experiencing patent litigation are more likely to achieve high-quality patents and cite recent technology when they apply for patents. Meanwhile, patent litigation experience has been shown to negatively affect the amount of subsequent patents applied. This study increases understanding by examining whether patent disputes, which have been mainly recognized negatively as obstacles, can be an opportunity that comes during a crisis.

• International Journal of Computer Science & Network Security
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• v.22 no.12
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• pp.116-124
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• 2022

Information and communication technologies used in the social sphere are born due to the development of computer technologies. The main task of the distance learning process in higher education institutions is not to provide information, but to teach how to obtain and use it. The purpose of the article: to identify innovative approaches in the training of specialists in higher education institutions in the context of distance learning. Various innovative approaches to organizing the work of students of higher educational institutions in the context of distance learning are considered. Based on the conducted research, it is concluded that each of the approaches described by us outlines the study of the phenomenon of professional training of a specialist in the condition of distance learning. All the described approaches significantly contribute to the improvement of professional training of specialists, encourage students to self-improvement, professional development and enrich their professional competence in modern conditions. The emergence and spread of innovative technologies means not only a change in the activity itself and its inherent means and mechanisms of its implementation, but also a significant restructuring of goals, value orientations, specific knowledge, skills and abilities. Therefore, the current stage of the development of civilization, scientific and technological progress requires the emergence of such specialists who would have broad humanitarian thinking, would have good psychological training, would be able to build professional activities according to laws that take into account the relationship between economic productivity and creativity, as well as the desire of the individual for constant renewal, self-realization. Only such qualities will help you master the specifics of innovative technologies well. We see the prospects in the study of innovative approaches to training specialists in higher education institutions in the condition of distance learning in foreign countries.

• English Language & Literature Teaching
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• v.17 no.2
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• pp.199-218
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• 2011

This study is to explore one of efficient procedures in producing English textbooks for secondary school students. According to a series of changes in the National Curriculum, new textbooks have been selected and used in English classes. Textbooks are one of the fundamental factors in teaching and learning languages together with learners and teachers. So this study emphasizes the significance of textbooks and presents the practical model of producing English textbooks including activity books, from major aspects such as planning, writing, editing, selecting, etc. The current government has made continuing efforts to improve English education development by administrating innovative policies [strategies]. However, there still remain lots of difficulties in this gigantic task, which is not an exception in the matter of textbooks. Therefore, to provide students with better textbooks, the government should not only invest great funds but also renovate the present polluted system of selecting textbooks.

• Applied Biological Chemistry
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• v.47 no.1
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• pp.149-153
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• 2004

전통된장 제조방법으로서 원료 혼합비, 메주의 건조시간 및 온도, 메주와 된장의 발효 시간 및 온도, 된장 간장의 분리 여부, 된장 숙성(aging) 시간을 조사하였다. 혈액응고 저해 활성(anticoagulant activity)을 fibrin clotting assay법으로 분석하여 혈액응고 저해활성과 제법간의 상관 관계를 검토하였다. 숙성 기간이 길수록 혈액응고 저해활성이 높게 나타나는 경향을 보였으나 선형적인 상관관계보다는 비선형적으로 양의 상관관계를 갖는 것으로 판단되었다. 이상의 결과를 토대로 혈액응고 저해활성이 높은 2종의 된장시료를 선발하였으며 숙성기간이 180일 이상일 경우 전통된장의 혈액응고 저해활성이 높은 것으로 판단되었다.