• Nuclear Engineering and Technology
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• 제55권8호
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• pp.2723-2733
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• 2023

Transuranic nuclides (such as ²³⁸Pu, ²⁵²Cf, ²⁴⁹Bk, etc.) have a wide range of application in industry, medicine, agriculture, and other fields. However, due to the complex conversion chain and remarkable fission losses in the process of transuranic nuclides production, the generation amounts are extremely low. High flux reactor with high neutron flux and flexible irradiation channels, is regarded as the promising candidate for producing transuranic nuclides. It is of great significance to increase the conversion ratio of transuranic nuclides, resulting in higher efficiency and better economy. In this paper, we perform an optimization design evaluation of producing transuranic nuclides in high flux reactor, which includes optimization design of irradiation target and influence study of reactor core loading. It is demonstrated that the production rate increases with appropriately determined target material and target structure. The target loading scheme in the irradiation channel also has a significant influence on the production of transuranic nuclides.

• Nuclear Engineering and Technology
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• 제56권1호
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• pp.147-159
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• 2024

Plutonium-238 has always been considered as the one of the promising radioisotopes for space nuclear power supply, which has long half-life, low radiation protection level, high power density, and stable fuel form at high temperatures. The industrial-scale production of ²³⁸Pu mainly depends on irradiating solid ²³⁷NpO₂ target in high flux reactors, however the production process faces problems such as large fission loss and high requirements for product quality control. In this paper, a conceptual design study of producing ²³⁸Pu in a multi-purpose high flux reactor was evaluated and analyzed, which includes a sensitivity analysis on ²³⁸Pu production and a further study on the irradiation scheme. It demonstrated that the target structure and its location in the reactor, as well as the operation scheme has an impact on ²³⁸Pu amount and product quality. Furthermore, the production efficiency could be improved by optimizing target material concentration, target locations in the core and reflector. This work provides technical support for irradiation production of ²³⁸Pu in high flux reactors.

• Nuclear Engineering and Technology
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• 제56권5호
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• pp.1679-1686
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• 2024

Graphite material plays an important role in nuclear reactors especially the high-temperature gas-cooled reactors (HTGRs) by its outstanding comprehensive nuclear properties. The structural integrity of graphite pebble fuel elements is the first barrier to core safety under any circumstances. The correct knowledge of the stiffness coefficient of the graphite pebble fuel element inside the reactor's core is significant to ensure the valid design and inherent safety. In this research, a vertical extrusion device was set up to measure the stiffness coefficient of the graphite pebble fuel element by the Institute of Nuclear and New Energy Technology (INET) of Tsinghua University in China. The stiffness coefficient equations of graphite pebble fuel elements at different temperatures are given (in a helium atmosphere). The result first provides the data on the high-temperature stiffness coefficient of pebbles in helium gas. The result will be helpful for the engineering safety analysis of pebble-bed nuclear reactors.

• Journal of Animal Science and Technology
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• 제63권4호
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• pp.934-953
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• 2021

Ciglitazone is a member of the thiazolidinedione family, and specifically binds to peroxisome proliferator-activated receptor-γ (PPARγ), thereby promoting adipocyte differentiation. We hypothesized that ciglitazone as a PPARγ ligand in the absence of an adipocyte differentiation cocktail would increase adiponectin and adipogenic gene expression in bovine satellite cells (BSC). Muscle-derived BSCs were isolated from six, 18-month-old Yanbian Yellow Cattle. The BSC were cultured for 96 h in differentiation medium containing 5 µM ciglitazone (CL), 10 µM ciglitazone (CM), or 20 µM ciglitazone (CH). Control (CON) BSC were cultured only in a differentiation medium (containing 2% horse serum). The presence of myogenin, desmin, and paired box 7 (Pax7) proteins was confirmed in the BSC by immunofluorescence staining. The CL, CM, and CH treatments produced higher concentrations of triacylglycerol and lipid droplet accumulation in myotubes than those of the CON treatment. Ciglitazone treatments significantly increased the relative expression of PPARγ, CCAAT/enhancer-binding protein alpha (C/EBPα), C/EBPβ, fatty acid synthase, stearoyl-CoA desaturase, and perilipin 2. Ciglitazone treatments increased gene expression of Pax3 and Pax7 and decreased expression of myogenic differentiation-1, myogenin, myogenic regulatory factor-5, and myogenin-4 (p < 0.01). Adiponectin concentration caused by ciglitazone treatments was significantly greater than CON (p < 0.01). RNA sequencing showed that 281 differentially expressed genes (DEGs) were found in the treatments of ciglitazone. DEGs gene ontology (GO) analysis showed that the top 10 GO enrichment significantly changed the biological processes such as protein trimerization, negative regulation of cell proliferation, adipocytes differentiation, and cellular response to external stimulus. Kyoto Encyclopedia of Genes and Genomes pathway analysis showed that DEGs were involved in the p53 signaling pathway, PPAR signaling pathway, biosynthesis of amino acids, tumor necrosis factor signaling pathway, non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, and Wnt signaling pathway. These results indicate that ciglitazone acts as PPARγ agonist, effectively increases the adiponectin concentration and adipogenic gene expression, and stimulates the conversion of BSC to adipocyte-like cells in the absence of adipocyte differentiation cocktail.

• 대한안전경영과학회지
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• 제19권2호
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• pp.135-146
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• 2017

The purpose of this study is to review the relationship between managerial system and incremental innovation, and the mediating effect of knowledge transfer in small business. In order to verify and achieve the purposes mentioned above, questionnaire data were gathered and analysed from 255 enterprise managers in western Kangwon-do province. Empirical survey's findings are as follows; First, CEO's support and education/training appeared to be positively related with knowledge transfer. Second, managerial system and knowledge transfer appeared to be positively related with incremental innovation. Third, knowledge transfer had mediating effect on the relationships of CEO's support-incremental innovation and education/training-incremental innovation.

• 한국경영과학회지
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• 제41권4호
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• pp.75-93
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• 2016

This study aims at analyzing the relationship between team characteristic and innovation performance. The mediating effect of creative climate on the team characteristic and innovation performance is also measured. Based upon literature review, individual creative characteristics, team diversity, team cohesion, task characteristics are presented as antecedents of team characteristic. Creative climate affects the creative behavior and innovative performance. Creative climate is measured as the Team Climate Inventory (TCI) proposed by Anderson & West (1998) including goal, participative-autonomy and innovative-support. Data were collected from 186 survey responses (54 Teams) out of total 462 (69 teams) from the R&D department of a major ICT firm in Korea. Empirical results show the diversity, cohesion, job characteristic, individual creative characteristic have a positive effect on the creative climate and innovation performance. The participative-autonomy climate factor appears to mediate the relationship between team characteristic (diversity, cohesion, job and individual characteristics) and innovation performance. However, the mediating effects of goals and innovative-support factors were not significant statistically. It was confirmed that the organization can contribute to improve the team innovation performance by facilitating a autonomy and participative climate as well as fostering the team characteristic.

• 벤처창업연구
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• 제10권1호
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• pp.55-67
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• 2015

본 연구는 최근 교육시장의 벤처기업이나 사내 벤처를 위한 혁신기술로 부상하고 있는 스마트러닝(Smart Learning)의 혁신저항에 대하여 연구하였다. 스마트러닝 학습 방법에 대한 지각된 혁신 특성의 상대적 이점, 복잡성 및 적합성이 혁신저항에 유의한 영향을 미치는지 알아보았다. 이어서 기존 학습법에 대한 태도와 지각된 자기효능이 혁신저항에 유의한 영향을 미치는지 알아보았다. 그리고 이용자의 이러한 혁신저항이 향후 이용에 영향을 미치는지 알아보았고, 인구통계에 따라 조절효과가 나타나는지 살펴보았다. 구조방정식 모형을 사용하여 분석한 결과, 상대적 이점만을 제외한 모든 요인이 혁신저항에 영향을 주는 것으로 나타났다. 이를 통해 혁신저항 역시 향후 이용의도에 유의한 영향을 미친다는 결과를 얻을 수 있었다.

• 한국수학교육학회지시리즈A:수학교육
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• 제55권4호
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• pp.417-445
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• 2016

The purpose of this research is to discover and analyze the stages of concern, level of use, innovation configurations and the analysis of their relationship to each other of storytelling-based math education among elementary teachers based on the concerns-based adoption model (CBAM). And then the researcher derives support strategies for the education by empirically examining at which levels and how actual elementary teachers perceive storytelling-based math education and also how they adopt it. In addition, the researcher lays the purpose of this study on seeking proper supporting strategies for helping elementary teachers implement storytelling-based math education and providing basic material for teaching activities by examining the correlation between stages of concern, levels of use and the innovation configuration, and grasping the relation between teachers concern and their educational practice regarding storytelling-based math education.

• International Journal of Computer Science & Network Security
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• 제21권9호
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• pp.173-178
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• 2021

The article reveals the essence of the concept of "pedagogical innovation" and identifies trends in the development of a modern educational institution. A qualitative analysis of the scientific literature in the field of innovation science has been carried out. The essence of the concept of "pedagogical innovation" is revealed. The modern classification of pedagogical innovations is given. The factors of the success of the introduction of pedagogical innovations are determined. The main trends in the development of modern educational institutions are outlined.

• International Journal of Computer Science & Network Security
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• 제22권6호
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• pp.382-389
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• 2022

The article is devoted to the research and search for effective pedagogical technologies. The definitions of "innovation", "technologicalization", "pedagogical technology" are analyzed. "Innovative pedagogical technology". The blocks that make up the innovative processes in education are studied. The importance and role of innovations in education (vocational education) are clarified. The components of pedagogical technology are studied: conceptual, content-procedural and professional. The signs of classifications of pedagogical technologies are investigated. The stages of evolution of the definition of "pedagogical technology", as well as the levels of its application in pedagogical science are highlighted. Criteria of manufacturability and signs of pedagogical technology are investigated.The algorithm for the analysis of pedagogical technology is investigated: identification of technology; name of technology; conceptual principles; the content of education; activity characteristics; organizational and methodological support of the educational process. Pedagogical technologies that should be implemented in vocational education institutions are analyzed.