• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.6
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• pp.1557-1562
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• 2005

A mechanism of hair cell damage caused by noise and ototoxic agents is mediated through generation of free radicals and reactive oxygen species (ROS). It is known that most of animals have defense systems to protect against ROS, and the cochlea of inner ear in animals also has ROS defense systems including several antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX), glutathione reductase (GR), and glutathione (GSH), which efficiently detoxifying ROS generated under normal condition. Steamed roots of Rehmannia glutinosa have been traditionally used in Oriental medicine for the treatment of auditory disease such as tinnitus, vertigo, and hearing loss as well as inflammatory diseases, hectic fever, night sweat, and headache. In the present study, we showed that the ethanol extract from steamed roots of R. giutinosa (ESRG) increased the antioxidant enzymes such as SOD, CAT, GPX, and GR activities and GSH level in HEI-OC1 auditory cells. This extract itself did not show any significant cytotoxicity up to $50{\mu}g/ml$. Our results further support the view that ESRG is promising sources of potential antioxidants. Future studies will be aimed at investigating the effects of ESRG on the regulation of cellular mechanisms and isolating and identifying the substances responsible for the regulation of antioxidant enzyme system from the plant extracts.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.33 no.3
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• pp.95-102
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• 2015

This study conducted the survey on the resources of traditional villages based on AHP in the subjects with the specialists in Korea and China to seek the resource evaluation standards to apply the preservation and development of traditional villages, and the differences of the importance on the resources among the specialists in both countries. We classified three levels of evaluation items to aim the deductions of the importance and priority in the resources of traditional villages. Upon the analysis results, natural resources were important in the level 1; environmental, historical, facility resources were important in the level 2; and the factors such as air, topography, traditional houses, agricultural landscape, shared community facilities, interchanges between urban and rural areas, family activities, and so on were important in the level 3. The factors that both Korean and Chinese groups evaluated as the most important ones were the same. In terms of overall importance by evaluation items, the factors such as air, water quality, noise, traditional houses, topography, shared community facilities, and so on were rated as relatively important in both Korean and Chinese groups. That is, the traditional villages have the necessity to preserve the cultural resources like their duties, however, it is required to control the natural environment with good quality preferentially. This study results can compare the importance on the resources of traditional village between Korea and China. Moreover, with calculation of the priority and scores for the preservation and management of traditional villages, they are expected to be used as the tool to apply the quantitative data in the evaluation process of traditional village resources in both countries.

• Journal of the Korean Society for Nondestructive Testing
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• v.24 no.1
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• pp.15-21
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• 2004

It is possible to detect flaws in pipelines without interruption using all EMAT transducer because it is a non-contact transducer which can transmit ultrasonic waves into specimens without couplant. And it ran easily generate guided waves desired in each specific problem by altering the design of coil and magnet. In the present work, EMAT systems have been fabricated to generate surface waves, and selectively the plate wave of $A_1\;or\;S_1$ mode. The surface wave of 1.5MHz showed a good signal-to-noise ratio without distortion in its propagation along a pipeline, while the $S_1$ mode of 800kHz and the $A_1$ mode of 940kHz were distorted according to their dispersive properties. The wider the excitation pulse becomes, the better the mode selectivity of the plate waves becomes. A pipe of 256mm inner diameter and 5.5m thickness with 5 flaws was used for comparing the flaw detectability among the modes under consideration.

• Journal of the Korean Society of Radiology
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• v.5 no.2
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• pp.59-66
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• 2011

There is a difficulty because of classifying the anatomical structure in the neck CT scan by the beam hardening artifact no more than disease and it including the 6, 7 number cervical spine and intervertebral disk. In case of enforcing the neck CT scan cause of the inner diameter of beam artifact tried to be inquired by the image evaluation according to the change of the image evaluation according to the direction of the shoulder joint applying the variation method of a posture and location and Kernel value and it was most appropriate, the lion tax and Kernel value try to be searched for through an experiment. Somatom Sensation 16 (Siemens, Enlarge, Germany) equipment was used in a patient 30 people coming to the hospital for the neck CT scan. A workstation used the AW 4.4 version (GE, USA). According to a direction and location of the shoulder joint, the patient posture gave a change to the direction of the shoulder joint as the group S it gave a change as three postures and placed the both arms comfortably and helps a group N and augmented unipolar left in the wealthy merchant and group P it memorized the both hands and ordered the eversion and drops below to the utmost and enforced a scan. By using a reconstructing method as the second opinion, it gave and reconstructed the Kernel value a change based on scan data with B 10 (very smooth), B 20 (smooth), B 30 (medium smooth), B 40 (medium), B 50 (medium sharp), B 60 (sharp), and B 70 (very sharp). By using image data which gave the change of the examination posture and change of the Kernel value and are obtained, we analyzed through the noise value measurement and image evaluation of. The outside wire eversion orders the both hands and the examination posture is cost in the neck CT scan with the group P it drops below to the utmost. And in case of when reconstructing with B 40 (medium) or B 50 (medium sharp) being most analyzed into the inappropriate posture and Kernel value and applying the Kernel value to a clinical, it is considered to be very useful.

• Progress in Medical Physics
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• v.22 no.1
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• pp.28-34
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• 2011

To perform the Adaptive Radiation Therapy (ART), a high degree of deformable registration accuracy is essential. The purpose of this study is to identify whether the change of MV CBCT intensity can improve registration accuracy using predefined modification level and filtering process. To obtain modification level, the cheese phantom images was acquired from both kilovoltage CT (kV CT), megavoltage cone-beam CT (MV CBCT). From the cheese phantom images, the modification level of MV CBCT was defined from the relationship between Hounsfield Units (HUs) of kV CT and MV CBCT images. 'Gaussian smoothing filter' was added to reduce the noise of the MV CBCT images. The intensity of MV CBCT image was changed to the intensity of the kV CT image to make the two images have the same intensity range as if they were obtained from the same modality. The demon deformable registration which was efficient and easy to perform the deformable registration was applied. The deformable lung phantom which was intentionally created in the laboratory to imitate the changes of the breathing period was acquired from kV CT and MV CBCT. And then the deformable lung phantom images were applied to the proposed method. As a result of deformable image registration, the similarity of the correlation coefficient was used for a quantitative evaluation of the result was increased by 6.07% in the cheese phantom, and 18% in the deformable lung phantom. For the additional evaluation of the registration of the deformable lung phantom, the centric coordinates of the mark which was inserted into the inner part of the phantom were measured to calculate the vector difference. The vector differences from the result were 2.23, 1.39 mm with/without modification of intensity of MV CBCT images, respectively. In summary, our method has quantitatively improved the accuracy of deformable registration and could be a useful solution to improve the image registration accuracy. A further study was also suggested in this paper.