• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2011.10a
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• pp.331-334
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• 2011

This is a study about a platform realization measuring the extent of reaction in nerve, as giving a electrical impulse on a nerve pulp regulating a function of muscle, about a measurement of nerve reaction in the amount of current, the lasting time of current, and the position of electrode from a electrical impuls.The position of an electrode in a electrical nerve impuls have nothing to do with all nerves from exercise to all things. There is the Single Twitch Stimulation(STS), Train-of-four(TOF), and Double Burst Stimulation(DBS) in the form of nerve stimulation. This report is needed for selecting MCU of low electric power for a base in embedded system and measuring the extent of reaction after making a sensor interface to know sensitivity of measuring sensor in basic reaction of nerve impuls. The platform is realized to select a high efficiency AD Convertor for raising accuracy in measured data. As the platform in this report was developed for a medical appliances, it was designed to consider user safety in electric power Isolation when making electric power circuit.

• Journal of Pharmacopuncture
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• v.14 no.1
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• pp.5-24
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• 2011

Objective: This study was performed to analyse four weeks repeated -dose toxicity of Sweet Bee Venom (SBV-pure melittin, the major component of honey bee venom) in rats. Methods: All experiments were conducted under the regulations of Good Laboratory Practice (GLP) at Biotoxtech Company, a non-clinical study authorized institution. Male and female rats of 5 weeks old were chosen for the pilot study of four weeks repeated-dose toxicity and was injected at the level of 0.56 mg/kg body weight (eighty times higher than the clinical application dosage as the high dosage), followed by 0.28 and 0.14 mg/kg as midium and low dosage, respectively. Equal amount of normal saline was injected as the control group every day for four weeks. Results: 1. No mortality was witnessed in all of the experiment groups. 2. All experiment groups appealed pain sense in the treating time compared to the control group, and side effects such as hyperemia and movement disorder were observed around the area of injection in all experiment groups, and the higher dosage in treatment, the higher occurrence in side effects. 3. Concerning weight measurement, neither male nor female groups showed significant changes compared to the control group. 4. Concerning to the CBC and biochemistry, all experiment groups didn't show any significant changes compared to the control group. 5. Concerning weight measurement of organs, experiment groups didn't show any significant changes compared to the control group. 6. To verify abnormalities of organs and tissues, those such as cerebellum, cerebrum, liver, lung, kidney, and spinal cords were removed and we conducted histologocal observation with H-E staining. Concerning the histologocal observation of liver tissues, some fatty changes were observed around portal vein in 0.56 mg/kg experiment group. But another organs were not detected in any abnormalities. 7. The proper high dosage of SBV for the thirteen weeks repeated test in rats may be 0.28 mg/kg in one time. Conclusion: Above findings suggest that SBV is relatively safe treatment medium. Further studies on the subject should be conducted to yield more concrete evidences.

• Journal of Sensor Science and Technology
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• v.24 no.2
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• pp.113-118
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• 2015

Intravenous (IV) infusion set is one of the most common treatment methods applied to hospitalized patients. However, it is necessary to check the injection of IV solution in order to prevent patients from any possible medical injuries. In this paper, using the optical sensors to detect exhaustion of IV solution was proposed. The optical sensor is coplanar structure composed of LED and photodiode which is installed according to focal distance of the lens. These two elements detect exhaustion of IV solution at the desired point conveniently. Through the results of experiments using various wavelength of LED (R.G.B), the blue LED was selected to the optimum light source. The suggested optical sensor can detect exhaustion of IV solution by the differences in the amount of light which is caused by properties such as total reflection, refractive index and scattering. From the implementation, the detector is applicable to both containers of IV solution, glass bottle and plastic pack. And also the result shows apparent differences according to existence of IV solution even if the IV solution color and illumination were changed.

• Journal of the Korea Institute of Military Science and Technology
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• v.20 no.4
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• pp.587-596
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• 2017

In this study, multi-chambered single autoinjector(2in1) and KMARK-1 containing atropine and 2-PAM(pyridine-2-aldoxime methylchloride) were administered to the beagle's muscle, and blood samples were taken for a certain period of time to compare and evaluate the pharmacokinetic profiles of the two drugs. Male beagles were used and classified into two test groups(G1, G2), and crossover pharmacokinetic studies were performed in two test groups. Blood samples were collected from the jugular vein for analysis after administration. The 90 % confidence interval(CI) for log transformed data indicated that the Cmax for both atropine(log 0.9683 ~ log 1.113) and 2-PAM(log 0.9453 ~ log 1.214) was within the limits of bioequivalence criteria, but the AUC for atropine(log 1.1786 ~ log 1.3238) failed to meet this criteria. This is expected as the amount of atropine dose is 25 % higher for the test as compared to the reference formulation. In summary, in view of the ATNAA(antidote for nerve agent of US) authorization, the Cmax equivalence was more important than AUC equivalence, so in this study, we also focused on verifying the equality of Cmax between the two autoinjectors.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.5
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• pp.3627-3632
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• 2015

We investigated mechanical, rheological and electrical properties of graphite/PP/LCP composites for a bipolar plate of the polymer electrolyte membrane fuel cell. The composites containing very low molecular weighted PP showed much higher electrical conductivity compared with other thermoplastics. This was attributed to the enhanced dispersion of graphite particles due to the low viscosity of the PP. The conductivity of the composites was increased in a great extent by incorporation of small amount of carbon nano tube (CNT). However, the acid treated CNT which contains oxygen atoms did not increase the conductivity of the composite. From this result, it is concluded that the CNT has higher affinity with non polar polymer. The composite with low molecular weighted PP provided good processability so that the composites can be processed by an injection molding while the mechanical strength is deficient compared to other polymers. In order to reinforce the low mechanical property, LCP/PP was used as a binder and the graphite/PP/LCP composite showed the higher conductivity and moderate mechanical strength maintaining suitable processability.

• Restorative Dentistry and Endodontics
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• v.40 no.2
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• pp.155-160
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• 2015

Objectives: Achieving adequate anesthesia with inferior alveolar nerve blocks (IANB) is of great importance during dental procedures. The aim of the present study was to assess the success rate of two anesthetic agents (bupivacaine and lidocaine) for IANB when treating teeth with irreversible pulpitis. Materials and Methods: Sixty volunteer male and female patients who required root canal treatment of a mandibular molar due to caries participated in the present study. The inclusion criteria included prolonged pain to thermal stimulus but no spontaneous pain. The patients were randomly allocated to receive either 2% lidocaine with 1:80,000 epinephrine or 0.5% bupivacaine with 1:200,000 epinephrine as an IANB injection. The sensitivity of the teeth to a cold test as well as the amount of pain during access cavity preparation and root canal instrumentation were recorded. Results were statistically analyzed with the Chi-Square and Fischer's exact tests. Results: At the final step, fifty-nine patients were included in the study. The success rate for bupivacaine and lidocaine groups were 20.0% and 24.1%, respectively. There was no significant difference between the two groups at any stage of the treatment procedure. Conclusions: There was no difference in success rates of anesthesia when bupivacaine and lidocaine were used for IANB injections to treat mandibular molar teeth with irreversible pulpitis. Neither agent was able to completely anesthetize the teeth effectively. Therefore, practitioners should be prepared to administer supplemental anesthesia to overcome pain during root canal treatment.

• Journal of the Korean Institute of Gas
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• v.19 no.6
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• pp.34-39
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• 2015

Recently, most of the energy consumed in vehicle is derived from fossil fuels. For this reason, the demand for clean, renewable and affordable alternative energy is forcing the automotive industry to look beyond the conventional fossil fuels. Natural gas represents today a promising alternative to conventional fuels for vehicles propulsion, because it is characterized by a relatively low cost, better geopolitical distribution than oil, lower environmental impact, higher octane number and a higher self ignition temperature. Above all, CNG is an environmentally clean alternative to the existing spark ignition engines with the advantages of minimum change. In this study was installed bi-fuel system that a conventional 2 liters gasoline engine was modified to run on natural gas by a gas injection system. Experiments were mainly carried on the optimization of an ECU control strategy affecting the emission characteristics of CNG/Gasoline bi-fule vehicle. The test results shown that CO2 emission in bi-fuel mode was reduced 16% compared to gasoline fuel in the NEDC mode. Also the amount of CO and HC emissions in bi-fuel and gasoline modes were found to equality. But Compared to gasoline, the bi-fuel mode resulted in higher NOx emissions.

• Journal of Korean Society on Water Environment
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• v.22 no.3
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• pp.521-526
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• 2006

We have studied the possibility of removing Anabaena macrospora by injecting copper sulfate ($CuSO_4{\cdot}5H_2O$) into the raw water of a drinking water purification plant. Anabaena macrospora caused the unpleasant geosmin odor of drinking water in August 2001. The cell break-point of A. macrospora was 0.3 mg/L of $CuSO_4$. We were able to reduce the standing crops of A. macrospora effectively because $CuSO_4$ could break A. macrospora selectively. Because 0.3 mg/L of $CuSO_4$ could break both cells and akinetes, it reduced the possibility of a recurrent problem for them to meet a favorable condition. When $CuSO_4$ was injected in the early growth phase of algae and the mixing intensity was high, A. macrospora could be removed most effectively. The odor caused by A. macrospora was sustained for a while without any sudden change of environmental condition. Therefore, we hope that it could shorten the period of obstacle by injecting the optimal amount of 0.3 mg/L of $CuSO_4$. The water quality, alkalinity, conductivity, hardness and pH didn't changed by the injection of $CuSO_4$.

• Korean Journal of Veterinary Research
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• v.35 no.3
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• pp.471-480
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• 1995

The purpose of this experiment was to develop a simple and reliable HPLC method for the detection of ciprofloxacin in chicken serum and to provide a basic data on pharmacokinetic parameters after oral and intramuscular administration. The results obtained were as follows: 1. 0.2% meta-phosphoric acid: acetonitrile(7:3, v/v) solution had a high and regular recovery rates and was selected as an extraction solution. 2. The recovery rates of ciprofloxacin were 83-97% with the selected solution in chicken serum and the detection limit was 50ng/ml in serum. 3. Ka(abosorption rate constant) were 3.652 1/h in fasted group and 0.880 1/h in non-fasted group, and Ke (elimination rate constant) were 0.061 1/h and 0.133 1/h, respectively. 4. The highest concentration in serum after intramuscular injection was 840ng/ml within 15-30min and 160-324ng/ml in 1.1-3.2 hours after oral administration. 5. The time course of blood concentration fits well into a 2 compartment model. 6. On oral administration of ciprofloxacin with feed, ciprofloxacin was absorbed more slowly and the amount of absorbed was smaller than that of in fasted chickens. 7. Blood concentration of ciprofloxacin increased in a dose-dependent manner after intramusclular and oral administraiton.

• Resources Recycling
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• v.17 no.1
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• pp.66-72
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• 2008

Fundamental studies for the synthesis of Mn-Zn ferrite powder were investigated using a series of leaching and coprecipitation processes from spent alkaline manganese batteries. Zinc and Manganese dissolution rates obtained at the reaction conditions of 100g/L pulp density, 3.0M $H_2SO_4$, $60^{\circ}C$ and 200 rpm with 30 ml $H_2O_2$ as a reducing agent were more than 97.9% and 93.9% and coprecipitation of Mn-Zn ferrite powder was performed according to various reaction conditions such as temperature, time and amount of $O_2$ gas injection using the leaching solution. As a result of coprecipitation, Mn-Zn ferrite could be synthesized directly at low temperature in the reaction condition pH 12, $80^{\circ}C$, $O_2$ 1.3 L/min. and 400 rpm. The synthesized Mn-Zn ferrite powder was spherical powder of $0.143{\mu}m$ particle size and had a saturation magnetization about 80 emu/g.