• Proceedings of the Korean Environmental Sciences Society Conference
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• 2003.11a
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• pp.27-32
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• 2003

Atmospheric and oceanic numerical models are usually initial-value and/or boundary-value problems. Change in either initial or boundary conditions leads to a variation of model solutions. Much of the predictability research has been done on the response of model behavior to an initial value perturbation. Less effort has been made on the response of model behavior to a boundary value perturbation. In this study, we use the latest version of the National Center for Atmospheric Research (NCAR) Community Climate Model (CCM3) to study the model uncertainty to tiny SST errors. The results show the urgency to investigate the second kind predictability problem for the climate models.

• Tuberculosis and Respiratory Diseases
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• v.71 no.4
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• pp.286-290
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• 2011

Although failure of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKI) is generally believed to be associated with cross-resistance to other EGFR TKI, the benefit of administering erlotinib as a second EGFR TKI after resistance of gefitinib as the first TKI has been well known. However, good response to gefitinib after an initial response to erlotinib has been rare. We report that a 45-year-old woman (never smoked), with lung adenocarcinoma and EGFR mutation, showed an initial response to erlotinib, and then responded to gefitinib again.

• Journal of the Earthquake Engineering Society of Korea
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• v.26 no.2
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• pp.95-103
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• 2022

In order to evaluate the earthquake safety of equipment in structures, it is essential to analyze the In-Structure Response Spectrum (ISRS). The ISRS has a peak value at the frequency corresponding to the structural vibration mode, but the frequency and amplitude at the peak can vary because of many uncertain parameters. There are several seismic design criteria for ISRS peak-broadening for fixed base structures. However, there are no suggested criteria for constructing the design ISRS of seismically isolated structures. The ISRS of isolated structures may change due to the major uncertainty parameter of the isolator, which is the shear stiffness of the isolator and the several uncertainty parameters caused by the nonlinear behavior of isolators. This study evaluated the effects on the ISRS due to the initial stiffness of the bi-linear curve of isolators and the variation of effective stiffness by the input ground motion intensity and intense motion duration. Analyzing a simplified structural model for isolated base structure confirmed that the ISRS at the frequency of structural mode was amplified and shifted. It was found that the uncertainty of the initial stiffness of isolators significantly affects the shape of ISRS. The variation caused by the intensity and duration of input ground motions was also evaluated. These results suggested several considerations for generating ISRS for seismically isolated structures.

• Composites Research
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• v.22 no.1
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• pp.1-8
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• 2009

In this paper low-velocity impact response and damage of composite laminates is analytically investigated. A modified displacement field of plate considering initially loaded in-plane strain is proposed. From the displacement field a finite element equation on structural behavior of composite laminate is newly induced and a computational program is coded. Numerical results using the FEM code is compared with the numerical ones from reference. Additional numerical analysis is performed on another impact condition and effect of initial in-plane load is reviewed. Potential delamination damage area in the first inter-ply surface from bottom of laminate is approximated and effect of initial in-plane load and impact condition is also reviewed.

• Journal of The Korean Society of Agricultural Engineers
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• v.46 no.2
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• pp.67-75
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• 2004

This study aims to investigate the dynamic behaviour of a parabolic arch with initial deflection by using the elasto-plastic finite element model where the von-Mises yield criteria have been adopted. The initial deflection of arch was assumed by the high order polynomial of ${\omega}_i$ = ${\omega}_o$${(1-{(2x/L)}^m)}^n$) and the sinusoidal profile of ${\omega}_i$ = ${\omega}_o$$\sin$(n$\pi$x/L). Several numerical examples were tested considering symmetric initial deflection modes when the maximum initial deflection of an arch is fixed as L/500, L/1000, L/2000 or L/5000. The effects of polynomials order on the dynamic behavior of arch were not conspicuous. The most unfavorite dynamic response occurs when the maximum initial deflection varies from L/1000 to L/4000 if the initial deflection mode is represented by high order polynomials.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2002.05a
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• pp.225-228
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• 2002

When the fuzzy logic controller (FLC), which is designed based on the plant model, is applied to the real control system, satisfactory control performance may not be attained due to modeling errors from the plant model. In such cases, the control parameters of the controller must be adjusted to enhance control performance. Until now, the trial and error method has been used, consuming much time and effort. To resolve such problem, response surface methodology (RSM), a new method of adjusting the control parameters of the controller, is suggested. This method is more systematic than the previous trial and error method, and thus optimal solutions can be provided with less tuning. First, the initial values of the control parameters were determined through the plant model and the optimization algorithm. Then, designed experiments were performed in the region around the initial values, determining the optimal values of the control parameters which satisfy both the rise time and overshoot simultaneously.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10b
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• pp.195-198
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• 1996

The control objective of drum level of boiler in thermal power plant is to maintain drum level at constant setpoint regardless of disturbance such as main steam flow. The initial response of the drum level loop process is in a direction opposite to the final response. The drum level loop shows inverse response when the power is changed abruptly. We adopt fuzzy controller using knowledge base considering system dynamics for controlling drum level. Finally, the simulation result using the digital simulator for boiler system in Seoul Power Plant Unit 4 shows the validity of fuzzy controller.

• Journal of the korean academy of Pediatric Dentistry
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• v.6 no.1
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• pp.35-41
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• 1979

Of 42 children, 21 in male and 21 in female, whose ages ranged from 2 to 5 years old, the response of young children to their initial series of dental visits was examined. The results were as follows; 1. With continued experience, the child's response improved, indicating desensitization to dental stress. 2. Experience may reduce the general amount of negative response by allowing the child to accurately distinguish between stressful and non-stressful procedures.

• Geomechanics and Engineering
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• v.31 no.3
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• pp.329-337
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• 2022

In this paper, the thermal post-buckling characteristics of functionally graded (FG) pipes with initial geometric imperfection are studied. Considering the influence of initial geometric defects, temperature and geometric nonlinearity, Euler-Lagrange principle is used to derive the nonlinear governing equations of the FG pipes. Considering three different boundary conditions, the two-step perturbation method is used to solve the nonlinear governing equations, and the expressions of thermal post-buckling responses are also obtained. Finally, the correctness of this paper is verified by numerical analyses, and the effects of initial geometric defects, functional graded index, elastic foundation, porosity, thickness of pipe and boundary conditions on thermal post-buckling response are analyzed. It is found that, bifurcation buckling exists for the pipes without initial geometric imperfection. In contrast, there is no bifurcation buckling phenomenon for the pipes with initial geometric imperfection. Meanwhile, the elastic stiffness can significantly improve thermal post-buckling load and thermal post-buckling strength. The larger the porosity, the greater the thermal buckling load and the thermal buckling strength.

• Food Science and Biotechnology
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• v.18 no.4
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• pp.939-947
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• 2009

In order to produce vinegar using onions, 12 acetic acid bacteria were screened from the juice of fallen peaches, and a strain showing the highest acetic acid productivity among them was selected and identified as Acetobacter tropicalis No. 22. The culture broth containing 2.5%(w/v) of initial sugar concentration showed maximum acetic production after 10 days of cultivation, and the acetic acid was produced at the highest rate and reached the maximum acidity after 2 to 6 days of cultivation when the residual sugar and the ethanol concentration were in the range of 1.6 to 2%(w/v) and 0.6 to 1.8%(v/v), respectively. Also optimum conditions for acetic acid production by response surface method using the fractional factorial design with 3 variables and 5 levels were involved with initial ethanol content of 4.67%(v/v), initial acidity of 0.03%, and initial glucose concentration of 2.35%(w/v) and predicted level of acetic acid production at these conditions was 3.77%.