• Journal of Pharmaceutical Investigation
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• v.39 no.6
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• pp.393-400
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• 2009

PHEA (hydroxyethyl-aspartamide)-mPEG (methoy-polyethyleneglycol)-$C_{16}$ (hexadecylamine)-ED (ethylenediamine) was prepared as a drug delivery carrier. The structure and molecular weight of polymers were characterized by $^1H$-NMR and gel permeation chromatography. Micelle size and shape were measured by electro-photometer light scattering and transmission electron microscope. The mean diameter of micelles was 23 nm in aqueous solution. To evaluate the potential of these polymeric micelles as a drug carrier, PSI-mPEG-$C_{16}$-ED was conjugated with Cy5.5 for Near-Infrared Fluorescent (NIRF) based optical imaging. PSI-mPEG-$C_{16}$-ED-Cy5.5 was injected intravenously into mice (n=5) and in vivo NIRF imaging was performed during 48 h after injection. The biodistribution study at 24 h after injection showed the longcirculation property of PSI-mPEG-$C_{16}$-ED-Cy5.5. Therefore, PSI-mPEG-$C_{16}$-ED micelles could be a promising drug carrier and imaging agent.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.11 no.1
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• pp.23-39
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• 1998

The clinical data and thermographic imaging were analyzed on the 100 cases of Bell's palsy who were treated in the Kwang-Ju Oriental Medical Hospita! of Wonkwang University from February to October 1997. All the cases were taken Digital Infrared Thermograph Imaging(DITI) before treatment and 30 cases of them were taken follow up imaging again after recovery. And the following results were obtained. 1. Of 100 cases, under teenager occupied $1\%,\;teenager\;8\%,\;2nd\;decade\;14\%,\;3rd\;decade\;11\%,\;4th\;decade\;16\%,\;5th\;decade\;26\%,\;6th\;decade\;16\%,\;7th\;decade\;7\%\;and\;over\;80\;occupied\;1\%$. 2. Male occupied $48\%$ and female occupied $52\%$. 3. $42\%\;of\;male\;and\;23\%$ of female had the affected side at left side. And right facial nerve palsy occured at $29\%\;of\;male\;and\;29\%$ of female. 4. The most common cause of Bell's palsy was cold wind $18\%$, and the next were excessive labor $15\%,\;stress\;12\%,drinking\;2\%\;and\;cold\;food\;1\%$. 5. Thermal pattern were present as hyperthermal pattern in $44\%$ and hypothermal pattern in $22\%$. 6. The DITI showed hyperthermal pattern as close as to the onset day and changes to hypothermal pattern as times passed. 7. The DITI pattern and post-auricular pain, the most common prodomal syndrome, showed no significant relationship. 8. The relationship between the grade of paralysis and thermal patttern of DITI showed no significance. 9. Mean temperature of loci in affected side indicrtted $30.27^{\circ}C\;at\;Yang\;baek,\;30.02^{\circ}C\;at\;Taeyang,\;29.25^{\circ}C\;at\;Geoyo,\;29.62^{\circ}C\;at\;Jichang,\;29.78^{\circ}C\;at\;Hakwan,\;29.61^{\circ}C\;at\;Hyupgeo,\;and\;30.59^{\circ}C$at Yeopoong. 10. Mean temperature of loci in unaffected side showed $30.16^{\circ}C\;at\;Yang\;baek,\;30.02^{\circ}C\;at\;Taeyang,\;29.61^{\circ}C\;at\;Geoyo,\;29.68^{\circ}C\;at\;Jichang,\;29.70^{\circ}C\;at\;Hakwan,\;29.57^{\circ}C\;at\;Hyupgeo,\;and\;29.89^{\circ}C$at Yeopoong. 11. Of 30 cases who were taken follow up imaging again after recovery, the relationship between delta T at loci and symptoms showed no significance. It should be needed further investigation in order to apply them for clinical evaluation.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.68.1-68.1
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• 2013

Infrared Medium-Deep Survey is a near-infrared imaging survey geared toward understanding the formation and the evolution of quasars and galaxies at high redshift, and studying transient and time-variable objects such as gamma-ray bursts, supernovae, and young stellar objects. The survey uses a multi-tier structure, with deep imaging survey of 100 $deg^2$ using UKIRT to the depth of 23 AB mag, and a shallower imaging of interesting sources using the CQUEAN camera on the 2.1m telescope at McDonald observatory. This talk will give an overview of the survey strategy, the instrument development, and science highlights. The science highlights will include the discovery of high redshift quasars, high redshift galaxy clusters, GRBs, and other interesting sources. At the end of the talk, we will also present the future prospects of our study.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.7
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• pp.1653-1660
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• 2010

In this study, change of body surface temperature was measured using Digital Infrared Thermographic Imaging(DITI) to check muscle fatigue recovery & muscle pain control by magnetic stimulations. For clinical trials, subjects were divided into 3 groups : non stimulation group(NSG), electrical stimulation group(ESG) and micro magnetic stimulation group(MSG). In result, temperature differences between left and right arm surfaces were measured as much as $0.86{\pm}0.43^{\circ}C$(n=96) after the exercise, $0.78{\pm}0.12^{\circ}C$ after the electrical stimulation and $0.1{\pm}0.39^{\circ}C$ after the micro magnetic stimulation. Also after 3days, temperature differences between left and right arm surfaces were measured as much as $0.3{\pm}0.14^{\circ}C$ in the NSG, $0.05{\pm}0.21^{\circ}C$ in the ESG and $0.03{\pm}0.21^{\circ}C$ in the MSG. These data showed that the lowest temperature difference between left/right body surface was measured in MSG.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.5
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• pp.557-564
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• 2017

The purpose of the thermal imaging observation device mounted on the K's tank in the Republic of Korea military is to convert infrared rays into visual information to provide information about the environment under conditions of restricted visibility. Among the various performance indicators of thermal observation devices, such as the view, magnification, resolution, MTF, NETD, and Minimum Resolvable Temperature Difference (MRTD), the MRTD is the most important, because it can indicate both the spatial frequency and temperature resolvable. However, the standard method of measuring the MRTD in NATO contains many subjective factors. As the measurement result can vary depending on subjective factors such as the human eye, metal condition and measurement conditions, the MRTD obtained is not stable. In this study, these qualitative MRTD measurement systems are converted into quantitative indicators based on a gray scale using imaging processing. By converting the average of the gray scale differences of the black and white images into the MRTD, the mean values can be used to determine whether the performance requirements required by the defense specification are met. The (mean) value can also be used to discriminate between detection, recognition and identification and the detectable distance of the thermal equipment can be analyzed under various environmental conditions, such as altostratus, heavy rain and fog.

• The Journal of Internal Korean Medicine
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• v.21 no.1
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• pp.7-12
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• 2000

Objectives : This studies were performed to investigate the correlation between the treatment effects and the changes of the thermal differences at the pre and post-treatment by using the digital infrared computer thermographic imaging (D.I.T.I) to the irritable colon syndrome 30 patients. Methods : The extracts of the gwakhyangjunggisan were administerd to the patients by oral method three times per day during four weeks. we selected the Chung-Wan($CV_{12}$), Chunchu($S_{25}$). Hapkok($LI_4$), Naegwan($P_6$), Yongdo($H_4$) acupoints and treated the patients two times per week during four weeks. One week later, we investigated the changes of the pressure pain around left side Pokkyol($SP_{14}$), the symptoms. and the skin temperature changes on Pokkyol($SP_{14}$) and Kimun($LR_{14}$) around, by using the D.I.T.I. Results : In the correlation between the severity of the pressure pain around left side Pokkyol($SP_{14}$) and the thermal differences on Pokkyol($SP_{14}$) and Kimun($LR_{14}$) around, before the treatment, the more the pain was severe, the more the skin temperature was differential significantly. In the correlation between the severity of the symptoms and the thermal differences on Pokkyol($SP_{14}$) and Kimun($LR_{14}$) around, before the treatment, the more the symptom was severe, the more the skin temperature was differential significantly. In the changes of the pressure pain around left side of Pokkyol($SP_{14}$), the improved were significantly higher than the unimproved. In the changes of the symptoms, the improved were significantly higher than the unimproved. In the correlation between the changes of the pressure pain around left side Pokkyol($SP_{14}$) and the changes of the thermal differences at the pre and post- treatment, the more the pain was improved, the more the thermal change was widened significantly. In the correlation between the changes of the symptoms and the changes of thermal differences at the pre and post-treatment, the more the symptom was improved. the more the thermal change was widened significantly. Conclusions : Above the results, the treatments was effective and the digital infrared computer thermographic imaging (D.I.T.I) was useful to prove the improvements of the pressure pain and the symptom with the irritable bowel syndrome patients.

• Journal of Acupuncture Research
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• v.23 no.5
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• pp.219-228
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• 2006

Objectives : To observe the effect of acupuncture treatment on Digital Infrared Thermographic Imaging(DITI) in frozen shoulder patients. Methods : 17 voluntary patients received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The patients were instructed to practice self exercise during their daily lives. Evaluations were made before treatment, after 1 week of treatment, after 2 weeks, 3 weeks and after 4 weeks of treatment. Constant Shoulder Assessment(CSA), Shoulder Pain and Disability Index(SPADI), Range of Motion(ROM) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). DITI was measured before treatment and after 4weeks of treatment. The obtained data was analyzed. Results : CSA, SPADI, VAS, adduction and extension showed significant(p<0.05) improvement. Abduction and flexion both improved after 4 weeks of treatment, but the improvement was statistically insignificant(p>0.05). DITI showed improvement but the improvement was insignificant(p>0.05). Conclusion : 4 weeks of acupuncture treatment significantly improved CSA, SPADI, VAS, adduction and extension in frozen shoulder patients(p<0.05). The improvement of abduction and flexion after 4 weeks of acupuncture treatment was insignificant(p>0.05). DITI results improved after 4 weeks of acupuncture treatment. But the change of thermal difference was insignificant(p>0.05).

• Journal of the Korea Institute of Military Science and Technology
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• v.7 no.4 s.19
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• pp.79-86
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• 2004

This paper has presented to the design results of the analog and digital signal processor for the 2nd generation thermal imaging system using $480\times6$ infrared focal plane array In order to correct non-uniformities of detector arrays, we have developed the 2-point correction method using the thermo electric cooler. Additionally, to enhance the image of low contrast and improve the detection capability, we developed the new technique of histogram processing being suitable for the characteristics of contrast distribution of thermal imagery. Through these image processing techniques, we obtained a high qualify thermal image and acquired good result.

• Journal of the Korean Institute of Telematics and Electronics A
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• v.32A no.1
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• pp.193-199
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• 1995

A novel imaging method in which time-division spinning reticle samples different pixel location of input image in different time is presented. The lens collects the beam passing throughthe reticle to a photodetector. Image reconstruction is accomplished by sampling the detector output corresponding to the spinning speed of reticle. Since the time-division reticle system removed the necessity of bandpass filter bank which has sharp cut-off characteristic, high resolution image is obtained without increasing the number of filter. To confirm the validity of this method, a computer simulation and an optical experiment using visual light are presented.

• Journal of the Korea Institute of Military Science and Technology
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• v.7 no.3 s.18
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• pp.101-109
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• 2004

Image enhancement for Infrared imaging system is mainly based on the global histogram equalization. The global histogram equalization(GHE) is a method in which each pixel is equalized by using a whole histogram of an image. GHE is speedy and effective for real-time imaging system but its method fails to enhance the fine details. On the other hand, the basic local histogram equalization(LHE) method uses sliding a window and. the pixels under the window region are equalized over the whole output dynamic range. The LHE is adequate to enhance the fine details. But this method is computationally slow and noises are over-enhanced. So various local histogram equalization methods have been already presented to overcome these problems of LHE. In this paper, a new regional dynamic range histogram equalization (RDRHE) is presented. RDRHE improves the equalization quality while reducing the computational burden.