• 한국농공학회지
• /
• 제44권2호
• /
• pp.67-74
• /
• 2002

The purpose of this study was to investigate the effects of ponding depth treatment on water balance in paddy fields. Three ponding depth treatments, very shallow, shallow, and deep were used. The experimental plots were three 80m $\times$ 8m rectangular plots. Daily values of rainfall amount, ponding depth, irrigation water, drainage water, evapotranspiration, and infiltration were measured in the field. The ponding depth was continuously observed by water level logger during the growing season. The ET was measured by 1-m diameter PVC lysimeters. Irrigation water volume was measured by 75 mm pipe flowmeters and the drainage water volume by 75 mm pipe flowmeters and a recording Parshall flume. The results showed that irrigation water depths were 688.9 mm, 513.6 mm, and 624.4 mm in very shallow, shallow, and deep ponding, respectively. The effective rainfall amounts (effective ratio) were 243.7 mm(48.8%), 344.6 mm(68.9%), and 272.9 mm(54.6%) in very shallow, shallow, and deep ponding, respectively. The three treatments did not show any statistical difference in growth and yields. But the shallow depth treatment showed the largest yield.

• 임상이비인후과
• /
• 제29권2호
• /
• pp.301-306
• /
• 2018

Immunoglobulin G4-related disease (IgG4RD) is a chronic inflammatory condition characterized by tissue infiltration with lymphocytes and IgG4-secreting plasma cells, as well as varying degrees of fibrosis. We report a case of a 70-year-old man with a rapid-growing cervical mass for several months. Computed tomography and positron emission tomography showed a huge, ill-defined mass involving left thyroid lobe and encasing the common carotid artery, which was clinically and radiologically suspicious for anaplastic thyroid carcinoma. Ultrasonography-guided core needle biopsy was performed and histopathology examination revealed to be consistent with IgG4RD, and the IgG4/IgG ratio was 0.6. After oral corticosteroid was administered, the mass was dramatically resolved. Because IgG4RD often presents as a single localized and infiltrated mass lesion, it can be confused and misdiagnosed as a malignancy. Thus, clinicians should consider IgG4RD as a differential diagnosis in a rapid-growing neck mass to prevent unnecessary and excessive treatments.

• 한국태양에너지학회 논문집
• /
• 제39권2호
• /
• pp.45-55
• /
• 2019

More than 76% of the detached houses in Korea are over 20 years old. These old detached houses have poor energy efficiency. According to the 2017 Housing Census (Statistics Korea), more than 50% of low-income families live in detached houses. Therefore, the improvement of energy efficiency in old detached houses is needed from the viewpoint of energy welfare. The general method of building energy modelling for the verification of energy efficiency is based on the construction year data of "Building Design Criteria for Energy Saving" due to the cost and time involved in collecting the thermal performance data of buildings. There is poor accuracy with the deterioration of long-term aging of building materials. Also, the selection of alternatives for energy performance improvement is based on the items to be applied, not a performance improvement goal. It is difficult to calculate energy performance that reflects variations in various parameters with dynamic energy simulations. In this study, the influence of long-term aging is used to accurately predict the energy performance of old detached houses. The building energy modelling method is called ENERGY#, which is a static analysis method based on ISO13790. Energy performance is evaluated by a combination of input variables including building orientation, insulation of walls and roof, thermal performance of windows and window/wall ratio, and infiltration rate. Finally, this study provides a way to determine alternatives that meet energy performance improvement goals.

• 동의생리병리학회지
• /
• 제34권6호
• /
• pp.334-340
• /
• 2020

Nypa fruticans Wurmb. (NF) has been used as a folk remedy to treat inflammatory diseases in Asia. In this study, we aimed to investigate the protective effect of NF water extract on cerulein-induced acute pancreatitis (AP). To measure the protective effects of NF on AP, AP was induced via intraperitoneal injection of cerulein (50 ㎍/kg) hourly for 6 h in mice. NF water extract (100, 250, or 500 mg/kg) or saline was administrated to intraperitoneal injection 1 h before the first injection of cerulein. The mice were sacrificed at 6 h after the final injection of the cerulein. Pancreas, and blood sample were taken for further analysis. Administration of NF water extract inhibited the pancreatic injury, the elevation of pancreatic weight/ body weight ratio, and the elevation of serum digestive enzymes such as amylase and lipase during cerulein-induced AP in mice. Also, pancreas MPO activity, which represents neutrophil infiltration, was inhibited by administration of NF water extract. Taken together, administration of NF water extract reduces the severity of cerulein-induced AP, which suggests a clinical basis that NF could be a potential agent to prevent AP.

• 대한원격탐사학회지
• /
• 제36권6_3호
• /
• pp.1691-1710
• /
• 2020

본 연구에서는 평택과 부산의 초등학교를 대상으로 학교 주변과 교실 내를 포함하여 총 16개 지점에서 PM2.5(particulate matter less than 2.5 ㎛ in diameter) 및 PM10(particulate matter less than 10 ㎛ in diameter)을 동시에 측정하였고, 이 결과를 여러 국외 선행연구 리뷰를 통해서 획득한 실내·외 PM2.5 및 PM10 측정 농도 및 I/O ratio(Indoor/Outdoor ratio)와 비교하였다. 선행연구는 총 30건의 연구에서 144건의 사례를 수집하여 이를 실내활동, 측정 계절, 건물용도, 주변환경에 대해 다양한 항목별로 분류하여 본 연구의 측정결과와 비교하였다. 선행연구 결과에서 PM2.5는 흡연활동이나 요리활동 등의 실내 연소작용이 없는 환경에서는 외기농도가 실내농도에 중요한 영향을 미치는 반면, PM10은 외기농도와 함께 물리적 활동에 따른 재 비산이 중요한 실내 배출원일 것으로 보인다. 평택과 부산의 초등학교에서의 측정결과도 선행연구 리뷰 결론을 뒷받침하는 양상을 보였고, 공기청정기 사용이 미세먼지 저감에 효율적인 것으로 나타났다. PM2.5와 PM10은 실내 배출원 및 외기와의 상호작용 영향이 다를 수 있으며 환기방식에서는 강제환기가 자연환기보다 PM2.5와 PM10의 실내농도 감소에 더 효율적일 수 있는 것으로 보인다.

• 대한치과보철학회지
• /
• 제33권2호
• /
• pp.317-334
• /
• 1995

The purpose of this study was to compare the bone formation, maturation around HA-and titaniumcoated dental implants in dog. 5 hydroxyapatite coated IMZ implants and 5 titanium coated IMZ implants were placed into the previously extracted site in the mandible of 5 adults dogs. All dogs were injected intravenously Tetracycline, Alizalin red S, and Calcein for bone fluorescent labelling, After the experimental period of 16weeks, the dogs were sacrificed and tissue samples around the implants were obtained. Microscopic observations(ligth, polariged and fluorescence microscope), morphometric analysis, line profile with EPMA, and quantitative analysis for Ca,P, and Ti were performed. The results were as follows ; 1. Bone maturations around the implants were relatively lower than those of natural teeth. No significant differences in bone maturation and remodeling patterns were observed between the two implants groups. 2. Calcification of bone surrounding the implants was initiated in 8-11 weeks for HA-coated implants, while it took 11 weeks or more for Ti-coated implants. 3. Bone-to-implants contact ratio of 82.63% was recorded for HA-coated group and 72.25% for titanium coated group, with no significant difference between the two groups. 4. Bone around the implants exhibited reduced quantity of Ca and P in the $100{\mu}m$ region relative to natural teeth, while the rest of the regions showed no statistical differences. No significant differences were found between the two implant groups. 5. There was a separation of HA layer from the implant core and subsequent infiltration of inflammatory cells into the resulting space in the HA-coated implants, and evidences of phagocytosis of HA particles by macrophages. Bone calcification was more rapid around HA-coated implants compared to titanium-coated implants, but HA coated implants did not show any significant differences either in the degree of calcification or the bone-to-implant contact ratio over Ti coated implants. HA coated implants may have complications associated with HA absorption and separation of HA layer from the implant core.

• Biomolecules & Therapeutics
• /
• 제22권4호
• /
• pp.328-333
• /
• 2014

Vitiligo is a pigmentary disorder induced by a loss of melanocytes. In addition to replacement of pure melanocytes, cocultures of melanocytes with keratinocytes have been used to improve the repigmentation outcome in vitiligo treatment. We previously identified by in vitro studies, that adipose-derived stem cells (ADSCs) could be a potential substitute for keratinocytes in cocultures with melanocytes. In this study, the efficacy of pigmentation including durability of grafted melanocytes and short-term safety was examined in the nude mouse and Sprague-Dawley rat after grafting of primary cultured human melanocytes, with or without different ratios of primary cultured human ADSCs. Simultaneous grafting of melanocytes and ADSCs, which were separately cultured and mixed on grafting at the ratios of 1:1, 1:2, or 1:3, showed better efficacy than that of pure melanocytes. Grafting of melanocytes cocultured with ADSCs resulted in a similar outcome as the grafting of cell mixtures. Skin pigmentation by melanocytes : ADSCs at the ratios of 1:1 and 1:2 was better than at 1:3. No significant difference was observed between the 1-week and 2-week durations in coculturing. Time-course microscopic examination showed that the grafted melanocytes remained a little longer than 6-week post-grafting. No inflammatory cell infiltration was observed in the grafted skin and no melanocytes were detectable in other organs. Collectively, grafting of melanocytes and ADSCs was equally safe and more effective than grafting of melanocytes alone. Despite the absence of significant differences in efficacy between the group of 1:1 and that of 1:2 ratio, 1:2 ratio for 1-week coculturing may be better for clinical use from the cost-benefit viewpoint.

• 한방안이비인후피부과학회지
• /
• 제24권3호
• /
• pp.1-16
• /
• 2011

Objective : In the theory of Korean medicine, Scrophulariae Radix (SR) can clear away heat and cool the blood, nourish yin and promote the production of the body fluids, relieve toxin and benefit the throat. The present study was carried out to investigate effects of SR on allergic contact dermatitis (ACD) induced by 2,4-dinitrochlorobenzene (DNCB) in mice. Methods : In this experiment, effects of SR on clinical aspects on the skin, histopathological changes such as spongiosis, mast cell distribution, immune cell infiltration in tissue, spleen / body ratio and production levels of serum cytokines were investigated in vivo. In addition, effects on cell viability and release of b-hexosaminidase and histamine were also investigated in vitro. Results : SR treatment diminished erythema, desquamation and keratosis which were induced by repeated painting of DNCB. Spongiosis and edema were diminished by painting of SR in histopathological observation, infiltrations of mast cell and monocytes were also decreased in SR group. In addition, spleen / body ratio was lowered compared to ADC control group. Production level of IFN-${\gamma}$ in serum was decreased, but level of IL-4 did not affected by SR. Finally, more than 400 ${\mu}g/ml$ of SR treatment groups showed decreased cell viabilities in RBL-2H3 cells. Treatment with over 200 ${\mu}g/ml$ of SR decreased b-hexosaminidase release, and treatment with over 400 ${\mu}g/ml$ decreased histamine release in vitro. Conclusion : these data suggest that SR can decrease symptoms of ACD, then SR is useful to treat patient with ACD.

• 동의생리병리학회지
• /
• 제26권5호
• /
• pp.693-698
• /
• 2012

This study was designed to investigate the effects of 1-fluoro-2,4 dinitrobenzene (DNFB) on Induction of dermatitis in mice. We investigated the effects of DNFB on induction of dermatitis in terms of changes in body weights, ear thickness, ear weight, spleen/body ratio, histopathological observation and cytokine productions in inflammed tissue of contact dermatitis (CD) mice. In our experiments, we induced CD by using two different methods. First, mice were sensitized and challenged on the back of each ear (topical induction). Second, mice were sensitized on shaved back and challenged back of each ear (systemic induction). In our results, average weights were lowered in both topical and systemic group. But, there was no statistical significance between topical and systemic group. Treatment with DNFB enlarged ear weights and thicknesses in both topical and systemic groups. In addition, both groups were showed almost same features such as immune cell infiltration, spongiosis and hyperplasia in histopathological observations. Finally production levels of TNF-a, IFN-g and IL-6 were markedly elevated in both topical and systemic groups. On the other hand, systemic induction was more effective in spleen/body ratio and IL-6 production compared to topical induction respectively. These results suggest that dermatitis model using DNFB was used as model of CD, not for atopic dermatitis model.

• 한국물환경학회지
• /
• 제32권6호
• /
• pp.589-599
• /
• 2016

Implemented since 2004, TPLC (Total Pollution Load Control) is the most powerful water-quality protection program. Recently, uncertainty of prediction using steady state model increased due to changing water environments, and necessity of a dynamic state model, especially the watershed model, gained importance. For application of watershed model on TPLC, it needs to be feasible to adjust the relationship (mass-balance) between discharged loads estimated by technical guidance, and arrived loads based on observed data at the watershed outlet. However, at HSPF, simulation is performed as a semi-distributed model (lumped model) in a sub-basin. Therefore, if the estimated discharged loads from individual pollution source is directly entered as the point source data into the RCHRES module (without delivery ratio), the pollutant load is not reduced properly until it reaches the outlet of the sub-basin. The hypothetic RCHRES generated using the HSPF BMP Reach Toolkit was applied to solve this problem (although this is not the original application of Reach Toolkit). It was observed that the impact of discharged load according to spatial distribution of pollution sources in a sub-basin, could be expressed by multi-segmentation of the hypothetical RCHRES. Thus, the discharged pollutant load could be adjusted easily by modification of the infiltration rate or characteristics of flow control devices.