• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.4
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• pp.165-182
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• 2005

Purpose : To investigate the stress degree of infertile women and its correlations with Qi-stasis. Methods : 162 women, enrolled for treatment at oriental hospital, completed Infertility Stress Scale, Stress Response Inventory and Qi-stasis questionnaire. Their demographic features and infertility-related factors were recorded. 137 infertile women and 25 normal subjects were analyzed. Results : 1. 43 infertile women(33.86%) among the sample group were diagnosed as Qi-stasis. 2. There were close score correlations among Infertility Stress Scale, Stress Response Inventory, and Qi-stasis(p=.000). 3. Experience of Assisted Reproductive Technology (ART), possibility of spontaneous pregnancy, coitus frequency, whether the spouse is the eldest son or not had the influences on Infertility Stress. Abortion experience had influences on stress response and Qi-stasis. 4. It was revealed that Infertile women(n=137) had significantly higher scores of 'Infertility Stress' and subscales such as 'sexual satisfaction', 'marital satisfaction', 'familial adjustment', 'social adjustment' as well than control group(n=25). Conclusion : The results provide that the stress degree of infertile women had significant correlations with Qi-stasis and show the possibilities of oriental medicine treatment for stresses of infertile women.

• Women's Health Nursing
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• v.20 no.2
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• pp.163-172
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• 2014

Purpose: The purpose of this study was to determine the stress, depression, and fetal attachment of pregnant women who underwent infertility treatment, and to identify factors associated with fetal attachment. Methods: As a correlation survey design, data were collected from 136 pregnant women who underwent infertility treatment. Data were analyzed using ${\chi}^2$-test, t-test, ANOVA, Pearson correlation coefficients, and stepwise multiple regression. Results: Stress, depression, and fetal attachment averaged $3.01{\pm}0.60$ (range of scale 1~5), $10.02{\pm}6.51$ (out of a possible 63), and $3.64{\pm}0.55$ (range of scale 1~5), respectively. Level of fetal attachment was higher when mother's age was less than 35, having other children, and having prenatal education experience. Lower score of depression and client's age less than 35 were significant factors affecting fetal attachment. Conclusion: Infertility is a life-affecting trauma for the individual, and personal and social changes due to infertility cause physical and psychological difficulties even after a successful pregnancy with infertility treatment. Therefore, prenatal management programs need to be developed giving consideration to the emotional and physical changes in order to promote physical and psychological stability in the women pregnant following infertility treatment.

• 대한생식의학회:학술대회논문집
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• 2003.12a
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• pp.156.1-156.1
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• 2003

• Women's Health Nursing
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• v.1 no.2
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• pp.244-259
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• 1995

This study was designed and carried out to describe the stress of the infertile women and identify its predictors. The subjects of this study, 131 infertile women, were in primary or secondary infertility. the were conveniently sampled out from the infertility clinics of K University Medical Center and C Hospital in Seoul. The data were collected by using the Infertility Stress Scale which consisted of 35 items with four dimensions(cognitive, affective, marital and social stress) from August to November 1994. The data were analyzed by using the pc-SAS program. The information was obtained of Mean, Standard Deviation, Frequencies, Percentile, t-test, ANOVA, Duncan's multiple comparison test and Multiple Regression. The results are as follows; 1. The Mean of the stress of the infertile women is 2.78. The Means of the stress in 4 dimensions are 3.81 in the cognitive dimension, 3.05 in the affective dimension, 2.06 in the marital adjustment dimension and 2.41 in the social adjustment dimension. 2. The predictors of the stress of the infertile women are their educational levels and subjective economic status. They explain 14.08% of total variance.

• Clinical and Experimental Reproductive Medicine
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• v.48 no.2
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• pp.97-104
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• 2021

Male infertility has a complex etiopathology, which mostly remains elusive. Although research has claimed that oxidative stress (OS) is the most likely underlying mechanism of idiopathic male infertility, the specific treatment of OS-mediated male infertility requires further investigation. Coenzyme Q10 (CoQ10), a vitamin-like substance, has been found in measurable levels in human semen. It exhibits essential metabolic and antioxidant functions, as well as playing a vital role in mitochondrial bioenergetics. Thus, CoQ10 may be a key player in the maintenance of biological redox balance. CoQ10 concentrations in seminal plasma directly correlate with semen parameters, especially sperm count and sperm motility. Seminal CoQ10 concentrations have been shown to be altered in various male infertility states, such as varicocele, asthenozoospermia, and medical or surgical regimens used to treat male infertility. These observations imply that CoQ10 plays an important physiological role in the maintenance and amelioration of semen quality. The present article thereby aimed to review the possible mechanisms through which CoQ10 plays a role in the regulation of male reproductive function, and to concisely discuss its efficacy as an ameliorative agent in restoring semen parameters in male infertility, as well as its impact on OS markers, sperm DNA fragmentation, pregnancy, and assisted reproductive technology outcomes.

• Journal of Veterinary Clinics
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• v.16 no.1
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• pp.182-188
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• 1999

This study was performed to determine the causes of the bursting casualties such as death of sows and piglets, abortion, still birth and infertility in a pig farm after consecutive detonation for three months to construct 345 KV in Kimje area. 1. Temperatures in Kimje district, management condition, microorganism in the feed, inbreeding, hematological conditions, and viral agent causing abortion were not proved as the factors of acute occurrence of abortion and infertility in the pig farm. 2. The amount of explosive was increased from 250 kg to 1,100 kg from 23 Dec. 1996 to 28 Jan. 1997 and at the same time the distance between the spot of detonation and the pig farm got closer, from 200 m at the begining to 100 m at the last detonation. 3. Theoretical concussion and sound values were 0.66 kine and 89.39 ㏈, respectively, in the case of 100 m distance between the detonation spot and the pig farm. In conclusion, death of 675 piglets and 11 sows and infertility of 69 sows in the pig farm were assumed to be caused by the concussion or sound stress after detonation.

• Journal of Internet Computing and Services
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• v.24 no.4
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• pp.137-144
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• 2023

The purpose of this study is to examine consumers' perceptions of domestic infertility support policies based on infertility-related keywords and the trends of their changes. To this end, Momsholic, a mom cafe which has the most active infertility-related bulletin boards on Naver, was selected as the analysis target, and 'infertility' was selected as a keyword for data search. The data was collected for three months. In addition, network analysis and visualization were performed using R for data collection and analysis, and cross-validation was attempted using the NetDraw function of 'textom 1.0' and the UCINET6 program. As a result of the analysis, the main keywords were cost, artificial insemination, in vitro fertilization, freezing, harvest, ovulation, and how much. Next, looking at the central value of the degree of connection, it was found that the degree of connection between the words cost, cost, how much, problem, public health center, and artificial insemination was high. According to the results of this study, women who visit mom cafes due to infertility in Korea are more interested in the cost. It is believed to be closely related to infertility treatment as well as in vitro fertilization and egg freezing. Therefore, by examining keywords related toinfertility, it has academic significance in that it is possible to identify major factors that end users are interested in. Furthermore, it is possible to redefine the guidelines for domestic infertility support policies by presenting infertility support policies that reflect the factors of interest of end consumers.

• Women's Health Nursing
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• v.17 no.2
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• pp.178-186
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• 2011

Purpose: The purpose of this study was to identify effects of guided imagery on stress including cognitive, affective, marital and social, and anxiety among women receiving in vitro fertilization (IVF). Methods: Data were collected between April, 21 and June, 17, 2008. The participants in this study were 57 women (26 for the experimental group, 31 for the control group) receiving IVF for primary or secondary infertility in one of the outpatient infertility centers in Seoul. The guided imagery (Suk, 2001) was provided through audio CD to the experimental group by themselves 8 minutes per day for 2 weeks. Data were analyzed by SPSS 12.0 windows program. Results: After guided imagery, the experimental group showed significantly lower affective stress and total stress scores. Anxiety scores increased significantly in the control group, but not in the experimental group after treatment. Conclusion: The findings suggest that guided imagery is an effective nursing intervention for reducing stress especially affective stress and anxiety among infertile women receiving IVF in outpatient infertility center.

• Proceedings of the Korean Society of Developmental Biology Conference
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• 2003.10a
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• pp.97-97
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• 2003

Embryonic stem (ES) cells, derived from preimplantation embryos, are able to differentiate into various types of cells consisting the whole body, or pluripotency. In addition to the plasticity, ES cells are expected to be different from terminally differentiated cells in very many ways, such as patterns of gene expressions, ability and response of the cells in confronting environmental stimulations, metabolism, and growth rate. As a model system to differentiate these two types of cells, human ES (hES, MB03) cells and terminally differentiated cells (HeLa), we examined the ability of these two types of cells in confronting a severe oxidative insult, that is $H_2 O_2$. Ratio of dying cells as determined by the relative amount of dye neutral red entrapped within the cells after the exposures. Cell death rates were not significantly different when either MB03 or HeLa were exposed up to 0.4 mM $H_2 O_2$. However, relative amount of dye entrapped within the cells sharply decreased down to 0.12% in HeLa cells when the cells were exposed to 0.8 mM $H_2 O_2$, while it was approximately 54% in MB03. Pretreatment of cells with BSO (GSH chelator) and measurement of GSH content results suggest that cellular GSH is the major defensive mechanism of hES cells. Induction of apoptosis in hES cell was confirmed by DNA laddering, induction of Bax, and chromatin condensation. In summary, hES cells 1) are extremely resistant to oxidative stress, 2) utilize GSH as a major defensive mechanism. and 3) experience apoptosis upon exposure to oxidative stress.

• The Journal of Korean Obstetrics and Gynecology
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• v.36 no.3
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• pp.114-128
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• 2023

Objectives: This study was conducted to reflect Korean Medicine doctors (KMD)' perception of lifestyle management in the process of developing a Korean Medicine (KM) Clinical Practice Guidelines (CPG) of female infertility. Methods: We sent four e-mails containing links to online questionnaires to 25,286 KMD belonging to the Association of Korean Medicine. The questionnaire consisted of sexual intercourse, weight, diet, exercise, drinking, smoking, caffeine intake, stress etc. KMD responded to self-administered questionnaires, and we analyzed 786 responds. Results: KMD put stress first among the infertile women's lifestyle management items, weight and sexual intercourse were next. Also KMD put stress first among the spouses' lifestyle management items, drinking and sexual intercourse were next. In relation to sexual intercourse, 'Recognizing the Fertile Window' was the most important. In relation to stress in the emotional domain, 'Depression' and 'Anxiety' were the most important, and in relation to stress in the relationship domain, 'Deteriorating of marital relationship' was the most important. Conclusions: We surveyed the status of KMD' awareness of infertility lifestyle management for patient education, and reflected it in the modification of the CPG for female infertility.