• Tuberculosis and Respiratory Diseases
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• v.76 no.2
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• pp.84-87
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• 2014

We hereby observe four co-infection cases of pandemic influenza H1N1 and Mycobacterium tuberculosis with various clinical presentations. It may be prudent to consider M. tuberculosis co-infections when patients with pandemic influenza reveal unusual clinical features that do not improve despite appropriate treatments against the influenza, especially in Korea, in the endemic areas of M. tuberculosis.

• International Journal of Advanced Culture Technology
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• v.12 no.1
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• pp.43-50
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• 2024

Patients with acute respiratory diseases, such as Middle East Respiratory Syndrome (MERS) due to COVID-19, must wear masks, protective clothing, face shields, and gloves to prevent infection during treatment and performance. Even if it is applied to disabled people, families who protect them are severely mentally tired from severe physical fatigue and stress from exposure to high-risk infectious diseases. As such, the spread of infectious diseases such as respiratory diseases has not only caused difficulties in using existing welfare and medical services but also caused various problems throughout the daily life of disabled people due to the prolonged infectious disease, and its scope is gradually expanding. Therefore, it should not be overlooked that disabled people may experience various difficulties, from the spread of infectious diseases such as respiratory diseases to isolation, diagnosis, and treatment, and it is time to actively assess the life changes felt by families caring for disabled people and consider and research to provide adequate services. According to the survey of disabled people is being conducted in the context of the spread of infectious diseases such as respiratory diseases, while research on the spread of infectious diseases such as respiratory diseases is rare for parents with disabilities. There is a need for additional investigation into the characteristics in other areas of everyday life, including the health field, which is deteriorating through prior research. Therefore, through this survey, the purpose of this study is to investigate the life changes of parents with disabilities in the context of the spread of infectious diseases such as respiratory diseases and to compare and analyze them to find out how parents were affected by each type of disability. It will be used as evidence to identify more necessary needs and problems for parents with disabilities in the spread of infectious diseases such as respiratory diseases and to provide more appropriate health care and welfare services in the future.

• Clinical and Experimental Pediatrics
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• v.54 no.4
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• pp.146-151
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• 2011

Streptococcus pneumoniae remains a leading cause of invasive infections including bacteremia and meningitis, as well as mucosal infections such as otitis media and pneumonia among children and adults. The 7-valent pneumococcal conjugate vaccine (PCV7) was licensed for use among infants and young children in many countries including Korea. The routine use of PCV7 has resulted in a decreased incidence of invasive pneumococcal disease (IPD) by the vaccine serotypes among the vaccinees and substantial declines in IPD among unvaccinated populations such as older children and adults as well. In addition, there are increasing evidences to suggest that routine immunization with PCV7 is changing the epidemiology of pneumococcal diseases such as serotype distribution of IPD, nasopharyngeal colonization, and antibiotic resistance patterns. In contrast, there is an increase in the number of IPDs caused by nonvaccine serotypes, though it is much smaller than overall declines of vaccine serotype diseases. Several vaccines containing additional serotypes have been developed and tested clinically in order to expand the range of serotypes of Streptococcus pneumoniae. Recently two new pneumococcal protein conjugate vaccines, 10-valent pneumococcal conjugate vaccine (PCV10) and 13-valent pneumococcal conjugate vaccine (PCV13), have been approved for use in several countries including Korea. This report summarizes the recommendations approved by the Committee on Infectious Diseases, the Korean Pediatric Society.

• Journal of Medicine and Life Science
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• v.21 no.1
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• pp.1-10
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• 2024

The purpose of this study is to determine the issues of supplementation and improvement to prepare for the outbreak of new infectious diseases such as new variants of coronavirus disease 2019 (COVID-19) to guide work for a strategic new response to infectious disease. Public officials of Jeju Special Self-governing Province and health personnel responding to COVID-19, working at six public health centers in Jeju-do region were administered a survey about additional preparations to be made in the future, based on the period when COVID-19 was treated legally as a first-class infectious disease. Frequency analysis was conducted on the collected data. The Likert 5-point scale and Kruskal-Wallis test were used to compare the scores for effective response to emerging infectious diseases according to demographics. Among the important factors identified for effective response to new infectious diseases, 'facilitation of cooperation with public institutions' and 'facilitation of cooperation with private institutions' had the highest scores. In the future, when a patient presents with a new infectious disease, the step that needs to be supplemented in each phase of the public health center's response is 'immediate response team operation'. Further, public health centers responded that 'expansion of dedicated personnel related to infectious diseases' needs to be improved to respond to new infectious diseases. Along with the results of this study, considering the difficulties experienced by health personnel responding to new infectious diseases in preparation for future outbreaks of new infectious diseases, and to respond effectively, detailed and clear guidelines for responding to quarantine of patients of new infectious diseases will be needed.

• Journal of the Korean Institute of Oriental Medical Informatics
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• v.19 no.1
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• pp.44-142
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• 2013

The main purpose of this thesis is the Korean version of Gwang On Yeok Ron(廣瘟疫論). Gwang On Yeok Ron is a specialized book about infectious diseases(瘟疫). The book was compiled by Dae Cheon jang(戴天章) in 1722 who was a medical man in the Qing dynasty. The book consists of four volumes and an appendix. "Gwang On Yeok Ron Vol. I(廣瘟疫論卷之一)" is for the demonstration of colds(傷寒) and infectious diseases through a patient's odor(氣), skin tone(色), tongue(舌), mental state(神) and pulse(脈). Also, it describes the complications(兼證, 夾證) of infectious diseases. "Gwang On Yeok Ron Vol. II(廣瘟疫論卷之二)" describes the external symptoms(表證) of infectious diseases and the remedies. "Gwang On Yeok Ron Vol. III(廣瘟疫論卷之三)" describes the internal symptoms(裏證) of infectious diseases and the remedies. "Gwang On Yeok Ron Vol. IV(廣瘟疫論卷之四)" presents principles for the remedy of infectious diseases, and describes the sequelae(遺證) after the recovery of infectious diseases. "Appendix of Gwang On Yeok Ron(廣瘟疫論方目)" presents 83 prescriptions for the remedy of infectious diseases.

• Journal of the Korean Institute of Oriental Medical Informatics
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• v.19 no.2
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• pp.39-55
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• 2013

The main purpose of this thesis is the Korean version of "Gwang On Yeok Ron(廣瘟疫論)". Gwang On Yeok Ron is a specialized book about infectious diseases(瘟疫). The book was compiled by Dae Cheon jang(戴天章) in 1722 who was a medical man in the Qing dynasty. The book consists of four volumes and an appendix. "Gwang On Yeok Ron Vol. I(廣瘟疫論卷之一)" is for the demonstration of colds(傷寒) and infectious diseases through a patient's odor(氣), skin tone(色), tongue(舌), mental state(神) and pulse(脈). Also, it describes the complications(兼證, 夾證) of infectious diseases. "Gwang On Yeok Ron Vol. II(廣瘟疫論卷之二)" describes the external symptoms(表證) of infectious diseases and the remedies. "Gwang On Yeok Ron Vol. III(廣瘟疫論卷之三)" describes the internal symptoms(裏證) of infectious diseases and the remedies. "Gwang On Yeok Ron Vol. IV(廣瘟疫論卷之四)" presents principles for the remedy of infectious diseases, and describes the sequelae(遺證) after the recovery of infectious diseases. "Appendix of Gwang On Yeok Ron(廣瘟疫論方目)" presents 83 prescriptions for the remedy of infectious diseases.

• Korean Journal of Veterinary Research
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• v.53 no.1
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• pp.65-68
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• 2013

Hepatitis E virus (HEV) can infect not only human but also several animals. This study has been conducted to evaluate the comprehensive anti-HEV seroprevalence in zoo animals in Korea. Anti-HEV antibodies were identified in 14 of 64 zoo animal species. HEV antibodies were detected for the first time in Eurasian Lynx, Setland Pony, Fallow Deer, Ezo Sika, Formosa Deer, East Wapitis, Barasingha, Corriedale, American Bison, Guanacos, Reticulated Giraffe, and Saanen. These results indicate that the several zoo animal species were exposed to HEV.

• Korean Journal of Veterinary Research
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• v.63 no.2
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• pp.15.1-15.5
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• 2023

The hepatitis A virus (HAV) induces severe acute liver injury and is adapted to human and monkey cell lines but not other cells. In this study, the HAV was inoculated into porcine kidney (PK-15) cells to determine its infectivity in porcine cells. The growth pattern of the HAV in PK-15 cells was compared with its growth pattern in fetal rhesus kidney (FRhK-4) cells. The growth of HAV was less efficient in PK-15 cells. In conclusion, HAV replication was verified in PK-15 cells for the first time. Further investigations will be needed to identify the HAV-restrictive mechanisms in PK-15 cells.

• Journal of Microbiology and Biotechnology
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• v.24 no.3
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• pp.421-426
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• 2014

To characterize the extended-spectrum beta-lactamases (ESBLs) in diarrheagenic Escherichia coli from Korea in 2008-2011, we screened seven enterotoxigenic E. coli (ETEC) and one enteroaggregative E. coli (EAEC) that produce ESBLs from a nationwide survey. All eight isolates produced CTX-M-type ESBLs, including CTX-M-12 (n = 4), CTX-M-14 (n = 2), and CTX-M-15 (n = 2). PCR-based replicon typing indicated that the $bla_{CTX-M-12}$ genes of four ETEC isolates were carried on a conjugative IncF plasmid, whereas the $bla_{CTX-M-14}$ of one EAEC was located on an IncK plasmid. This is the first report of the occurrence of $bla_{CTX-M}$ genes in clinical isolates of EAEC in Korea. The ESBL-producing isolates were shown to be different based on pulsed-field gel electrophoresis and multilocus sequence typing, whereas the four isolates with CTX-M-12 were clonally related. These observations raise an alarm for the spread of plasmid-mediated resistance to ESBL among diarrheagenic E. coli.

• Korean Journal of Poultry Science
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• v.48 no.4
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• pp.327-335
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• 2021

Riemerella anatipestifer (RA) can cause septicemia, polyserositis, and ataxia in ducks. It can also colonize the upper respiratory tract of healthy ducks. These differences in pathogenicity are probably the result of diverse mechanisms of virulence in different strains. Since serum resistance is a feature frequently found in systemic pathogens, 130 RA strains having different clinical origins were tested. A variety of serum susceptibility levels were detected. Pharynx strains from healthy ducks were mainly susceptible to the bactericidal effect of the serum, while systemic strains were serum resistant. Heat-treatment of the sera abolished the bactericidal activity, indicating that complement is a key factor in this effect. In an attempt to associate serum-resistance to surface determinant genes of the bacteria, we screened for six genes involved in lipopolysaccharide synthesis and membrane proteins in RA. Of these, three genes (AS87_09335, AS87_00480, and AS87_05195) encoding outer membrane proteins might be implicated in serum resistance statistically. The results indicate that serum resistance is a virulence mechanism in RA.