Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
권호 표지
DOI QR코드

DOI QR Code

Pandemic Influenza (H1N1) and Mycobacterium tuberculosis Co-infection

  • Park, Yehyun (Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Chin, Bum Sik (Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Han, Sang Hoon (Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Yun, Yujung (Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Young Ju (Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Choi, Jun Yong (Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, Chang Oh (Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Song, Young Goo (Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine) ;
  • Kim, June Myung (Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine)
  • Received : 2013.08.31
  • Accepted : 2013.10.14
  • Published : 2014.02.28
Download PDF
⟨ Previous Next ⟩

Abstract

We hereby observe four co-infection cases of pandemic influenza H1N1 and Mycobacterium tuberculosis with various clinical presentations. It may be prudent to consider M. tuberculosis co-infections when patients with pandemic influenza reveal unusual clinical features that do not improve despite appropriate treatments against the influenza, especially in Korea, in the endemic areas of M. tuberculosis.

Keywords

References

  1. Centers for Disease Control and Prevention (CDC). Outbreak of swine-origin influenza A (H1N1) virus infection: Mexico, March-April 2009. MMWR Morb Mortal Wkly Rep 2009;58:467-70.
  2. Ellner JJ. Immunosuppression in tuberculosis. Infect Agents Dis 1996;5:62-72.
  3. Kantzler GB, Lauteria SF, Cusumano CL, Lee JD, Ganguly R, Waldman RH. Immunosuppression during influenza virus infection. Infect Immun 1974;10:996-1002.
  4. Lofgren S, Callans A. Asian influenza and pulmonary tuberculosis. Acta Med Scand 1959;164:523-7.
  5. Puvanalingam A, Rajendiran C, Sivasubramanian K, Ragunanthanan S, Suresh S, Gopalakrishnan S. Case series study of the clinical profile of H1N1 swine flu influenza. J Assoc Physicians India 2011;59:14-6, 8.
  6. Koegelenberg CF, Irusen EM, Cooper R, Diacon AH, Taljaard JJ, Mowlana A, et al. High mortality from respiratory failure secondary to swine-origin influenza A (H1N1) in South Africa. QJM 2010;103:319-25. https://doi.org/10.1093/qjmed/hcq022
  7. Housworth J, Langmuir AD. Excess mortality from epidemic influenza, 1957-1966. Am J Epidemiol 1974;100:40-8. https://doi.org/10.1093/oxfordjournals.aje.a112007
  8. Archer B, Cohen C, Naidoo D, Thomas J, Makunga C, Blumberg L, et al. Interim report on pandemic H1N1 influenza virus infections in South Africa, April to October 2009: epidemiology and factors associated with fatal cases. Euro Surveill 2009;14. pii: 19369.
  9. World Health Organization. Global tuberculosis report 2012 [Internet]. Geneva: World Health Organization; 2012 [cited 2013 Oct 1]. Available from: http://www.who.int/tb/publications/ global_report/en/.
  10. Noh JY, Lee J, Choi WS, Song JY, Seo YB, Kim IS, et al. Concurrent tuberculosis and influenza, South Korea. Emerg Infect Dis 2013;19:165-7. https://doi.org/10.3201/eid1901.111613
  11. Volkert M, Pierce C, Horsfall FL, Dubos RJ. The enhancing effect of concurrent infection with pneumotropic viruses on pulmonary tuberculosis in mice. J Exp Med 1947;86:203-14. https://doi.org/10.1084/jem.86.3.203
  12. Co DO, Hogan LH, Karman J, Heninger E, Vang S, Wells K, et al. Interactions between T cells responding to concurrent mycobacterial and influenza infections. J Immunol 2006;177:8456-65. https://doi.org/10.4049/jimmunol.177.12.8456
  13. Jiang TJ, Zhang JY, Li WG, Xie YX, Zhang XW, Wang Y, et al. Preferential loss of Th17 cells is associated with CD4 T cell activation in patients with 2009 pandemic H1N1 swine-origin influenza A infection. Clin Immunol 2010;137:303-10. https://doi.org/10.1016/j.clim.2010.07.010

Cited by

  1. Mortality and transmissibility patterns of the 1957 influenza pandemic in Maricopa County, Arizona vol.16, pp.None, 2016, https://doi.org/10.1186/s12879-016-1716-7
  2. Mechanisms of Severe Mortality-Associated Bacterial Co-infections Following Influenza Virus Infection vol.7, pp.None, 2017, https://doi.org/10.3389/fcimb.2017.00338
  3. Tuberculosis as a Risk Factor for 1918 Influenza Pandemic Outcomes vol.4, pp.2, 2014, https://doi.org/10.3390/tropicalmed4020074