• Parasites, Hosts and Diseases
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• v.52 no.4
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• pp.443-447
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• 2014

Babesiosis is an emerging tick-borne disease in humans worldwide; however, little is known about the frequency of infection or prevalence of this disease in other parts of the world, excluding North America. In this study, we aimed to investigate Babesia microti infection frequency in a human population in Mongolia. One hundred blood samples were collected from stock farmers living in Khutul city of Selenge province, Mongolia. The sera and DNA from blood samples were evaluated for the presence of B. microti infection by using indirect fluorescent antibody (IFA) tests and PCR. The positive detection rates obtained using the IFA tests and PCR assays were 7% and 3%, respectively. This study is the first to detect of B. microti infections based on antibody seroprevalence or PCR assays for the presence of B. microti DNA in a Mongolian population.

• Research in Community and Public Health Nursing
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• v.24 no.4
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• pp.398-406
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• 2013

Purpose: The study was conducted to clarify effects of a clonorchiasis prevention education program for clonorchiasis prevention lecturers. Methods: The research adopted a single group pretest-posttest design to see effects of the educational program to prevent Clonorchis sinensis infection. The subjects of this study were 74 clonorchiasis prevention lecturers from primary health care facilities. The pretest was conducted before the clonorchiasis prevention education program and the post test was done after the 2-day program in August, 2011. Descriptive statistics, t-test, and ANOVA were conducted to analyze the data. Results: The confidence level in Clonorchiasis management activities was improved significantly from $4.1{\pm}0.53$ points before the education to $4.4{\pm}0.46$ points after the education (t=-5.117, p<.001). The knowledge level about prevention of Clonorchis sinensis was improved significantly from $16.1{\pm}2.72$ points before the education to $18.3{\pm}1.14$ points after the education (t=-6.629, p<.001). Conclusion: The results suggest that the education program was effective in improving the confidence and knowledge levels in Clonorchiasis management activities for the clonorchiasis prevention lecturers. Based on the results of this study, continuous research on how the increased knowledge and confidence levels of Clonorchis sinensis prevention affect the prevalence of Clonorchis sinensis infection.

• The Korean Nurse
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• v.18 no.5 s.103
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• pp.73-83
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• 1979

This study was intended to provide fundamental data for some help of effective nursery management and for the prevention of hospital infection of infants by testing the contamination level of nursery room. The nursery room of the E. University Hospital wa

• Journal of The Korea Institute of Healthcare Architecture
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• v.10 no.2
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• pp.29-37
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• 2004

Recently the hospital infection with misappropriation of the antibiotic and absence of knowledge is aincreaseing trend. For this, medical treatment is confronting infection management guide. But so far there is no accurate standard or countermeasures. Since early 1990 Nosocomial Infection has not been looked over, although there is serious problem. After 90's understanding seriousness of Nosocomial Infection, many investigations have been done, but the relations of medical facilities were hardly investigated. This thesis shows the relation between facilities and Nosocomial Infection by documental references and the direction for intensive care unit through survey the recent general hospitals.

• Journal of the Korea Convergence Society
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• v.7 no.3
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• pp.59-69
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• 2016

The purpose of this study was to provide basic materials on establishing convergence oriented respiratory infection management system in nursing students attending clinical training by analyzing anxiety, knowledge, possibility of infection, possibility of prevention, and compliance level of preventive behavior. Data were collected from 222 nursing students experienced clinical practice from June 15th to 30th in 2015 using questionnaire. Characteristics relative to variables were measured, and analyzed using SPSS 18.0 program. The results are as follows. The anxiety was 42.70(max 80 points), but possibility of infection was 22.55(max 100 points). Also, knowledge(11.73 out of 16 points), possibility of prevention(7.37 out of 10 points), and compliance level of preventive behavior(34.55 out of maximum 48 points) were slightly above average. The influencing factors on compliance of preventive behavior were anxiety and possibility of prevention. It is needed to lead convergence oriented approach on enhancing compliance of preventive behavior through providing information and educating possibility of prevention during MERS outbreak.

• Journal of Microbiology and Biotechnology
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• v.19 no.3
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• pp.323-330
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• 2009

Nontuberculous mycobacteria (NTM) are a major cause of opportunistic infections in immunocompromised patients, making the reliable and rapid identification of NTM to the species level very important for the treatment of such patients. Therefore, this study evaluated the usefulness of the novel target genes tuf and tmRNA for the identification of NTM to the species level, using a PCRrestriction fragment length polymorphism analysis (PRA). A total of 44 reference strains and 17 clinical isolates of the genus Mycobacterium were used. The 741 bp or 744 bp tuf genes were amplified, restricted with two restriction enzymes (HaeIII/MboI), and sequenced. The tuf gene-PRA patterns were compared with those for the tmRNA (AvaII), hsp65 (HaeIII/HphI), rpoB (MspI/HaeIII), and 16S rRNA (HaeIII) genes. For the reference strains, the tuf gene-PRA yielded 43 HaeIII patterns, of which 35 (81.4%) showed unique patterns on the species level, whereas the tmRNA, hsp65, rpoB, and 16S rRNA-PRAs only showed 10 (23.3%), 32 (74.4%), 19 (44.2%), and 3 (7%) unique patterns after single digestion, respectively. The tuf gene-PRA produced a clear distinction between closely related NTM species, such as M. abscessus (557-84-58) and M. chelonae (477-84-80-58), and M. kansasii (141-136-80-63-58-54-51) and M. gastri (141-136-117-80-58-51). No difference was observed between the tuf-PRA patterns for the reference strains and clinical isolates. Thus, a diagnostic algorithm using a tuf gene-targeting PRA is a promising tool with more advantages than the previously used hsp65, rpoB, and 16S rRNA genes for the identification of NTM to the species level.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.3
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• pp.360-369
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• 2020

This study examined and compared the droplet infection prevention activity and cough etiquette knowledge among nursing hospital workers. Data were collected from March 4 to 29, 2019, through personal interviews using a questionnaire in 177 nursing hospital workers (health care provider: n=61, non-health care provider: n=116). The data were analyzed using a x²-test, Fisher's exact test, independent t-test, and ANOVA. The general characteristics were statistically significant between the two groups in terms of sex and age. The prevention activities of droplet infection showed statistically significant differences between the two groups in usually carrying a tissue, usually carrying a handkerchief, usually carrying a mask, carrying a handkerchief at respiratory symptoms, hand washing frequency, and cough etiquette compliance. Knowledge of cough etiquette showed significant differences between the two groups. The knowledge of cough etiquette, according to the non-health provider's prevention activities of droplet infection, was statistically significant in usually carrying a mask and cough etiquette education. Therefore, it is necessary to raise the knowledge about cough etiquette and develop strategies for habitual cough etiquette for each nursing hospital worker.

• Journal of Pharmacopuncture
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• v.26 no.1
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• pp.18-26
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• 2023

Objectives: Terminalia chebula, the main ingredient of Altan Arur 5, has been used for many years in traditional medicine. This medicine is more effective than other drugs and is used to treat chronic gastritis and gastrointestinal disorders such as peptic ulcers and esophageal reflux. Other ingredients of Altan Arur 5 are Punica granatum (pomegranate), tulip seeds, black balm, and excreta of Trogopterus xanthipes. The main ingredients of T. chebula are antibacterial and analgesic in traditional medicine. Despite having been used for many years and although many studies have been conducted on the beneficial effects of this medicine and its ingredients, the toxicity of Altan Arur 5 has not yet been elucidated. Therefore, we aimed to study the toxicity of Altan Arur 5 to ensure that it is safe to use. Methods: Acute and chronic toxicity of Altan Arur 5 were assessed in 10 Kunming mice and 8 Sprague-Dawley rats, respectively, in different doses. In the acute toxicity study, Altan Arur 5 was orally administered to Kunming mice in doses of 12 g/kg, 24 g/kg, and 48 g/kg for 14 days. In the chronic toxicity study, it was orally administered to Sprague-Dawley rats in doses of 1.25 g/kg, 2.5 g/kg, and 5 g/kg for 12 weeks. Results: No significant differences were observed in the relative organ weights for mice treated with Altan Arur 5 compared with those in the control group. Furthermore, no macro- or microstructural changes were noted in the organs of any group. Conclusion: Our toxicity testing revealed that the traditional medicine Altan Arur 5 has no toxic effects in vivo.

• The Journal of the Convergence on Culture Technology
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• v.9 no.5
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• pp.19-25
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• 2023

This study was conducted to confirm the level of stress and infection prevention behavior of nursing college freshman during the COVID-19 pandemic. 119 nursing college freshmen who took remote classes because face-to-face classes were not possible due to the COVID-19 pandemic. The collected data were analyzed by descriptive statistics, Independent t-test, one-way ANOVA, and Pearson's correlation coefficient using SPSS WIN/PC 26.0 statistics program. As a result of this study, the sensitivity to stress was significantly higher when the attitude towards college life was passive (F=5.92, p=.004), and when people perceived themselves as healthy, their stress was significantly lower (t=-2.22, p=.029). In addition, those who responded that they were very uncomfortable due to activity restrictions due to COVID-19 had a significantly higher level of infection prevention behavior than those who responded that they did not feel any discomfort (F=3.51, p=.018). In a pandemic environment such as COVID-19, efforts to promote a positive attitude and awareness of health conditions are needed to reduce the stress of college freshmen and increase infection prevention behavior.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.2
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• pp.599-606
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• 2012

The characterization of the whole genome of human papillomavirus type 16 (HPV16) from cervical cancer specimens with multiple infections in comparison with single infection samples as the oncogenic potential of the virus may differ. Cervical carcinoma specimens positive for HPV16 by PCR and INNO-LiPA were randomly selected for whole genome characterization. Two HPV16 single infection and six HPV16 multiple infection specimens were subjected to whole genome analysis by using conserved primers and subsequent sequencing. All HPV16 whole genomes from single infection samples clustered in the European (E) lineage while all multiple infection specimens belonged to the non-European lineage. The variations in nucleotide sequences in E6, E7, E2, L1 and Long control region (LCR) were evaluated. In the E6 region, amino acid changes at L83V were related to increased cancer progression. An amino acid variation N29S within the E7 oncoprotein significantly associated with severity of lesion was also discovered. In all three domains of the E2 gene non synonymous mutations were found. The L1 region showed various mutations which may be related to conformation changes of viral epitopes. Some transcription factor binding sites in the LCR region correlated to virulence were shown on GRE/1, TEF-1, YY14 and Oct-1. HPV16 European variant prone to single infection may harbor a major variation at L83V which significantly increases the risk for developing cervical carcinoma. HPV16 non-European variants prone to multiple infections may require many polymorphisms to enhance the risk of cervical cancer development.