The purpose of this study was to examine the level of stress, healthcare accreditation related job stress, adaptation, and turnover intentions, as well as to identify influencing factors of turnover intentions for operating room nurses. This study employed a descriptive correlational design. The data were collected from 163 operating room nurses using a structural questionnaire. Stress was different by age (F=5.629, p=.004), marital status (t=-2.907, p=.004), and children (t=-2.623, p=.010). Healthcare accreditation related job stress was different by age (F=11.924, p<.001), marital status (t=-4.747, p<.001), children (t=-4.434, p<.001), work experience in the OR (F=6.000, p=.003), and work reasons in the OR (t=-2.543, p=.012). Turnover intention was different by age (F=21.472, p<.001), education level (F=4.997, p<.008), religion (t=3.235, p=.001), work experience in the OR (F=13.599, p<.001), position (t=3.222, p=.002), work reasons in the OR (t=-3.001, p=.003), and a shift pattern of duties (t=-2.797, p=.006). Turnover intention was significantly correlated with stress, healthcare accreditation related job stress, and adaptation. Factors affecting turnover intention were healthcare accreditation related job stress, adaptation, and age. These factors accounted for 36.2% of turnover intention. These results suggest that relief of stress and healthcare accreditation related job stress and interventions for improving stress management.