• Tuberculosis and Respiratory Diseases
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• v.44 no.1
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• pp.183-190
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• 1997

Tocolytics are agents widely used in the treatment of premature labor to inhibit uterine contractions. Ritodrine is most commonly used tocolytic agent and acts by increasing intracellular cyclic adenosine monophosphate, which decreases the activity of myosin light-chain kinase, the rate-limiting enzyme in the signal network leading to contraction. Physiologic effects associated with the use of ritodrine are due to their effect on bera-l as well as beta-2 receptors. Some of maternal complications of therapy are rachycardia, hyperglycemia, hypokalemia, lactic acidosis, myocardial ischemia, and pulmonary edema. Tocolytics induced pulmonary edema is a serious complication that can lead to marternal death, although infrequent, The incidence varies from 0.5% to 5% of those receiving these agents. Predisposing factors include the concommitant use of corticosteroid, twin gestation, fluid overload (particularly with saline), and anemia. Several mechanisms have been postulated, but the pathogenesis is uncertain. It is suggested that both types of mechanism, hydrostatic and permeability induced, might be involved. The association of tocolytic therapy with pulmonary edema appears to be unique to the pregnant state, because this complication has never been reported in asthmatic patients exposed to high dosages. We report a case of tocolytic induced pulmonary edema developed in 24 hours after delivery.

• Journal of the Korean Society of Tobacco Science
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• v.26 no.2 s.52
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• pp.152-158
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• 2004

Among short-term in vitro genotoxicity assays, micronucleus assays are rapid, inexpensive, and less labor-intensive system. We have undertaken a comparative study of sensitivity of cigarette smoke condensate(CSC) by general micronucleus(MN) assay and cytokinesis-block micronucleus(CBMN) assay. In this study, V79 Chinese hamster cells were employed to evaluate and compare the genotoxicity of CSC of Kentucky Reference Cigarette 2R4F by 2 kinds of in vitro MN assay methods. To determine the optimum concentration of cytochalasin B(CYB) to obtain the maximal number of binucleated cells for CBMN assay, triplicate cultures of growing cells were treated with CYB for 15 h. CYB treatments caused a concentration-dependent increase in cytotoxicity($1\~4{\mu}g/mL$) and proportion($0.25\~1\;{\mu}g/mL$) of binucleated cells. These data suggested that 1 ug/mL of CYB is as an optimum dose for CBMN assay in binucleated V79 cells. Short treatment(4 h) of CSC induced a micronucleated cells with a concentration-dependent response in the presence or absence of CYB, but CSC-induced MNs were weakened when S9 was present. Long treatments(19 h) of CSC also induced a significant increase MN formation with a concentration-dependent response. At a concentration of 75 ${mu}g/mL$, the MN cell frequencies of general MN assay and CBMN assay were $6.5\%\;and\;11.7\%$, respectively. Linear regression analysis revealed a good correlation in CBMN assay between a concentration of CSC and MN cell frequency. All these data indicated that CBMN assay is more sensitive to the induction CSC-induced MN than general MN assay.

• Health Policy and Management
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• v.14 no.2
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• pp.99-116
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• 2004

This study estimates the determinants of national health expenditures of OECD countries using panel regression method. The data used are OECD Health Data(2003) covering 33 countries and from 1970 to 2001. This study shows several important different results compared to the previous studies. Further this study estimates the determinants of Korean case using data from 1m to 2000, and compare with the results of OECD panel. The main findings are as follows. The income elasticity of health expenditures is estimated below 1.0, but is shown above 1.0 when the different health systems of each country are controlled. The women's labor participation influences strongly positive effect on the health expenditures. The diffusion of new technologies is positively related with the increasing expense. The increasing government expenditures have a tendency not to contain health expenses, but to increase expenses. The expansion of public health insurance holders is containing the expenses, and the increasing number of doctors is pushing expenditures. This implies the health expenditures are influenced more by the induced demand of providers rather than the moral hazard of patients. However, the above result is opposite in Korean case. The existence of primary care doctors affects slightly up warding rather than containing expenditures. Finally the determinants are seriously depending upon which factors are included in the model and which statistical model is chosen. Therefore it must be cautious to interpret the results of statistical model.

• Journal of Environmental Health Sciences
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• v.34 no.2
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• pp.153-160
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• 2008

Personal noise exposure was assessed in railroad operators working in 40 operation units including the Gyeongbu line, Honam line, and Janghang line between 2004 and 2006. 8-hour TWA were assessed based on the MOL (Ministry of Labor) guideline on noise evaluation, and 17% of these measurements exceeded 85 dBA while 70% were over 80 dBA. When the ACGIH TLV is adopted, 40% of measurements were over TLV (85 dBA). The noise exposure risk of railroad operators was higher for diesel locomotive operation and longer operational distances; in addition, the risk was higher for passenger car operation compared to freight car driving. Given that in Korea, over the past 30 years diesel locomotives have provided most of the railway's motive power and that hearing protective equipment is not likely to be used by workers during operation, railroad operators are at a high risk of noise-induced hearing loss. The result of audiometric test among 568 railroad operators showed that 32.6% of those tested had a hearing threshold shift of more than 40 dB. In conclusion, this study calls for more fundamental measures including noise control countermeasures within the operation areas, development of equipment that generates less noise and adopting limitation on the operation distance for a work shift.

• Korean Journal of Rural Living Science
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• v.10 no.2
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• pp.85-100
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• 1999

This study was to get basic data for the establishment of proper labor counterplan so that we estimated farm work volume and work loads by crops. We examined the method of work practices such as a work posture, work time, measured work environment such as hot, cold, humidity and ultraviolet rays and calculated physical loads induced by them. Also we surveyed work environment, work posture, sleeping time and work time because they affect on farmer's health. Farmer's health survey was investigated by questionnaire and measured farmer's physical load. The types of farm work were classified into greenhouse farming, rice farming, dry field farming, stock farming and special crop farming. 11 crops were selected, for example, greenhouse melon, riceㆍred pepper, milky cow farming, pear, grapes, dropwort, sweet potato, potato, radish, and cabbage. We also chose subject districts haying the most yield of 11 crops. Our survey was conducted for the period when farmers think the hardest period in physical work load. The farm work models based on work standard were presented according with farmer's health.

• Korean Journal of Acupuncture
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• v.25 no.1
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• pp.51-60
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• 2008

Objectives : The aim of this study was to investigate the mechanism and the clinical significance of prohibition of acupuncture of LI4 and SP6 during the period of pregnancy. Methods : It was investigated the prohibition of acupuncture during the period of pregnancy based on the literature reviews. Previous studies identified the acupuncture treatment of animal and clinical studies during the period of pregnancy and labor in China Academic Journal(CAJ). These papers were classified and investigated to clarify the rationale of the prohibition of acupuncture during the period of pregnancy. Results and Conclusions : The contraindicated points during the period of pregnancy are Hapgok (LI4), Samumgyo (SP6), Songmun (CV5), Kwanwon (CV4), Sosang (LU11), Chium (BL67), Kollyun (BL60). The uterine contraction can be induced by the stimuli of Hapgok (LI4) via endocrine system and Samumgyo (SP6) via nervous system. Both Hapgok (LI4) and Samumgyo (SP6) also can be used in various diseases such as induction of abortion, facilitation of parturition, stabilization of embryos, cross birth and so on.

• Journal of the Korean Regional Science Association
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• v.11 no.1
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• pp.1-20
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• 1995

This paper studies the comparative advantage of competitive and specialized regional industries which are manufacturing, wholesale and retail trade, servies in the metropolitan area-Seoul, Inchun, Kyunggi-do of Korea, For the analysis of industries, the coefficient of specialization, the indices of competitiveness of labor and value-added, the growth rate are simultaneously examined under the criteria of the number of workers, value of shipment, value-added, This comperative synthetic analysis is different from the traditional approaches. This paper shows that the perfectly competitive advantage of specialized industries satisfying all of three criteria are 'other business related activities', 'recreational, cultural and sporting activities' in Seoul, 'machinery and outfits, n.e.c', 'retail trade, except of motor vehicles and motorcycles, repair of personal and household goods' in Inchun. We conclude that each should strategically develop the region-oriented specialized industry which has the comparative advantage. It is the reason why the concentration of industry in necessary for the leading of regional industry under the weaken local public finance. Moreover, such an industy should provide the increase of employment and income from the viewpoint of the activation of regional economy. The potential-specialized competitive industry requires the advanced structure of production under the criteria of value-added. For the development of the metropolitan area's economy, the highly advanced technology industry including computer and electronics should be induced through the loosening of metropolitan regulation. Research center(science park) supported by th private-public sector should be built for the increase of technology sector should be built for the increase of technology power of the small and medium enterprises, Also it is necessary that the small and medium enterprises strategically make the cooperative-large group in order to avoid the disadvantage from the size.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.45 no.5
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• pp.335-338
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• 2000

The technology of direct-seeding in rice cultivation is an innovation mainly induced by factors in market economy and is rapidly diffused among individual farmhouses. Because the effect of technology can be affected by many factors under various farming circumstances, the impact and stability of the direct-seeding technology compared with transplanting was analyzed under various topographical regions. Yield in direct-seeding was higher in plains, although the farm size producing higher yield was quite different depending on the topographical regions. In the direct-seeding cultivation of rice, man-labor hours was reduced by about 38 percent and the reduction rate showed little difference among topographical regions. Fertilizer was used about 11 percent more but the increase rate varied from 3 to 17 percent depending on regions with higher rates in plains. Application of agricultural chemicals was also increased about 9 percent in direct-seeding, but the increase rate was as high as 12 percent in suburbs. More fertilizer and agricultural chemicals were used in direct-seeding cultivation by farmhouses implementing both direct-seeding and transplanting than by those implementing direct-seeding only. Use of more fertilizers and agricultural chemicals in direct-seeding in all regions may indicate its technical instability. Major problems causing the technical instability of direct-seeding cultivation should be solved by comprehensive research considering various farming circumstances such as topographical features rather than just a top-down style research and extension.

• Structural Engineering and Mechanics
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• v.84 no.6
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• pp.799-811
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• 2022

Adhesive bonding has seen rapid development in recent years, with emphasis to composite patch repairing processes of geometric defects in aeronautical structures. However, its use is still limited given its low resistance to climatic conditions and requirement of specialized labor to avoid fabrication induced defects, such as air bubbles, cracks, and cavities. This work aims to numerically analyze, by the finite element method, the failure behavior of a damaged plate, in the form of a bonding defect, and repaired by an adhesively bonded composite patch. The position and size of the defect were studied. The results of the numerical analysis clearly showed that the position of the defect in the adhesive layer has a large effect on the value of J-Integral. The reduction in the value of J-Integral is also related to the composite stacking sequence which, according to the mechanical properties of the ply, provides better load transfer from the plate to the repair piece through the adhesive. In addition, the increase in the applied load significantly affects the value of the J-Integral at the crack tip in the presence of a bonding defect, even for small dimensions, by reducing the load transfer.

• Proceedings of the Korea Water Resources Association Conference
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• 2023.05a
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• pp.24-24
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• 2023

This presentation highlights the IAHR book, recently published last April, of which the author is the editor-in-chief, on the historical water projects and traditional water technologies of international interest in the Asian region, addressing information on past water projects (mostly before the 20th century) in the regions that are technically and culturally of interest and educationally valuable. The book explores historical water projects in these regions, presenting technologies used at the time, including calculation and forecasting methods, measurement, material, labor, methodologies, and even water culture. Through this book, it is expected that the old Asian wisdom of "reviewing the old and learning the new" would be realized to a certain extent in modern planning and practice of water projects. The book comprises a lead article that the presenter authored and five Parts representing China, Japan, Korea, South Asia, and Southeast Asia, respectively, followed by an invited one from Uzbekistan. Throughout the book, it is found that historically the Asian monsoon, affecting the Indian subcontinent and Southeast and East Asian regions, induced rice cultivation. It fundamentally needs proper irrigation systems, including reservoirs (dams) and canals, water wheels, and even rain gauges. Flood risks have been more common in Asia than Europe under this climate condition, as recognized in history. To utilize and sometimes overcome these climate conditions, people built and managed many historical and grandiose water projects and invented and used localized but sophisticated water-related technologies in the Asian region.