• Bulletin of the Korean Chemical Society
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• v.34 no.1
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• pp.117-120
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• 2013

The reactions of indole with carbonyl groups have been efficiently carried out in the presence of catalytic amounts of 1,3-dibromo-5,5-dimethylhydantoin under solvent-free conditions and corresponding bis(indolyl)-mathanes were obtained in good to excellent yields. Synthesis of di[bis(indolyl)methyl]benzene was also accomplished by this catalyst. Furthermore, chemoselective conversion of aromatic aldehydes to their corresponding bis(indolyl)methanes in the presence of aliphatic aldehydes or ketones was achieved by this method.

• Journal of the Korean Chemical Society
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• v.56 no.1
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• pp.74-77
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• 2012

A new catalytic system has been developed in the synthesis of bis(indolyl)methanes using cyclic phosphonic acid anhydride(T3P). Short reaction time, simplicity of isolation, safe catalyst and high yields of product are the features.

• Bulletin of the Korean Chemical Society
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• v.26 no.12
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• pp.1962-1964
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• 2005

Zirconium(IV) chloride is found to be an efficient catalyst for the electrophilic addition reaction of indole with aldehydes/ketones to afford the corresponding bis(indolyl methanes in good yields. The remarkable features of this new procedure are high conversions, shorter reaction times, cleaner reaction profiles and simple experimental and work-up procedures.

• Archives of Pharmacal Research
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• v.26 no.1
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• pp.21-23
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• 2003

Indolyl alkaloids, $N_b-acetyltryptamine$ (1) and the known oxaline (2) have been isolated from the organic extract of the broth of an unidentified fungus collected from the surface of the marine red alga Gracilaria verrucosa. The structure of $N_{b}$-acetyltryptamine (1) was assigned on the basis of comprehensive spectroscopic analyses.s.

• Bulletin of the Korean Chemical Society
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• v.30 no.4
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• pp.825-828
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• 2009

Alum $(KAl(SO_4)_2{\cdot}12H_2O)$ is an inexpensive, efficient, non‐toxic and mild catalyst for the synthesis of bis(indolyl)methanes by the reaction of 1H-indole with various aldehydes/ketones under the influence of ultrasound irradiation in solvent‐free condition. The remarkable advantages of this method are the simple experimental procedures, shorter reaction times, high yields of product and green aspects by avoiding toxic catalysts and solvents.

• Bulletin of the Korean Chemical Society
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• v.31 no.6
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• pp.1715-1718
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• 2010

• Journal of the Korean Chemical Society
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• v.53 no.2
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• pp.202-206
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• 2009

• Bulletin of the Korean Chemical Society
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• v.27 no.6
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• pp.933-935
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• 2006

• Archives of Pharmacal Research
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• v.15 no.1
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• pp.104-108
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• 1992

2, 3-Diphenyl-6-formyl-5-methoxyindole reacts with ethyl cyano acetate to yield the arylidene derivative which forms with urea and thiourea the corresponding pyrimidine derivatives. The arylidene derivatives react with hydrazines and with active methylenes to form the respective pyrazole derivatives and the $\alpha, \;\beta$-disubstituted acrylonitriles. Seven new compounds were tested for their effects on the arterial blood pressure of rats and analgesic activity.

• Korean Journal of Plant Resources
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• v.30 no.6
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• pp.579-589
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• 2017

Glucosinolates (GSLs), beneficial secondary metabolites for human health are abundantly present in radish vegetable. Radish is a member of Brassicaceae family and its seed, leaf and root contain very important GSLs. The objective of this study was to determine the variation of individual and total GSL contents in leaves and roots of 44 radish (Raphanus spp.) germplasm (26 R. sativus L., 3 R. raphanistrum, and 15 R. sativus L. var. raphanistroides Makino), and compare the GSL contents between leaves and roots among three Raphanus species. Thirteen GSLs were identified, being the glucoraphasatin (GRS) and glucobrassicin (GBS) the most abundant aliphatic and indolyl GSLs in both the leaves and roots. Variation in individual and total GSL contents was found among the germplasm of three Raphanus species. The GRS content was higher in roots than that of leaves in all three Raphanus species but the GBS content was higher in leaves than roots. GRS was represented 87.0%, 92.7% and 94.7% of the total GSL in roots of R. sativus L., R. raphanistrum and R. sativus L. var. raphanistroides (Makino) germplasm, respectively. Germplasm of R. raphanistrum exhibited the highest (average, $79.5{\mu}mol/g\;dw$) total GSL with a ranged from 62.7 to $92.9{\mu}mol/g\;dw$. The germplasm IT119288, Joseonmu and IT119262 from R. sativus L., RA 504 and K046542 from R. raphanistrum, and Gyeongju-2003-32 (G2003-32) and IT302373 from R. sativus L. var. raphanistroides (Makino) had high total GSL contents and these could be good candidates for developing the functional compounds-rich varieties in radish breeding program.