Background: Minimal pressure support(PSmin) is a level of pressure support which offset the imposed work of breathing(WOBimp) developed by endotracheal tube and ventilator circuits in pressure support ventilation While the lower applied level of pressure support compared to PSmin could induce respiratory muscle fatigue, the higher level than PSmin could keep respiratory muscle rest resulting in prolongation of weaning period during weaning from mechanical ventilation PSmin has been usually applied in the level of 5~10 cm$H_2O$, but the accurate level of PSmin is difficult to be determinated in individual cases. PSmin is known to be calculated by using the equation of "PSmin = peak inspiratory flow rate during spontaneus ventilation$\times$total ventilatory system resistance", but correlation of calculated PSmin and measured PSmin has not been known. The objects of this study were firstly to assess whether customarily applied pressure support level of 5~10 cm$H_2O$ would be appropriate to offset the imposed work of breathing among the patients under weaning process, and secondly to estimate the correlation between the measured PSmin and calculated PSmin. Method : 1) Measurement of PSmin : Intratracheal pressure changes were measured through Hi-Lo jet tracheal tube (8mm in diameter, Mallinckroft, USA) by using pulmonary monitor(CP-100 pulmonary monitor, Bicore, USA), and then pressure support level of mechanical ventilator were increased until WOBimp was reached to 0.01 J/L or less. Measured PSmin was defined as the lowest pressure to make WOBimp 0.01 J/L or less. 2) Calculation of PSmin : Peak airway pressure(Ppeak), plateau airway pressure(Pplat) and mean inspiratory flow rate of the subjects were measured on volume control mode of mechanical ventilation after sedation. Spontaneous peak inspiratory flow rates were measured on CPAP mode(O cm$H_2O$). Thereafter PSmin was calculated by using the equation "PSmin = peak inspiratory flow rate$\times$R, R = (Ppeak-Pplat)/mean inspiratory flow rate during volume control mode on mechanical ventilation". Results: Sixteen patients who were considered as the candidate for weaning from mechanical ventilation were included in the study. Mean age was 64(${\pm}14$) years, and the mean of total ventilation times was 9(${\pm}4$) days. All patients except one were males. The measured PSmin of the subjects ranged 4.0~12.5cm$H_2O$ in 14 patients. The mean level of PSmin was 7.6(${\pm}2.5\;cmH_2O$) in measured PSmin, 8.6 (${\pm}3.25\;cmH_2O$) in calculated PSmin Correlation between the measured PSmin and the calculated PSmin is significantly high(n=9, r=0.88, p=0.002). The calculated PSmin show a tendancy to be higher than the corresponding measured PSmin in 8 out of 9 subjects(p=0.09). The ratio of measured PSmin/calculated PSmin was 0.81(${\pm}0.05$). Conclusion: Minimal pressure support levels were different in individual cases in the range from 4 to 12.5 cm$H_2O$. Because the equation-driven calculated PSmin showed a good correlation with measured PSmin, the application of equation-driven PSmin would be then appropriate compared with conventional application of 5~10 cm$H_2O$ in patients under difficult weaning process with pressure support ventilation.
This study was aimed to investigate factors that affected the status of wearing personal protective equipment (PPE) for handling poultry carcasses with potential exposure to virulent avian infectious agents. A large outbreak of high pathogenic avian influenza (HPAI) occurred in South Korea in 2014. Many public officers participated for euthanizing and handling livestock carcass. However, several safety issues with using PPE were revealed. Therefore, a questionnaire survey was conducted for 340 people who participated euthanasia and carcass disposal in the place where HPAI mainly occurred in 2014. It was found that 31.8% of the respondents had ever taken off their protective equipment during operations because of its inconvenience. The most inconvenient PPE was goggles (54.6%), followed by mask (20.2%), latex gloves (11.6%), shoe covers (5.9%) and protective clothing (5.3%). The main complaints about this individual PPE was unclear sight, damp emitted toward eye, sweating, tearing easily and sweating, respectively. Considering such problems of PPE, new possible directions for improvement of gloves and goggles were suggested. With newly developed rubber coating fabric gloves and conventionally using latex and fabric gloves, H3N2 influenza virus transmission experiment was conducted. Rubber coating fabric gloves showed similar efficiency for blocking virus transmission with latex laboratory gloves and were not easily torn by sharp claws of chicken. In addition, air flow control safety eyewear was suggested to minimize moisture formation. The air flow control system efficiently suppressed moisture formation inside the goggles. Therefore our study will provide more specific directions about new PPE development for safety protection of actual wearers.
The Journal of Korean Institute of Communications and Information Sciences
/
v.25
no.8A
/
pp.1134-1143
/
2000
We propose a scheduling algorithm, Bandwidth Allocation Scheme (BAS), that guarantees bounded delay in a switching node. It is based on the notion of the GPS (Generalized Processor Sharing) mechanism, which has clarified the concept of fair queueing with a fluid-flow hypothesis of traffic modeling. The main objective of this paper is to determine the session-level weights that define the GPS sewer. The way of introducing and derivation of the so-called system equation' implies the approach we take. With multiple classes of traffic, we define a set of service curves:one for each class. Constrained to the required profiles of individual service curves for delay satisfaction, the sets of weights are determined as a function of both the delay requirements and the traffic parameters. The schedulability test conditions, which are necessary to implement the call admission control, are also derived to ensure the proposed bandwidth allocation scheme' be able to support delay guarantees for all accepted classes of traffic. It is noticeable that the values of weights are tunable rather than fixed in accordance with the varying system status. This feature of adaptability is beneficial towards the enhanced efficiency of bandwidth sharing.
Journal of Korean Society of Industrial and Systems Engineering
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v.39
no.3
/
pp.109-117
/
2016
Recently, corporate environment is faced with uncertainty that did not suffer in the past. In addition, as the supply chain was expanded and lengthened, the flow of information and material was complicated. Increase in complexity which amplifies the variability of the individual steps in supply chains further adds to the uncertainty. The bullwhip effect that refers the phenomenon where order variability increases as the orders move upstream in the supply chain became serious. The bullwhip effect is more and more important especially for the enterprise in the supply chain. So, there are many studies now since it was observed about 100 years ago. The aim of this paper is to analyze how to solve the bullwhip effect by using TRIZ (Teoriya Resheniya Izobretatelskikh Zadach). TRIZ is one of the most famous tools for creative solving that applied in many fields ranging from management as well as engineering. Among problems, the dilemma needs creative solutions that require handling the contradictions inherent in that. Among various kinds of problem solving techniques, TRIZ provides the concept of physical contradiction as a common problem solving principle. This study provides a simple process of solving problem explains a case of solving problem in the management field and shows the availability of theory in the inventory control. In accordance with the proposed solving process, the paper analyzes the bullwhip effect by applying the TRIZ tools and then identifies the solution directions. Next, the current studies are classified by the above analysis and important managerial concepts are proposed. Lastly, directions for future research on this area are suggested.
Proceedings of the Korea Water Resources Association Conference
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2005.05b
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pp.44-51
/
2005
Water flow in rivers during flood season can be 10 to 100 fold higher than normal seasons (low precipitation) in Japan and predicting flood runoff is essential for operating reservoirs with discharging gates. Abundant experiences and knowledge are requisites for operators to be able to make efficient decisions at work. This research investigated a method to transfer technical knowledge by acquiring skills and knowledge from actual dam operators and by using the information to construct an educational training system. The purpose of the research was to enable the execution of a secure and rational reservoir operation during flood period. The educational training system for reservoir operation was developed with the focuses on acquiring knowledge on hydraulics and hydrology and learning about decision making related to the reservoir operation as well as the timing of control. The system is capable of conducting education that corresponds to individual levels in each location. Of the educational training methods, a lecture method that uses textbooks is effective for the understanding of basic knowledge and concepts while a training method that uses a simulation device is essential for the practice of advanced and specialized procedures in specific fields. Simulation devices are used in operational training for airplane flight and driving cars and trains. The educational system presented here was designed to provide further assistance to those who have acquired basic knowledge and concepts through textbooks and also to at low them to perform the satisfactory operation of dam equipment. Our research proposes a method which can realize a system to acquire technical skills-the skills which are the foundation of technical knowledge and operation.
The Transactions of the Korea Information Processing Society
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v.4
no.6
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pp.1433-1442
/
1997
Algorithm design is needed to optimized bandwidth which satisfy quality of service(QoS) requirements of vary traffic classes for Multimedia service in ATM networks. The diverse flow characteristics e.g., burstiness, bit rate and burst length, have to guarantee the different quality of service(QoS) requirements in Asynchronous Transfer Mode(ATM). The QoS parameter may be measured in terms of cell loss probability and maximum cell dely. In this paper, we consider the ATM networks which the virtual path(vip) concept is implemented by applying the Markov Modulated Deterministic Process method. We develop an efficient algorithm to computer the minimum capacity required to satisfy all the QoS requirements when multiple classes of on-off source are multiplexed on single VP. Using above the result, we propose a simple algorithm to determine the VP combination to achieve the near optimum of total capacity required for satisfying the individual QoS requirements. Numerical results are also presented to demonstrate the performance of the algorithm, when compared to the optimal total capacity required.
Objectives : This study was aimed to evaluate marker substances in Gami-Honghwa-Tang (KH-19) by high performance liquid chromatography-photodiode array detector (HPLC-DAD). Gami-Honghwa-Tang is composed of nine crude herbs, Rehmanniae Radix Preparata, Angelicae Gigantis Radix, Cnidii Rhizoma, Paeoniae Radix, Corni Fructus, Moutan Cortex Radicis, Lycii Fructus, Carthami Flos and Glycyrrhizae Radix. Methods : The separation was performed on an Aquasil C18 (4.6×250mm) column by gradient elution with 0.05% TFA in H2O - 0.05% TFA in acetonitrile (0 min 100:0, 20 min 90:10, 40 min 70:30, 60 min 50:50, 80 min 0:100, 90 min 100:0) as the mobile phase at a flow-rate of 1.0 ml/min with detection at 190-800nm. Also we examined the contents for bacteria, pesticide residue and harmful heavy metals. Results : HPLC-DAD was employed to determine the quantities and the qualities of several marker substances such as 5hydroxymethyl-2-furaldehyde (5-HMF), paeonol, loganin, paeoniflorin, glycyrrhizin, and decursin in the KH-19. There were no bacterial contents, pesticide residues, or harmful heavy metals. Conclusions : We suggest these results could be a useful evidence for quality control of KH-19. This method permits fingerprints of selected individual marker substances from herbal prescriptions without derivatization, multiple purification steps, or lengthy separation times.
Antiulcer effects of ginseng saponin, acidic polysaccharide and methanol extract of Panax ginseng in the patients and experimental animals were reported. Postulated action mechanisms of ginseng were histamine-Ht receptor blocking and increasing gastric blood flow In the present study, the effect of ginsenosides, the biologically active glycosides of ginseng, on gastric acid secretion was examined using gastric cells isolated from human and rabbit gastric mucosa. Ginseng saponin, ginsenoside $Rb_1$, $Rb_2$, $Rg_1$ and $Rh_2$ were tested in unstimulated as well as stimulated gastric cells. Histamine ($10^4$M) and 3-isobutyl-1-methylxanthine ($10^4$M) were used as secretagogues. To investigate the mechanism of ginsenosides on acid secretion, the levels of cAMP and cGMP were monitored in gastric cells. As a result, high concerltration(1mg/ml) of ginseng saponin showed 73-75% of stimulated acid secretion in control gastric cells. However, ginseng saponin had no effect on unstimulated acid secretion and the levels of cGMP and cAMP in gastric cells. Ginsenoside $Rb_1$, $Rb_2$ and $Rh_2$ significantly inhibited stimulated acid secretion. Gastric cGMP levels were increased by all ginsenosides tested while cAMP levels were increased by all ginsenosides in unstimulated state of gastric cells, but increased by ginsenosides ginsenoside $Rg_1$ and $Rh_2$in stimulated state of gastric cells. The results suggest that inhibition of ginseng saponin on gastric acid secretion represents a complex effect of individual ginsenosides, which produce a range of effect on acid secretion. The inhibition site of ginseng saponin on stimulated acid secretion is postulated as post cAMP levels in acid secretary pathway such as protein phosphorylation or proton pump. Nitric oxide may not be involved in the inhibitory effect of ginseng saponin on stimulated acid secretion.
The regulation of emission concentration for stream water qualities doesn't control quantitative increase on pollution loads, it has limits for improvement of water qualities. Total water pollution load management system(TMDL) can control the total amount of pollutant in waste water which is allowed to assign and control the total discharged pollutant loads in a permissible level. When it comes to generated wastewater value of TMDL system, there is difference between calculated value based on individual pollutant unit load and observed value. Calculated sewer inflow, calculated sewer outflow, measured sewer inflow, and measured sewer outflow at dry season are $26,460.9m^3$/d, $17,778.6m^3$/d, $17,106.1m^3$/d and $19,033.9m^3$/d respectively, Calculated sewer inflow, calculated sewer outflow, measured sewer inflow, and measured sewer outflow at rainy season are $49,512.2m^3$/d, $18,628.7m^3$/d, $30,918.2m^3$/d, $19,700.7m^3$/d respectively. This result presents the necessity to acquire the precise observed data to fulfill the efficient TMDL system.
Journal of the Institute of Convergence Signal Processing
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v.15
no.1
/
pp.15-22
/
2014
This paper presents the implementation of a control system of pellet boiler using wood pellet as carbon neutral material. The system also has the additional features to provide remote controlling and monitoring based on home networking technology through either public switched telephone networks or mobile communication networks. It consists of three kinds of sub-modules; a main controller provides basic and additional features such as a setting of temperature, a supplying of wood pellet, a controlling of ignition and fire-power, and a removing of soot. The second is temperature controller of individual rooms which is connected to the main controller through RS-485 links. And interface modules with PSTN and mobile networks can support remote controlling and monitoring the functions. The test results under the heating area of $172m^2$ show a thermal efficiency of 93.6%, a heating power of 20,640kcal/hr, and a fuel consumption of 5.54kg/hr. These results are superior to those of the conventional pellet boilers. In order to obtain the such high performance, we newly applied a 3-step ignition flow, a flame detection by $C_dS$ sensor, and a fire-power control by fine controlling of shutter to our pellet boiler.
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