• 대한치과보철학회지
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• 제50권3호
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• pp.184-190
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• 2012

연구 목적: 이 연구는 상악 전치부와 하악 구치부 치근단 방사선촬영시 이동형 구내방사선촬영기와 벽걸이 구내방사선촬영기로 촬영한 경우에서 환자의 방사선량을 알아보고자 하였다. 연구 재료 및 방법: 방사선량 측정은 선량 측정용 두경부 마네킨의 23부위에 열형광선량계 소자를 위치시키고 해당 치근단 방사선촬영을 하였다. 열형광선량계 판독기로 흡수선량을 구하였고 방사선 조사된 조직의 비율을 곱하여 방사선 가중선량을 구하였다. 국제방사선방호위원회에서 2007년에 공지한 조직 가중계수를 이용하여 각 방사선촬영의 유효선량을 구하였다. 결과: 환자의 흡수선량은 이동형 구내방사선촬영기로 촬영한 상악 전치부와 이동형 및 벽걸이 구내방사선촬영기로 촬영한 하악 구치부 치근단방사선촬영의 경우 하악체에서 가장 높았다. 유효선량은 상악 전치부 치근단 방사선촬영에서는 이동형 촬영기로 촬영한 경우 $4{\mu}Sv$, 벽걸이 촬영기로 촬영한 경우 $2{\mu}Sv$였고 우측 하악 구치부 치근단 방사선촬영에서는 각각 $6{\mu}Sv$, $2{\mu}Sv$였다. 결론: 벽걸이 구내방사선촬영기보다 이동형 구내방사선촬영기로 촬영한 치근단 방사선촬영에서의 유효선량이 더 많기 때문에 술자는 구내방사선촬영기에 따른 방사선 노출 정도를 충분히 인지하고 이를 사용하여야 한다.

• Nuclear Engineering and Technology
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• 제56권1호
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• pp.123-131
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• 2024

Electron paramagnetic resonance (EPR) dosimetry for a tooth from an individual exposed is well known as retrospective dosimetry in radiological accidents. A major constraint of the conventional X-band tooth-EPR dosimetry is the necessity to extract the tooth of the exposed patient for dose assessment. In this study, to conduct the dose assessments of exposed patients through part-extraction of tooth enamel, the minimum detectable dose (MDD) of the tooth enamel was evaluated based on the amount of mass. Further, a field test was conducted via intercomparison using various dose assessment methods to verify the feasibility of X-band tooth-EPR dosimetry using the minimum mass of tooth enamel. The intercomparison results demonstrated that effective dose determination via X-band tooth-EPR dosimetry is reliable. Consequently, it was determined that the minimum mass of tooth enamel required to evaluate an absorbed dose above 0.5 Gy is 15 mg. Thus, EPR dosimetry using 15 mg of tooth enamel can be applied in the triage and initial medical response stages for patients exposed during radiological accidents. This approach represents an advancement in managing radiological accidents by offering a more efficient and less invasive method of dose assessment.

• Journal of Radiation Protection and Research
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• 제22권4호
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• pp.299-307
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• 1997

점선원 주위에 형성되는 방사상의 감마선장에서 개인선량당량 $H_p$, 유효선량 E, 성별 유효선량 $E^m$과 $E^f$를 MIRD형 남녀 모의 피폭체를 이용하여 평가하였다. 선원은 신체의 전방 각각 15, 40 및 100 cm 거리의 여러 높이에 있는 것으로 하였고 방사성 핵종으로는 시범적으로 $^{137}Cs$과 $^{131}I$을 선정하였다. 성별 유효선량에서는 일부 예외적인 경우-예를 들면 선원이 생식선 앞에 위치할 때-를 제외하고는 대체로 여성의 경우가 크게 나타났으나, 남녀 평균값과의 차이는 크지않아 방사상 감마선장에서 성별 유효선량환산인자를 사용할 필요성은 없었다. 선량계를 가슴에서 하복부까지의 몸통 전방에 착용할 경우에는 $H_p$/E의 비가 약$1{\sim}3$의 범위에 있었고 극단적인 경우는 0.34에서 6.5까지 큰 편차를 보였다. 그러나 일반적인 방사선원 취급방법과 선량계 착용위치(흉곽 전방)를 가정하고, 선량계가 넓고 평행한 방사선장에서 유효선량에 대해 교정된다면 평행하지는 않지만 넓은 빔인 방사상 감마선장에 대해서는 용인할 수 있는 오차의 범위에서 유효선량 평가치를 제공할 수 있을 것으로 나타났다.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2003년도 가을 학술논문집
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• pp.660-664
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• 2003

연구로 1,2호기 해체과정에서 발생되는 많은 양의 금속폐기물 중 자체처분대상 금속폐기물을 대상으로 재활용하는 경우에 대해서 피폭방사선량을 평가하고, 규제해제농도기준(안)을 도출하였다. 평가도구는 ,RESRAD-RECYCLE ver 3.06을 이용하여 ICRP60에서 제시하고 있는 유효선량 개념에 근거한 내부피폭 선량환산인자를 수정하였고, IAEA Safety Series III-P-1.1 및 NUREG-1640을 적용하여 예상되는 최대개인선량 및 집단선량을 평가하였다. 0.4Bq/g의 금속폐기물에 대한 RESRAD-RECYCLE 전산코드의 평가결과 개인최대선량 및 집단선량은 23.9 ${\mu}Sv/y$, 0.11 man$\cdot$Sv/y이다. 최종적인 핵종별 규제해제농도기준은 일반평가방법과 세부평가결과를 종합하여 가장 보수적인 평가결과를 추출하여 결정하였다. 그 결과 $Co^60$, $Cs^137$ 핵종에 대한 규제해제농도준위는 $1.67{\times}10_{-1}$ Bq/g미만이 되어야 국네 원자력법에서 정하고 있는 처분제한치(최대개인선량 : 10${\mu}Sv/y$, 집단선량 : 1man$\cdot$Sv/y)를 만족할 수 있다.

• Nuclear Engineering and Technology
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• 제33권2호
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• pp.156-165
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• 2001

A radiological safety assessment was performed for a hypothetical near-surface radioactive waste repository as a simple screening calculation to identify important nuclides and to provide insights on the data needs for a successful demonstration of compliance. Individual effective doses were calculated for a conservative ground water pathway scenario considering well drilling near the site boundary. Sensitivity of resulting ingestion dose to input parameter values was also analyzed using Monte Carlo sampling. Considering peak dose rate and assessment time scale, C-14 and T-129 were identified as important nuclides and U-235 and U-238 as potentially important nuclides. For C-14, the dose was most sensitive to Darcy velocity in aquifer The distribution coefficient showed high degree of sensitivity for I-129 release.

• Journal of Radiation Protection and Research
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• 제42권4호
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• pp.205-211
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• 2017

Background: Radiation is used in a variety of areas, but it also poses potential risks. Although radiation is often used with great effectiveness in many applications, people perceive potential risks associated with radiation and feel anxious about the possibility of radiation exposure. Various methods of measuring radiation doses have been developed, but there is no way for the general public to measure their doses with ease. Currently, many people use smartphones, which provide information about the location of an individual phone through network connections. If a smartphone application could be developed for measuring radiation dosage, it would be a very effective way to measure individuals' radiation doses. Thus, we conducted a survey study to assess the social acceptance of such a technology by the general public and their intent to use that technology to measure radiation doses, as well as to investigate whether such an intention is correlated with anxiety and attitudes toward the use of radiation. Materials and Methods: A nationwide online survey was conducted among 355 Koreans who were 20 years old or older. Results and Discussion: Significant differences were found between the genders in attitudes, perceptions of radiation risk, and fears of exposure to radiation. However, a significant difference according to age was observed only in the intent to use a smartphone dose measurement application. Attitudes towards the use of radiation exerted a negative effect on radiation risk perception and exposure anxiety, whereas attitudes towards the use of radiation, risk perception, and anxiety about exposure were found to have a positive impact on the intent to use a smartphone application for dose measurements. Conclusion: A survey-based study was conducted to investigate how the general public perceives radiation and to examine the acceptability of a smartphone application as a personal dose monitoring device. If such an application is developed, it could be used not only to monitor an individual's dose, but also to contribute to radiation safety information infrastructure by mapping radiation in different areas, which could be utilized as a useful basis for radiation research.

• 방사선산업학회지
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• 제8권2호
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• pp.123-132
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• 2014

After the nuclear accident of the Fukushima Dai-ichi Nuclear Power Plants (FDNPPs) on 11 March 2011, a large amount of radioactive materials has been released into the atmosphere and the ocean. A compartment model is used to evaluate the circulation characteristics and the spatiotemporal concentration distributions of radionuclides in the ocean. In the comparison with observed concentrations of $^{137}Cs$ in seawater, calculated concentrations by the compartment model were well agreed with them. On the basis of these results, we performed evaluation of the effective dose and the cancer risk. In the early stage of the accident, the effective doses from ingestion of the seafood near the Fukushima region were much higher than 1 mSv which is the value of the annual effective dose limit to individual recommended by the International Commission on Radiological Protection (ICRP). However, the effective doses by ingestion of the seafood decreased below 1 mSv as distance from the FDNPPs increased and time passed. In addition, it was estimated that the cancer risks by intake of the contaminated marine products were less than natural occurrence probability of cancer. Consequently, it was inferred that the health risk due to the $^{137}Cs$ was low after since mid-term period of the accident.

• Asian Pacific Journal of Cancer Prevention
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• 제14권5호
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• pp.3023-3028
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• 2013

Objective: Photodynamic therapy (PDT ) is a promising modality for the treatment of various tumors. In order to assist in optimizing treatment, we applied 5-ALA/PDT in combination with low-dose cisplatin to evaluate cytotoxicity in Hela cells. Methods: Antiproliferative effects of 5-ALA/PDT and cisplatin, alone and in combination, were assessed using MTT assay. To examine levels of apoptosis, Hela cells treated with 5-ALA/PDT, and combination treatment were assessed with Annexin-V/PI by flow cytometry. To investigate the molecular mechanisms underlying alterations in cell proliferation and apoptosis, Western blot analysis was conducted to determine the expression of p53, p21, Bax and Bcl-2 proteins. Results: MTT assays indicated that combination treatment obviously decreased the viability of Hela cells compared to individual drug treatment. In addition, it was confirmed that exposure of Hela cells to 5-ALA/PDT in combination with low-dose cisplatin resulted in more apoptosis in vitro. Synergistic anticancer activity was related to upregulation p53 expression and alteration in expression of p21, Bcl-2 and Bax. Conclusion: Our findings suggest that administration of 5-ALA/PDT in combination with the low-dose cisplatin may be an effective and feasible therapy for cervical cancer.

• 한국수정란이식학회지
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• 제17권2호
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• pp.123-128
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• 2002

The present study aimed at determining the effective dose of Folltropin, a follicle timulating hormone (FSH), on superovulation in indigenous cows of Bangladesh. Fifteen regularly cycling 5～7 years old dry cows, weighing 200～250 kg with 2.5～3.0 body condition scores (BCS) were divided into three groups (n＝5). Individual groups were superovulated with 100, 200 or 300 mg of Folltropin per animal. The superovulation treatment was initiated at Day 10 or Day 11 of the estrous cycle (Day 0＝day of estrus). Alfaprostol (6 mg) was injected to each cow 72 h after the initiation of superovulation treatment to induce eestrus. After confirming standing estrus, the cows were inseminated 2～3 times, 12 h apart, depending on the duration of estrus. At Day 6 or Day 7, individual horns of the uterus were flushed with 150～200 $m\ell$ of phosphate buffered saline supplemented with BSA (0.2％), penicillin (100 IU／$m\ell$) and streptomycin (100 $\mu\textrm{g}$／$m\ell$) using a two-way foley catheter. The embryos were concentrated, removing the excess medium through an embryo filter, and identified under a stereomicroscope. The identified embryos were collected, washed four times, evaluated and graded as excellent, good, fair or poor. The excellent, good and fair embryos were considered as transferable quality embryos. The mean (range). numbers of embryos collected vs. transferable quality embryos far 100, 200 and 300 mg of Folltropin were 4.5 (1～10) vs. 3.5 (1～8); 2.5 (1～4) vs. 1 (0～2) and 0.0 (0～0) vs. 0.0 (0～0), respectively, Folltropin at a dose of 100 or 200 mg produced suitable ovarian stimulation for superovulation in indigenous zebu cows of Bangladesh. A dose of 300 mg or more Folltropin consistently caused preovulatory corpora lutea formation in the ovaries and resulted in zero embryo recovery.

• Journal of Trauma and Injury
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• 제26권3호
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• pp.198-206
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• 2013

Purpose: This study was performed to calculate and analyze the effective radiation doses from computed tomography (CT) and radiologic intervention in patients in the emergency department (ED) with trauma critical pathway (CP) activation and further to estimate the lifetime attributable risks (LARs) for the incidence of and mortality from cancers induced by the radiation dose. Methods: Through a retrospective electrical chart review of 104 injured patients who trauma critical pathway were activated from November 2012 to March 2013, we calculated effective radiologic doses by taking the product of the dose-linear product of the scan and the conversion coefficient. After a determination of the image results, we divided the patients into two groups, negative or positive, and calculated the effective dose for each group. With these results, we estimated the LARs for the incidence of and the mortality from cancers by using the table in the Biologic Effects of Ionizing Radiation (BEIR)-VII report. Results: A total of 76 patients were enrolled. The mean age was $49.0{\pm}8.5$ years. The mean injury severity score (ISS) was $12.7{\pm}8.4$. The cumulative effective dose (CED) for individual patients varied from 2.8 mSv to 238.8 mSv, and the mean was $47.6{\pm}39.9$ mSv. The CED in patients with an $ISS{\geq}16$($63.2{\pm}26.6$ mSv) was higher than that of patients whose ISS<16($33.5{\pm}23.1$ mSv) (p<0.001). The CED in patients who were treated with surgery or intervention($69.0{\pm}45.2$ mSv) was higher than that of patients who were treated conservatively($33.6{\pm}22.4$ mSv) (p<0.001). The LARs for cancer incidence and mortality were $328.5{\pm}308.6$ and $189.0{\pm}159.3$ per 100,000 people, respectively. Conclusion: The CED and the LAR for trauma CP-activated patients in the ED were significant, so efforts should be made to decrease the effective dose received by severely injured patients.