• Radiation Oncology Journal
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• 제35권1호
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• pp.48-54
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• 2017

Purpose: This study aimed to assess the effects of body mass index (BMI) on survival in cervical cancer patients who had undergone surgery and radiotherapy (RT). Materials and Methods: We retrospectively reviewed the medical records of 70 cervical cancer patients who underwent surgery and RT from 2007 to 2012. Among them, 40 patients (57.1%) had pelvic lymph node metastases at the time of diagnosis. Sixty-seven patients (95.7%) had received chemotherapy. All patients had undergone surgery and postoperative RT. Median BMI of patients was $22.8kg/m^2$ (range, 17.7 to $35.9kg/m^2$). Results: The median duration of follow-up was 52.3 months (range, 16 to 107 months). Twenty-four patients (34.3%) showed recurrence. Local failure, regional lymph nodal failure, and distant failure occurred in 4 (5.7%), 6 (8.6%), and 17 (24.3%) patients, respectively. The 5-year actuarial pelvic control rate was 83.4%. The 5-year cancer-specific survival (CSS) and disease-free survival (DFS) rates were 85.1% and 65.0%, respectively. The presence of pelvic lymph node metastases (n = 30) and being overweight or obese (n = 34, $BMI{\geq}23kg/m^2$) were poor prognostic factors for CSS (p = 0.003 and p = 0.045, respectively). Of these, pelvic lymph node metastasis was an independent prognostic factor (p = 0.030) for CSS. Conclusion: Overweight or obese cervical cancer patients showed poorer survival outcomes than normal weight or underweight patients. Weight control seems to be important in cervical cancer patients to improve clinical outcomes.

• 생약학회지
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• 제46권1호
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• pp.38-43
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• 2015

Ligularia stenocephala has a wide range of types of constituents with various pharmacological properties. Here in this study, we examined the effect of methanolic extract of L. stenocephala (MLS) on the lifespan and stress tolerance using Caenorhabditis elegans model system. We found that lifespan of wild-type worms was significantly lengthened in the presence of MLS in a dose dependent manner. MLS also elevated the tolerance of worms against osmotic, heat shock, and oxidative stress. We also demonstrated in vivo antioxidant capacity of MLS by checking intracellular reactive oxygen species levels as well as antioxidant enzyme activities such as catalase and superoxide dismutase. We further investigated several aging-related factors, including pharyngeal pumping rate and body length. Here, we showed that MLS exerts longevity effect independent of both factors. In addition, body movement of aged worms was significantly elevated, suggesting MLS could enhance healthspan as well as lifespan.

• 대한지역사회영양학회지
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• 제16권3호
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• pp.315-323
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• 2011

There are a few studies that reported the association of sleep duration with calorie intake and energy expenditure. Using cross-sectional data from a population-based prospective study, we evaluated the association of sleep duration with indicators of obesity including body mass index and waist circumference, calorie intake and its proportion of macronutrients, and physical activity. The study subjects were 4,226 male and female adults, who were aged 40 to 69 years and were free of diagnosed cardiovascular disease, diabetes mellitus, and dyslipidemia at baseline. Robust regression analysis was used to analyze associations. The study found that sleep duration is inversely associated with waist circumference, calorie intake, and percent of calories from fat intake and is positively associated with percent of calories from carbohydrate intake and physical activity. The inverse association between sleep duration and waist circumference was stronger among men than among women. The inverse association between sleep duration and calorie intake was stronger among women than among men and such association was also stronger among obese persons than those with a normal body mass index. The positive association between sleep duration and physical activity was strongly demonstrated regardless of sex or obesity. Physical activity is positively associated with sleep duration independent of potential confounding factors including age, sex, income, occupation, marital status, education, smoking status, waist circumference, calorie and macronutrient intake, and alcohol intake.

• Nuclear Engineering and Technology
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• 제27권3호
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• pp.385-392
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• 1995

월성원자력 2, 3, 4호기 safety-critical 소프트웨어에 대한 규제 기관의 요구사항을 만족시키기 위하여 소프트웨어 엔지니어링 절차가 개발되었다. 본 논문에서는 그 중에서 검증시험절차에 대하여 기술하였는데, 검증시험이란 설계그룹에서 개발된 소프트웨어가 독립된 기능그룹에서 부여한 요구사항을 모두 만족하는지를 확인하는 것이다. 이 검증시험을 수행하기 위하여 시험설비와 시험용 소프트웨어가 개발되었으며, 검증시험은 기능시험, 성능시험 및 자기점검시험 등으로 구성되었다. 시험결과를 분석하여, 불만족한 경우는 설계그룹에 통보되어 소프트웨어가 수정되었고, 최종결과는 보고서로 작성되어 규제기관에 제출될 것이다. 개발된 검증시험 방법과 절차는 효율적이고 성공적이었으며, 시험결과는 소프트웨어가 기능사양서를 충분히 만족시킨다는 것을 성공적으로 검증함을 보여주었다. 본 시험방법은 다른 safety-critical 소프트웨어 검증에도 적용될 수 있을 것이다.

• 대한정형도수물리치료학회지
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• 제23권2호
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• pp.51-57
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• 2017

Background: The purpose of this study is to examine the effects of manual therapy and therapeutic exercise on pain and body function in elder women with chronic low back pain. Methods: The patients with chronic low back pain were randomly divided 2 group. The experiment group (n=11) was taken manual therapy and therapeutic exercise program. The control group (n=10) was taken physical therapy program(hot pack with 30 minutes and ICT with 15 minutes and ultra sound with 15 minutes). Both groups intervention performed 3 session during 6 weeks. We measured the quadruple visual analogue scale, flexibility, static balance, leg strength subject of symptom before and after experiment. The significant test pared t-test according to applying the manual therapy and therapeutic exercise group and control group between group used independent t-test. Results: Pain assessment in the experimental group was significantly different between time and group. Flexibility test groups were not significantly different between time and group. The static balance was not significantly different for the time. Strength tests were also not significantly different for the time. Conclusions: According to the results, manual therapy and therapeutic exercise group it was found to be helpful in pain, flexibility, static balance, not strength in elderly patients with chronic low back pain.

• 한국직업건강간호학회지
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• 제18권1호
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• pp.44-54
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• 2009

Purpose: The aim of this study was to examine the effects of obesity on the physiological levels of adiponectin, leptin and components of metabolic syndrome (MS) in male workers, aged 30-40 years. Methods: Body mass index (BMI) was measured with Anthropometric equipment. Blood pressure and serum parameters were measured with an automatic digital sphygmomanometer and autochemical analyzer, respectively. Adiponectin and leptin were analysed by ELISA kits and MS was defined based on the NCEP-ATP III. Results: Body fat mass of waist and hip, systolic and diastolic blood pressure were significantly higher, as expected, in the BMI>25kg/$m^2$ in comparison with the $BMI{\leq}25kg/m^2$. While fasting glucose, insulin, HOMA-IR and leptin in the BMI>25kg/$m^2$ were also significantly higher compared with $BMI{\leq}25kg/m^2$, HDL-cholesterol and adiponectin were significantly higher in $BMI{\leq}25kg/m^2$. On multiple logistic regression analysis for the components of MS, exercise, adiponectin and leptin were an only independent factor for MS in non-obese male workers($BMI{\leq}25kg/m^2$) after adjustment for age, cigarette smoking and drinking habits. Conclusion: These results suggested that the obesity in men was associated with physiological levels of adiponectin and leptin contributing to feedback control of MS and that dysfunction and/or declination in feedback control system associated with changes in physiological levels of neurptrophics: adiponectin and leptin might ultimately induce MS.

• 한국조경학회지
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• 제29권2호
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• pp.22-31
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• 2001

The purpose of this paper is to investigate in resources of natural recreation forest(RNRF) developed both publicly and privately in order to answer the research question: what are the differences in RNRF development between public and private developers. After reviewing the literature, the developer´s decision-making and motivation of investment, and the planning process of natural recreation forest, We constructed the conceptual framework and have formulated the hypothesis of this research. We had obtained data through a questionnaire, which surveyed of 625 visitors at 9 of the 72 natural recreation forests in Korea in 1999, We have analyzed the data using the mean difference test and logistic regression method. We found that 1) the overall quality of resource elements in RNRF has been development excellent except for the sociocultural element of recreational resources, and public recreation forest have been of higher quality than that fo private development, 20 in bivariate analysis, all the variables on quality of RNRF by public developers have turned out to be better than those of private ones, 3) in multivariate analysis, such variable as valley and water, forest and wildness area, wild life, and landscape have been statistically significant at one percent level, 4) the higher the value of valley and water, the higher the probability of public development, while the higher the value of other variables excluding water and valley, the more likelihood the recreational forest is developed by a private developer, and 5) forest and wildness area has been turned out to be the most important independent variable in contributing to the value of dependent variable. The research results suggest that 1) the differences in the quality of resource elements in RNRF developed by public and private body be considered in the planning and design process in order to develop diverse activities to make use of the resource potential, and 2) considering the resource characteristics of private natural recreation forest and the motivation of private developers, private natural recreation forest will possibly be more dynamic and dynamic attractive areas. It is recommended that the difference in the degree of visitor´s satisfaction between public and private development be examined.

• 디지털콘텐츠학회 논문지
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• 제18권3호
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• pp.543-550
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• 2017

슈퍼 히어로 영화는 모든 세대를 아우를 수 있는 새로운 장르 컨벤션을 형성하였다. 영상콘텐츠에서 파생된 피규어는 전문적인 조형기술을 통해 제작된 입체 조형물이다. 피규어에 대한 소유는 가상과 현실을 연결시켜 주는 매개체로써 상징적 의미를 가진다. 이러한 관점에서 피규어는 콘텐츠 산업의 시장 확장에 따른 파생된 캐릭터 상품으로써 중요한 부분을 차지한다. 이러한 맥락에서 본 연구는 슈퍼히어로 피규어의 외형적 시각요소 평가가 구매의도에 어떠한 영향을 미치는가를 분석함으로써 소비자구매형태를 확인하는 것이 그 목적이다. 이를 위해 독립변인을 캐릭터의 외형적 시각요소 평가로써 색상, 신체유형, 얼굴모양, 동작으로, 종속변인은 구매의도로 하여 다중회귀분석을 실시하였다. 분석결과, 색상, 신체유형, 얼굴모양은 구매의도에 긍정적 영향을 미치는 것으로 나타났고, 동작은 구매의도에 유의미한 영향력이 없는 것으로 나타났다.

• Journal of the Korean Data and Information Science Society
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• 제25권5호
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• pp.1025-1038
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• 2014

가족 자료를 활용한 연속형 표현형의 전장유전체분석 (genome-wide association analysis)은 주로 선형혼합모형을 이용하며, 분산공분산행렬은 가족 구성원간의 유전적 거리를 고려하여 결정된다. 그러나 가족 구성원들의 표현형의 유사성은 유전적 요인과 환경적 요인에 의하여 발생함에도 불구하고, 표현형의 유사성은 단지 유전적 요인에 의해서 발생한다고 가정한다. 예를 들어 키의 경우 부부 사이에 양의 상관관계가 존재하나 유전적 요인만 고려하여 독립으로 가정한다. 선형혼합 모형에서 분산공분산 구조를 잘못 가정하는 경우, 검정통계량의 1종 혹은 2종의 오류를 적절히 관리할 수 없다. 본 논문에서는 다양한 유형의 분산공분산구조를 가정할 수 있는 선형혼합모형과 이를 기반으로 한 검정통계량을 제안하였다. 모의실험을 통하여 제안한 방법이 기존의 모형보다 통계적 검정력이 우수함을 확인하였다. 또한 체질량지수 (body mass index; BMI)의 전장유전체 분석에 적용하여 기존에 알려지지 않은 새로운 원인 유전자를 규명하였다.

• 한국의류학회지
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• 제33권9호
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• pp.1361-1373
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• 2009

This study analyzed female motives and psychological experiences related with high-heeled shoes. Data was collected through in-depth interviews with seven females having more than forty pairs of high-heeled shoes. Exploratory data are classified into physical aspects and mental aspects, and the meaning of wearing high-heeled shoes were derived and discussed. First, with high-heeled shoes, the participants tried to make an ideal physical appearance, 1) to make an aesthetic illusion of a longer, more slender body 2) to make a more glamorous bodyline and toned legs. Second, the psychological experiences were as follows: 1) Wearing high-heeled shoes, they felt self-confidence in appearance and had feelings of satisfaction, fulfillment, and superiority. 2) High-heeled shoes gave wearers an increased sexual appearance in addition to a feminine attitude and independent mind. Accordingly, wearers thought they could make males compliant with a better sexual look in private and public life. 3) Through buying or putting on high-heeled shoes, women could change their mood, have mental stability, and channel sexual desires. 4) Some women made the secret self with the collected high-heeled shoes for sexual fantasies. 5) They thought that painful bodies or feet were not cumbersome. In addition, some wearers thought high-heeled shoes were a natural extension of their bodies.