Lifespan Extending Effects of Ligularia stenocephala
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Kim, Sang Hyun
(College of Pharmacy, Woosuk University)
Im, Jun Sang (College of Pharmacy, Woosuk University) Kim, Bong Seok (College of Pharmacy, Woosuk University) Lim, Hyun Ju (College of Pharmacy, Woosuk University) Oh, Jong Woo (College of Pharmacy, Woosuk University) Park, Jin Suck (College of Pharmacy, Woosuk University) Yoon, Young Jin (College of Pharmacy, Woosuk University) Lee, Ha Na (College of Pharmacy, Woosuk University) Cha, Dong Seok (College of Pharmacy, Woosuk University) Jeon, Hoon (College of Pharmacy, Woosuk University) |
1 | Kampkotter, A., Gombitang Nkwonkam, C., Zurawski, R. F., Timpel, C., Chovolou, Y., Watjen, W. and Kahl, R. (2007) Effects of the flavonoids kaempferol and fisetin on thermotolerance, oxidative stress and FoxO transcription factor DAF-16 in the model organism caenorhabditis elegans. Arch. Toxicol. 81: 849-858. DOI |
2 | Collins, J. J., Evason, K. and Kornfeld, K. (2006) Pharmacology of delayed aging and extended lifespan of caenorhabditis elegans. Exp. Gerontol. 41: 1032-1039. DOI |
3 | Petrascheck, M., Ye, X. and Buck, L. B. (2007) An antidepressant that extends lifespan in adult caenorhabditis elegans. Nature 450: 553-556. DOI |
4 | Kenyon, C. J. (2010) The genetics of ageing. Nature 464: 504-512. DOI |
5 | Partridge, L., Gems, D. and Withers, D. J. (2005) Sex and death: What is the connection? Cell 120: 461-472. DOI |
6 | Brenner, S. (1974) The genetics of Caenorhabditis elegans. Genetics 77: 71-94. |
7 | Lakowski, B. and Hekimi, S. (1998) The genetics of caloric restriction in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 95: 13091-13096. DOI |
8 | Herndon, L. A., Schmeissner, P. J., Dudaronek, J. M., Brown, P. A., Listner, K. M., Sakano, Y., Paupard, M. C., Hall, D. H. and Driscoll, M. (2002) Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 419: 808-814. DOI |
9 | Glenn, C. F., Chow, D. K., David, L., Cooke, C. A., Gami, M. S., Iser, W. B., Hanselman, K. B., Goldberg, I. G. and Wolkow, C. A. (2004) Behavioral deficits during early stages of aging in Caenorhabditis elegans result from locomotory deficits possibly linked to muscle frailty. J. Gerontol. A Biol. Sci. Med. Sci. 59: 1251-1260. DOI |
10 | Lithgow, G. J., White, T. M., Melov, S. and Johnson, T. E. (1995) Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc. Natl. Acad. Sci. U. S. A. 92: 7540-7544. DOI |
11 | Horikawa, M. and Sakamoto, K. (2009) Fatty-acid metabolism is involved in stress-resistance mechanisms of caenorhabditis elegans. Biochem. Biophys. Res. Commun. 390: 402-1407. DOI |
12 | Mekheimer, R. A., Sayed, A. A. and Ahmed, E. A. (2012) Novel 1,2,4 ñ triazolo [1,5-a] pyridines and their fused ring systems attenuate oxidative stress and prolong lifespan of caenorhabiditis elegans. J. Med. Chem. 55: 4169-4177. DOI ScienceOn |
13 | Ibrahim, H. R., Hoq, M. I. and Aoki, T. (2007) Ovotransferrin possesses SOD-like superoxide anion scavenging activity that is promoted by copper and manganese binding. Int. J. Biol. Macromol. 41: 631ñ640. DOI |
14 | Aebi, H. (1984) Catalase in vitro. Methods Enzymol. 105: 121-126. DOI |
15 | Lee, B. I., Nugroho, A., Bachri, M. S., Choi, J., Lee, K. R., Choi, J. S., Kim, W. B., Lee, K. T., Lee, J. D. and Park, H. J. (2010) Anti-ulcerogenic effect and HPLC analysis of the caffeoylquinic acid-rich extract from Ligularia stenocephala. Biol. Pharm. Bull. 33: 493-497. DOI |
16 | Toyoda, K,, Yaoita, Y. and Kikuchi, M. (2005) Three new dimeric benzofuran derivatives from the roots of Ligularia stenocephala MATSUM. et KOIDZ. Chem. Pharm. Bull. 53: 1555-1558. DOI |
17 | Harrington, L. A. and Harley, C. B. (1988) Effect of vitamin E on lifespan and reproduction in Caenorhabditis elegans. Mech. Ageing Dev. 43: 71-78. DOI ScienceOn |
18 | Yaoita, Y., Kikuchi, M., and Machida, K. (2012) Terpenoids and relatedcompounds from plants of the family Compositae (Asteraceae). Nat. Prod. Commun. 7: 533-538. |
19 | Yan, F. L., Wang, A. X. and Jia, Z. J. (2005) Three new polymeric isopropenyl benzofurans from Ligularia stenocephala. Pharmazie 60: 155-159. |
20 | Tazearslan, C., Ayyadevara, S., Bharill, P. and Shmookler Reis, R. J. (2009) Positive feedback between transcriptional and kinase suppression in nematodes with extraordinary longevity and stress resistance. PLoS Genet. 5: e1000452. DOI |
21 | Golden, T. R. and Melov, S. (2007) Gene expression changes associated with aging in C. elegans. WormBook 1-12. DOI |
22 | Antebi, A. (2007) Ageing: when less is more. Nature 447: 536-537. DOI |
23 | Brown, M. K., Evans, J. L. and Luo, Y. (2006) Beneficial effects of natural antioxidants EGCG and alpha-lipoic acid on life span and age-dependent behavioral declines in Caenorhabditis elegans. Pharmacol. Biochem. Behav. 85: 620-628. DOI ScienceOn |
24 | Oliveira, B. F., Nogueira-Machado, J. A. and Chaves, M. M. (2010) The role of oxidative stress in the aging process. Scientific World Journal 10: 1121-1128. DOI ScienceOn |
25 | Guarente, L. and Kenyon, C. (2000) Genetic pathways that regulate ageing in model organisms. Nature 408: 255-262. DOI ScienceOn |
26 | Bokov, A., Chaudhuri, A. and Richardson, A. (2004) The role of oxidative damage and stress in aging. Mech. Ageing Dev. 125: 811-826. DOI |
27 | Finkel, T. and Holbrook, N. J. (2000) Oxidants, oxidative stress and the biology of ageing. Nature 408: 239-247. DOI |
28 | Wu, Z., Smith, J. V., Paramasivam, V., Butko, P., Khan, I., Cypser, J. R. and Luo, Y. (2002) Ginkgo biloba extract EGb 761 increases stress resistance and extends life span of Caenorhabditis elegans. Cell. Mol. Biol. (Noisy-le-grand) 48: 725-731. |
29 | Ishii, N., Senoo-Matsuda, N., Miyake, K., Yasuda, K., Ishii, T., Hartman, P. S. and Furukawa, S. (2004) Coenzyme Q10 can prolong C. elegans lifespan by lowering oxidative stress. Mech. Ageing Dev. 125: 41-46. DOI |
30 | Adachi, H. and Ishii, N. (2000) Effects of tocotrienols on life span and protein carbonylation in Caenorhabditis elegans. J. Gerontol. A Biol. Sci. Med. Sci. 55: B280-285. DOI |
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