• Journal of Gastric Cancer
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• 제11권1호
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• pp.7-15
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• 2011

Osteoporosis in gastric cancer patients is often overlooked or even neglected despite its high prevalence in these patients. Considering that old age, malnutrition, chronic disease, chemotherapy, decreased body mass index and gastrectomy are independent risk factors for osteoporosis, it is reasonable that the prevalence of osteoporosis in gastric cancer patients would be high. Many surviving patients suffer from back pain and pathological fractures, which are related to osteoporosis. Fractures have obvious associated morbidities, negative impact on quality of life, and impose both direct and indirect costs. In the era of a >55.6% 5-year survival rate of gastric cancer and increased longevity in gastric cancer patients, it is very important to eliminate common sequelae such as osteoporosis. Fortunately, the diagnosis of osteoporosis is well established and many therapeutic agents have been shown to be effective and safe not only in postmenopausal females but also in elderly males. Recently, effective treatments of gastric cancer patients with osteoporosis using bisphosphonates, which are commonly used in postmenopausal woman, were reported.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 춘계학술대회 논문집
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• pp.652-655
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• 2003

This paper is about the recent development of the magnetic impact actuator for endoscope. The developed magnetic impact actuator has many problems to arrange in the system body. Because the magnetic impact actuator need a permanent magnet as an impacter, so the magnetic interference among magnets can not be eliminated. This interference causes the system size bigger. We need a new actuator design to solve these problems. One of the good solutions is to use the closed electro-magnetic circuit. This kind of circuit enhances the actuators to be independent. It is written about the design of the electro-magnetic circuit and simulation using Maxwell(version 9.0)

• 생약학회지
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• 제33권4호통권131호
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• pp.332-336
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• 2002

Opuntia ficus-indica var. sabotan was administered with diet for 5 weeks on db/db diabetic mice and its antidiabetic activity was investigated. Leaves of Opuntia ficus-indica var. sabotan inhibited the increase of body weight, glucose elevation in blood and urine, and protein excretion in urine, and protein excretion in urine. Opuntia ficus-indica var. sabotan also inhibited the intestinal maltase and sucrase activity on db/db Mice loaded with maltose and sucrose. However, it did not significantly lower HbAlc in blood of db/db mice. These results suggest that leaves of Opuntia ficus-indica var. sabotan could be effective on insulin-independent diabetic mellitus type 2.

• 한국주거학회논문집
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• 제14권5호
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• pp.117-128
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• 2003

The purpose of this study is to investigate the effect of functional ability on relocation among the elderly. Longitudinal data from the Asset and Health Dynamics among the Oldest Old (1993, 1995) were analyzed for 6,225 respondents aged 70 or older. Among functional ability measures, difficulties in advanced activities of daily living (i. e., making telephone calls, taking medications, and managing money), lower body activities (i. e., walking several blocks, climbing one flight of stairs, pulling or pushing large objects, and carrying over 10 pounds), and household activities of daily living (i. e., preparing hot meals and shopping for groceries) were the predictors of increased residential move. Difficulties in basic activities of daily living (i. e., bathing, dressing, getting in and out, and using the toilet) were strongly related to increased entrance into an institutional care facility. Efforts to enhance the independent living of the elderly in the community setting should target the compensation of these functional difficulties.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2011년 춘계학술대회논문집
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• pp.78-85
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• 2011

The Vortex-In-Cell(VIC) method combined with panel method is applied to the analysis of incompressible unsteady viscous flow. The dynamics of resulting flow is governed by the vorticity transport equation in Lagrangian form with vortex particle representation of the flow field. A regular grid which is independent to the shape of a body is used for numerical evaluation based on immersed boundary technique. With an introduction of this approach, the development and validation of the VIC method is presented with some computational results for incompressible viscous flow around two or three dimensional bodies such as wing section, sphere, finite wing and marine propeller.

• 한국정보통신학회논문지
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• 제10권3호
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• pp.599-607
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• 2006

여러 형태의 Tonal 신호로 나타내어지는 선박 수중방사소음 원인을 효율적으로 분류하기 위해서 Tonal 신호를 잡음으로부터 분리하고 임계값을 초과하는 Tonal 신호를 자동으로 추출하였다. 추출된 신호의 발생기원이 속력 종속적인지 속력 비종속적인지 여부를 Q factor및 신경회로망의 패턴인식 기법을 이용하여 자동으로 판별하는 알고리즘을 제안하였다. 또한, 수치 시뮬레이션 및 실제 수중에서 측정된 선박소음에 적용하여 제안된 알고리즘의 유용성 여부에 대하여 검토하였다.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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• pp.121.2-121.2
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• 2014

Synthesis of catecholamine from aniline is achieved by plasma enhanced CVD process. Catecholamine has a variety of functions in body such as brain and bloodstream controls. Catecholamine also has an interesting property of a material independent ability of functionalizing surface, which is found at mussels' adhesive nature. Synthesis of catecholamine has only been available from DOPA by chemical reduction and oxidation. This study presents the direct synthesis of catecholamine from further elemental source, aniline, which has not been achieved by a conventional chemical method. The process also indicates that a variety of catecholamine can be formed by controlling reactant gases. In additional to PECVD's very useful properties such as conformal, ultrathin and uniform coatings, a direct synthesis from aniline and a capability of controlling formation of a variety catecholamine is believed to open up a numerous applications.

• 소성∙가공
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• 제17권3호
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• pp.161-169
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• 2008

In the present work, the two-back stress model is proposed and continuum damage mechanics (CDM) is incorporated into the plastic constitutive relation in order to describe the plastic deformation localization and the damage evolution in a deforming continuum body. Coupling between damage mechanics and isothermal rate independent plasticity is performed using the kinematic hardening rule, which in turn is formulated by combining the nonlinear Armstrong-Frederick rule and the Phillips rule. The numerical analyses are carried out within h deformation theory. It is noted that the damage evolution within a work piece accelerates the plastic deformation localization such that the material with lower hardening exponent results in a rapid shear band formation. Moreover, the results from the numerical analysis reflected closely with the micro-structures around the fractured regime. The effects of the various hardening parameters on deformation localization are also investigated. As the nonlinear strain rate description in the back stress evolution becomes dominant, the strain localization becomes intensified as well as the damage evolution.

• Asia pacific journal of information systems
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• 제22권1호
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• pp.79-101
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• 2012

This study expands the current body of research by exploring multiple scenarios of insufficient and excessive IT security investments caused by interdependent risks and the interplay between IT security investments and cyber insurance. A key finding is that organizations experiencing interdependent risks with different types of cyber attacks (i.e., targeted and untargeted attacks) use different strategies in making IT security investment decisions and in purchasing cyber insurance policies for their information security risk management than firms that are facing independent risks. The study further provides an economic rationale for employing insurance mechanisms as a risk management solution for information security.

• Molecules and Cells
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• 제39권12호
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• pp.847-854
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• 2016

The early landmark discoveries in cancer metabolism research have uncovered metabolic processes that support rapid proliferation, such as aerobic glycolysis (Warburg effect), glutaminolysis, and increased nucleotide biosynthesis. However, there are limitations to the effectiveness of specifically targeting the metabolic processes which support rapid proliferation. First, as other normal proliferative tissues also share similar metabolic features, they may also be affected by such treatments. Secondly, targeting proliferative metabolism may only target the highly proliferating "bulk tumor" cells and not the slowergrowing, clinically relevant cancer stem cell subpopulations which may be required for an effective cure. An emerging body of research indicates that altered metabolism plays key roles in supporting proliferation-independent functions of cancer such as cell survival within the ischemic and acidic tumor microenvironment, immune system evasion, and maintenance of the cancer stem cell state. As these aspects of cancer cell metabolism are critical for tumor maintenance yet are less likely to be relevant in normal cells, they represent attractive targets for cancer therapy.