• 제목/요약/키워드: Incubation program

검색결과 77건 처리시간 0.018초

Dot Idea (.IDEA): A New Concept for an Incubation Program and Open Innovation Based on User Needs

  • Maldaner, Luis Felipe;Simon, Luisa;Aranha, Carlos Eduardo de Souza
    • World Technopolis Review
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    • 제7권2호
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    • pp.82-96
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    • 2018
  • This paper discussed the application process of the Dot Idea program. The Dot Idea program is an incubation and open innovation program co-created by Unitec, an incubator at Tecnosinos Tech Park, and an SAP innovation team. The main objective of this study was to cover an existing gap in the literature regarding the practical application of an open innovation methodology. Many companies seek interaction with external parties to enable advancement toward identified innovation opportunities. Technology clusters, parks, and incubators have played an important role in promoting connections and interaction. Consequently, the Dot Idea program emerged as a result of a joint effort to create a program using a design science research methodology aiming to foster new businesses and strengthen Brazil and Latin America as a hub to develop new solutions for traditional organizations. In regards to lessons learned, the Dot.health trial had some success but also experienced difficulties; these related to the relationships between startups and a hospital's internal teams, and startups' needs to be funded from the beginning in order to be fully dedicated to a project.

액셀러레이터 보육프로그램과 보육기업의 창업성과 : 액셀러레이터 창업가 열정의 조절효과 중심으로 (Accelerator Incubation Program and Entrepreneurial Performance of Portfolios : Focusing on the Moderating Effect of Accelerator Entrepreneur Passion)

  • 김상철;정병규
    • 벤처혁신연구
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    • 제5권3호
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    • pp.1-17
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    • 2022
  • 창업가는 본인의 열정이 창업을 성공적으로 이끄는 중요한 요인이라는 것을 인식하고 있다. 하지만 그들은 창업과 관련된 제3자의 열정이 본인에게 미치는 영향에 대해서는 제대로 인식하지 못하고 있는 경우가 많다. 이에 본 연구에서는 액셀러레이터 보육프로그램이 보육기업에 효과적인 영향을 주는지를 검증하였다. 이때 제3자인 액셀러레이터 창업가 열정이 보육기업의 창업성과에 어떠한 영향을 미치는지에 초점을 두고 실증적으로 분석을 하고자 했다. 이를 위해 액셀러레이터 보육프로그램을 수료한 전국의 보육기업 대표자를 대상으로 설문조사를 하였고 유효한 330개를 토대로 실증적으로 검증하였다. 실증분석 결과, 액셀러레이터 보육프로그램 중 멘토링과 네트워크는 스타트업의 창업성과에 정(+)의 영향을 미치는 것이 확인되었다. 반면 액셀러레이터 보육프로그램 중 교육과 초기투자는 스타트업의 창업성과에 유의한 영향을 미치지 않았다. 한편, 액셀러레이터 창업가 열정이 보육프로그램 요소(교육, 멘토링, 네트워크, 초기투자)와 보육기업의 창업성과 간을 모두 유의하게 조절하고 있다는 것이 검증되었다. 본 연구 결과는 스타트업에 있어서 액셀러레이터 창업가 열정이 보육프로그램의 중요한 린치핀이며 성공의 열쇠라는 사실을 밝힌 점에서 의미가 있다. 또한 본 연구는 스타트업이 시드 투자에서 한 걸음 더 나아가 액셀러레이터의 키맨인 액셀러레이터 창업가와 그의 열정을 제대로 확인하는 것이 중요하다는 점을 제시한다.

Effects of Cordyceps militaris Mycelia on In vitro Rumen Microbial Fermentation

  • Yeo, Joon Mo;Lee, Shin Ja;Lee, Sang Min;Shin, Sung Hwan;Lee, Sung Hoon;Ha, Jong K.;Kim, WanYoung;Lee, Sung Sill
    • Asian-Australasian Journal of Animal Sciences
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    • 제22권2호
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    • pp.201-205
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    • 2009
  • Effects of Cordyceps militaris mycelia on rumen microbial fermentation were determined by measuring in vitro gas production, cellulose digestion and VFA concentrations. C. militaris mycelia was added to buffered rumen fluid with final concentrations of 0.00, 0.10, 0.15, 0.20, 0.25 and 0.30 g/L and incubation times were for 3, 6, 9, 12, 24, 36, 48 and 72 h. At all incubation times, the gas production showed a quadratic increase with the supplementation of C. militaris mycelia; maximum responses were seen with 0.25 g/L supplementation. However, the gas production was significantly lower for the 0.30 g/L supplementation than for the 0.25 g/L supplementation from 9 h to 72 h incubation. The cellulose filter paper (FP) digestion showed a quadratic increase, as did the gas production except at 3 h incubation. The concentration of total VFA was significantly increased by the supplementation of C. militaris mycelia compared with the control treatment; the highest response was also seen with 0.25 g/L supplementation. This was true for responses in the concentration of acetic and propionic acids. As opposed to other responses, the responses of pH to the supplementation of C. militaris mycelia showed a quadratic decrease from 3 h to 36 h incubation. In conclusion, C. militaris mycelia alter the mixed rumen microbial fermentation with increases in the production of gas and VFA, and cellulose FP digestion.

반추동물의 에너지 손실을 줄이기 위한 연구; 무 추출물을 이용한 메탄 손실 억제 (Reduce the Energy Loss in Ruminant; Using Raphanus Sativus Extracts to Mitigate Methane Emission)

  • 이신자;최유영;이수경;이일동;엄준식;김현상;김도형;이성실
    • 한국유기농업학회지
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    • 제25권4호
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    • pp.917-930
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    • 2017
  • This study was conducted to evaluate Raphanus sativus extracts to methane reduction in rumen. Five different levels of R. sativus extracts were used to investigate the most effective dosing level for the decrease of methane production in the rumen. The rumen fluid was collected from a cannulated one Hanwoo cow ($BW=450{\pm}30kg$) consuming 600 g/kg timothy and 400 g/kg concentrate. On fermentation day, rumen fluid was collected at 2 hr postfeeding R. sativus extracts was dosed to achieve final concentration of 0, 1, 3, 5, 7, and 9% respectively, to fermentation bottles containing the mixture of rumen fluid and McDougall's buffer and 300 mg of timothy was added as a substrate. The fermentation was conducted for 3, 6, 9, 12, 24, 48 and 72 hr incubation time at $39^{\circ}C$ with shaking. In vitro ruminal pH values were measured normal range for ruminal fermentation. Dry matter disappearance was significantly higher (p<0.05) at 3 hr incubation time 1, 3 and 5% doses than that of control. The highest methane reduction was observed in 12 hr incubation time 5, 7 and 9%. The carbon dioxide emission was also significantly (p<0.05) lower than that of control at 12 hr incubation time 5, 7 and 9%. The total volatile fatty acid was no significant difference between control and all doses level at 12 and 24 hr incubation time. At 24 hr incubation time, the result of real-time PCR were indicated that M. archea was significantly lower (p<0.05) at all doses level comparing to that of control. In conclusion, R. sativus extracts were significantly decreased methane emission. R. sativus extracts were significantly lower (p<0.05) than that of control at 12 hr incubation time 5, 7 and 9% and no adversely effect in rumen pH, dry matter disappearance and total VFA.

Effects of Cordyceps militaris Mycelia on Fibrolytic Enzyme Activities and Microbial Populations In vitro

  • Yeo, Joon-Mo;Lee, Shin-Ja;Shin, Sung-Hwan;Lee, Sung-Hoon;Ha, Jong-Kyu;Kim, Wan-Young;Lee, Sung-Sill
    • Asian-Australasian Journal of Animal Sciences
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    • 제24권3호
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    • pp.364-368
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    • 2011
  • An experiment was conducted to examine the effects of Cordyceps militaris mycelia on microbial populations and fibrolytic enzyme activities in vitro. C. militaris mycelia was added to buffered rumen fluid with final concentrations of 0.00, 0.10, 0.15, 0.20, 0.25 and 0.30 g/L and incubation times were for 3, 6, 9, 12, 24, 36, 48 and 72 h. At all incubation times, the supplementation of C. militaris mycelia linearly increased the number of total viable and celluloytic bacteria; maximum responses were seen with 0.25 g/L supplementation of C. militaris mycelia. The addition of C. militaris mycelia above the level of 0.20 g/L significantly (p<0.01) increased the number of total and cellulolytic bacteria compared with the control. On the other hand, the response of fungal counts to the supplementation of C. militaris mycelia showed a linear decrease; the lowest response was seen with 0.30 g/L supplementation of C. militaris mycelia. It would seem that C. militaris mycelia possess a strong negative effect on rumen fungi since the lowest level of C. militaris mycelia supplementation markedly decreased fungal counts. Carboxylmethyl cellulase activities were linearly increased by the addition of C. militaris mycelia except at 3 and 9 h incubation times. At all incubation times, the supplementation of C. militaris mycelia linearly increased the activities of xylanase and avicelase. In conclusion, the supplementation of C. militaris mycelia to the culture of mixed rumen microorganisms showed a positive effect on cellulolytic bacteria and cellulolytic enzyme activities but a negative effect on fungi.

Heterologous Gene Expression of aprE2 Encoding a 29 kDa Fibrinolytic Enzyme from Bacillus subtilis in Bacillus licheniformis ATCC 10716

  • Kwon, Gun-Hee;Jeong, Woo-Ju;Lee, Ae-Ran;Park, Jae-Yong;Cha, Jae-Ho;Song, Young-Sun;Kim, Jeong-Hwan
    • Food Science and Biotechnology
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    • 제17권6호
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    • pp.1372-1375
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    • 2008
  • The aprE2 gene from Bacillus subtilis CH3-5 was expressed in Bacillus licheniformis ATCC 10716 using a Bacillus-Escherichai coli shuttle vector, pHY300PLK. The fibrinolytic activity of transformant (TF) increased significantly compared to B. licheniformis 10716 control cell. During the 100 hr incubation in Luria-Bertaini broth at $37^{\circ}C$, fibrinolytic activity of B. licheniformis TF increased rapidly at the late growth stage, after 52 hr of incubation, which was confirmed by zymography using a fibrin gel. pHY3-5 was stably maintained in B. licheniformis without tetracycline (Tc) in the media, 60.9% of cells still maintained pHY3-5 after 100 hr of cultivation.

액셀러레이터 보육프로그램과 창업자기효능감이 경쟁우위성과에 미치는 영향 연구 : 혁신역량의 매개효과를 중심으로 (A Study on the Effects of Accelerator Incubation Program and Entrepreneur Self-Efficacy on Competitive Advantage Performance : Focusing on the Mediating Effect of Innovation Competence)

  • 장석조;현병환
    • 벤처혁신연구
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    • 제6권3호
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    • pp.1-20
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    • 2023
  • 본 연구는 액셀러레이터 보육프로그램을 경험한 스타트업 대표자를 대상으로, 액셀러레이터 보육프로그램(멘토링, 초기투자)와 창업자기효능감이 경쟁우위성과에 영향을 주는지 실증분석을 하였고, 이때 혁신역량의 매개효과도 함께 살펴보았다. 표본의 수집은 전국 액셀러레이터, 창조경제혁신센터 등이 보육한 스타트업 대표자 대상으로 수집한 334건의 표본을 Smart PLS 4.0 프로그램을 사용하여 가설을 검정하였으며, 분석 결과는 다음과 같다. 첫째, 멘토링은 경쟁우위성과에 유의한 영향을 미치지 않지만, 초기투자와 창업자기효능감은 경쟁우위성과에 정(+)의 영향을 미치는 것으로 나타났다. 둘째 멘토링, 초기투자, 창업자기효능감은 혁신역량에 정(+)의 영향을 미치는 것으로 나타났다. 셋째, 혁신역량은 경쟁우위성과에 정(+)의 영향을 미치는 것으로 나타났다. 넷째, 혁신역량은 멘토링, 초기투자, 창업자기효능감과 경쟁우위성과 간에 정(+)의 영향을 미치며, 매개효과가 있음을 확인하였다. 결과적으로 멘토링은 경쟁우위성과에 직접적으로 유의한 영향을 주지 않지만, 혁신역량을 매개로 하여 유의한 영향이 있음을 확인되었으며, 초기투자, 창업자기효능감, 혁신역량은 경쟁우위성과에 직접적으로 도움이 되는 것으로 나타났고, 혁신역량이 매개 작용으로 경쟁우위성과에 영향 관계가 있음을 확인하였다. 본 연구를 통하여 스타트업의 경쟁우위성과를 높이는 데 도움이 될 수 있는 방향을 제시할 수 있을 것으로 기대된다.

Technology Transfer and Entrepreneurial Development through University Business Incubation Process in Thailand

  • Wonglimpiyarat, Jarunee
    • World Technopolis Review
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    • 제3권2호
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    • pp.78-88
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    • 2014
  • This study is concerned with the process of technology transfer and commercialization. It is focused on the entrepreneurial development through the university business incubation process of Thailand. The study analyzes the leading university business incubators (UBIs) as well as major science and technology incubators to understand the strategies for commercialization of technology. The analyses of results, based on the Triple Helix model, have shown that the incubation program is one of the major policy mechanisms to support innovation and suggested that UBIs should act as an intermediary between the spheres of university and industry to provide interactive linkages and promote effective utilization of university research. The empirical study provides theoretical and managerial implications on the government policies to support the entrepreneurial development, innovation development and diffusion.

시설재배지 토양에서 유기자재 투입이 염류활성도에 미치는 영향 (Effect of Organic Residue Incorporation on Salt Activity in Greenhouse Soil)

  • 이슬비;이창훈;홍창오;김상윤;이용복;김필주
    • 한국환경농학회지
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    • 제28권4호
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    • pp.397-402
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    • 2009
  • In Korea, salt stress is one of the major problems limiting crop production and eco-environmental quality in greenhouse soil. The objective of this study was to evaluate the effectiveness of organic residues (Chinese milk vetch, maize stalk, rice straw, and rye straw) for reducing salt activity in greenhouse soil. Organic residues was incorporated with salt-accumulated soil (EC, 3.0 dS $m^{-1}$) at the rate of 5% (wt $wt^{-1}$) and the changes of electrical conductivity (EC) was determined weekly for 8 weeks under incubation condition at $30^{\circ}C$. The EC, microbial biomass carbon (MBC), and water soluble ions in soil was strongly affected by C/N ratio of organic residues. After 8 weeks incubation, the concentration of water soluble $NO_3{^-},\;Ca^{2+}$, and $Mg^{2+}$ was significantly decreased in organic residues having high C/N ratio (maize stalk, rice straw, and rye straw) incorporated soil compared to organic residues having lower C/N ratio (Chinese milk vetch) incorporated soil. The EC value in Chinese milk vetch incorporated soil was higher than control treatment. In contrast, maize stalk, rice straw, and rye straw amended soil was highly decreased the EC value compared to control and Chinese milk vetch applied soil after 4 weeks incubation. Our results indicated that incorporation of organic residues having high C/N ratio (>30) could reduce salt activity resulting from reducing concentration of water soluble ions.

미국산과 인도산 옥수수의 steam flaking 처리가 공정라인별 mycotoxin 함량의 변화와 in vitro 발효 특성에 미치는 영향 (Effects of Steam Flaking of Corns imported from USA and India on the in vitro Fermentation Characteristic and the Mycotixin Contents of Logistic Processing Line)

  • 이신자;이지훈;신년학;한정훈;현종환;문여황;이성실
    • 생명과학회지
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    • 제19권1호
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    • pp.65-74
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    • 2009
  • 본 연구는 미국산 옥수수와 인도산 옥수수의 steam flaking 처리가 in vtro 가스발생량과 미생물 성장량 그리고 곰팡이 독소 aflatoxin $B_1$과 ochratoxin A의 농도에 미치는 영향을 구명하기 위하여 수행되었다. 실험 설계는 4개의 처리구, (1) USCW (미국산 무처리 옥수수), (2) USCF (미국산 steam flaking 옥수수 ), (3) IDCW (인도산 무처리 옥수수) 그리고 (4) IDCF (인도산 steam flaking 옥수수), 처리구당 4반복으로 6개의 발효시간대(3, 6, 9, 12, 18 및 24)를 두고 in vitro 실험을 수행하였다. 공시한 옥수수중 aflatoxin $B_1$이나 ochratoxin A와 같은 곰팡이 독소의 함량은 항구, hopper, 사일로 그리고 가공 전까지 보관기간이 길어짐에 따라 증가하는 경향을 보였다. 공정라인별로 곰팡이 독소를 측정한 결과 입고 시 인도산 옥수수(IDCW)와 미국산 옥수수 (USCW)의 aflatoxin $B_1$ 수치는 각각 11.71 ppb와 1.78 ppb으로 나타났지만 steam flaking 후의 aflatoxin $B_1$ 함량은 USCW 구와 IDCW구에서 전혀 검출되지 않아(0.00 ppb) steam flaking 처리가 곰팡이 Aspergillus flavus를 감소시킬 수 있는 것으로 조사되었다. 그러나 이러한 경향은 ochratoxin A 함량에서 관찰되지 않았다. In vitro 실험에서 gas 발생량은 원산지별로는 미국산 옥수수 (USCW & USCF)가 인도산 옥수수 (IDCW & IDCF) 보다 유의적으로 높았으며 가공 처리별로는 steam flaking 처리한 옥수수가 알곡 옥수수보다 발효 3시간대를 기준으로 $1.5{\sim}2%$ 정도 높았다. 배양액 중의 pH 는 $6.05{\sim}6.54$의 범위로서 미생물이 성장하기에 적정한 pH를 유지하였으며 처리 구간에 유의적인 차이는 찾아 볼 수 없었으나 USCF구의 pH가 다른구에 비해 다소 낮았다. pH는 배양 12 시간까지 감소하였으며 이 시간 중에 가스 발생량은 급격히 증가하였다. In vitro 미생물 성장량도 발효 18시간까지 증가하다가 그 이후 시간대에서는 성장량이 증체를 보이거나 오히려 감소하는 경향이었다. 결론적으로 원산지별로는 in vitro 실험결과와 곰팡이 독소 함량을 기준으로, 미국산 옥수수가 인도산 옥수수보다는 품질이 훨씬 높았으며, 수입산 옥수수의 steam flaking 처리는 invitro 가스발생량 및 미생물 성장량을 개선 시킬 뿐만 아니라, aflatoxin $B_1$이나 ochratoxin A와 같은 곰팡이 독소를 감소시키는 역할을 하였다.