• Title/Summary/Keyword: Incompatibility

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Cytotoxicity of Ultra-pure TiO2 and ZnO Nanoparticles Generated by Laser Ablation

  • Jeong, Minju;Park, Jeong Min;Lee, Eun Jeong;Cho, Yea Seul;Lee, Chunghyun;Kim, Jeong Moo;Hah, Sang Soo
    • Bulletin of the Korean Chemical Society
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    • v.34 no.11
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    • pp.3301-3306
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    • 2013
  • This paper aims to address the cellular toxicity of ultra-pure titanium dioxide ($TiO_2$) and zinc oxide (ZnO) nanoparticles (NPs) frequently employed in sunscreens as inorganic physical sun blockers to provide protection against adverse effects of ultraviolet (UV) radiation including UVB (290-320 nm) and UVA (320-400 nm). In consideration that the production and the use of inorganic NPs have aroused many concerns and controversies regarding their safety and toxicity and that microsized $TiO_2$ and ZnO have been increasingly replaced by $TiO_2$ and ZnO NPs (< 100 nm), it is very important to directly investigate a main problem related to the intrinsic/inherent toxicity of these NPs and/or their incompatibility with biological objects. In the present study, we took advantage of the laser-assisted method called laser ablation for generation of $TiO_2$ and ZnO NPs. NPs were prepared through a physical process of irradiating solid targets in liquid phase, enabling verification of the toxicity of ultra-pure NPs with nascent surfaces free from any contamination. Our results show that $TiO_2$ NPs are essentially non-poisonous and ZnO NPs are more toxic than $TiO_2$ NPs based on the cell viability assays.

A study on the amorphous s-i-n photodiode integrated with CMO IC (CMOS IC와 집적 가능한 비정질 p-i-n 광 수신기 제작에 관한 연구)

  • Kwak, Chol-Ho;Yoo, Hoi-Jun;Jang, Jin;Moon, Byoung-Yeon
    • Korean Journal of Optics and Photonics
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    • v.8 no.6
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    • pp.500-505
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    • 1997
  • Experimental amorphous photodiode is fabricated on CMOS IC using a-Si:H p-i-n structure. Amorphous photodiode is scuccessfully integrated on CMOS IC using amorphous Si produced by PECVD system. The PECVD system can deposit a-Si:H at low temperature so that photodiode can be integrated with CMOS IC structure without any process incompatibility. The fabricated amorphous photodiode has a breakdown voltage of below -20 V, a leakage current of about 1 $\mu\textrm{A}$, and turn-on voltage of 0.6~0.8 V. It is demonstrated that the photocurrent of optical signal can be turned on and off by a small voltage and the fabricated amorphous p-i-n photodiode can be used as an optical switch.

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Studies on the biochemical characteristics and plasmid profiles of Salmonella typhimurium isolated from pigeons and aquatic birds (비둘기 및 수생조류(水生鳥類) 유래(由來) Salmonella typhimurium의 생물화학적(生物化學的) 특성(特性)과 plasmid profile에 관(關)한 연구(硏究))

  • Park, No-chan;Choi, Won-pil
    • Korean Journal of Veterinary Research
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    • v.30 no.2
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    • pp.203-214
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    • 1990
  • A total of 166 strains of Salmonella (S) typhimurium var copenhagen isolated from pigeons (164 strains) and aquatic birds (2 strains) were examined for the biochemical characteristics and plasmid profiles. All the strains were sensitive to ampicillin, chloramphenicol, gentamicin, kanamycin and sulfadimethoxine. But 13 strains(7.8%) were resistant to streptomycin (Sm), 2 (1.2%) to tetracycline, 2 (1.2%) to rifampicin, and 1 (0.6%) to nalidixic acid. Among drug resistant strains, only one strain resistant to Sm contained conjugative R plasmid which was fertility inhibition and incompatibility group $I_{\alpha}$. All the strains were sensitive to cobalt chloride, cupric sulfate, lead nitrate, mercuric chloride and silver nitrate. Of 166 isolates, 6 (3.6%) were resistant to sodium arsenate and 1 (0.6%) to potassium tellurite. Among 166 isolates, 1 (0.6%) was colicinogenic, 12 (7.2%) sucrose fermenters, and 166 (100%) maltose fermenters. Plasmid profiles were confirmed as being 4 or 5 plasmids, and their molecular weight ranged 3.2 to 60 megadalton (MD). All the strains harbored 60 Md plasmid. There are three patterns by the plasmid profile, 150 isolates (90.4%) were pattern I (3.2, 3.5, 33, 60Md), 14 (8.4%) pattern II (3.2, 3.5, 29, 60Md), and 2 (1.2%) pattern III (4.2, 7.8, 8.5, 15, 60Md). S typhimurium var copenhagen strains containing 60Md plasmid were resistant to killing by 90% normal guinea pig serum.

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A Case Study of Active Workflow Component Architecture on Constraints Based (제약식 기반의 능동적 워크플로우 컴포넌트 아키텍쳐 사례 연구)

  • Seo, Jang-Hoon;Shim, Sang-Yong;Lee, Kun-Hyuk;Park, Myeong-Kyu
    • Proceedings of the Safety Management and Science Conference
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    • 2006.11a
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    • pp.415-426
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    • 2006
  • Many technical and nontechnical issues hinder enterprise wide workflow management. The most significant technical issue is the inability to deal with the heterogeneity among users, workflow types, and WFMSs. Not all users demand the same workflow functionality, so user interfaces of different levels of sophistication are required. Because workflow types cannot always be fully predefined, they often need to be adjusted or extended during execution. Unlike relational database management systems, however, each WFMS often has differing workflow metamodels. This leads to incompatibility between WFMSs, making integration into an environment comprising many heterogeneous WFMSs a troublesome and sometimes impossible task. Current Workflow system consists mainly of Database system. It contains some problems like that the integration relationship among system processes cant be expressed properly. This research has been focused on two phases that should be considered in the Workflow system. First of all, the first phase is the analysis phase; one of its role is to figure out independent execution task unit(Workflow component). The second phase is design phase that provides with the framework to execute these task units actively. The Workflow component extraction method in the analysis phase uses a analysis method called C-C Net and, in the design phase, the architecture that makes the these Workflow component executed actively is provided. Through this research, each process is divided into a task unit and more effective Workflow system could be formed by executing these units actively. Current system layer calls task units, on the other hand, the Workflow system this research implemented provides with the architecture that places a layer between them that controls task units actively.

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A General-Purpose Service Information Processing System for Integrated Data Broadcasting Environment (통합 데이터 방송 환경을 위한 범용 서비스 인포메이션 처리 시스템)

  • Jeon, Je-Min;Choi, Hyeon-Seok;Kim, Jung-Sun
    • The KIPS Transactions:PartC
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    • v.16C no.1
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    • pp.101-108
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    • 2009
  • The data broadcasting service, which is growing remarkably today, provides viewers with useful information as well as high quality video and audio. Service information is a kind of additional data that contains a wide range of information such as channel list and/or program title. Each service information is transmitted in the form of a table. And most standard committees have specified their own table list used for carrying the service information. Consequently, It causes incompatibility among services that each broadcast operators produce because the tables that they use differ from each other. In this paper, we propose a general-purpose service information processing system for an integrated data broadcasting middleware that is compatible with heterogenous broadcasting environments. The system is able to change its target table list dynamically without any code modification. Futhermore, we also adopted a thread pool model for efficient parsing and event dispatching.

A Development of GVP for Hierarchical POI Information Visualization based on GML (GML 기반 계층적 POI 정보 가시화를 위한 GVP 개발)

  • Song, Eun-Ha;Park, Yong-Jin;Jeong, Young-Sik
    • The KIPS Transactions:PartD
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    • v.15D no.4
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    • pp.541-548
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    • 2008
  • Today, GIS service requires not only a simple map visualization but also geographical information of each object. However, POI service provides simply geographical naming service only because of lacking in geographical information of objects. In addition, geographical space data representation functioning that is the basis for most GIS has not been standardized yet. In this paper, it is designed that POI DB that is hierarchical and user-oriented and it is constructed that GVP(GML Viewer POI) that is the basis of GML specification to overcome difference and incompatibility of map visualization. GVP adds POI DB in a 3-Layer structure to dBase file managing the information of SHP file attributes. Therefore, POI visualization enables hierarchical search, by providing POI information in directory-type grouping. Consisting of map visualization and POI visualization, GVP regenerates attributes in the form of individual objects and responds to user events immediately.

Analysis of Non-segregated S-allele Strain by Single-Locus Hypothesis in Self-incompatible Brassica campestris (자가불화합성 Brassica campestris에 있어서 단일유전자좌가설에 의해 분리되지 않는 S-유전자 계통의 분석)

  • 노일섭
    • Journal of Plant Biology
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    • v.36 no.2
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    • pp.127-132
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    • 1993
  • Self-incompatibility in Brassica campestris is controlled by multi-allele system in a single genetic locus, the S locus, and it is elucidated that S-glycoproteins are S gene products. In this experiments, we examined the genetic mode(pollen tube behavior and segregation of S-glycoprotein), characteristic of S-glycoproteins and DNA constitution within nuclear genome on S gene family that unexplained by single locus model, and investigated the segregation pattern of S-glycoproteins in bred F1 generation. By diallel cross among the 15 plants within one family the existence of three types of homozygotes and three types of heterozygotes were observed, and segregation of S-allele could not explained by single locus model. From the results of IEF-immunoblot analysis for non-segregated individual plant, the segregation pattern of S specific bands was corresponded with results of diallel cross except with one case(SaSa genotype). The molecular weight of 6 different S-genotype varied in near by 50 kD, and each genotype expressed with 2 or 3 bands. Specific bands in SaSa, SbSb, ScSc has almost similar molecular weight between them. Southern analysis of genomic DNA probed with S-glycoprotein cDNA for 6 different genotypes revealed that there are clear difference in polymorphism, multiple bands of hybridization, when restriction enzymes of EcoR I were used. It could be assumed that there are several sequences related to the S-glycoprotein structural genes within their nuclear genome. Therefore, we suggested the possibilities that S-allele system could be controlled by multi-locus, that dominance-recessive interactions could be explained by modifier gene or supressor gene based on the results of abnormal segregation of S-glycoprotein in bred F1. The F2 analyses are progressing in now.

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Maternal killer-cell immunoglobulin-like receptors and paternal human leukocyte antigen ligands in recurrent pregnancy loss cases in Turkey

  • Elbasi, Mehmet Onur;Tulunay, Aysin;Karagozoglu, Hale;Kahraman, Semra;Eksioglu-Demiralp, Emel
    • Clinical and Experimental Reproductive Medicine
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    • v.47 no.2
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    • pp.122-129
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    • 2020
  • Objective: The survival of a semi-allogeneic fetus depends on several immunological mechanisms, and it has been suggested that recurrent pregnancy loss (RPL) could develop as a result of one or more immunological abnormalities. Methods: Compatibility between partners for human leukocyte antigen (HLA) genotypes and the relationships between maternal killer-cell immunoglobulin-like receptor (KIR) and paternal HLA-Bw4/Bw6 and HLA-C1/C2 supra-groups were investigated in 25 couples with RPL in comparison to healthy couples with children. HLA and KIR genotyping was performed using polymerase chain reaction with sequence-specific primers and/or sequence-specific oligonucleotides. Results: HLA class I incompatibility between partners, especially in HLA-B alleles, was more common in the RPL group (p= 0.01). HLA-C2 homozygosity was more frequent in the male partners of RPL couples than in other groups (p= 0.03). The KIR2DL5 gene frequency was significantly higher in both the female and male partners of RPL couples, whereas the KIR2DS3 gene frequency in male partners of RPL couples was significantly reduced (p= 0.03). The presence of KIR2DL3 in women with RPL was correlated with the presence of HLA-C2 alleles in their spouses (p= 0.03). Conclusion: Our data from a Turkish population suggest that male HLA-C2 homozygosity may play an important role in RPL. Additionally, an incidental match between male HLA-C2 and female HLA-C1 ligand KIR receptors might perturb the balance between activatory and inhibitory KIR-ligand interactions during pregnancy in couples affected by RPL. The roles of orphan KIR2DL5 and orphan KIR2DS3 in RPL remain obscure.

Applying Aqueous Two Phase Systems to Multi-layer Cosmetics (다중 층 화장료에서 수성 이상계의 응용)

  • Hong, Junki;You, Jaewon;Yoo, Jangyung;Nam, Seungok;Lee, Sanggil;Pyo, Hyeongbae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.39 no.2
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    • pp.83-88
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    • 2013
  • The aqueous two phase system has biocompatibility, because it is physically separated into an immiscible liquid multi-layer induced by incompatibility among hydrophilic components dissolved in the water phase. we have applied this principle to aqueous multi-layer liquid cosmetics and select two representative systems. What it was experimentally obtained was the phase diagrams including a binodal curve, a critical point, tie lines of concentration and tie curves of phase separating volume ratio and phase separating time. From the phase diagrams, we were able to observe existence of the optimum condition to prepare the aqueous multi-layer cosmetics for the systems.

Loss of a Strain-Specific Protein by Bacterial Infection in Amoeba proteus (Amoeba proteus에 있어서 박테리아 감염에 의한 변이주 특이성 단백질의 손실)

  • Ahn, Tae-In;Park, Eui-Yul
    • The Korean Journal of Zoology
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    • v.28 no.1
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    • pp.21-30
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    • 1985
  • By two-dimensional gel electrophoresis loss of a cell-specific protein was detected in tD strain of Amoeba proteus that had been infected by symbiotic bacteria extracted from xD strain. In 50 days of experimental infection by induced phagocytosis the host amoeba lost the ability to synthesize the tD cell-specific protein even after removal of the infective bacteria and xD cell-specific protein by growing the amoebae at $27^\\circC$. By this time the host amoebae were obligately dependent on the bacteria. From these and other results (Lorch and Jeon, Science 221:549), it is clear that the incompatibility of the infected nuclei with the cytoplasm of the uninfected amoeba and the obligate dependence of the host on bacteria are due to the irreversible inactivation or the loss of the cell-specific gene by bacterial infection in this amoeba.

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