• KSBB Journal
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• v.19 no.4
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• pp.321-326
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• 2004

Microparticles of an inclusion complex between itraconazole and 2-hydroxypropyl-${\beta}$-cyclodextrin (HP-${\beta}$-CD) were prepared using an environmentally-benign supercritical anti-solvent (SAS) process. In order to evaluate the degree of complexation, the thermal behavior of solid micro particulate complexes was investigated using differential scanning calorimetry. The experimental results obatined for the solubility and dissolution rate of the microparticulate inclusion complexes in a buffer solution of pH 1.2 showed that the complexation of itraconazole with HP-${\beta}$-CD results in a significant increase in the solubility and dissolution rate of itraconazole. For the microparticulate itraconazole/Hp-${\beta}$-CD inclusion complexes prepared by the SAS process, about 80% of itraconazole was found to dissolve in the buffer solution. Our experimental results confirmed that the SAS process is a promising method for the preparation of microparticles of water-insoluble drug/cyclodextrin inclusion complexes.

• Journal of Korean Academy of Nursing
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• v.14 no.2
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• pp.84-92
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• 1984

This article examined relationships between selected variables, such as demographic background, care, treatment variables, environmental characteristics, and patient's daily behavior and mood change. Relationship were determined between independent variabltherapeutic-rapeutie approach, demographic data, environmental management approach-,and dependent variable-patient's daily behavioral and mood change. 35 patients selected within some criteria in a psychiatric ward, were obserbed during 5 weeks by use of Wyatt's Behavior & Mood Rating Scale ac-cording to the object of the study. At the same time, the frequence of the care and treatment were collected. Criteria for sample selection and independent variables as an influential factor to the patient behavioral change, based on a literature revienw and clinical experiences. Pearson's correlation and multiple regression analysis were used to determine the influfntial factors to the patient behavioral change. Systematic reading (r=.8324), Psychiatrist's individual interview (r=.5764), tranquilizer (r=.3441) and hospitalization processing date (r=.4143) were related with patient's behavioral change. That is these 4 variables can be said to influence to the patient's behavior and mood. A stepwise multiple regression analysis of the effect of the independent varibles of systematic reading, psychintrists individual interview, tranquilizer and hospitalization processing date on the dependent variable, patient's behavioral change was carried out. Systematic reading with on R²of. 69 revealed to be the main influential factor to the patient's behavior and mood change, as the next factor psychiatrist individual interview. A total inclusion of these factors revealed a 73% prediction for the patient's behavior and mood change. But the most influential factor was the interaction of the systematic reading and psychiatrist's individual interview.

• Research in Community and Public Health Nursing
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• v.20 no.3
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• pp.351-360
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• 2009

Purpose: The purpose of this study was to develop a lecture on oral presentation and to evaluate changes in anger expression, assertive behavior, and self-esteem after lecture on oral presentation. Methods: The design was a nonequivalent control group pretest-posttest design. The participants were university students in nursing, of which 17 were assigned to the experimental group and 15 to the control group. The education was carried out for 2 hours, once a week for 14 weeks. Data was analyzed with SPSS/WIN 14 program, and included chi-square test, independent t-test, and repeated measure ANOVA. Results: Lecture on oral presentation showed significant differences in the changes of anger expression (F=10.122, p=.003) and assertive behavior (F=8.498, p=.007). Conclusion: Findings suggest that this lecture on oral presentation was effective in changing students' anger expression and assertive behavior. Therefore this lecture on oral presentation is recommended for inclusion in education for university students in nursing.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.26 no.4
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• pp.76-90
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• 2018

Despite the growing use of SNS and the increasing number of recruitment related to SNS, little research has been conducted between career preparation activities and relationship with SNS. Therefore, this study investigates the relationships among purpose of using instagram, flow of instagram and career preparation behavior using structural equation model, and by investigating the adjustment effect of the personal characteristic among them. To this end an online survey was conducted for students who want to be cabin crew. The results of this study show that motivation of using instagram had a positive and significant effect on flow of instagram, which in turn positively influenced career preparation behavior. Furthermore, it could be confirmed that there was a adjustment moderating effect on personal characteristic between purpose of using instagram and flow of using instagram. The results of this study suggest that the likelihood of recruitment for being cabin crew can be achieved by identifying mutual relationships among motivation of using instagram, flow of instagram, career preparation behavior, and personal characteristics.

• Bulletin of the Korean Mathematical Society
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• v.46 no.6
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• pp.1175-1188
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• 2009

In this paper, we study the behavior and sensitivity analysis of the solution set for a new system of parametric generalized nonlinear mixed quasi-variational inclusions with (A, ${\eta$)-accretive mappings in quniformly smooth Banach spaces. The present results improve and extend many known results in the literature.

• Communications of the Korean Mathematical Society
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• v.25 no.3
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• pp.427-441
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• 2010

In this paper, we study the behavior and sensitivity analysis of the solution set for a new system of generalized parametric multi-valued variational inclusions with (A, $\eta$)-accretive mappings in q-uniformly smooth Banach spaces. The present results improve and extend many known results in the literature.

• Korean Chemical Engineering Research
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• v.43 no.1
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• pp.110-117
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• 2005

In this work, solid-state inclusion complex powders of itraconazole and $2-hydroxypropyl-{\beta}-cyclodextrin(HP-{\beta}-CD)$ were produced by a supercritical anti-solvent (SAS) process. In order to evaluate the degree of complexation, the thermal behavior of the microparticulate complexes was investigated using differential scanning calorimetry. The experimental results obtained for the solubility and dissolution rate of the microparticulate inclusion complexes in a buffer solution of pH 1.2 showed that the complexation of itraconazole with $HP-{\beta}-CD$ results in a significant increase in the solubility and dissolution rate of itraconazole. The particle size of the SAS-produced inclusion complexes was dramatically reduced ($<0.1-0.5{\mu}m$) compared with untreated itraconazole ($30-50{\mu}m$) and $HP-{\beta}-CD$ ($50-100{\mu}m$). The solubility of itraconazole was increased with the increase of pressure at a constant temperature to ca. $758.6{\mu}g/mL$ in an aqueous medium of pH 1.2. The dissolution rate of itraconazole was observed to be significantly improved and about 90% of itraconazole was found to be dissolved within 5-10 min.

• Advances in concrete construction
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• v.1 no.3
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• pp.239-252
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• 2013

Mortar microstructure is considered as a three-phase composite material, which is cement paste, fine aggregate and interfacial transition zone. Interfacial transition zone is the weakest link between the cement paste and fine aggregate, so it has a significant role to determine the properties of cementitious composites. In this study, specimens (w/c = 0.35, 0.45, 0.55) with various volume fractions of fine aggregate ($V_f$ = 0, 0.1, 0.2, 0.3 and 0.4) were cast and tested. To predict the equivalent migration coefficient ($M_e$) and migration coefficient of interfacial transition zone ($M_{itz}$), double-inclusion method and Mori-Tanaka theory were used to estimate. There are two stages to estimate and calculate the thickness of interfacial transition zone (h) and migration coefficient of interfacial transition zone ($M_{itz}$). The first stage, the data of experimental chloride ion migration coefficient ($M_s$) was used to calculate the equivalent migration coefficient of fine aggregate with interfacial transition zone ($M_e$) by Mori-Tanaka theory. The second stage, the thickness of interfacial transition zone (h) and migration coefficient of interfacial transition zone ($M_{itz}$) was calculated by Hori and Nemat-Nasser's double inclusion model. Between the theoretical and experimental data a comparison was conducted to investigate the behavior of interfacial transition zone in mortar and the effect of interfacial transition zone on the chloride migration coefficient, the results indicated that the numerical simulations is derived to the $M_{itz}/M_m$ ratio is 2.11~8.28. Additionally, thickness of interfacial transition zone is predicted from $10{\mu}m$, 60 to $80{\mu}m$, 70 to $100{\mu}m$ and 90 to $130{\mu}m$ for SM30, M35, M45 and M55, respectively.

• Journal of the Korean Geosynthetics Society
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• v.9 no.4
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• pp.39-45
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• 2010

The effects of non-woven geotextiles on mechanical behavior of sand were investigated. A comprehensive series of triaxial compression tests were performed for these investigation on unreinforced and reinforced sand with geotextiles. The Joomunjin standard sand was used and non-woven geotextiles were included into sand specimen with three layers. The inclusion of non-woven geotextile reinforcement into sand increased the peak strength of sand significantly and the reinforced samples exhibited a greater axial strain at failure. Also the effect on number of reinforcement layers was studied and found as increasing the number of reinforcement layers resulting in more ductility by clogging developed in the shear band within the specimens. It was also found that the tendency of samples to dilate is restricted by non-woven geotextile inclusion. The effect of nunber of reinforcement layer increasing is just same to the effect of decreasing void ratio of sand in this case.

• Corrosion Science and Technology
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• v.14 no.3
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• pp.120-126
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• 2015

The usage of bending products recently have increased since many industries such as automobile, aerospace, shipbuilding, and chemical plants need the application of pipings. Bending process is one of the inevitable steps to fabricate the facilities. Induction heat bending is composed of compressive bending process by local heating and cooling. This work focused on the effect of induction heat bending process on the properties of ASME SA312 Gr. TP304 stainless steel pipes. Tests were performed for base metal and bended area including extrados, intrados, crown up, and down parts. Microstructure was analyzed using an optical microscope and SEM. In order to determine intergranular corrosion resistance, Double Loop Electrochemical Potentiokinetic Reactivation (DL-EPR) test and ASTM A262 practice A and C tests were done. Every specimen revealed non-metallic inclusion free under the criteria of 1.5i of the standard and the induction heat bending process did not affect the non-metallic inclusion in the alloys. Also, all the bended specimens had finer grain size than ASTM grain size number 5 corresponding to the grain sizes of the base metal and thus the grain size of the pipe bended by induction heat bending process is acceptable. Hardness of transition start, bend, and transition end areas of ASME SA312 TP304 stainless steel was a little higher than that of base metal. Intergranular corrosion behavior was determined by ASTM A262 practice A and C and DL-EPR test, and respectively step structure, corrosion rate under 0.3 mm/y, and Degree of Sensitization (DOS) of 0.001~0.075% were obtained. That is, the induction heat bending process didn't affect the intergranular corrosion behavior of ASME SA312 TP304 stainless steel.