• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제24권3호
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• pp.265-272
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• 2021

Purpose: Hypertrophic pyloric stenosis (HPS) is the most common cause of gastric obstruction in newborns. Extra-mucosal pyloromyotomy can be performed through a small laparotomy or laparoscopy. The aim of this study was to compare the two surgical techniques. We also analyzed the incidence of HPS in infants in the last 10 years in relation to the demographic trend of our province. Methods: We analyzed all the cases of HPS treated at our Unit between January 2010 and December 2019. The data were obtained from operating systems. Data about the demographic trends, in particular, the number of births and the population residing in the province of Verona from 2010 to 2019, were also retrieved. Results: During the study period, 60 patients were treated for HPS and met the inclusion criteria. Of these, 56 males and 4 females with an average age of 38±14 days at surgery were included. No differences were found in terms of the duration of surgery, post-operative complications, duration of hospitalization, and weight at the time of surgery. The only statistically significant data was the chlorine level in cases with and without post-operative vomiting (97±3.5 vs. 102±3.3 mmol/L, p<0.05). There was a lower incidence of HPS from 2014 to 2019; however, there was no significant evidence regarding the correlation between this and the reduced birth rate recorded in the province of Verona during the same period. Conclusion: Although laparoscopic pyloromyotomy is a highly complex procedure, it is a feasible alternative to the classic open technique.

• 대한통합의학회지
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• 제10권3호
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• pp.73-84
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• 2022

Background : Lymphedema is a progressive disorder characterized by the impairment of lymph flow from tissues to the blood circulation system. This occurs as a result of damage to the lymphatic system. Complex decongestive therapy (CDT) is a multimodal, conservative therapeutic approach that is used for the management of lymphedema. CDT consists of a combination of compression therapy, manual lymphatic drainage, exercise, and skin care. Purpose : This study aimed to provide a review of available physical therapy interventions as well as general care guidelines for patients with lymphedema. Methods : The recommendations and guidelines for physical therapy management, medical management, and general information were reviewed from the following sources: 1) The American Physical Therapy Association, 2) The Norton School of Lymphatic Therapy, and 3) The International Society of Lymphology. This review contains general information, including the medical management and the importance of physical therapy in lymphedema. Physical therapy management should be based on an assessment of the patients' presenting impairments, including based on inclusion or exclusion of physical therapy interventions. This review also outlines a step-by-step approach that starts with disease diagnosis and progression all the way through to rehabilitation as an outpatient. Conclusion : Depending on the patients' journey to recovery and the requirement for rehabilitation, physical therapy interventions should focus on the patients' needs including pain, appearance, physical function and general rehabilitation. We hope that this review will provide information on evidence-based physical therapy and general care to patients with lymphedema.

• Archives of Plastic Surgery
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• 제50권3호
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• pp.264-273
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• 2023

The medial sural artery perforator (MSAP) flap is a versatile fasciocutaneous flap, and yet is less commonly utilized than other free flaps in microvascular reconstructions of the head and neck. The aim is to conduct a high-quality Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA)- and Assessment of Multiple Systematic Reviews 2 (AMSTAR 2)-compliant systematic review comparing the use of the MSAP flap to other microvascular free flaps in the head and neck. Medline, Embase, and Web of Science databases were searched to identify all original comparative studies comparing patients undergoing head and neck reconstruction with an MSAP flap to the radial forearm free flap (RFFF) or anterolateral thigh (ALT) flap from inception to February 2021. Outcome studied were the recipient-site and donor-site morbidities as well as speech and swallow function. A total of 473 articles were identified from title and abstract review. Four studies met the inclusion criteria. Compared with the RFFF and the ALT flaps, the MSAP flap had more recipient-site complications (6.0 vs 10.4%) but less donor-site complications (20.2 vs 7.8%). The MSAP flap demonstrated better overall donor-site appearance and function than the RFFF and ALT flaps (p = 0.0006) but no statistical difference in speech and swallowing function following reconstruction (p = 0.28). Although higher quality studies reviewing the use of the MSAP flap to other free flaps are needed, the MSAP flap provides a viable and effective reconstructive option and should be strongly considered for reconstruction of head and neck defects.

• 대한중풍순환신경학회지
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• 제16권1호
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• pp.89-102
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• 2015

■ Objectives This study aimed to investigate the domestic research trend about Amyotrophic Lateral Sclerosis(ALS) treated with Traditional Korean Medicine(TKM). ■ Methods Searches of two major TKM databases were conducted for articles published up to July 2015. Searching keyword was "Lou Gehrig's disease" OR "amyotrophic lateral sclerosis". Studies dealt TKM for ALS were included. ■ Results 18 studies were met our inclusion criteria(two prospective studies, one retrospective study, one follow-up study, 14 case reports). Complex TKM intervention of herbal medication, acupuncture and pharmacopuncture was the most frequently used treatment. Individually, herbal medication was the most frequent followed by acupuncture. Short-term assessment showed improvement in ALS symptoms but long-term assessment showed progression of disease. Accessory symptoms including depression, anxiety and insomnia were improved in four studies. ■ Conclusion For more definite evidence, larger studies with long-term follow-up period are needed. Moreover, benefits that TKM can provide for ALS patients as a part of multi-disciplinary approach should be studied in depth.

• 한국중재학회지:중재연구
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• 제33권2호
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• pp.53-83
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• 2023

The investment agreement prepared at the beginning of inter-Korean economic cooperation in 2000 can be evaluated as very ineffective as a product of mutual political and diplomatic compromise rather than an effective protection for our investment assets. South Korean companies suffered a lot of losses due to the freezing of assets in the Geumgang mountain district and the closure of the Kaeseung Industrial Complex, but they did not receive practical damage relief due to institutional vulnerabilities. Currently, North Korea is under international economic sanctions of the UN Security Council, so it is true that the resumption of inter-Korean economic cooperation is far away, but North Korea's human resources and geographical location are still attractive investment destinations for us. Therefore, if strained relations between the two Koreas recover in the future and international economic sanctions on North Korea are eased, Korean companies' investment in North Korea will resume. However, the previous inter-Korean investment agreement system was a fictional systemthat was ineffective. Therefore, if these safety devices are not reorganized when economic cooperation resumes, unfair damage to Korean companies will be repeated again. The core of the improved investment guarantee system is not a bilateral system between the two Koreas, but the establishment of a multilateral system through North Korea's inclusion in the international economy. Specifically, it includes encouraging North Korea to join international agreements for the execution of arbitration decisions, securing subrogation rights through membership of international insurance groups such as MIGA, creating matching funds by international financial organizations. Through this new approach, it will be possible to improve the safety of Korean companies' investment in North Korea, and ultimately, it will be necessary to lay the foundation for mutual development through economic cooperation between the two Koreas.

• 정보처리학회 논문지
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• 제13권4호
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• pp.174-180
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• 2024

본 논문에서는 wav2vec 2.0과 KcELECTRA 모델을 활용하여 멀티모달 학습을 통한 감정 분류 방법을 탐색한다. 음성 데이터와 텍스트 데이터를 함께 활용하는 멀티모달 학습이 음성만을 활용하는 방법에 비해 감정 분류 성능을 유의미하게 향상시킬 수 있음이 알려져 있다. 본 연구는 자연어 처리 분야에서 우수한 성능을 보인 BERT 및 BERT 파생 모델들을 비교 분석하여 텍스트 데이터의 효과적인 특징 추출을 위한 최적의 모델을 선정하여 텍스트 처리 모델로 활용한다. 그 결과 KcELECTRA 모델이 감정 분류 작업에서 뛰어난 성능이 보임을 확인하였다. 또한, AI-Hub에 공개되어 있는 데이터 세트를 활용한 실험을 통해 텍스트 데이터를 함께 활용하면 음성 데이터만 사용할 때보다 더 적은 양의 데이터로도 더 우수한 성능을 달성할 수 있음을 발견하였다. 실험을 통해 KcELECTRA 모델을 활용한 경우가 정확도 96.57%로 가장 우수한 성능을 보였다. 이는 멀티모달 학습이 감정 분류와 같은 복잡한 자연어 처리 작업에서 의미 있는 성능 개선을 제공할 수 있음을 보여준다.

• 국제학술발표논문집
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• The 10th International Conference on Construction Engineering and Project Management
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• pp.722-729
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• 2024

The Nigerian Public Procurement Act (PPA, 2007) is still lagging in its vague definition of the requisite qualifications for procurement managers. Hitherto, tender evaluation committees have been constituted arbitrarily without any feed-forward structure. An advanced close-ended support system for constituting tender evaluation committees is hereby presented. A theoretical concept was followed by a design science methodology. A deterministic team-building model for tender evaluation committees is demonstrated. The optimisation algorithm relies on an additive analytical sequence and a complex factoring of anticipated group interaction. Match models, which proactively determine the effects of complementary participation of team players were adapted. It is an emerging technical solution for a relatively ignored research concern, which now makes a scientific team-building processin procurement possible through itinerant simulation. The deterministic strategy was validated by a hypothetical entity case while augmenting a few data entries. A restrictive decision space was created to enable the determination, identification and composition of tender evaluation team members' inclusion criteria in a committee. A questionnaire drawn from ten (10) procurement managers from Nigeria helped validate the soft team-building model. The support system is inflexible for accommodating probabilistic entries where target data is discontinuous. Minimising the discretionary assemblage of personnel to evaluate tenders is a potential benefit of adopting the support system. Public procuring entities can deploy the soft team-building support system with little adjustments to accommodate entity-specific peculiarities.

• Journal of Animal Science and Technology
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• 제45권4호
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• pp.569-576
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• 2003

본 연구는 영양소 수준을 낮춘 옥수수-대두박 기초 사료내 $\alpha$-galactosidase와 galactomannanase를 함유한 탄수화물 분해 복합효소제 (ENDO- POWER$^{\circledR}$)와 미생물 파이테이즈 (Natuphos$^{\circledR}$) 의 개별첨가 혹은 동시첨가가 육성돈의 생산성, 영양소 소화율 및 체중 증체 당 사료비에 어떠한 영향을 미치는 가를 평가하고자 실시 되었다. 개시 체중 29.1$\pm$0.14 kg의 육성돈 48두를 공시하여 28일간 사양시험을 실시하였다. 시험설계는 4처리를 두었으며, 처리당 3반복 반복당 4두의 육성돈이 완전임의 배치 되었다. 시험 처리는 1) CON (대조구), 2) LP+NTPS (대조구 사료에서 유효인 함량을 0.15% 단위 낮춘 사료에 미생물 파이테이즈 (Natuphos$^{\circledR}$) 0.1% 첨가 (500 FTU/kg 사료), 3) LEL+ENP (대조구 사료에서 대사에너지와 라이신 함량을 대조구 사료 대비 각각 3% 낮춘 사료에 탄수화물 복합효소제 (ENDP-POWER$^{\circledR}$) 첨가) 및 4) LPEL+ENZ (대조구 사료에서 대사에너지와 라이신 함량을 대조구 사료 대비 각각 3% 낮추고 유효인 함량을 0.15% 단위 낮춘 사료에 미생물 파이테이즈 0.1%와 탄수화물 복합효소제 0.1%를 각각 첨가)를 두었다. 전체 사양시험 기간동안 (28일), 일당 증체량 (ADG), 일당사료섭취량 (ADFI) 및 사료요구량 (Feed/gain)은 사료처리구에 따라 유의적인 차이를 나타내지 않았다(P>0.05). 그러나 저 영양소 수준 사료에 파이테이즈와 탄수화물 복합효소제의 개별적 혹은 동시 첨가는, 대조구에 비해, 시험 전기간에 걸쳐 사료효율을 다소 개선 시키는 경향을 보여주었다. 건물, 조단백질 및 칼슘 소화율에 있어서는 처리구간에 유의적인 차이를 보이지 않았으나, 총 에너지 소화율에 있어서는 LEL+ENP 처리구와 비교해 볼 때, LP+NTPS와 LPEL+ENZ 처리구가 유의적으로 높게 평가되었다 (p<0.05). 건물 배설량은 LPEL+ENZ 처리구가 가장 낮았으며, 칼슘과 인 배설량은 LP+NTPS구가 가장 낮았다(p<0.05). 사양시험 기간동안 소요된 전체 사료비용은 대조구와 비교하여 볼 때, 효소제 첨가 시 낮았으며, 특히 1 kg 증체 하는데 필요한 사료비용은 대조구와 비교하여 LP+NTPS, LEL+ENP, LPEL+ENZ가 각각 3.5% (609.1 vs. 588.3 원/kg), 13.8% (609.1 vs. 535.3원/kg), 12.4% (609.1 vs. 541.9 원/kg) 낮은 것으로 조사되었다. 결론적으로, 본 실험 결과는 옥수수-대두박 위주 육성돈 사료에 유효인, 에너지 및 라이신 함량을 낮추고 파이테이즈와 탄수화물 분해 복합 효소제를 첨가 시 육성돈의 성장에는 유해한 영향 없이 영양소 배설량을 감소 시킬 수 있으며, 또한 양돈 생산비를 감소 시킬 수 있는 가능성을 제시했다고 판단된다.

• 자원환경지질
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• 제22권4호
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• pp.303-314
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• 1989

경남거제지역 금(金)-은광상(銀鑛床)들은 후기 백악기 안산암류와 화강섬록암(83 m.y.)내의 열극을 충진한 함금(含金)-은(銀) 열수맥상(熱水脈狀) 광체로 구성된다. 열수광화작용(熱水鑛化作用)은 구조운동에 의하여 시기적으로 3회에 걸쳐 진행되었다. 초기 제$370^{\circ}C$의 고온에서 후기 $200^{\circ}C$에 이르는 제 I, II 광화기(鑛化期)에서는 각기 상이한 열수계(熱水系)에 의하여 석영, 유화물이 침전하였으며, $320^{\circ}C$를 전후로 하여 광화류체(鑛化流體)의 비담(沸膽)현상이 일어났다. 제 I, II 광화작용(鑛化作用)시의 압력은 <100기압이고, 심도는 500~1,250m였다. 금(金)-은(銀)의 주광화시기(主鑛化時期)인 광화(鑛化) I 기(期)의 공생광물에 대한 유체포유물(流體包有物) 및 광물열수학적(鑛物熱水學的) 연구에 의하면, 황철석, 섬아연석, 황동석은 $290^{\circ}C$ 이상의 고온에서 비담작용(沸膽作用)과 동시에 정출하였고, 사면동석, 에렉트렘, 스튜자이트는 금(金)-유황종(硫黃種)의 농도가 $10^{-3}{\sim}10^{-4}$molal, 상당염농도(相當鹽濃度)가 2~6wt.% NaCl인 광화유체(鑛化流體)로부터 $220{\sim}260^{\circ}C$, 유황 및 산소분압이 각각 $10^{-11.8}{\sim}10^{-14}$, $10^{-35}{\sim}10^{-36}$ atm인 물리 화학적 환경하에서 침전하였다. 균질화(均質化) 온도와 염농도(相當鹽濃度)와의 관계는 천수류입(天水流入)에 의한 광화류체(鑛化流體)의 냉각(冷却) 및 희석(稀釋)작용이 광석광물 침전의 주된 메키니즘이었음을 지시해 주며, 유체내(流體內) 환원(還元) 유황종(硫黃種)($H_2S$)의 감소에 따른 금류화복합체(金硫化複合體)($Au(HS)_2$) 의 파괴로 금(金)의 침전이 유도되었으리라 사료된다. 유황 및 탄소, 산소 안정동위원소(安定同位元素) 연구(硏究)결과, 광화류체내(鑛化流體內)의 유황 및 탄소는 심부화성(深部火成)기원이었고, 방해석의 산소 안정동위원소(安定同位元素)값으로부터 열수계(熱水系)에서 천수(天水)가 지배적인 역할을 하였으리라 사료된다.

• KSBB Journal
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• 제22권5호
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• pp.328-335
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• 2007

본 연구에서는 뛰어난 주름개선효능을 가지고 있지만 수용액상에서의 낮은 용해도로 인해 사용에 제약이 있는 UA의 용해도를 향상시키기 위하여 HP-$\beta$-CD와의 포접체를 형성하는 UA함유 제제를 제조하고자 하였으며 특히 초임계유체 공정기술을 포접화합물 제조에 도입하여 초임계 기술의 적용의 가능성을 조사하였다. UA의 용해도를 증가시키기 위한 제조방법으로 HP-$\beta$-CD와의 혼합물을 반죽법, 용매증발법 및 초임계유체공정을 이용하여 제조하고, 각 제조시료들의 용해도 증가 및 특성을 확인한 결과 용매증발법과 초임계 ASES공정에 의해 물에 대한 용해도가 증가된 UA/HP-$\beta$-CD 제제를 얻을 수 있었다. 각 방법에 의해 제조된 UA 함유 제제의 화장품 제형에서의 안정도 실험을 수행하였으며 실험결과 유화제형에서는 모든 제제가 시간 및 온도에 대한 안정성을 보였으나 가용화제형에서는 ASES 제제와 Ursolisome 제제의 경우 시간이 경과하거나 함유 UA농도가 증가함에 따라 화장품 제형의 현탁도가 증가함을 확인할 수 있었다.