• Title/Summary/Keyword: IncP

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A comparative analysis of canine pancreatic lipase tests for diagnosing pancreatitis in dogs

  • Jin-Kyung Kim;Sun Young Hwang;Se Eun Kim;Gahyun Lee;Soungjin Ji;Jungho Kim;Yongbaek Kim
    • Journal of Veterinary Science
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    • v.25 no.3
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    • pp.48.1-48.12
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    • 2024
  • Importance: Early diagnosis of canine pancreatitis is challenging due to non-specific clinical signs. Currently, abdominal ultrasonography and measurement of canine pancreatic lipase (cPL) have been employed for the diagnosis of pancreatitis. Objective: Many qualitative and quantitative commercial cPL tests have been developed and used in veterinary clinics. This study aimed to compare three different methodologies SNAP cPL, Spec cPL, and Vcheck cPL tests to assess the concordance of these assays. Methods: Fifty serum samples were collected from 36 dogs with or without pancreatitis and subjected to SNAP cPL, Spec cPL, and Vcheck cPL tests. Agreement and correlation coefficients were calculated between the test results, and correlations were determined during the management of the patients. Results: The results of the three cPL assays were strongly correlated in 47/50 serum samples (94%). Cohen's kappa analysis between the Spec cPL and Vcheck cPL showed near perfect agreement (κ = 0.960, p < 0.001), SNAP cPL and Vcheck cPL (κ = 0.920, p < 0.001), and Spec cPL and SNAP cPL (κ = 0.880, p < 0.001). The correlation coefficients (r) between data from Spec cPL and Vcheck cPL tests was calculated by Spearman's correlation test (r = 0.958, p < 0.001). Furthermore, the patterns of change in serum cPL concentrations determined using Spec cPL and Vcheck cPL were significantly consistent during the monitoring period in 11 patients. Conclusions and Relevance: Our data illustrated that Spec cPL and Vcheck cPL tests are compatible for clinical use in the diagnosis and monitoring of canine pancreatitis.

Study on Education Content Delivery System in Hybrid P2P based Computing Environment (혼합형 P2P 기반 컴퓨팅환경에서의 교육 컨텐츠 전송 시스템에 대한 연구)

  • Kim, Jin-Il
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • v.9 no.2
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    • pp.658-661
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    • 2005
  • Internet-based client/server architecture of Contents Delivery System suffers from frequent disconnections and security treats caused by dependency of the server or overload. But, We reached the limit to the increase of the server because a contents quality enhance and Internet user explosively increase. Therefore, a P2P based computing methods are used for sloving these issues. In this paper, We implement and design the Education Content Delivery System for cyber education system using idle Computing Power in P2P computing to share computing resources. We implement not only Internet infrastructure but also satellite infrastructure system, and designed to transfer real-time or non real-time contents.

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Modulation of Kex2p Cleavage Site for In Vitro Processing of Recombinant Proteins Produced by Saccharomyces cerevisiae

  • Mi-Jin Kim;Se-Lin Park;Seung Hwa Kim;Hyun-Joo Park;Bong Hyun Sung;Jung-Hoon Sohn;Jung-Hoon Bae
    • Journal of Microbiology and Biotechnology
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    • v.33 no.11
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    • pp.1513-1520
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    • 2023
  • Kex2 protease (Kex2p) is a membrane-bound serine protease responsible for the proteolytic maturation of various secretory proteins by cleaving after dibasic residues in the late Golgi network. In this study, we present an application of Kex2p as an alternative endoprotease for the in vitro processing of recombinant fusion proteins produced by the yeast Saccharomyces cerevisiae. The proteins were expressed with a fusion partner connected by a Kex2p cleavage sequence for enhanced expression and easy purification. To avoid in vivo processing of fusion proteins by Kex2p during secretion and to guarantee efficient removal of the fusion partners by in vitro Kex2p processing, P1', P2', P4, and P3 sites of Kex2p cleavage sites were elaborately manipulated. The general use of Kex2p in recombinant protein production was confirmed using several recombinant proteins.

Optimization of orthodontic microimplant thread design (교정용 마이크로 임플란트의 나사산 디자인 최적화)

  • Kim, Kwang-Duk;Yu, Won-Jae;Park, Hyo-Sang;Kyung, Hee-Moon;Kwon, Oh-Won
    • The korean journal of orthodontics
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    • v.41 no.1
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    • pp.25-35
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    • 2011
  • Objective: The purpose of this study was to optimize the thread pattern of orthodontic microimplants. Methods: In search of an optimal thread for orthodontic microimplants, an objective function stability quotient (SQ) was built and solved which will help increase the stability and torsional strength of microimplants while reducing the bone damage during insertion. Selecting the AbsoAnchor SH1312-7 microimplant (Dentos Inc., Daegu, Korea) as a control, and using the thread height (h) and pitch (p) as design parameters, new thread designs with optimal combination of hand p combination were developed. Design soundness of the new threads were examined through insertion strain analyses using 3D finite element simulation, torque test, and clinical test. Results: Solving the function SQ, four new models with optimized thread designs were developed (h200p6, h225p7, h250p8, and h275p8). Finite element analysis has shown that these new designs may cause less bone damage during insertion. The torsional strength of two models h200p6 and h225p7 were significantly higher than the control. On the other hand, clinical test of models h200p6 and h250p8 had similar success rates when compared to the control. Conclusion: Overall, the new thread designs exhibited better performance than the control which indicated that the optimization methodology may be a useful tool when designing orthodontic microimplant threads.

Effect of Dyeing Conditions on Dyeing Characteristics in Silk during Natural Dyeing Using the Raw Juice of Indigo Plants (쪽 생즙액을 이용한 천연염색에서 염색조건이 견직물의 염색특성에 미치는 영향)

  • Yun Jae-Gil;Jang Hong-Gi;Heo Buk-Gu;Park Yun-Jum
    • Korean Journal of Plant Resources
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    • v.18 no.3
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    • pp.417-423
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    • 2005
  • In order to investigate effects of dyeing conditions on the dyeing characteristics in silk during natural dyeing using indigo plants , various dyeing conditions including the temperature of dyeing solution, dyeing period, the concentration and pH of dyeing solution and mordants were treated. As the temperature of dyeing solution decreases low, the color of silk surface showed lower b value. The color of silk surface showed G line when the dyeing solution was $-5^{\circ}C$ and room temperature and GY line at more than $40^{\circ}C$. Coloring degree increased high as the temperature increases. Dyeing period showed no effect on the surface color, but as dyeing period was longer the coloring degree increased. When the concentration of dyeing solution was $1\~4\%$, the silk was colored to BG line and $5\%$ to B line. The coloring degree increased as the concentration of dyeing solution more increased. The pH of dyeing solution sensitively affected coloring of silk. The pH lower than 7 showed G line, pH 8 showed GY line and pH 9 showed YR line. Coloring degree decreased as pH was more increases. Surface color of silk was different according to the kinds of natural mordants and coloring degree was increased by the natural mordants.

Steady-state Operational Strategies of UPFC in the KEPCO Transmission System

  • Chang, B.H.;Choo, J.B.;Xu, X.K.;Lam, B.P.
    • KIEE International Transactions on Power Engineering
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    • v.3A no.3
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    • pp.161-167
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    • 2003
  • This paper presents a study performed to investigate the steady-state operational strategies of UPFCs in the Jeollanam-Do system in Korea. The objective of the study was to determine the UPFC operating points under normal and contingency conditions. The study consists of developing load flow models to simulate different load levels with and without UPFCs in the system, assessing the effectiveness of UPFCs by contingency analysis, and introducing optimal corrective actions for removing voltage problems caused by contingencies. The paper describes analytical tools, models and approach. It also includes analysis and discussion of the study results. The paper contributes to the area of transmission operational studies with FACTS applications.

Effect of Biochar bead on Adsorption of Heavy Metals

  • Kim, Ho-Jin;Lee, Hochul;Kim, Hyuck-Soo;Kim, Kye-Hoon
    • Korean Journal of Soil Science and Fertilizer
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    • v.47 no.5
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    • pp.351-355
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    • 2014
  • In recent years, biochar has received much attention as soil amendment, enhancing soil fertility and reducing toxicity of heavy metals with its large specific surface area and high pH. Biochar has also the effect of alleviating global warming by carbon sequestration from recycling organic wastes by pyrolysis. However, scattering of fine particles of biochar is a hindrance to expand its use from human health point-of-view. Alginate, a natural polymer without toxicity, has been used for capsulation and hydrogel fabrication due to its cross-linking nature with calcium ion. In this study, the method of cross-linkage between alginate and calcium ion was employed for making dust-free biochar bead. Then an equilibrium adsorption experiment was performed for verifying the adsorption effect of biochar bead on heavy metals (cadmium, copper, lead, arsenic, and zinc). Results showed that biochar bead had effects on adsorbing heavy metals, especially lead, except arsenic.

Study of Speed Control DC Motor Based SOC (SoC 기반 DC Motor의 속도제어 연구)

  • Park, In-Soo;Kim, Jung-Ok;Park, Kwang-Hyeon;Mustafa, Khalifa Eltayeb Kh
    • Proceedings of the KIEE Conference
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    • 2009.07a
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    • pp.1960_1961
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    • 2009
  • 본 논문에서는 PID, PWM, HSC, 컴퓨터와의 호스트 통신, 외부 DAC 인터페이스를 FPGA만을 이용하여 하나의 Chip에 구현하고 DC 서보 모터의 속도를 설정한 제어 상태로 안정화시킬 수 있는 시스템을 구현하고자 한다. 컴퓨터에서 설정한 설정치(SV)와 P, I, D의 이득 값을 호스트 통신으로 데이터 블록은 해당 블록으로 전달하며 DC 서보 모터의 엔코더에서 나오는 $90^{\circ}$ 위상차가 있는 2채널의 펄스는 HSC 블록을 거쳐 프로세스치(PV)를 생성 고 이로부터 얻어진 SV와 PV의 편차(E)를 산출한 후 PID 제어 동작을 수행한다. 그 결과인 조작치(MV)를 PWM 블록에 제공하여 실질적으로 DC 서보 모터를 구동하는 H-bridge 회로를 구동한다. 또한 FPGA 내부의 SV, PV, E, MV를 오실로스코프로 계측하기 위해 DAC 인터페이스 블록을 첨가 하여 외부 디지털 아날로그 변환기(DAC)를 제어 하였다.

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A Study of MPPT Algorithm for Low Insolation (저일사강도에서 MPPT를 동작시키기 위한 알고리즘 연구)

  • Yu, Gwon-Jung;Jeong, Yeong-Seok;Kim, Gi-Hyeon;Choe, Ju-Yeop
    • The Transactions of the Korean Institute of Electrical Engineers B
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    • v.51 no.3
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    • pp.142-149
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    • 2002
  • As is well-known, the maximum power point (MPP) of PV power generation system depends on array temperature and solar insolation, it is necessary to track MPP of solar array all the time. Among various MPP control algorithms, the constant voltage control method, the perturbation and observation (P&O) method and the incremental conductance method (IncCond) have drawn many attractions due to the usefulness of each system. In this parer, the effectiveness of above mentioned three different control algorithms are thoroughly investigated via simulations and preposed efficiency evaluation method on experiment. Both the steady-state and transient characteristics of each control algorithms along with measured efficiency are analyzed, respectively. Finally, a novel MPPT control algorithm combining the constant voltage control and IncCond method for low insolation condition is proposed to improve efficiency of the 3KW PV power generation system.