• 제목/요약/키워드: IncP

검색결과 1,380건 처리시간 0.03초

Dietary spray-dried plasma improves intestinal morphology of mated female mice under stress condition

  • Liu, Yanhong;Choe, Jeehwan;Kim, Sheena;Kim, Byeonghyeon;Campbell, Joy M.;Polo, Javier;Crenshaw, Joe D.;Pettigrew, James E.;Song, Minho
    • Journal of Animal Science and Technology
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    • 제60권6호
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    • pp.10.1-10.6
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    • 2018
  • Background: Stress causes inflammation that impairs intestinal barrier function. Dietary spray-dried plasma (SDP) has recognized anti-inflammatory effects and improvement of gut barrier function. Therefore, the purpose of this study was to investigate the effects of dietary SDP on intestinal morphology of mated female mice under stress condition. Results: Villus height, width, and area of small intestines were low on gestation day (GD) 3 or 4 under stress conditions, and higher later (Time, P < 0.05). Crypt depth of colon was low on GD 4 and higher later (Time, P < 0.05). Meanwhile, the SDP treatments improved (P < 0.05) intestinal morphology, indicated by increased villus height, villus width, villus area, and ratio between villus height and crypt depth of small intestines and crypt depth of colon, and by decreased crypt depth of small intestines, compared with the control diet. The SDP treatments also increased (P < 0.05) the number of goblet cells in intestines compared with the control diet. There were no differences between different levels of SDP. Conclusion: Dietary SDP improves intestinal morphology of mated female mice under stress condition.

칡뿌리 추출물을 이용한 천연 모발염색 (The Natural Hair Dyeing using Extracts of the Pueraria thunbergiana Root)

  • 이옥규;윤영민;이현진;안성관
    • 대한화장품학회지
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    • 제36권1호
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    • pp.33-39
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    • 2010
  • 최근 합성 염모제의 부작용들 때문에 인체에 무해한 천연재료를 이용한 염색에 대한 관심이 고조되어 있다. 본 연구에서는 농산 폐기물인 칡뿌리 추출물을 이용해 탈색 모발에 천연 염색을 함으로써 염색에 적절한 염색 시간, 염색시 온도와 매염과 매염제 처리 농도 변화 등에 따른 모발의 염색 정도를 색차계를 통해 조사하였다. 합성 염모제가 가진 화학 물질로 인한 모발 손상에 비해 칡뿌리 추출물을 이용한 모발 염색은 손상도를 낮춰주고 큐티클을 부드럽게 유지시키는 결과를 가져왔다. 칡 추출물만으로 염색한 모발이 가장 어두워짐을 관찰함으로써, 매염제는 염색의 보조 역할을 하는 성분임을 알 수 있었다. 본 연구의 결과를 종합하여 볼 때 칡뿌리 추출물은 합성 염모제에 비해 모발 손상도가 적으며 칡뿌리 추출물을 천연 모발 염모제의 주원료로써 활용가치가 있음을 제안하는 바이다.

Specific Binding of Streptavidin onto the Nonbiofouling Titanium/Titanium Oxide Surface through Surface-Initiated, Atom Transfer Radical Polymerization and Bioconjugation of Biotin

  • Kang, Sung-Min;Lee, Bong-Soo;Kim, Wan-Joong;Choi, In-Sung S.;Kil, Mun-Jae;Jung, Hyuk-Jun;Oh, Eu-Gene
    • Macromolecular Research
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    • 제17권3호
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    • pp.174-180
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    • 2009
  • Chemical modification of titanium/titanium oxide (Ti/$TiO_2$) substrates has recently gained a great deal of attention because of the applications of Ti/$TiO_2$-based materials to biomedical areas. The reported modification methods generally involve passive coating of Ti/$TiO_2$ substrates with protein-resistant materials, and poly(ethylene glycol) (PEG) has proven advantageous for bestowing a nonbiofouling property on the surface of Ti/$TiO_2$. However, the wider applications of Ti/$TiO_2$ based materials to biomedical areas will require the introduction of biologically active moieties onto Ti/$TiO_2$, in addition to nonbiofouling property. In this work, we therefore utilized surface-initiated polymerization to coat the Ti/$TiO_2$ substrates with polymers presenting the nonbiofouling PEG moiety and subsequently conjugated biologically active compounds to the PEG-presenting, polymeric films. Specifically, a Ti/$TiO_2$ surface was chemically modified to present an initiator for atom transfer radical polymerization, and poly(ethylene glycol) methacrylate (pEGMA) was polymerized from the surface. After activation of hydroxyl groups of poly(pEGMA) (pPEGMA) with N,N'-disuccinimidyl carbonate, biotin, a model compound, was conjugated to the pPEGMA films. The reactions were confirmed by infrared spectroscopy, X-ray photoelectron spectroscopy, contact angle goniometry, and ellipsometry. The biospecific binding of target proteins was also utilized to generate micropatterns of proteins on the Ti/$TiO_2$ surface.

Gentiobiose Synthesis from Glucose Using Recombinant $\beta$-Glucosidase from Thermus caldophilus GK24

  • Kim, Tae-Yeon;Lee, Dae-Sil;Shin, Hyun-Jae
    • Biotechnology and Bioprocess Engineering:BBE
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    • 제8권3호
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    • pp.210-212
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    • 2003
  • Recombinant $\beta$-glucosidase from Thermus caldophilus GK24 was easily purified partially by a heat treatment procedure, resulting in 8-fold and recovery yield of 80% from crude enzyme. When the $\beta$-glucosidase was incubated with a 80% glucose solution (w/w), gentiobiose ($\beta$1,6-glucobiose) was the major product in the reaction mixture. The optimal conditions for producing gentiobiose (11% yields of total sugar) were pH 8-9 and 7$0^{\circ}C$ for 72 h.

Tris(2-methoxyphenyl)phosphine as a Highly Active Ligand for the Synthesis of Biaryls by Suzuki Coupling Reaction

  • Kang, Pill-Seong;Ko, Sung-Bo;Ko, Jang-Myoun;Park, Jeong-Ho
    • Bulletin of the Korean Chemical Society
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    • 제30권11호
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    • pp.2697-2700
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    • 2009
  • A $Pd(OAc)_2/(o-MeOPh)_3P$ system has been developed for the catalytic Suzuki coupling of aryl bromides with arylboronic acids. Our catalyst system covers a broad spectrum of commonly available arylboronic acids and aryl bromides to provide biaryls in very good yields. The catalyst system works very well in the synthesis of sterically hindered biaryls.