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Mechanical Properties and Bio-Compatibility of Ti-Nb-Zr-HA Biomaterial Fabricated by Rapid Sintering Using HEMM Powders (고에너지 밀링분말과 급속소결을 이용한 Ti-Nb-Zr-HA 생체복합재의 기계적 성질 및 생체적합성)

  • Park, Sang-Hoon;Woo, Kee-Do;Kim, Sang-Hyuk;Lee, Seung-Min;Kim, Ji-Young;Ko, Hye-Rim;Kim, Sang-Mi
    • Korean Journal of Materials Research
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    • v.21 no.7
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    • pp.384-390
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    • 2011
  • Ti-6Al-4V ELI (Extra Low Interstitial) alloy has been widely used as an alternative to bone due to its excellent biocompatibility. However, it still has many problems, including a high elastic modulus and toxicity. Therefore, nontoxic biomaterials with a low elastic modulus should be developed. However, the fabrication of a uniform coating is challenging. Moreover, the coating layer on Ti and Ti alloy substrates can be peeled off after implantation. To overcome these problems, it is necessary to produce bulk Ti and Ti alloy with hydroxyapatite (HA) composites. In this study, Ti, Nb, and Zr powders, which are biocompatible elements, were milled in a mixing machine (24h) and by planetary mechanical ball milling (1h, 4h, and 6h), respectively. Ti-35%Nb-7%Zr and Ti-35%Nb-7%Zr-10%HA composites were fabricated by spark plasma sintering (SPS) at $1000^{\circ}C$ under 70MPa using mixed and milled powders. The effects of HA addition and milling time on the biocompatibility and physical and mechanical properties of the Ti-35%Nb-7%Zr-(10%HA) alloys have been investigated. $Ti_2O$, CaO, $CaTiO_3$, and $Ti_xP_y$ phases were formed by chemical reaction during sintering. Vickers hardness of the sintered composites increases with increased milling time and by the addition of HA. The biocompatibilty of the HA added Ti-Nb-Zr alloys was improved, but the sintering ability was decreased.

The Quality of Life Analysis in Patients with Cervical Cancer (자궁경부암 환자의 삶의 질 분석)

  • Kim, Yoon-Sook;Kim, Boon-Han
    • Journal of Hospice and Palliative Care
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    • v.7 no.1
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    • pp.8-16
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    • 2004
  • Purpose: The porpose of this descriptive study was grasp the QOL (Quality of Life) of cervix cancer patient and to analysis QOL (Quality of Life) by stage of disease, type of treatment and de me graphic characteristics Methods: Data were collected from 67 patients with cervical cancer from 3 General Hospitals from March 15 to June 4 using The "QOL (Quality of Life)-Cancer Version" inventory made by Ferrell et al (1995). The data were analysed by using SPSS $PC^+$ program including t-test, ANOVA, and Scheffe test. Results: Progressing stage of disease and QOL, the significant between the progressing stage of disease and QOL was significant (F=5.06, P=.003). The degree of difference between the progresstion of the stage of the disease and each item in the test was physical well-being (F=3.97 P=.012), the items of psychological well-being (F=3.91, P=.013), the items of social well-being (F=4.96, P=.004). It show a significant difference, but the item of spiritual well-being (F=1.36, P=.262) was not significant difference. The significance between the type of treatment and QOL was insignificant. The degree of difference between each area of life was the psychological well-being (t=-2.14, P=.037), the social well-being (t=-2.15, P=.036). But the physical well-being (t=-.93, P=.356), the spiritual well-being (t=.73, P=.469) was insignificant. Conclusion: As a result, The QOL of patients with cervical cancer is differentiated by the stage of disease, the type of treatment, and the demographic data. Therefore, there is a need to apply nursing intervention to patients with cervical cancer by considering the stage of disease, the type of treatment, and the demographic data.

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A Study on Behavioral Factors for the Safely of Ambulance Driving (일부지역에서 구급차운전자의 구급차 안전운전 운행행태에 관한 연구)

  • Jo, Jeanman;Lee, Byung-Ju
    • The Korean Journal of Emergency Medical Services
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    • v.1 no.1
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    • pp.100-111
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    • 1997
  • This is the first Korea study to evaluate the effects od the safety of ambulance driving and the occurrence of ambulance traffic accidents and to provide basic informaion for the description of various factors to reduce the ambulance traffic accidents. The major insturment of this study were Krean Self-Analysis Driver Opinionnaire. Questionnaire contains 8 items which measure driver's opinions or attitudes : driving courtesy, emotion, traffic law, speed, vehicle conditions, the use of drugs, high-risk behaviors, and human factors. To take the analysis of data, the total of 350 divers were investigated ambulance divers and others in Taejon City and others (6 City) from 1996. 1. July to 1996. 31. July. The data were analyzed by the descriptive statistics and the logistic regression - path analysis - with SPSS and SAS package program. The result are as follows : 1. There was desirable attitude group(16.2%) and undesirable attitude group(17.6%) on safety ambulance driving. 2. It have suggested that risk factors of ambulance traffic accidents much affected with emotion and speed control on safety ambulance driving < Y(Accdient) = -2.64 + 0.57 $X_1$ (Emotion Control) + 0.30 $X_2$(Seed control) + E > and motor traffic acident much affected with emotion control and high-risk behavior on safety driving < Y(Accident) = -1.11 + 0.33 $X_1$(Emotion Control) + 0.29 $X_2$(High-risk Behvior) + E > 4. The primary emphassis of ambulance drivers was make us realized that improthatnt factors on safety ambulance driving were 1)making way for emergent ambulance, 2)driver's career, 3)The ability of emergency medical technics, and the knowledge or under standing of ambulance way difficut(or easy) of accdess. 5. Almost 96.6% of respondents have agreed to necessity of emergency medical technics for ambulance drivers. 6. Almost 94.6% of respondents have consented to necessity of emergtency medical technicians for ambulance driving. 7. It have suggested that the proportion of traffic accident proportion by desitable attitude group(16.7%) was much less than that of undesirable attitude group(30.8%) on safety ambulance driving(P < 0.05)/Ps) Accidents are unplanned, unforesen incidents which can lead to harmful or unfortunate outcomes, Collisons are not accidents, since the basic cause of the majority of collisons invovles high-risk human behavior. Although there are many factors which contribute to accident causation, four basic factors seem to predominate in most traffic related situations. These four factors include: the human factor, the vehicle factor, the environmental factors and destination factor(Peto G. et al. 1995).

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The Internationalization of Korean Software-related New Venture on Resource Based Perspectives - The Bundle of Tangible and Intangible Resources - (자원기반관점에서의 한국 소프트웨어개발 벤처기업의 국제화 - 가시적 자원과 비가시적 자원의 조합을 중심으로 -)

  • Lee, Keun-Hee;Kim, Jung-Po
    • International Area Studies Review
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    • v.13 no.2
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    • pp.393-416
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    • 2009
  • This paper explores the technology resource-based determinants influencing internationalization performance of Korean software-related new ventures. On the ground of the study by Zahra et al.(2003), this paper aims to test empirically in Korea how interaction effects of tangible and intangible technological resources, as firm capability, are related to software new ventures' internationalization performance. The test results shows that intangible technological resource represented by R&D intensity is not significantly related to internationalization performance, but reveals that intangible technological resource represented by strength of technological cooperation network and technological reputation is positively and significantly associated with internationalization performance. Internationalization performance is more significantly and positively associated with the interactions of tangible technological resource and intangible technological resource than those resources respectively. The implication for the findings in the paper is that cutting edge technological capability of software new ventures can be more closely associated with internationalization performance if those resources are fully utilized or leveraged by intangible resources acquired by cooperation with local networks and created through technological reputation of new ventures.

3D Porous Foam-based Triboelectric Nanogenerators for Energy Harvesting (3차원 기공구조를 이용한 정전기반 에너지 하베스팅 나노발전기 소자제조)

  • Jeon, Sangheon;Jeong, Jeonghwa;Hong, Suck Won
    • Journal of the Microelectronics and Packaging Society
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    • v.26 no.1
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    • pp.9-15
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    • 2019
  • Here, we present a facile route to fabricate a vertically stacked 3D porous structure-based triboelectric nanogenerator (TENG) that can be used to harvest energy from the friction in a repetitive contact-separation mode. The unit component of TENG consists of thin Al foil electrodes integrated with microstructured 3D foams such as Ni, Cu, and polyurethane (PU), which provide advantageous tribo-surfaces specifically to increase the friction area to the elastomeric counter contact surfaces (i.e., polydimethylsiloxane, PDMS). The periodic contact/separation-induced triboelectric power generation from a single unit of the 3D porous structure-based TENG was up to $0.74mW/m^2$ under a mild condition. To demonstrate the potential applications of our approach, we applied our TENGs to small-scale devices, operating 48 LEDs and capacitors. We envision that this energy harvesting technology can be expanded to the applications of sustainably operating portable electronic devices in a simple and cost-effective manner by effectively harvesting wasted energy resources from the environment.

Exploring the Applicability of Protocol to Improve Curriculum Literacy for Special Education Pre-Teachers (예비특수교사들의 특수교육교육과정 문해력 향상을 위한 프로토콜 적용 가능성 탐색)

  • Lee, Okin;Park, Eun-Young
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.3
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    • pp.179-185
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    • 2021
  • We performed to explore the applicability of protocol to improve the curriculum literacy for special education pre-teachers. For this, protocol of Park et al (2018), which can be used in the educational field, was partially modified and applied to enhance the special education curriculum expertise of pre-teachers. The literacy protocol of the special education curriculum was applied as Protocols 1 and 2, and Protocol 1 was focused on adaptation the 2015 special education curriculum and understanding literacy. Protocol 2 consisted of reorganizing the subject level centering on the five subjects presented in the special education curriculum, and establishing an integrated theme setting and reorganization plan. We applied the research design during a total of 15 weeks of special education curriculum subjects. The class format was flipped learning (e.g, pre-video lectures, theory lectures (E-Sheets), and learner-led activities (W-Sheets) for each topic was carried out. We found that pre-teachers' thought that the academic achievement and satisfaction of students with disabilities could be increased by adaptation the curriculum. Pre-teachers reported that the experience of reorganizing each subject/intersection helped improve their literacy but found it difficult.

Solid-state synthesis of yttrium oxyfluoride powders and their application to plasma spray coating (옥시불화이트륨 분말의 고상합성 및 플라즈마 스프레이 코팅 적용)

  • Lee, Jung-Il;Kim, Young-Ju;Chae, Hui Ra;Kim, Yun Jeong;Park, Seong Ju;Sin, Gyoung Seon;Ha, Tae Bin;Kim, Ji Hyeon;Jeong, Gu Hun;Ryu, Jeong Ho
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.31 no.6
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    • pp.276-281
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    • 2021
  • In order to manufacture a semiconductor circuit, etching, cleaning, and deposition processes are repeated. During these processes, the inside of the processing chamber is exposed to corrosive plasma. Therefore, the coating of the inner wall of the semiconductor equipment with a plasma-resistant material has been attempted to minimize the etching of the coating and particle contaminant generation. In this study, we synthesized yttrium oxyfluoride (YOF) powder by a solid-state reaction using Y2O3 and YF3 as raw materials. Mixing ratio of the Y2O3 and YF3 was varied from 1.0:1.0 to 1.0:1.6. Effects of the mixing ratio on crystal structure and microstructure of the synthesized YOF powder were investigated using XRD and FE-SEM. The synthesized YOF powder was successfully applied to plasma spray coating process on Al substrate.

Homogenization of Plastic Behavior of Metallic Particle/Epoxy Composite Adhesive for Cold Spray Deposition (저온 분사 공정을 위한 금속입자/에폭시 복합재료 접착제의 소성 거동의 균질화 기법 연구)

  • Yong-Jun Cho;Jae-An Jeon;Kinal Kim;Po-Lun Feng;Steven Nutt;Sang-Eui Lee
    • Composites Research
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    • v.36 no.3
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    • pp.199-204
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    • 2023
  • A combination of a metallic mesh and an adhesive layer of metallic particle/epoxy composite was introduced as an intermediate layer to enhance the adhesion between cold-sprayed particles and fiber-reinforced composites (FRCs). Aluminum was considered for both the metallic particles in the adhesive and the metallic mesh. To predict the mechanical characteristics of the intermediate bond layer under a high strain rate, the properties of the adhesive layer needed to be calculated or measured. Therefore, in this study, the Al particle/epoxy adhesive was homogenized by using a rule of mixture. To verify the homogenization, the penetration depth, and the thickness decrease after the cold spray deposition from the undeformed surface, was monitored with FE analysis and compared with experimental observation. The comparison displayed that the penetration depth was comparable to the diameters of one cold spray particle, and thus the homogenization approach can be reasonable for the prediction of the stress level of particulate polymer composite interlayer under a high strain rate for cold spray processing.

Estimation of Glomerular Filtration Rate from Plasma Creatinine and Height in Children (소아에서 신장과 혈장 Creatinine 농도를 이용한 사구체여관율 측정)

  • Kim, Jeong-Lan;Park, Yong-Hoon;Hah, Jeong-Ok
    • Journal of Yeungnam Medical Science
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    • v.5 no.1
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    • pp.93-100
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    • 1988
  • In clinical practice, creatinine clearance(Ccr) remains the most commonly used laboratory assessment of glomerular function despite methodological and technical problems of urine collection. Schwartz et al. in 1976, reported that an accurate estimate of glomerular filtration rate(GFR) could be obtained from the simple determinations of plasma creatinine(Pcr) and body length(L) : GFR($m{\ell}/min/1.73m^2$=k L(cm)/Pcr(mg/$100m{\ell}$), (k=constant). The subject of this study were ill children admitted to our pediatric department from July, 1985 to June, 1987 and they were divided into three groups; group I, from 1 to 5 years old, group II, from 6 to 10 years old, group III. from 11 to 15 years old. The results were as following ; 1) Measured creatinine clearance($Ccr_M$, $m{\ell}/min/1.73m^2$) were $109.73{\pm}9.97$ in group I, $108.26{\pm}9.02$ in group II, $96.20{\pm}4.72$ in group III and $105.48{\pm}5.23$ in all age group. 2) Measured k($k_M$) obtained from $Ccr_M=k$ Ht/Pcr were $0.49{\pm}0.03$ in group I, $0.48{\pm}0.02$ in group II, $0.43{\pm}0.02$ in group III, and $0.47{\pm}0.02$ in all age group.(Ht ; height) 3) Linear equations and correlation coefficients between Ht/Pcr(x) and Ccr(y) were y=0.822x-65.63(r=0.99) in group I, y=0.61x-23.46(r=0.72) in group II, y=0.18x+54.44(r=0.54) in group III and y=0.58x-22.13(r=0.81) in all age group. 4) $Ccr_E$ was again estiamted from linear equations between Ht/Pcr and $Ccr_M$ and $k_E$ was calculated with Ht/Pcr and $Ccr_E$ were $0.48{\pm}0.01$ in group I, $0.49{\pm}0.01$in group II, $0.43{\pm}0.01$ in group III and $0.47{\pm}0.00$ in all age group. 5) Consistant values of $k_E$ and $k_M$ were highly significant as 95~97.5% in group I and II, 90~95% in group III and 97.5~99% in all age group. In summary, we could estimate GFR with height, plasma creatinine and measured k($k_M$) according to the age in easy and rapid way.

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Radiographic change of grafted sinus floor after maxillary sinus floor elevation and placement of dental implant (상악동저 거상술과 임플란트 식립 후 상악동저 변화에 대한 연구)

  • Cho, Sang-Ho;Kim, Ok-Su
    • Journal of Periodontal and Implant Science
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    • v.36 no.2
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    • pp.345-359
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    • 2006
  • Loss of maxillary molar teeth leads to rapid loss of crestal bone and inferior expansion of the maxillary sinus floor (secondary pneumatization). Rehabilitation of the site with osseointegrated dental implants often represents a clinical challenge because of the insufficient bone volume resulted from this phenomenon. Boyne & James proposed the classic procedure for maxillary sinus floor elevation entails preparation of a trap door including the Schneiderian membrane in the lateral sinus wall. Summers proposed another non-invasive method using a set of osteotome and the osteotome sinus floor elevation (OSFE) was proposed for implant sites with at least 5-6mm of bone between the alveolar crest and the maxillary sinus floor. The change of grafted material in maxillary sinus is important for implant survival and the evaluation of graft height after maxillary sinus floor elevation is composed of histologic evaluation and radiomorphometric evaluation. The aim of the present study was radiographically evaluate the graft height change after maxillary sinus floor elevation and the influence of the graft material type in height change and the bone remodeling of grafts in sinus. A total of 59 patients (28 in lateral approach and 31 in crestal approach) who underwent maxillary sinus floor elevation composed of lateral approach and crestal approach were radiographically followed for up to about 48 months. Change in sinusgraft height were calculated with respect to implant length (IL) and grafted sinus height(BL). It was evaluated the change of the graft height according to time, the influence of the approach technique (staged approach and simultaneous approach) in lateral approach to change of the graft height, and the influence of the type of graft materials to change of the graft height. Patients were divided into three class based on the height of the grafted sinus floor relative to the implant apex and evaluated the proportion change of that class (Class I, in which the grafted sinus floor was above the implant apex; Class II, in which the implant apex was level with the grafted sinus floor; and Class III, in which the grafted sinus floor was below the implant apex). And it was evaluated th bone remodeling in sinus during 12 months using SGRl(by $Br\ddot{a}gger$ et al). The result was like that; Sinus graft height decreased significantly in both lateral approach and crestal approach in first 12 months (p$MBCP^{TM}$ had minimum height loss. Class III and Class II was increased by time in both lateral and crestal approach and Class I was decreased by time. SGRI was increased statistically significantly from baseline to 3 months and 3 months(p<0.05) to 12 months(p$ICB^{(R)}$ single use, more reduction of sinusgraft height was appeared. Therefore we speculated that the mixture of graft materials is preferable as a reduction of graft materials. Increasing of the SGRI as time goes by explains the stability of implant, but additional histologic or computed tomographic study will be needed for accurate conclusion. From the radiographic evaluation, we come to know that placement of dental implant with sinus floor elevation is an effective procedure in atrophic maxillary reconstruction.