• Microbiology and Biotechnology Letters
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• v.29 no.4
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• pp.240-247
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• 2001

The effect of microsparged aeration in mammalian cell bioreactor on the oxygen transfer rate and cell viability was studied. The microspargers with differ- ent micron-sized pores were used to supply oxygen to the medium. The oxygen transfer coefficients (k$_{L}$a) measured in the bioreactor were markedly increased, which is due to the increase of the contacting area between air bubbles and liquid medium when the pore size of microsparger decreases. When the impellers of two different types (square-pitch marine impeller and $45^{\circ}$ pitched flat blade impeller) were used for agitation, the k$_{L}$a values were slightly higher with the marine impeller than with the blade impeller. The detrimental effect of direct gas sparging with microsparger on mammalian cells was investigated in bubble columns with various air flow rates and different pore sized microspargers. The first-order cell death rate constant ($k_{d}$ /7) was shown to be directly proportional to the air flow rate and inversely proportional to the pore size. During the cultivation of hybridoma cells using microsparger with the pore size of $0.57\mu$m in the mammalian cell culture bioreactor, the continuous sparging caused the cell death and suppressed the cell growth. However, cells grew normally and cell viability was maintained above 90% in the logarithmic phase when the air was intermittently sparked in order to maintain the dissolved oxygen level above 20%.

• Journal of computational fluids engineering
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• v.8 no.4
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• pp.50-57
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• 2003

Cross-flow fans are widely used in various applications, due to their large capacity of mass flow and size compactness. The flow field of the cross-flow fan is, however, complex and has many design parameters. Thus, the general design guide has not been sufficiently established yet and the design strategies of cross-flow fans have been mostly based on experiments. In the present study, the performance and their two-dimensional flow characteristics are numerically analyzed by using the STAR-CD(commercial computational fluid dynamics code). The simulation is done by varying the several design parameters such as the impeller blade shapes and the gap between the stabilizer and impeller. The computational results are compared with the experimental data at the fan outlet region. Finally, some helpful guides for the optimum design of cross-flow fans are proposed.

• 유체기계공업학회:학술대회논문집
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• 2000.12a
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• pp.99-103
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• 2000

This paper describes the development of standard series for turbo blowers. In mass production system, it is very required to standardize blowers to improve the productivity of ordering, estimating, manufacturing. To standardize blowers, we performed researches on the effects of $b_1$(impeller inlet width), $b_2$(impeller outlet width), ${\beta}_1$(blade inlet angle), ${\beta}_2$(blade outlet angle), Z(number of blades) of impellers and geometry of casing experimentally. Through this study, we chose the several best model of turbo blowers with high efficiency and low noise, which represent each specific speed series 63, 80, 100, 125, 160, 200, 250, 315. After the development of such standardized blowers, the test results are used to prepare the fan geometry and performance database for a selection software.

• The KSFM Journal of Fluid Machinery
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• v.13 no.2
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• pp.59-64
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• 2010

A design method of Sirocco fan is developed for constructing 3-D impeller and scroll geometries, and for predicting both the aerodynamic performance and the noise characteristics of the designed fan. The aerodynamic blading design of fan is conducted by blade angle, camber line determinations and airfoil thickness distribution, and then the scroll geometry of fan is designed by using logarithmic spiral. The aerodynamic performance of designed fan is predicted by the meanline analysis with flow blockage, slip and pressure loss correlations. Based on the predicted performance data, fan noise is predicted by two models for cutoff frequency and broadband noise sources. The present predictions for the performance and the noise level of actual fans are well agreed with measurement results.

• 한국전산유체공학회:학술대회논문집
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• 2010.05a
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• pp.142-146
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• 2010

This study presents the design of small size turbo-compressor to increase the performance using computational fluid analysis. A three dimensional computation was conducted changing the main parameters of impeller blade and diffuser shape, respectively, and the design was performed on a basis analysis of result of that. As a result, the Improved shapes show the increase of efficiency in comparison with the existing shape. This study will be used as useful reference data to establish the design concept of the small size turbo-compressor and to improve its performance.

• 유체기계공업학회:학술대회논문집
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• 2005.12a
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• pp.373-377
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• 2005

The Performance of in-line duct fan depends on the design parameters of impeller and guide vane. such as sweep back angle of impeller, the number of blades, outlet blade angle, guide vane angle etc. In this experimental study total four kinds of impellers having different sweep back angles, $90^{\circ},\;72.5^{\circ},\;55^{\circ},\;37.5^{\circ}$ with 8 guide vanes, different the number of blades, 6ea, 8ea, 10ea, 12ea, different kinds of outlet blade angles, $30^{\circ},\;45^{\circ}.\;60^{\circ}$ and different kinds of guide vane angles, $15^{\circ},\;30^{\circ},\;45^{\circ}$ were selected and their performance measured to investigate the effects of them. The results were non-dimensionalized to compare their performance.

• The KSFM Journal of Fluid Machinery
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• v.13 no.6
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• pp.71-76
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• 2010

This study has investigated numerically and experimentally the flow characteristic of air-cooling fan for transmission oil cooler in the large-size diesel engine. Impellers of cooler were composed of eight normal-scale and eight small-scale blades in the zig-zag pattern. In order to increase the discharge pressure of cooling fan, turbo type of fan blade is proposed in the impeller for transmission oil cooler. The fluidic performance of cooling fan has been estimated numerically by using the commercial code and experimentally carried out with reference on AMCA Standard 210-99. As a result, it is confirmed that the numerical result for performance curve is in good agreement with experimental data.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.14 no.9 s.90
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• pp.785-791
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• 2004

The objective of this research is to suggest anoise prediction method for a centrifugal compressor. It is focused on the Blade Passing Frequency component which is regarded as the main part of the rotating impeller noise. Navier-Stokes solver is used to simulate the flow-field of the centrifugal compressor, and the time-dependent pressure data are calculated to perform the near-field noise prediction by using Ffowcs Williams - Hawkings formulation. Indirect Boundary Element Method is applied to consider the noise propagation effect. Pressure fluctuations of the inlet and the outlet in the centrifugal compressor impeller are presented and the sound pressure level prediction results are compared with the experimental data.

• 한국전산유체공학회:학술대회논문집
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• 2003.08a
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• pp.165-170
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• 2003

Centrifugal blowers are widely used for air handling units in industry applications. The blower has a centrifugal impeller and a scroll casing including a driving component such as an electric motor. The impeller takes forward or backward blades to induce flows into the blower. Comprehensive investigation according to the two kinds of blades is systematically carried out for a guidance of design. It is observed that flow rate of the blower with forward blades is larger than that of the system with backward blades. The reason is due to larger velocity from the rotating forward blades and the tendency is validated by a parallel experiment with a wind tunnel. Numerical analysis for the system shows detail information inside the blades and the casing. A series of figures to show the flow details offers deep understanding of a centrifugal blower with different blades.

• International Journal of Fluid Machinery and Systems
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• v.2 no.1
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• pp.21-30
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• 2009

Slurry wear with sand particles in rivers is a serious problem for pump operation. Therefore, a technique to predict wear volume loss is required for selecting wear resistant materials and determining specifications for the maintenance period. This paper reports a method for predicting the wear depth distribution on the blade of an impeller. Slurry wear tests of an aluminum pump impeller were conducted. Prediction results of wear depth distribution approximately correspond with the results of slurry wear tests. This technique is useful for industrial application.