• Title/Summary/Keyword: Immune Performance

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Spray Dried Animal Plasma as an Alternative to Antibiotics in Weanling Pigs - A Review -

  • Torrallardona, David
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.1
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    • pp.131-148
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    • 2010
  • Piglet health at weaning is compromised due to several stress factors. Following the ban of antibiotic growth promoters new alternatives are required to control these problems. This paper reviews the evidence available for the use of spray dried animal plasma (SDAP) as an alternative to antibiotics in weaning pigs. Data from 75 trials in 43 publications involving over 12,000 piglets (mean values) have been used to calculate the performance responses of piglets according to several factors including SDAP origin, protein source from the control diet being replaced, dose of inclusion, age and weight of the piglets at weaning, sanitary conditions and simultaneous use or not of medication. Although the use of SDAP of all origins results in positive responses, it appears that plasma from porcine origin has the highest efficacy. This could be explained by the specificity of its IgG against porcine pathogens. During the first week post-weaning the response to plasma appears to increase with the inclusion dose, although over the two-week pre-starter period an optimal inclusion level of 4-8% is suggested. SDAP improves feed efficiency more markedly when the piglets are challenged with an experimental infection or when feed does not contain medication, which could be indicative of a lower expenditure of energy and nutrients to build an immune response against the challenge. There is evidence supporting that SDAP IgG and other bioactive substances therein prevent the binding of pathogens to the gut wall and reduce the incidence of diarrhoea in the post-weaning phase. Overall, plasma can be postulated as an excellent alternative to in-feed antimicrobials for piglets in the post-weaning phase.

An Optimal Reliability-Redundancy Allocation Problem by using Hybrid Parallel Genetic Algorithm (하이브리드 병렬 유전자 알고리즘을 이용한 최적 신뢰도-중복 할당 문제)

  • Kim, Ki-Tae;Jeon, Geon-Wook
    • IE interfaces
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    • v.23 no.2
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    • pp.147-155
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    • 2010
  • Reliability allocation is defined as a problem of determination of the reliability for subsystems and components to achieve target system reliability. The determination of both optimal component reliability and the number of component redundancy allowing mixed components to maximize the system reliability under resource constraints is called reliability-redundancy allocation problem(RAP). The main objective of this study is to suggest a mathematical programming model and a hybrid parallel genetic algorithm(HPGA) for reliability-redundancy allocation problem that decides both optimal component reliability and the number of component redundancy to maximize the system reliability under cost and weight constraints. The global optimal solutions of each example are obtained by using CPLEX 11.1. The component structure, reliability, cost, and weight were computed by using HPGA and compared the results of existing metaheuristic such as Genetic Algoritm(GA), Tabu Search(TS), Ant Colony Optimization(ACO), Immune Algorithm(IA) and also evaluated performance of HPGA. The result of suggested algorithm gives the same or better solutions when compared with existing algorithms, because the suggested algorithm could paratactically evolved by operating several sub-populations and improve solution through swap, 2-opt, and interchange processes. In order to calculate the improvement of reliability for existing studies and suggested algorithm, a maximum possible improvement(MPI) was applied in this study.

Improvement of Electrostatic Discharge (ESD) Protection Performance through Structure Modification of N-Type Silicon Controlled Rectifier Device (N형 실리콘 제어 정류기 소자의 구조 변형을 통한 정전기 보호성능의 향상에 대한 연구)

  • Yang, Jun-Won;Seo, Yong-Jin
    • Journal of Satellite, Information and Communications
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    • v.8 no.4
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    • pp.124-129
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    • 2013
  • An electrostatic discharge (ESD) protection device, so called, N-type SCR with P-type MOSFET pass structure (NSCR_PPS), was analyzed for high voltage I/O applications. A conventional NSCR_PPS device shows typical SCR-like characteristics with extremely low snapback holding voltage, which may cause latch-up problem during normal operation. However, a modified NSCR_PPS device with counter pocket source(CPS) and partial p-type well(PPW) structure demonstrates highly latch-up immune current-voltage characteristics.

Weighted Voting Game and Stochastic Learning Based Certificate Revocation for the Mobile Ad-hoc Network (이동 애드 혹 네트워크 환경에서 가중투표게임과 확률러닝을 이용한 악의적인 노드의 인증서 폐지 기법)

  • Kim, Min Jung;Kim, Sung Wook
    • KIPS Transactions on Computer and Communication Systems
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    • v.6 no.7
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    • pp.315-320
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    • 2017
  • In this paper, I design a new scheme that is immune to malicious attack based on the weighted voting game. By using stochastic learning, the proposed scheme can revoke the certification of malicious node. Through the revocation process, the proposed scheme can effectively adapt the dynamic Mobile Ad hoc network situation. Simulation results clearly indicate that the developed scheme has better performance than other existing schemes under widely diverse network environments.

Screening and Purification of an Antimicrobial Peptide from the Gill of the Manila Clam Ruditapes philippinarum (바지락(Ruditapes philippinarum) 아가미로부터 항균 펩타이드의 탐색 및 정제)

  • Seo, Jung-Kil
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.49 no.2
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    • pp.137-145
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    • 2016
  • This study screened the biological activity of an acidified gill extract of the Manila clam Ruditapes philippinarum including antimicrobial, hemolytic, membrane permeabilization, and DNA-binding activity, and purified the antimicrobial material. The acidified gill extract showed potent antimicrobial activity against Bacillus subtilis and Escherichia coli without significant hemolytic activity, but showed no membrane permeabilization or DNA-binding ability. An antimicrobial material was purified from the acidified gill extract using C18 reversed-phase and cation-exchange high-performance liquid chromatography (HPLC). Treatment of the purified material with trypsin completely abolished all of the antibacterial activity against Bacillus subtilis, suggesting that the purified material is a proteinaceous antibiotic. The molecular weight of the purified material was 2571.9 Da, but no primary structural information was obtained due to N-terminal blocking. A future study should confirm the primary structure. Our results suggest that the Manila clam gill contains proteinaceous antibiotics that have a role in first-line defense. This information could be used to better understand the Manila clam innate immune system.

Influence of Ligustrum lucidum and Schisandra chinensis Fruits on Antioxidative Metabolism and Immunological Parameters of Layer Chicks

  • Ma, Deying;Liu, Yuqin;Liu, Shengwang;Li, Qundao;Shan, Anshan
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.9
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    • pp.1438-1443
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    • 2007
  • The experiment was conducted to evaluate the effects of Ligustrum lucidum (LL) and Schisandra chinensis (SC) on the growth, antioxidative metabolism and immunity of laying strain male chicks. The results showed that diets supplemented with 1% of either LL or SC had no effects on the growth performance of chicks compared with the control. Furthermore, both LL and SC significantly reduced malondialdehyde (MDA) concentration of serum and heart of chicks (p<0.05). In addition, superoxide dismutase (SOD) activity of serum of the birds was significantly elevated by supplementation with SC (p<0.05). Glutathione reductase (GR) activity of heart and serum of the birds was significantly elevated by supplementation with LL or SC (p<0.05). LL supplementation significantly elevated antibody values against Newcastle Disease virus (NDV)(p<0.05) and lymphoblastogenesis (p<0.05) of the birds. The results suggest that diets supplemented with 1% of either LL or SC may improve immune function and antioxidant status of chicks.

Real-Time Implementation of Power Frequency Estimation Algorithm Based on a Three-Level Discrete Fourier Transform (3레벨 DFT 기반 계통주파수 측정 알고리즘의 실시간 구현에 관한 연구)

  • Moon, JoonHyuck;son, DaeHee;Song, JiHyun;Song, MyeongHoon;Lee, SeungHee;Kang, SangHee;Nam, SoonRyul
    • Proceedings of the KIEE Conference
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    • 2015.07a
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    • pp.579-580
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    • 2015
  • Power frequency is one of important operational parameters evaluating reliability, stability, and measuring efficiency of power. Therefore, an accurate and fast estimate of the power frequency is required. The magnitude gains of cosine and sine filters become different when the power frequency is deviated from the nominal value. The proposed algorithm estimates the power frequency based on this. To demonstrate the performance of the proposed algorithm, RTDS and DSP are used. The simulation results show that the algorithm has not only a high level of robustness but also high measurement accuracy over a wide range of frequency changes. In addition, the algorithm was immune to harmonics and noise.

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Dietary Manipulation of Lean Tissue Deposition in Broiler Chickens

  • Choct, M.;Naylor, A.J.;Oddy, V.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.18 no.5
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    • pp.692-698
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    • 2005
  • Two experiments were conducted to examine the effect of graded levels of dietary chromium and leucine, and different fat sources on performance and body composition of broiler chickens. The results showed that chromium picolinate at 0.5 ppm significantly (p<0.05) lowered the carcass fat level. Gut weight and carcass water content were increased as a result of chromium treatment. Body weight, plucked weight, carcass weight, abdominal fat pad weight, breast yield and feed efficiency were unaffected by chromium treatment. Leucine did not interact with chromium to effect lean growth. Dietary leucine above the recommended maintenance level (1.2% of diet) markedly (p<0.001) reduced the breast muscle yield. The addition of fish oil to broiler diets reduced (p<0.05) the abdominal fat pad weights compared to birds on linseed diets. Fish oil is believed to improve lean growth through the effects of long chain polyunsaturated fatty acids in lowering the very low-density lipoprotein levels and triglyceride in the blood, in the meantime increasing glucose uptake into the muscle tissue in blood and by minimizing the negative impact of the immune system on protein breakdown. The amount of fat in the diet (2% or 4%) did not affect body composition.

Gut Health of Pigs: Challenge Models and Response Criteria with a Critical Analysis of the Effectiveness of Selected Feed Additives - A Review

  • Adewole, D.I.;Kim, I.H.;Nyachoti, C.M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.7
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    • pp.909-924
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    • 2016
  • The gut is the largest organ that helps with the immune function. Gut health, especially in young pigs has a significant benefit to health and performance. In an attempt to maintain and enhance intestinal health in pigs and improve productivity in the absence of in-feed antibiotics, researchers have evaluated a wide range of feed additives. Some of these additives such as zinc oxide, copper sulphate, egg yolk antibodies, mannan-oligosaccharides and spray dried porcine plasma and their effectiveness are discussed in this review. One approach to evaluate the effectiveness of these additives in vivo is to use an appropriate disease challenge model. Over the years, researchers have used a number of challenge models which include the use of specific strains of enterotoxigenic Escherichia coli, bacteria lipopolysaccharide challenge, oral challenge with Salmonella enteric serotype Typhimurium, sanitation challenge, and Lawsonia intercellularis challenge. These challenge models together with the criteria used to evaluate the responses of the animals to them are also discussed in this review.

High-Accuracy Digital-to-Analog Actuators Using Load Springs Compensating Fabrication Errors (제조공정 오차보상용 보정 탄성체를 이용한고정도 디지털-아날로그 구동기)

  • Han, Won;Lee, Won-Chul;Cho, Young-Ho
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.32 no.10
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    • pp.823-830
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    • 2008
  • We present a high-accuracy digital-to-analog (DA) actuator using a load spring, specially designed to compensate the output displacement errors caused by fabrication errors. The compensated linear DA actuator is capable to change the slope of input-output modulation line in order to compensate fabrication errors. We design, fabricate, and characterize three different prototypes: one uncompensated design and two compensated designs respectively for a specific value and for a given range of fabrication error. The compensated linear DA actuators show the output displacement errors of $-0.20{\pm}0.23{\mu}m\;and\;-0.13{\pm}0.18{\mu}m$, respectively, reduced by 64.3% and 76.8% of the output displacement error, $0.56{\pm}0.20{\mu}m$, produced by the conventional uncompensated linear DA actuator. We experimentally verify the fabrication error compensation capability of the present compensated linear DA actuators, thus demonstrating high-accuracy actuation performance immune to fabrication errors.