• Title/Summary/Keyword: Imine

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Enantioselective Recognition of Amino Alcohols and Amino Acids by Chiral Binol-Based Aldehydes with Conjugated Rings at the Hydrogen Bonding Donor Sites

  • Kim, Ji-Young;Nandhakumar, Raju;Kim, Kwan-Mook
    • Bulletin of the Korean Chemical Society
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    • v.32 no.4
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    • pp.1263-1267
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    • 2011

  • Novel binol-based uryl and guanidinium receptors having higher ring conjugation at the periphery of the hydrogen bonding donor sites have been synthesized and utilized to study the enantioselective recognition of 1,2-aminoalcohols and chirality conversion of natural amino acids via imine bond formation. There is a remarkable decrease in the stereoselectivites as the conjugation increases at the periphery of hydrogen bonding donor sites. The guanidinium-based receptors show more selectivity towards the amino alcohol than that of the uryl based ones due to its charge reinforced hydrogen bonds. The conversion efficiency of L-amino acids to Damino acids by the uryl-based receptors is higher than that of the guanidinium-based ones.

  • https://doi.org/10.5012/bkcs.2011.32.4.1263 인용 PDF KSCI

Antimicrobial Activity of Some Schiff Bases Derived from Benzoin, Salicylaldehyde, Aminophenol and 2,4 Dinitrophenyl Hydrazine

  • Jesmin, Mele;Ali, M. Mohsin;Salahuddin, M.S.;Habib, M. Rowshanul;Khanam, Jahan Ara
    • Mycobiology
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    • v.36 no.1
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    • pp.70-73
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    • 2008

  • The antibacterial and antifungal activities of three schiff bases were evaluated against some pathogenic bacteria and fungi. Parallel experiments were also carried out with standard drugs (Kanamycin for bacteria and Nystatin for fungi). Two compounds [N-(1-phenyl-2-hydroxy-2phenylethylidine)-2',4' dinitrophenyl hydrazine, abbreviated as PDH and N-(2-hydroxy benzylidine)-2'-hydroxy imine, abbreviated as HHP] showed significant antimicrobial activities. The rest one [N-(l-phenyl 2-hydroxy-2 phenyl ethylidine) 2'-hydroxy phenyl imine, abbreviated as PHP] showed moderate activity. All these three compounds were found to possess pronounced cytotoxic effect. These compounds can be considered as potent antimicrobial agents.

  • https://doi.org/10.4489/MYCO.2008.36.1.070 인용 PDF KSCI

Synthesis of Pyrimidines and Heteroannulated Pyrimidine Ring Systems (Pyrimidines과 pyrimidine의 헤테로고리의 합성)

  • Mohammed, F.K.;Badrey, M.G.
    • Journal of the Korean Chemical Society
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    • v.55 no.2
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    • pp.218-229
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    • 2011

  • We have involved the imine compound 1 in condensations with various nitrogenous reagents including hydrazine hydrate to construct differently substituted pyrimidines. One of the pyrimidines so obtained was further subjected to interactions with different reagents such as propionic acid, formic acid, ethyl chloroformate, acdetic anhydride, carbon disulphide, cyanogene bromide, triflauroacetic acid and ethyl chloroacetate which resulted in the formation of annulated heterocyclic systems as pairs of isomers in most cases as a result of Dimroth-type rearrangement.

  • https://doi.org/10.5012/jkcs.2011.55.2.218 인용 PDF KSCI KPUBS HTML

Synthesis of Pyrrolo[2,3-c]acridines

  • Munawar Ali Munawar;Paul W. Groundwater
    • Bulletin of the Korean Chemical Society
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    • v.20 no.4
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    • pp.456-458
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    • 1999

  • The synthesis of 6-amino-3-benzylpyrrolo[2,3-c]acridine (9) and its 8,9-dimethoxy derivative (10) from N-benzyl-4,5,6,7-tetrahydroindol-4-one and anthranilonitriles, via imine formation followed by cyclization and aromatisation, is described.

  • https://doi.org/10.5012/bkcs.1999.20.4.456 인용 PDF