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http://dx.doi.org/10.5012/jkcs.2011.55.2.218

Synthesis of Pyrimidines and Heteroannulated Pyrimidine Ring Systems  

Mohammed, F.K. (Chemistry department, Faculty of Science, Fayoum University)
Badrey, M.G. (Chemistry department, Faculty of Science, Fayoum University)
Publication Information
Journal of the Korean Chemical Society / v.55, no.2, 2011 , pp. 218-229 More about this Journal
Abstract
We have involved the imine compound 1 in condensations with various nitrogenous reagents including hydrazine hydrate to construct differently substituted pyrimidines. One of the pyrimidines so obtained was further subjected to interactions with different reagents such as propionic acid, formic acid, ethyl chloroformate, acdetic anhydride, carbon disulphide, cyanogene bromide, triflauroacetic acid and ethyl chloroacetate which resulted in the formation of annulated heterocyclic systems as pairs of isomers in most cases as a result of Dimroth-type rearrangement.
Keywords
Pyrimidine; Triazolopyrimidine; Triazinopyrimidine; Benzopyran derivatives;
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