Mycobiology

  • 제36권1호
  • /
  • Pages.70-73
  • /
  • 2008
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  • 1229-8093(pISSN)
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  • 2092-9323(eISSN)
한국균학회 (The Korean Society of Mycology)
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Antimicrobial Activity of Some Schiff Bases Derived from Benzoin, Salicylaldehyde, Aminophenol and 2,4 Dinitrophenyl Hydrazine

  • Jesmin, Mele (Department of Applied Chemistry and Chemical Technology, Rajshahi University) ;
  • Ali, M. Mohsin (Department of Applied Chemistry and Chemical Technology, Rajshahi University) ;
  • Salahuddin, M.S. (Department of Biochemistry and Molecular Biology, Rajshahi University) ;
  • Habib, M. Rowshanul (Department of Biochemistry and Molecular Biology, Rajshahi University) ;
  • Khanam, Jahan Ara (Department of Biochemistry and Molecular Biology, Rajshahi University)
  • 발행 : 2008.03.31
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초록

The antibacterial and antifungal activities of three schiff bases were evaluated against some pathogenic bacteria and fungi. Parallel experiments were also carried out with standard drugs (Kanamycin for bacteria and Nystatin for fungi). Two compounds [N-(1-phenyl-2-hydroxy-2phenylethylidine)-2',4' dinitrophenyl hydrazine, abbreviated as PDH and N-(2-hydroxy benzylidine)-2'-hydroxy imine, abbreviated as HHP] showed significant antimicrobial activities. The rest one [N-(l-phenyl 2-hydroxy-2 phenyl ethylidine) 2'-hydroxy phenyl imine, abbreviated as PHP] showed moderate activity. All these three compounds were found to possess pronounced cytotoxic effect. These compounds can be considered as potent antimicrobial agents.

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참고문헌

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