• 한국의학물리학회지:의학물리
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• 제28권3호
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• pp.83-91
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• 2017

In this work, we investigated the recently proposed phase-contrast x-ray imaging (PCXI) technique, the so-called single grid-based PCXI, which has great simplicity and minimal requirements on the setup alignment. It allows for imaging of smaller features and variations in the examined sample than conventional attenuation-based x-ray imaging with lower x-ray dose. We performed a systematic simulation using a simulation platform developed by us to investigate the image characteristics. We also performed a preliminary PCXI experiment using an established a table-top setup to demonstrate the performance of the simulation platform. The system consists of an x-ray tube ($50kV_p$, 5 mAs), a focused-linear grid (200-lines/inch), and a flat-panel detector ($48-{\mu}m$ pixel size). According to our results, the simulated contrast of phase images was much enhanced, compared to that of the absorption images. The scattering length scale estimated for a given simulation condition was about 117 nm. It was very similar, at least qualitatively, to the experimental contrast, which demonstrates the performance of the simulation platform. We also found that the level of the phase gradient of oriented structures strongly depended on the orientation of the structure relative to that of linear grids.

• 대한의용생체공학회:의공학회지
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• 제30권2호
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• pp.179-184
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• 2009

Magnetic Resonance Electrical Impedance Tomography (MREIT) is a new bio-imaging modality providing cross-sectional conductivity images from measurements of internal magnetic flux densities produced by externally injected currents. Recent MREIT studies demonstrated successful conductivity image reconstructions of postmortem and in vivo canine brain. However, the whole head imaging was not achieved due to technical issues related with electrodes and noise in measured magnetic flux density data. In this study, we used a new carbon-hydrogel electrode with a large contact area and injected 30 mA imaging current through a canine head. Using a 3T MREIT system, we performed a postmortem canine experiment and produced high-resolution conductivity images of the entire canine head. Collecting magnetic flux density data inside the head subject to multiple injection currents, we reconstructed cross-sectional conductivity images using the harmonic $B_z$ algorithm. The conductivity images of the canine head show a good contrast not only inside the brain region including white and gray matter but also outside the brain region including the skull, temporalis muscle, mandible, lingualis proprius muscle, and masseter muscle.

• Investigative Magnetic Resonance Imaging
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• 제20권1호
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• pp.53-60
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• 2016

Purpose: To develop a technique for quantifying the $^{13}C$-metabolites by performing frequency-selective hyperpolarized $^{13}C$ magnetic resonance spectroscopy (MRS) in vitro which combines simple spectrally-selective excitation with spectrally interleaved acquisition. Methods: Numerical simulations were performed with varying noise level and $K_p$ values to compare the quantification accuracies of the proposed and the conventional methods. For in vitro experiments, a spectrally-selective excitation scheme was enabled by narrow-band radiofrequency (RF) excitation pulse implemented into a free-induction decay chemical shift imaging (FIDCSI) sequence. Experiments with LDH / NADH enzyme mixture were performed to validate the effectiveness of the proposed acquisition method. Also, a modified two-site exchange model was formulated for metabolism kinetics quantification with the proposed method. Results: From the simulation results, significant increase of the lactate peak signal to noise ratio (PSNR) was observed. Also, the quantified $K_p$ value from the dynamic curves were more accurate in the case of the proposed acquisition method compared to the conventional non-selective excitation scheme. In vitro experiment results were in good agreement with the simulation results, also displaying increased PSNR for lactate. Fitting results using the modified two-site exchange model also showed expected results in agreement with the simulations. Conclusion: A method for accurate quantification of hyperpolarized pyruvate and the downstream product focused on in vitro experiment was described. By using a narrow-band RF excitation pulse with alternating acquisition, different resonances were selectively excited with a different flip angle for increased PSNR while the hyperpolarized magnetization of the substrate can be minimally perturbed with a low flip angle. Baseline signals from neighboring resonances can be effectively suppressed to accurately quantify the metabolism kinetics.

• 한국정보통신학회논문지
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• 제11권5호
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• pp.991-996
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• 2007

최근 3차원 디스플레이 기술로서 유망한 집적 영상 기술을 이용하여 3차원 물체에 대한 컴퓨터 재생 방식이 활발히 연구되고 있다. 이 방식은 집적 영상 기술로 픽업되는 요소 영상을 가상의 핀홀 배열 모델을 이용하여 컴퓨터적으로 특정한 거리의 재생 평면에 확대 중첩함으로서 3차원 영상을 효과적으로 재생하는 방식이다. 그러나 많은 수의 요소 영상은 일반적으로 사각형의 구조를 가지기 때문에 확대 중첩될 경우에 재생 영상에서 격자 구조의 밝기 불균일 문제로 인한 해상도를 떨어뜨리는 문제가 존재하였다. 본 논문에서는 이러한 문제점을 극복하기 위해서 원형 매핑 모델에 기초한 컴퓨터 집적 영상 재생 방식을 제안한다. 제안하는 방식은 기존의 방식에서 발생하는 3차원 재생 영상에서의 불균일 문제를 극복할 수 있으며 3차원 영상의 해상도를 개선할 수 있다. 제안된 방식의 유용함을 보이기 위해서 컴퓨터적 모의 실험과 광학적 실험을 수행하고 그 결과를 보고한다.

• Journal of Acupuncture Research
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• 제15권2호
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• pp.301-310
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• 1998

Infrared thermographic imaging visualizes noninvasively various abnormal condition by detecting the skin temperature. As the imaging represents the objective condition by the changes in blood flow under the control of autonomic nervous system, it is used to diagnosis and monitor the lumboscral radiculopathy. And asymmetry is important in the diagnosis of disc herniation. The most common type of disc herniation occurs psoterolaterally. This frequently causes nerve root compression leading to a radiculopathy in the distribution of the involved nerve root, most of which also provoke the asymmetric changes in thermography. Central disc herniation, which accounts for 5% to 35% of disc herniation, is typically associated with low back pain. But radiculopathy is usually abscent unless central disc heriniaton is large enough to cause compression of the cauda equina. To evalute the diagnostic value of the thermographic imaging in the diagnosis of central disc herniation, the imaging of 15 normal subjects and 48 patients with central disc herniation documented by CT scan were analyzed. The patients had either bilateral radiculophathy or no radiculopathy. The imaging of patient group with non rediculopathy did not show any significant thermal difference to control. While bilateral radiculopathy group reveled hypothermic pattern compared twith control. Thermal difference between left and right side did not present any significance in non radiculopathy group but hypothermia in bilateral radiculopathy group. Large herniation group demonstrated hyperthemic pattern while the others showed no significant change. Cranial caudal thermal difference did not show any difference between experiment groups. These results shows that infrared thermographic imaging can be used central disc herniation with bilateral radiculopathy, while it seems to little useful on the diagnosis of non radiculopathic disc herniation.

• 지구물리와물리탐사
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• 제26권1호
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• pp.8-17
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• 2023

해양 환경에서의 기포는 바람, 파도, 선박 및 해저 가스 누출을 포함한 여러 요인에 의해 생성된다. 수중에서의 기포는 강력한 산란 신호를 생성하여 음향 신호를 측정하는데 영향을 미친다. 이러한 기포의 특성은 음파 신호의 세기를 감쇠시켜 소음 차단 목적으로 주로 이용되고 있으며, 최근에는 해저에서 대규모로 누출되는 메탄가스 탐지를 위한 연구가 진행되고 있다. 이러한 가스 누출은 기포플룸의 형태를 취하며, 기포의 물리적 특성과 분포 구조를 이해하는 것은 누출된 가스를 기후 변화와 연관성을 파악하는데 중요한 요소 중 하나이다. 본 연구에서는 탄성파 영상화 기법을 이용하여 기포플룸의 분포를 추정하고자 수조환경에서 실험을 수행하였으며, 별도로 제작된 인공기포 발생기, 자료 취득 시스템을 이용하여 기포에 의한 음향 신호를 취득하였다. 기포플룸을 영상화하기 위해 지진파 영상기법 중 역시간 구조보정을 이용하였으며, 획득한 음향 신호의 포락선 신호를 이용하여 기포 분포 패턴을 효과적으로 추정하였다. 영상화 결과의 검증을 위해 추정된 기포플룸의 분포와 광학카메라 영상을 비교하였다. 실험결과 탄성파 영상화 기법 통해 인공 기포플룸의 산란신호를 이용한 영상화가 가능함을 확인하였다.

• 제어로봇시스템학회논문지
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• 제20권8호
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• pp.842-848
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• 2014

In this paper, an improved method RMBE (Resizable Model Based target size Estimator) is presented for SDIIR (Strap Down Imaging Infrared) seekers. At the target engaging scenario, the IIR target measurement is separated by various parts. In this case, target object changing is important to accurate target intercept. Therefore, we need robust target size estimator. Our proposed method resize estimated target size with MC-1 (Markov Chain I) for accurate target size estimation. The performance of proposed method is tested at IIR target tracking of target intercept scenario. The experiment results show that the proposed RMBE has improved performance than MBE.

• 제어로봇시스템학회논문지
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• 제22권7호
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• pp.530-535
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• 2016

In this paper, the TTSE (Target size and Triangulation-based target Size Estimator) algorithm is proposed to estimate static target size in an imaging environment. The target size information is an important factor for accurate imaging target tracking. However, the imaging sensor cannot generate distance between the missile and target to calculate the target size. To overcome the problem, we propose the TTSE algorithm, which is based on target size and triangulation. The proposed method performance is tested in a target intercept scenario. The experiment results show that the proposed algorithm has better performance than the conventional algorithm (ET-TSE) for accurate CCD target size estimation.

• 제어로봇시스템학회논문지
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• 제20권1호
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• pp.29-36
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• 2014

In this paper, a novel MBE (Model Based target size Estimator) is presented for SDIIR (Strap Down Imaging Infrared) seekers. The target tracking requires the target size information for which residual range between target and missile should be provided. Unfortunately, in general, the missile with passive sensor such as IIR (Imaging Infrared), CCD (Coupled Charging Device) cannot obtain range information. To overcome the problem, the proposed method enables the SDIIR seeker to estimates target size by using target size model and track the target. The performance of proposed method is tested at IIR target tracking of target intercept scenario. The experiment results show that the proposed algorithm has the relatively good performance.

• 대한디지털의료영상학회논문지
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• 제16권2호
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• pp.25-29
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• 2014

The full-field digital mammography (FFDM), which has been known as a digital breast imaging system, carries out more outstanding performance than the screen-film mammography in overall image quality, skin & nipple, description of pectoral muscle and expression of micro-calcification. Thus, in this thesis, I perform experiments for both the enhancement of image quality and accurate estimation of the result in question, when detecting the very tiny-sized lesions in mammography. The image of digital breast X-rays is the important diagnostic tool for detecting early breast cancer and micro calcification lesion. The experiment of how much compression rate has an effect on the result of diagnosis in the case of microcalcification lesion, with JPEG2000 40:1 compression and over 50% enlargement led to obscure or definitely unacceptable diagnostic results is performed. And in another study of assessment of PSNR degree. I recognized the importance of standardized management system in mammography, where not to mention the accurate reading of the image has the most crucial role in diagnosis