• Title/Summary/Keyword: IkB

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A Study on the Determination of Minimum Local Load Shedding Considering the Regional DLC Potentials (지역별 직접부하제어 잠재량을 고려한 부하차단 확보량 결정에 관한 연구)

  • Shim, K.B.;Kim, J.H.;Hwang, S.W.;Lee, C.H.;Cho, I.S.
    • Proceedings of the KIEE Conference
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    • 2002.07a
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    • pp.407-409
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    • 2002
  • This paper proposes a process using the load shedding scenario method that determines the minimum local load shedding quantity considering the local DLC(Direct Load Control) potentials. So this method is applied to Kyung-In area and determined the load shedding of this area with comparison to its DLC potentials.

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Effects of Snake Venom Pharmacopuncture on a Mouse model of Cerebral Infarction

  • Choi, Chul-Hoon;Song, Ho-Sueb
    • Journal of Acupuncture Research
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    • v.36 no.3
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    • pp.140-146
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    • 2019
  • Background: This study investigated the effects of Vipera lebetina turanica snake venom (SV) on cerebral infarction induced by middle cerebral artery occlusion in mice. Methods: Following cerebral infarction, SV was injected intravenously or added to BV2 cell culture. Tissue injury was detected using triphenyltetrazolium chloride (TTC) staining, neurological deficit score, NO, ROS, and GSH/GSSG assays, qPCR, Western blot, and cell viability. Results: Cerebral infarction caused by middle cerebral artery occlusion as observed by TTC staining, showed SV inhibited cell death, reducing the number of brain cells injured due to infarction. SV treatment for cerebral infarction showed a significant decrease in abnormal behavior, as determined by the neurological deficit score. The oxidation and inflammation of the cells that had cerebral infarction caused by middle cerebral artery occlusion (NO assay, ROS, GSH/GSSG assay, and qPCR), showed significant protection by SV. Western blot of brain infarction cells showed the expression of iNOS, COX-2, p-IkB-${\alpha}$, P38, p-JNK, p-ERK to be lower in the SV group. In addition, the expression of IkB increased. BV2 cells were viable when treated with SV at $20{\mu}g/mL$ or less. Western blot of BV2 cells, treated with 0.625, 1.5, $2.5{\mu}g/mL$ of SV, showed a significant decrease in the expression of p-IkB-${\alpha}$, p-JNK, iNOS, and COX-2 on BV2 cells induced by LPS. Conclusion: SV showed anti-inflammatory and anti-oxidant effects against cerebral infarction and inflammation.

3rd SDM with FDPA Technique to Improve the Input Range (입력 범위를 개선한 FDPA 방식의 3차 시그마-델타 변조기)

  • Kwon, Ik-Jun;Kim, Jae-Bung;Cho, Seong-Ik
    • Journal of IKEEE
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    • v.18 no.2
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    • pp.192-197
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    • 2014
  • In this paper, $3^{rd}$ SDM with FDPA(Feedback Delay Pass Addition) technique to improve the input range is proposed. Conventional architecture with $3^{rd}$ transfer function is just made as adding a digital delay path in $2^{nd}$ SDM architecture. But the input range is very small because feedback path into the first integrator is increased. But, proposed architecture change feedback path into the first integrator to the second integrator, so input range could be improved about 9dB. The $3^{rd}$ SC SDM with only one operational amplifier was implemented using double-sampling technique. Simulation results for the proposed SDM designed in $0.18{\mu}m$ CMOS technology with power supply voltage 1.8V, signal bandwidth 20KHz and audible sampling frequency 2.8224MHz show SNR(Signal to Noise Ratio) of 83.8dB, the power consumption of $700{\mu}W$ and Dynamic Range of 82.8dB.

Efficient Synthesis of Cylindol A and the Proposed Structure of Cylindol B: The Structure of Cylindol B Still in Question

  • Chang, Jay-Hyok;Nam, Do-Hyun;Shin, Hyun-Ik
    • Bulletin of the Korean Chemical Society
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    • v.29 no.5
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    • pp.1003-1006
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    • 2008
  • Highly efficient syntheses of cylindol A (1) and the proposed structure of cylindol B (2) have been accomplished using common synthetic transformations from symmetrical starting materials 7 and 11, respectively. The latter synthesis revealed that the proposed structure of the natural cylindol B was assigned incorrectly. Isomers of 2 such as 15 and 16 were synthesized as a possible candidate of the natural cylindol B. However, their spectral data also did not match that of the natural cylindol B. Therefore, the structure of the natural cylindol B is yet to be resolved.

A Study on the Synthesis of Four-Bur Linkage Generating Automatic Path by Using B-Spline Interpolation (B-스플라인 보간법에 의한 자동 경로 생성이 가능한 4절링크의 합성에 관한 연구)

  • Kim, Jin-Su;Yang, Hyun-Ik
    • Journal of the Korean Society for Precision Engineering
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    • v.16 no.10
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    • pp.126-131
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    • 1999
  • Up until now, it is said that no satisfactory computer solutions have been found for synthesizing four-bar linkage based on the prescribed coupler link curve. In our study, an algorithm has been developed to improve the design synthesis of four-bar linkage automatically generating prescribed path by using B-spline interpolation. The suggested algorithm generates the desired coupler curve by using B-spline interpolation, and hence the generated curve approximates as closely as to the desired curve representing coupler link trajectory. Also, when comparing each generated polygon with the control polygon, rapid comparison by applying convex hull concept. finally, optimization process using ADS is incorporated into the algorithm based on the 5 precision point method to reduce the total optimization process time. As for examples, three different four-bar linkages were tested and the results showed the effectiveness of the algorithm.

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