• Clinical and Experimental Pediatrics
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• v.46 no.5
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• pp.484-489
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• 2003

Purpose : To understand morphologic and hemodynamic variations in patients with pulmonary atresia with intact ventricular septum(PA/IVS), and to decide the best treatment modalities, we measured right ventricular volume, inflow, and outflow valvular annulus size in these patients and compared them with those of normal newborns. Methods : Eight patients with PA/IVS diagnosed by echocardiography from January to December 2001 were enrolled in this study. Among the total eight patients, five were male and three were female. The mean age of patients was 6.9 days(1-34 days), and the mean body weight was 3,343 gm (2,970-4,000 gm). Ten fullterm newborn infants with sepsis or hyperbilirubinemia without heart disease were enrolled as a control group. Echocardiographic and Doppler studies using Acuson Aspen (7Mh probe) were recorded on super-VHS videotape and later on, with review mode. We measured volumes of right and left ventricles, aortic, pulmonic, mitral and tricuspid valvular annulus sizes using an installed program, and then these parameters were compared with those of the control group. Results : Mean Z-value of tricuspid valvular annulus in PA/IVS was $-3.69{\pm}2.80$(-8.4--0.45), and tricuspid/mitral valvular annulus size ratio $0.68{\pm}0.15$(0.43--0.84). The more the tricuspid/mitral valvular annulus size ratio, the more Z-value of tricuspid valvular annulus(P=0.003, r=0.885). Those patients who underwent pulmonary valvuloplasty(balloon or surgical) had a tendency toward larger volume of the right ventricle, more Z-value of pulmonic and tricuspid valvular annulus, and more tricuspid/mitral valvular annulus size ratio than those patients who underwent a shunt operation. Conclusion : Compared to a measurement of the volume of the right ventricle, measurements of tricuspid/mitral valvular annulus size ratio and Z-value of tricuspid valvular annulus may be easier and better parameters to decide the treatment method and to predict prognosis in PA/IVS patients.

• Journal of KIISE:Computer Systems and Theory
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• v.26 no.8
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• pp.975-983
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• 1999

최근 네트워크의 속도가 빨라지고 멀티미디어 데이터를 다루기 위한 기술들이 개발됨에 따라 많은 멀티미디어 응용 프로그램들이 인터넷에 등장하고 있다. 그러나 이들 응용프로그램들은 수신자에게 전송되는 영상.음성의 품질이 낮기 때문에 기대만큼 빠르게 확산되지 못하고 있다. 영상.음성의 품질이 낮은 이유는 현재 인터넷이 실시간 응용프로그램이 요구하는 만큼 빠르고 신뢰성 있게 데이터를 전송할 수 없기 때문이다. 현재 인터넷의 내부구조를 바꾸지 않고 품질을 높이기 위해 많은 연구들이 진행되고 있는데 그 중 하나는 동적으로 변화하는 인터넷의 상태에 맞게 멀티캐스트 트래픽의 전송율을 조절하는 종단간의 흐름제어이다. 본 논문은 기존의 흐름제어 기법인 IVS와 RLM의 성능을 개선시키기 위한 두 가지 흐름제어 기법을 소개한다. IVS는 송신자가 주기적으로 측정된 네트워크 상태에 따라 전송율을 일정하게 조절한다. 송신자가 하나의 데이타 스트림을 생성하는 IVS와는 달리 RLM에서는 송신자가 계층적 코딩에 의하여 생성된 여러개의 데이타 스트림을 전송하고 각 수신자는 자신의 네트워크 상태에 맞게 데이타 스트림을 선택하는 기법이다. 그러나 IVS는 송신자가 전송율을 일정하게 증가시키고, RLM은 각자의 네트워크 상태를 고려하지 않고 임의의 시간에 하나 이상의 데이타 스트림을 받기 때문에 성능을 저하시킬 수 있다. 본 논문에서는 TCP-like IVS와 Adaptive RLM이라는 두 가지 새로운 기법을 소개한다. TCP-like IVS는 송신자가 전송율을 동적으로 결정하고, Adaptive RLM은 하나 이상의 데이타 스트림을 받기 위해 적당한 시간을 선택할 수 있다. 본 논문에서는 시뮬레이션을 통해 여러 가지 네트워크 구조에서 두 가지 방식이 기존의 방식에 비하여 더욱 높은 대역폭 이용율과 10~20% 정도 적은 패킷손실율을 이룬다는 것을 보여준다.Abstract Nowadays, many multimedia applications for the Internet are introduced as the network gets faster and many techniques manipulating multimedia data are developed. These multimedia applications, however, do not spread widely and are not fast as expected at their introduction time due to the poor quality of image and voice delivered at receivers. The poor quality is mainly attributed to that the current Internet can not carry data as fast and reliably as the real-time applications require. To improve the quality without modifying the internal structure of the current Internet, many researches are conducted. One of them is an end-to-end flow control of multicast traffic adapting the sending rate to the dynamically varying Internet state. This paper proposes two flow-control techniques which can improve the performance of the two conventional techniques; IVS and RLM. IVS statically adjusts the sending rate based on the network state periodically estimated. Differently from IVS in which a sender produces one single data stream, in RLM a sender transmits several data streams generated by the layered coding scheme and each receiver selects some data streams based on its own network state. The more data streams a receiver receives, the better quality of image or voice the receiver can produce. The two techniques, however, can degrade the performance since IVS increases its sending rate statically and RLM accepts one more data stream at arbitrary time regardless of the network state respectively. We introduce two new techniques called TCP-like IVS and Adaptive RLM; TCP-like IVS can determine the sending rate dynamically and Adaptive RLM can select the right time to add one more data stream. Our simulation experiments show that two techniques can achieve better utilization and less packet loss by 10-20% over various network topologies.

• Journal of Advanced Navigation Technology
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• v.22 no.6
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• pp.566-576
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• 2018

The C-ITS requires the lane level positioning of the vehicle in the land transportation environment, and it is most effective to utilize the GNSS. In the precision positioning system based on satellite navigation, the evaluation of dynamic environment of lane level positioning performance should be accompanied and the evaluation system configuration should be preceded. In this paper, we selected performance indicators, assessment equipment, and reliability of reference equipment for evaluation of precision positioning user systems based on the GNSS. The performance evaluation system described above is applied to a real system, and the performance evaluation tool developed for the evaluation system is described. The numerical performance evaluation was carried out based on the data collected by carrying out the actual testbed driving. The performance evaluation by the actual driving trajectory and driving image comparison was performed to derive and analyse the evaluation results of the vehicle lane level positioning user system.

• Standardization Trend in Telecommunications
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• s.22
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• pp.55-58
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• 1991

• Journal of The Korean Society of Inherited Metabolic disease
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• v.6 no.1
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• pp.96-107
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• 2006

Citrin deficiency resulting from mutations of SLC25A13is associated with two major clinical phenotypes; neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) and adult-onset type 2 citrullinemia (CTLN2). In Korea, 7 cases of citrin deficiency have been diagnosed based on biochemical and molecular findings. Four NICCD cases were identified by newborn screening using MS/MS or presenting symptoms like cholestatic jaundice. They are all males, presenting with conjugated hyperbilirubinemia, elevated liver enzymes, hypoalbuminemia, mild hyperammonemia, elevated citrullin, methionine and threonine. All of them have been spontaneously recovered from hepatic manifestation by the age of 6-8 months. Mutation analysis has been performed using their genomic & cDNAs obtained from skin fibroblasts. They turned out to be compound heterozygotes carrying each of 851del4, IVS11+1G>A, and IVS13+1G>A. Three CTLN2 patients were identified. Two adult male patients presented with a sudden loss of consciousness, seizure, vomiting, hyperammonemia and citrullinemia in their twenties. They carried an IVS13+1G>A, 851del4, and IVS11+1G>A mutant alleles. The other CTLN2 patient was 52 year old female patient, manifesting lethargy, altered consciousness, irritability and hyperammonemia. Similar clinical symptoms had recurred at the delivery of first and second babies in her past medical history. She was managed by hemodialysis and survived with neurological sequellae. Also, we screened the presence of 9 common mutations in 500 Korean newborns using dried blood spot of filter papers. Only a allele carried 854del4 mutation. In conclusion, the entire picture of citrin deficiency in Korea including incidence, genotype, clinical features and natural courses, is still vague at the present time.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.14 no.2
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• pp.174-177
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• 2014

Isolated methylmalonic acidemia (MMA) is a group of autosomal recessive inborn errors of metabolism caused by impaired activity of methylmalonyl-coenzyme A mutase (MCM). Mutations in the gene encoding MCM (MUT ) is the most common cause of isolated MMA. In this report, we identify an asymptomatic 15 days old female who had elevated C3-acylcarnitine (C3) in the newborn screening. Her serum homocysteine was normal and urine methylmalonic acid was increased that suggested isolated MMA. She was maintained on a low-protein diet and carnitine supplementation. At 3 months of age, she was still asymptomatic and had normal growth. We analyzed MUT gene mutations. Two heterozygote mutations in the MUT gene were identified including c.323G>A and c.1672+2T>C (IVS8(+2)T>C. Among these, c.1672+2T>C (IVS8(+2)T>C) have not been described previously.

• ALGAE
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• v.34 no.2
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• pp.163-175
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• 2019

To compare the nutritional quality of TPG (Teleaulax / Plagioselmis / Geminigera) clade species of cryptomonads with that of RHO (Rhodomonas / Rhinomonas / Storeatula) clade species 6 Teleaulax amphioxeia (TA) and 1 Rhinomonas sp. strains were mass-cultured in newly designed 500-L photobioreactors to the end of exponential growth phase. Intraspecific variations (IVs) in terms of one standard deviation among the 6 TA strains in the compositions of the three macronutrients were 41.5 (protein), 89.8 (lipid), and 15.6% (carbohydrate) of the mean. When harvested from stationary growth phase mean compositions of essential amino acids (EAAs, 47.3%) and non-EAAs (52.7%) of the 2 TA strains, CR-MAL07 and CR-MAL08-2, were similar to those of a Chroomonas strain. The IVs between the 2 TA strains in the composition of EAAs (10.3 and 2.4) and non-EAAs (8.5 and 2.1% of the mean) were rather smaller than those of saturated fatty acids (30.3 and 26.1) and unsaturated fatty acids (UFAs, 12.0 and 12.5% of the mean) in f/2-Si and urea-based compound fertilizer (UCF) culture media, respectively. Mean compositions of eicosapentaenoic acid (EPA, 17.9%) and docosahexaenoic acid (DHA, 12.7%) of total fatty acids of the 2 TA strains were higher than those that of a Chroomonas strain. EPA and DHA compositions exhibited similar level of IVs between the 2 TA strains in f/2-Si (14.6 and 11.0) and UCF media (12.6 and 13.5% of the mean). Thus, the nutritional quality in terms of amino acids, UFAs, EPA, and DHA in a TPG clade species, T. amphioxeia was comparable to those of RHO clade species with notable IVs. Practically, biotechnological targets for TPG clade cryptomonad strains might be subspecies or clone level.

• Journal of Broadcast Engineering
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• v.24 no.7
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• pp.1266-1275
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• 2019

With increasing criminal rates and number of CCTVs, much attention has been paid to intelligent surveillance system on the horizon. Object detection and tracking algorithms have been developed to reduce false alarms and accurately help security agents immediately response to undesirable changes in video clips such as crimes and accidents. Many studies have proposed a variety of algorithms to improve accuracy of detecting and tracking objects outside tunnels. The proposed methods might not work well in a tunnel because of low illuminance significantly susceptible to tail and warning lights of driving vehicles. The detection performance has rarely been tested against the tunnel environment. This study investigated a feasibility of object detection and tracking in an actual tunnel environment by utilizing YOLOv3 and Kernelized Correlation Filter. We tested 40 actual video clips to differentiate pedestrians and motorcycles to evaluate the performance of our algorithm. The experimental results showed significant difference in detection between pedestrians and motorcycles without false positive rates. Our findings are expected to provide a stepping stone of developing efficient detection algorithms suitable for tunnel environment and encouraging other researchers to glean reliable tracking data for smarter and safer City.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.12
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• pp.5019-5022
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• 2014

Recently, mutations in the genes involved in cell cycle control, including CHEK2, are being considered as etiological factors in different kinds of cancers. The CHEK2 protein plays an important role in protecting damaged DNA from entering mitosis. In this study the potential effects of two common mutations $IVS2+1G{\rightarrow}A$ and Ile157Thr of CHEK2 gene in differentiated thyroid carcinoma (DTC) were evaluated. A total of 100 patients admitted to the Research Institute for Nuclear Medicine were diagnosed with DTC based on pathology reports of surgery samples. An additional 100 people were selected as a control group with no cancer history. PCR-HRM (high resolution melting) analysis was performed to deal with each of mutations in all case and control samples separately. During the analysis of $IVS2+1G{\rightarrow}A$ and Ile157Thr mutations of CHEK2 gene in the case and control groups, all the samples were identified as wild homozygote type. The finding suggests that $IVS2+1G{\rightarrow}A$ and Ile157Thr mutations of CHEK2 gene do not constitute a risk factor for DTC in the Iranian population. However, further studies with larger population are required to confirm the outcome.

• Journal of Power Electronics
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• v.17 no.3
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• pp.632-640
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• 2017

Input series output independent (ISOI) dc-dc converter systems are suitable for high voltage input and multiple output applications with low voltage rating switches. This paper proposes a novel control strategy consisting of one output voltage regulating (OVR) control loop and n-1 (n is the number of modules in the ISOI system) input voltage sharing (IVS) control loops. An ISOI system with the proposed control strategy can be applied to applications where the output loads of each module are the same. Under these conditions, IVS can be achieved and output voltages copying can be realized in an ISOI system. In this control strategy there is only one controller for each module and the design process of the control loops is simple. Since no central controller is needed in the system, modularity of the system is improved. The operation principle of the new control strategy is introduced and the control effect is simulated. Then the output power and voltage characteristics of an ISOI system under this new control strategy are analyzed. The stability of the proposed control strategy is explored base on a Hurwitz criterion, and the design guide line of the control strategy is given. A two module ISOI system prototype is fabricated and tested in the laboratory. Experimental results verify the effectiveness of the proposed control strategy.