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Generation of Neural Progenitor Cells from Pig Embryonic Germ Cells

  • Choi, Kwang-Hwan;Lee, Dong-Kyung;Oh, Jong-Nam;Kim, Seung-Hun;Lee, Mingyun;Jeong, Jinsol;Choe, Gyung Cheol;Lee, Chang-Kyu
    • Journal of Animal Reproduction and Biotechnology
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    • v.35 no.1
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    • pp.42-49
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    • 2020
  • As a preclinical study, many researchers have been attempted to convert the porcine PSCs into several differentiated cells with transplantation of the differentiated cells into the pigs. Here, we attempted to derive neuronal progenitor cells from pig embryonic germ cells (EGCs). As a result, neuronal progenitor cells could be derived directly from pig embryonic germ cells through the serum-free floating culture of EB-like aggregates (SFEB) method. Treating retinoic acid was more efficient for inducing neuronal lineages from EGCs rather than inhibiting SMAD signaling. The differentiated cells expressed neuronal markers such as PAX6, NESTIN, and SOX1 as determined by qRT-PCR and immunostaining. These data indicated that pig EGCs could provide valid models for human therapy. Finally, it is suggested that developing transgenic pig for disease models as well as differentiation methods will provide basic preclinical data for human regenerative medicine and lead to the success of stem cell therapy.

Measuring the Burden of Major Cancers in Korea Using Healthy Life-Year (HeaLY) (건강생활년을 이용한 우리 나라 주요 암 질환의 질병부담 측정)

  • Yoon, Seok-Jun;Kim, Chang-Yup;Shin, Young-Soo;Choi, Yong-Jun
    • Journal of Preventive Medicine and Public Health
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    • v.34 no.4
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    • pp.372-378
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    • 2001
  • Objectives : This study introduced the healthy life-year(HeaLY), a composite indicator of disease burden, and used it to estimate the burden of major cancers in Korea. Methods : We collected data from the national death certificate database, the national health insurance claims database and the abridged life table. This data was used to create a spreadsheet and estimate the burden of major cancers by sex in terms of HeaLYs. Results : The burden of 10 major cancers for males was 2,248.97 person-year in terms of HeaLYs. Stomach cancer, liver cancer, and lung cancer were responsible for 75.2% of the burden of 10 major cancers. The disease burden of 10 major cancers for females was estimated to be 1,567.58 person-years. About two thirds of HeaLYs lost were from stomach cancer, liver cancer, lung cancer, colorectal cancer, and breast cancer. The rankings among 10 major cancers were somewhat different in terms of both HeaLYs and deaths as the HeaLY method considers both mortality and morbidity. Conclusions : Despite the limitations of the data sources, we conclude that HeaLY can aid in setting policy priorities concerning major cancers by estimating the disease burden of these cancers. Time-series analysis of the disease burden using HeaLY and DALY will elucidate the strengths and weaknesses of both methods.

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The Effects of Work Value and Major Satisfaction of Dental Hygiene Students on Career Decision Self-Efficacy (치위생 전공 대학생의 직업 가치관과 전공만족도가 진로 결정 자기효능감에 미치는 영향)

  • Ji, Jae-Hoon;Heo, Seong-Eun
    • Journal of Convergence for Information Technology
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    • v.9 no.6
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    • pp.183-193
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    • 2019
  • This study aimed to investigate the effects of work value and major satisfaction of dental hygiene students on career decision self-efficacy. A survey was conducted on dental hygiene students of a university in B area, and data were analyzed by using SPSS 24.0 and AMOS 24.0 program. The extrinsic work value had a positive effect on the career decision self-efficacy directly and a negative effect on the major satisfaction, a mediator. The intrinsic work value had a positive effect on the major satisfaction directly. Additionally, extrinsic and intrinsic work values had an indirect effect on career decision self-efficacy through major satisfaction. The results suggest that it is necessary to form desirable work values and increase the level of major satisfaction in order to improve career decision self-efficacy and could be used as fundamental data for setting a career and education direction of dental hygiene students.

The Influence of Self-Management of Dance Major High School Students on Eating Attitudes and Eating Disorders (무용전공 고등학생의 자기관리가 섭식태도와 섭식장애에 미치는 영향)

  • Ku, Mi-Na;Oh, Eun-Gyeoung
    • Journal of Digital Convergence
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    • v.19 no.2
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    • pp.531-538
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    • 2021
  • The purpose of this study is to investigate the effect of self-management of dance major high school students on eating attitudes and eating disorders. The subjects of this study were 239 dance major students at art high schools located in Seoul, Gyeonggi-do and Chungcheong-do, and a questionnaire was used as a survey tool. For data analysis, multiple regression analysis and hierarchical regression analysis were performed to derive the following results. First, interpersonal management of dance major high school students affects restrained eating, and body management affects external and emotional eating. Second, self-management of dance major high school students has a significant effect on anorexia. Third, the eating attitude of dance major high school students strongly mediates self-management and eating disorders. The above results indicate that the management of excessive body of dance major high school students has a high influence on eating attitude and anorexia. Accordingly, it is considered that leaders need careful guidance on correct eating behavior of students.

A study on the relationship between attention deficit hyperactivity disorder, college adjustment, major satisfaction, and academic motivation in college students (대학생의 ADHD성향과 대학적응, 전공만족 및 학습동기의 관련성 연구)

  • Song, Kwui-Sook;Lee, Su-Jung
    • Journal of Korean society of Dental Hygiene
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    • v.21 no.3
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    • pp.311-318
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    • 2021
  • Objectives: The purpose of this study was to understand the level and patterns of college adjustment, major satisfaction, academic engagement, and attention deficit hyperactivity disorder (ADHD). This study examined the factors influencing adaptation to college life. Methods: This study was approved by the institutional review board of 00 university. We analyzed 166 survey data responses collected by distributing questionnaires from June 1 to July 2, 2020. Statistical product and service solutions version 23.0 was used for statistical analyses. The data were presented as frequencies and percentages or means and standard deviations, and pearson correlation analysis and multiple regression analysis were performed. Results: There was a significant difference in the average score of major satisfaction according to the type of college (university) and grades. For college adjustment, there was a significant difference in the average score according to major grades. Academic engagement showed a significant difference in the average score according to the college type and grade. Major satisfaction, college adjustment, and academic motivation showed significant positive correlations among the variables, whereas ADHD, major satisfaction, and college adjustment showed a significant negative correlation. Multiple regression analysis revealed that major satisfaction (p<0.001) and academic motivation (p<0.001) were factors affecting college adjustment (p<0.05). Conclusions: It is necessary to develop and apply specific and systematic adaptation programs to improve the understanding, control, and guidance methods for college students and to promote human relations, such as school life and social life.

The relation on academic achievement, major selection motivation, Work values, and Campus life adjustment of health college students (보건계열대학생의 학업성취도, 전공선택동기, 직업가치관 및 대학생활적응과의 관계)

  • Hong, Sun-yeun;Hur, Hwa-ra;Kim, Tee-sun
    • The Journal of the Convergence on Culture Technology
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    • v.7 no.1
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    • pp.518-524
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    • 2021
  • The purpose of this study was to examine the correlation between academic achievement, major selection motivation, work value, and campus life adjustment of healthcare major college students. Data was collected using a structured questionnaire for 495 healthcare major college students at a four-year university located in G city. As a result of the study, Academic achievement was determined with positive correlation by major selection motivation (r=.446, p<.001), work values (r=.255, p<.001), campus life adjustment(r=.391, p<.001), Major selection motivation was positively correlated with work value (r=.354, p<.001) and campus life adjustment (r=.220, p<.001). The work value showed a positive correlation with the campus life adjustment(r=.193, p<.001). It is necessary to develop a career education program that reinforces college students' major selection motivation and their work values, and a student guidance program that improves their adaptation to college life.

Comparison of Land Surface Temperature Algorithm Using Landsat-8 Data for South Korea

  • Choi, Sungwon;Lee, Kyeong-Sang;Seo, Minji;Seong, Noh-Hun;Jin, Donghyun;Jung, Daeseong;Sim, Suyoung;Jung, Im Gook;Han, Kyung-Soo
    • Korean Journal of Remote Sensing
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    • v.37 no.1
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    • pp.153-160
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    • 2021
  • Land Surface Temperature (LST) is the radiological surface temperature which observed by satellite. It is very important factor to estimate condition of the Earth such as Global warming and Heat island. For these reasons, many countries operate their own satellite to observe the Earth condition. South Korea has many landcovers such as forest, crop land, urban. Therefore, if we want to retrieve accurate LST, we would use high-resolution satellite data. In this study, we made LSTs with 4 LST retrieval algorithms which are used widely with Landsat-8 data which has 30 m spatial resolution. We retrieved LST using equations of Price, Becker et al. Prata, Coll et al. and they showed very similar spatial distribution. We validated 4 LSTs with Moderate resolution Imaging Spectroradiometer (MODIS) LST data to find the most suitable algorithm. As a result, every LST shows 2.160 ~ 3.387 K of RMSE. And LST by Prata algorithm show the lowest RMSE than others. With this validation result, we choose LST by Prata algorithm as the most suitable LST to South Korea.

A Study on the Major Perception of Nursing Freshmen (간호학과 신입생의 전공 인식에 관한 연구)

  • Jung Hyo Ju
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.3
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    • pp.145-151
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    • 2023
  • This study was attempted to provide basic data for the development of the nursing major curriculum and the admission strategy for attracting new students by identifying the perception of the nursing major among freshmen in the nursing department. Participants in this study were 40 freshmen who agreed to participate in the study among freshmen in the department of nursing who completed self-exploration, a required liberal arts course for freshmen opened in the first semester of 2021. Data collection was a study diary written by participants after 15 weeks of class, and the traditional content analysis method suggested by Heieh and Shannon was applied to data analysis. As a result of the study, three themes were derived: 'motivation for entering the nursing major', 'value of the nursing major', and 'obstacles to the nursing major'. Therefore, colleges and departments need to strengthen their entrance examination strategies to develop and conduct field trip programs for experiential departments linked to middle and high schools and It is necessary to solve the difficulties in taking major courses by providing subject and extracurricular programs targeting students who lack basic learning ability.

Study on the Pyrolysis Kinetics of Mixture of RDF and Carbonized Sludge with Thermogravimetric Analysis (RDF와 탄화슬러지 혼합물의 열중량 및 열동역학 특성 연구)

  • Sun, Jian Feng;Hwang, Hyeon Uk;Kim, Myung Gyun;Nzioka, Antony Mutua;Lee, Chang Soo;Kim, Young Ju
    • Journal of Environmental Science International
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    • v.25 no.2
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    • pp.281-288
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    • 2016
  • After analyzing of heating value of four kinds of RDF, the RDF-D has the highest heating value, was chosen to be mixed with carbonized sludge by different ratio. The 85%:15% ratio, which has the highest efficiency, was analyzed with thermogravimetric and pyrolysis kinetics. Applying of Kissinger method, activation energy was obtained from slope which is calculated from relation of ln(${\beta}/T^2{_m}$) and $1/T_m$. The kinetic parameters obtained from Kissinger method were 46.06 kJ/mol of RDF, 55.99 kJ/mol of carbonized sludge and 40.68 kJ/mol of mixture of RDF and carbonized sludge. The mixture of RDF and carbonized sludge has the lowest activation energy and frequency factor, during thermal decomposition reaction it has the slowest reaction rate and needs the lowest energy. Although activation energy with pyrolysis of RDF was irregularly scattered, it showed that activation energy was stabilized by co-pyrolysis of RDF and additives(Carbonized Sludge).

cdma2000 Physical Layer: An overview

  • Willenegger, Serge
    • Journal of Communications and Networks
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    • v.2 no.1
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    • pp.5-17
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    • 2000
  • cdma2000 offers several enhancement as compared to TIA/EIA-95, although it remains fully compatible with TIA/EIA-95 systems and allows for a smooth migration from one to the other-Major new capability include:1)connectivity to GSM-MAP in addition to IP and IS-41 networks; 2) new layering with new LAC and MAC architectures for improved service multiplexing and QoS management and efficient use of radio resource ;3) new bands and band widths of operation in support of various operator need and constraints, as well as desire for a smooth and progressive migration to cdma 2000; and 4) flexible channel structure in support of multiple services with various QoS and variable transmission rates at up to 1 Mbps per channel and 2 Mbps per user. Given the phenomenal success of wireless services and desire for higher rate wireless services. improved spectrum efficiency was a major design goal in the elaboration of cdma2000. Major capacity enhancing features include; 1) turbo coding for data transmission: 2)fast forward link power control :3) forward link transmit diversity; 4) support of directive antenna transmission techniques; 5) coherent reverse link structure; and 6) enhanced access channel operation. As users increasingly rely on their cell phone at work and at home for voice and data exchange, the stand-by time and operation-time are essential parameters that can influence customer's satisfaction and service utilization. Another major goal of cdma2000 was therefore to enable manufacturers to further optimize power utilization in the terminal. Major battery life enhancing features include; 1) improved reverse link performance (i.e., reduced transmit power per information bit; 2) new common channel structure and operation ;3) quick paging channel operation; 4) reverse link gated transmission ; and 5) new MAC stated for efficient and ubiquitous idle time idle time operation. this article provides additional details on those enhancements. The intent is not to duplicate the detailed cdma2000 radio access network specification, but rather to provide some background on the new features of cdma2000 and on the qualitative improvements as compared to the TIA/EIA-95 based systems. The article is focused on the physical layer structure and associated procedures. It therefore does not cover the MAC, LAC, radio resource management [1], or any other signaling protocols in any detail. We assume some familiarity with the basic CDMA concepts used in TIA/EIA-95.

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