• Journal of Korean Society of Environmental Engineers
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• v.38 no.3
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• pp.135-143
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• 2016

We investigated the effectiveness of natural zeolite (NZ) and sand (SD) as a capping material to block the release of heavy metals (Cd, Cr, Cu, and Zn) from heavily contaminated marine sediments and stabilize these heavy metals in the sediments. The efficiency of NZ and SD for blocking trace metals was evaluated in a flat flow tank attached with an impeller to generate wave. 0, 10, 30, and 50 mm depth of NZ or SD were capped on the contaminated marine sediments and the metal concentration in seawater was monitored. After completion of flow tank experiments, sequential extractions of the metals in the sediment below the capping material were performed. The difference of pH, EC, and DO concentration between uncapped and capped condition was not significant. The release of cations including Cd, Cu, and Zn were effectively blocked by NZ and SD capping but the interruption of Cr release was observed only in 50 mm depth of SD capped condition. However, the stabilization of Cr in 50 mm depth of SD capped condition was not achieved when compared to uncapped condition. NZ and SD capping were effective for stabilizing Cd, Cu, and Zn in marine sediments. It is concluded that the use of NZ with SD as a capping material is recommended for blocking Cd, Cr, Cu, and Zn release and stabilizing them in contaminated marine sediments.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.12
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• pp.511-517
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• 2016

Current oil-type potential transformers for trains are filled with insulating oil, which could have problems like explosions due to rising inner pressure during train operation. Therefore, mold and dry-type potential transformers are being developed to prevent explosions. One problem in manufacturing mold-type transformers is preventing void formation around the coiled core inside the mold during epoxy filling, which could cause an electrical spark. Micro voids can remain in the resin after filling, and macro voids can occur due to the structure shape. A transformer that is being developed has a cavity at the junction of the core and the coil for better performance, and when highly viscous epoxy flows inside the cavity channel, macro voids can form inside it. Therefore, in this study, the free-surface flow of the mold filling procedure was analyzed numerically by applying the VOF method. The results were used to understand the phenomena of void formation inside the cavity and to modify the process conditions to reduce voids.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.11
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• pp.340-347
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• 2016

Since the 1970s, manufacturing has been one of the key driving forces that has led to Korea's economic growth. However, this growth rate has been reduced significantly since the 2000s, and shows that revenues and employment are steadily decreasing. In addition, while manufacturing investment in Korea has dropped sharply, the United States, Germany, Japan, and other major countries have increased investment in manufacturing. These countries have promoted manufacturing innovation strategies that include the convergence of information and communications technologies (ICT) and manufacturing. For manufacturing innovation, it is important for time and cost savings required for product development to be achieved by changes in the production process, especially product design. Modeling and simulation (M&S) is a process that replaces physical product design, mockup making, and testing, with virtual product creation (modeling) and engineering analysis (simulation). In this paper, we analyze the economic ripple effect of supercomputing M&S using an input-output model technique based on the input-output tables published by the Bank of Korea. When we set the M&S budget (about US$16 million for the last 10 years) of the Korea Institute of Science and Technology Information (KISTI) as input coefficients, the effect on production inducement, value-added inducement, and employment inducement was analyzed to be US$24 million, US$13.4 million, and 267, respectively.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.11
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• pp.740-745
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• 2016

Cables are installed for tens of thousands of connections between various pieces of equipment to operate and control a commercial ship. The correct shortest-route data is necessary since these are complicated cable installations. Therefore, an overfill interval commonly exists in the shortest paths for cables as estimated by Dijkstra's algorithm, even if this algorithm is generally used. It is difficult for an electrical engineer to find the overfill interval in 3D cable models because the occupancy rate data exist in a data sheet unlinked to three-dimensional (3D) computer-aided design (CAD). The purpose of this study is to suggest a visualization method that displays the cable path and overfill interval in 3D CAD. This method also provides various color visualizations for different overfill ranges to easily determine the overfill interval. This method can reduce cable-installation man-hours from 7,000 to 5,600 thanks to a decreased re-installation rate, because the cable length calculation's accuracy is raised through fast and accurate reviews based on 3D cable visualization. As a result, material costs can also be reduced.

• Journal of Veterinary Clinics
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• v.33 no.4
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• pp.234-236
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• 2016

A 14 kg, 9-year-old, spayed female, Cocker Spaniel was presented to the Veterinary Medical Teaching Hospital of Seoul National University with a history of head tilt and circling. Otitis externa and media were diagnosed by computerized tomography, and total ear canal ablation was performed. In preanesthetic evaluation, systemic hypertension and second-degree atrioventricular block were observed, but there was no regurgitation through the heart valves. Systemic hypertension was managed with amlodipine (0.1 mg/kg, PO, BID) for the anesthesia. The dog was premedicated with cefazolin (22 mg/kg, IV) and midazolam (0.2 mg/kg, IV). Anesthesia was induced with alfaxalone (2 mg/kg, IV) and maintained with isoflurane and 100% oxygen following intubation. During surgery, vital signs (heart rate, respiratory rate, blood pressure, end tidal carbon dioxide partial pressure and body temperature) were maintained within normal ranges, but bradycardia was observed and corrected with glycopyrrolate (5 ug/kg IV, twice). During subcuticular suture, electrohemostasis was applied at the incision line, which was close to the trigeminal nerve. In no time at all, heart rate dramatically decreased from 110 to 60 beats per minute. No additional treatment was done because mean blood pressure was maintained above 70 mmHg. The heart rate recovered according to the decrease of end tidal isoflurane concentration and there were no complications associated with the anesthesia and surgery. Sudden bradycardia after electrical stimulation around the trigeminal nerve was considered as trigeminocardiac reflex (TCR). It is recommended to be careful of bradycardia from TCR when electrocautery is used in the craniofacial area during surgery.

• Journal of Digital Convergence
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• v.12 no.12
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• pp.485-490
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• 2014

The purpose of this Study investigated corneal power, corneal astigmatism and corneal axis according to spherical equivalent of refractive error. We measured spherical equivalent, corneal power and corneal astigmatism in 100 subjects from January 2014 to July 2014. Measured spherical equivalent of refractive error were $-3.01{\pm}3.79D$, corneal power of $43.79{\pm}1.60D$ and corneal astigmatism of $-1.17{\pm}0.79D$ respectively. Prevalence of spherical equivalent of refractive error were as follows : myopes (61%), emmetropes (22%), hyperopes(17%). Corneal astigmatism of refractive error greater than +0.75D was 63% and prevalence of corneal astigmatism were as follows : with-the-rlue astigmatism (84.13%), against-the-rule astigmatism(9.52%) respectively. Corneal power by spherical equivalent increased from hyperopia to myopia. Between spherical equivalent of refractive error and the mean corneal power was significant correlation(r=-0.25, p=0.01). A correlation were found between corneal power and spherical equivalent of refractive error in adults. They have the highest distribution of prevalence myopia among the refractive error. When the refractive error was increased, we found that corneal power was steeper. It is recognized that this can be refractive error factor and correct visual function is considered.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2000.05a
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• pp.465-469
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• 2000

This paper describes a single-chip full-custom implementation of pipelined adaptive decision-feedback equalizer (PADFE) using a 0.25-${\mu}{\textrm}{m}$ CMOS technology for wide-band wireless digital communication systems. To enhance the throughput rate of ADFE, two pipeline stage are inserted into the critical path of the ADFE by using delayed least-mean-square (DLMS) algorithm Redundant binary (RB) arithmetic is applied to all the data processing of the PADFE including filter taps and coefficient update blocks. When compared with conventional methods based on two's complement arithmetic, the proposed approach reduces arithmetic complexity, as well as results in a very simple complex-valued filter structure, thus suitable for VLSI implementation. The design parameters including pipeline stage, filter tap, coefficient and internal bit-width and equalization performance such as bit error rate (BER) and convergence speed are analyzed by algorithm-level simulation using COSSAP. The singl-chip PADFE contains about 205,000 transistors on an area of about 1.96$\times$1.35-$\textrm{mm}^2$. Simulation results show that it can safely operate with 200-MHz clock frequency at 2.5-V supply, and its estimated power dissipation is about 890-mW.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.27 no.4
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• pp.196-205
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• 2017

In recent years, the service design in the medical sector evolves through practical service research and development that can visualize both intangible and intangible service elements in an integrative way and derive innovative solutions to help customers feel the service more important value. With the improvement of personal income, interest in medical welfare and well-being is increasing day by day, and the focus of the medical sector shifts from the concept of treatment of diseases and illness to preventive medicine. In response to this trend, research and development of home health care system, which greatly reduces the time and space constraint of health checkup and health care by combining ubiquitous concept with medical welfare, are being actively conducted, and the needs for improving products and medical environment based on user-centered medical service and user needs in accordance with the Health Care 3.0 Era, it becomes necessary to develop on-site medical diagnostic products that reflect user-centered needs and needs. This study is intended to research and develop a product that sufficiently reflects the needs of users by applying suitable materials and shape for on-site diagnostic product in researching and developing Wireless X-ray Detector.

• Communications of Mathematical Education
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• v.31 no.4
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• pp.389-407
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• 2017

Many researches related to STEAM education have been actively conducted for developing elementary and secondary school students' comprehensive and logical thinking ability in relation to creativity education in Korea. Each sub factor of STEAM education requires creative thinking with the ability to be merged together to solve problems as integrated or combined forms in the fields of Science, Technology, Engineering, Arts, and Mathematics. Also, these STEAM activities and experiences should be carried out at various places outside the classroom in school. Although various educational programs to enhance mathematical creativity have been emphasized for elementary and secondary school students, recent tendency to focus on classroom learning in the school makes it difficult to develop creative thinking ability of students. This research is mainly based on the result of the project "Development and Administration of STEAM Outreach Program in 2016" supported by KOFAC(Korea Foundation for the Achievement of Science & Creativity). The purpose of this research is to develop a STEAM outreach program including students' activity books, teachers' manuals and administration manual that can maximize STEAM-related interest of students, and to provide a chance for elementary and secondary school students to experience creative thinking based on sub factors of STEAM. The STEAM competency total score and the perception of convergence education were significantly increased for all students participating this program, but some sub factors showed different result by school levels. The STEAM outreach program developed by this study is designed to emphasize STEAM education especially 'based on' mathematics in order to provide students with the opportunity to experience more interest in the field of mathematics and will be able to provide an interesting creative STEAM outreach program that utilizes a variety of activities which, we expect, would help students to consider their career in the future.

• BMB Reports
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• v.51 no.2
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• pp.92-97
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• 2018

B cell leukemia/lymphoma 3 (Bcl3) plays a pivotal role in immune homeostasis, cellular proliferation, and cell survival, as a co-activator or co-repressor of transcription of the $NF-{\kappa}B$ family. Recently, it was reported that Bcl3 positively regulates pluripotency genes, including Oct4, in mouse embryonic stem cells (mESCs). However, the role of Bcl3 in the maintenance of pluripotency and self-renewal activity is not fully established. Here, we report the dynamic regulation of the proliferation, pluripotency, and self-renewal of mESCs by Bcl3 via an influence on Nanog transcriptional activity. Bcl3 expression is predominantly observed in immature mESCs, but significantly decreased during cell differentiation by LIF depletion and in mESC-derived EBs. Importantly, the knockdown of Bcl3 resulted in the loss of self-renewal ability and decreased cell proliferation. Similarly, the ectopic expression of Bcl3 also resulted in a significant reduction of proliferation, and the self-renewal of mESCs was demonstrated by alkaline phosphatase staining and clonogenic single cell-derived colony assay. We further examined that Bcl3-mediated regulation of Nanog transcriptional activity in mESCs, which indicated that Bcl3 acts as a transcriptional repressor of Nanog expression in mESCs. In conclusion, we demonstrated that a sufficient concentration of Bcl3 in mESCs plays a critical role in the maintenance of pluripotency and the self-renewal of mESCs via the regulation of Nanog transcriptional activity.