• Title/Summary/Keyword: IT영양권

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Identification of Epidermal Growth Factor Receptor(EGF-R) and Transforming Growth $Factor-{\alpha}(TGF-{\alpha})$ in both Malignant Gastric Adenocarcinoma and Adjacent Non-malignant Gastric Mucosa (위암조직과 정상조직에서의 표피성장인자 수용체와 변환성장인자의 규명)

  • 정차권
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.23 no.2
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    • pp.340-347
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    • 1994
  • The specimens used in this study were obtained from patients with primary gastric carcinoma and adjacent non-malignant mucosa from the same patients. Using the techniques of immunocyto chemicstry and in situ hybridization, transforming growth $factor-{\alpha}(TGF-{\alpha})$ and epiderimal growth factor receptor (EGF-R) nRNAs were identified. $TGF-{\alpha}$ was observed in macrophages and dividing tumor cells but, not in normal cells. EGF-R was observed both in malignant and non-malignant gastric tissues. Although normally, $TGF-{\alpha}$ is not seen in normal gastric tissues, $TGF-{\alpha}$ was discovered in the adjacent non-malignant tissue of histolgically normal, which strongly suggest that $TGF-{\alpha}$ is involved in the differentiation of cancer cells. Immunocytochemicstry using EMB-11 antibody identified the existence of macrophages which express $TGF-{\alpha}$ and EGF-R mRNA. Protein products of EGF-R was identfified using monoclonal antibody. Cancer cells were also identified in the non-malignant normal tissues by the method of immunocytochemicstry using carcino embryonic antigen (CEA)antibody. It is considered that the activity of $TGF-{\alpha}$ increased as tumor cell prolifierates. Immunocytochemistry and in situ hybridization techniques can be used to diagnose gastric cancer along with the use of ${\alpha}-feto$ protein and CEA.

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Changes of Off-Odor Constituent and Parishin Derivatives of Fermentation of Gastrodia elata Rhizome by Lactic Acid Bacteria Strains (천마의 젖산발효에 따른 이취성분 및 Parishin 유도체의 변화)

  • Song, Young Eun;Lee, In Sok;Song, Eun Ju;Choi, Min Kyung;Han, Hyun Ah;Shin, So Hee;Choi, So Ra;Lee, Ki Kwon;Kim, Myung Kon;Park, Shin Young
    • The Korean Journal of Food And Nutrition
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    • v.30 no.5
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    • pp.973-982
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    • 2017
  • Gastrodia elata Blume often has been used for the treatment of headaches, convulsions, hypertension, and neurodegenerative diseases. The main active constituents are gastrodin, 4-hydroxybenzyl alcohol, vanillyl alcohol, 4-hydroxybenzylaldehyde and parishin A, B, C and E. Because Gastrodia elata has also unacceptable off-odor (swine barnyard-like) for food, there is a need to reduce it as well as allow for greater utilization as a functional food materials. In this study, a major off-odor producing substance of Gastrodia elata was fractionated by steam distillation and silica gel column chromatography. The substance was identified as p-cresol(4-methyl phenol) by GC-MS analysis and comparison of the retention time with that of an authentic compound in GC. The content of p-cresol in fermented Gastrodia elata was decreased. A fermented sample of Latobacillus sakei for 2 days was reduced to 54.7%, when compared with a unfermented sample. The five parishin derivatives in Gastrodia elata were identified by HPLC-MS analyses, and a comparison of HPLC retention times with those of authentic compounds. When compared with parishin derivatives of an unfermented Gastrodia elata, those of Gastrodia elata fermented by L. sakei, increased to 18.3% for 2 days. Increases of about 14.0~38.4% of the total phenolic compounds and 57.4~77.3% total flavonoids were found in fermented extracts, by 3 lactic acid bacteria strains. They were compared with $97.1{\pm}2.9{\mu}g/g$ and $40.9{\pm}2.0{\mu}g/g$ in the unfermented control, respectively. The extracts of Gastrodia elata Blume that were fermented by lactic acid bacteria had higher DPPH free radical scavenging activity and FRAP reducing power than the unfermented control.

The Beneficial Effects of Pectin on Obesity In vitro and In vivo (In vitro 및 In vivo에서 펙틴의 비만 억제 효과)

  • Kwon, Jin-Young;Ann, In-Sook;Park, Kun-Young;Cheigh, Hong-Sik;Song, Yeong-Ok
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.1
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    • pp.13-20
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    • 2005
  • The effects of pectin on obesity was studied using 3T3-L1 pre-adipocytes and rats fed 20% high fat diets. The concentration of leptin released from 3T3-L1 adipocytes in the presence of pectin was significantly decreased by 85% compared to that of the control (p<0.05), however, glycerol concentration was not changed. These data indicate that pectin seems to inhibit lipids accumulation in the adipocytes rather than enhance the lipolytic activity. Forty Sprague Dawley rats were fed 20% high fat diet for 8 weeks to induce obesity and then divided equally into four groups. Experimental groups were normal diet group (ND), high fat diet group (HFD), HDF with 10% pectin group (HFP10), and HDF with 20% pectin group (HFP20). Diet for the each group was prepared to be iso-caloric following AIN-76 guideline. After obesity was induced, rats were placed on an restricted diet for 9 weeks. The body weight of HFD increased 50% (p<0.05) compared to the ND, while it was decreased by 12% and 16% for HFP10 and HFP20, respectively (p<0.05). The relative amount of visceral fats for HFDl0 and HFD20 were decreased by 45% and 59% compared to that of HDF (130%), respectively (p<0.05). Pectin seems to have a greater effect on reducing visceral fats accumulation than weight reduction. Significantly increased level of triglyceride, total cholesterol or LDL-cholesterol in the plasma of HFD was returned to the normal or even below the normal by pectin diet, while the level of HDL-cholesterol increased. Lipid lowering effect was also observed in the liver and heart. These effects of pectin were dosedependent. In conclusion, the beneficial effect of pectin on the obesity was observed from cell culture experiment and animal study in terms of inhibiting the accumulation of lipids in the adipocytes.

Characteristics of Stormwater Runoff discharged from vinyl greenhouse growing area in farming area (농촌의 비닐하우스 재배지역에서 배출되는 강우유출수의 특성)

  • Jeon, Je Chan;Lee, Sang Hyeub;Kwon, Koo Ho;Lee, Jea Woon;Kwon, Heun Gag;Min, Kyung Sok
    • Journal of Wetlands Research
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    • v.16 no.4
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    • pp.413-422
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    • 2014
  • In national water quality policy, it changed previous regulation method that focuses on concentration of pollutants in effluent water to the way that regulates total amount of pollutants. The target of water quality in watershed of each river was set up, as the government instituted Total Maximum Daily Loads(TMDL). In order to accomplish successfully TMDL, it requires that the amount of pollutant loads discharged from point and nonpoint pollutant source should be investigated. This study, therefore, conducted the monitoring of the stormwater runoff at field region in farming area. And pollutants loads and unit loads discharged from field region results is calculated. As a result, the concentration of pollutants were calculated as follows: 10.5 BOD mg/L, 19.6 $COD_{Mn}$ mg/L, 4.5 TN mg/L and 2.4 TP mg/L. The unit load of BOD, $COD_{Mn}$, TOC, TSS, TN and TP discharged from field region, also, were determined to $31.8kg/km^2/yr$, $56.7kg/km^2/yr$, $8.5kg/km^2/yr$, $560.9kg/km^2/yr$, $8.3kg/km^2/yr$ and $5.1kg/km^2/yr$, respectively. It was identified that there were some differences of unit loads between the results obtained from this study and previous one. To calculate exact unit loads, therefore, long term monitoring should be conducted.

Crop Monitoring Technique Using Spectral Reflectance Sensor Data and Standard Growth Information (지상 고정형 작물 원격탐사 센서 자료와 표준 생육정보를 융합한 작물 모니터링 기법)

  • Kim, Hyunki;Moon, Hyun-Dong;Ryu, Jae-Hyun;Kwon, Dong-Won;Baek, Jae-Kyeong;Seo, Myung-Chul;Cho, Jaeil
    • Korean Journal of Remote Sensing
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    • v.37 no.5_1
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    • pp.1199-1206
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    • 2021
  • Accordingly, attention is also being paid to the agricultural use of remote sensing technique that non-destructively and continuously detects the growth and physiological status of crops. However, when remote sensing techniques are used for crop monitoring, it is possible to continuously monitor the abnormality of crops in real time. For this, standard growth information of crops is required and relative growth considering the cultivation environment must be identified. With the relationship between GDD (Growing Degree Days), which is the cumulative temperature related to crop growth obtained from ideal cultivation management, and the vegetation index as standard growth information, compared with the vegetation index observed with the spectralreflectance sensor(SRSNDVI & SRSPRI) in each rice paddy treated with standard cultivation management and non-fertilized, it was quantitatively identified as a time series. In the future, it is necessary to accumulate a database targeting various climatic conditions and varieties in the standard cultivation management area to establish a more reliable standard growth information.

Studies on the Artificial Rearing of the Rice Stem Borer (Chilo suppressalis (WALKER)) (이화명충의 인공사육에 관한 연구)

  • Chung K. H.;Ryu J.;Kim Y. R.;Kwon S. H.
    • Korean journal of applied entomology
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    • v.12 no.1
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    • pp.29-32
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    • 1973
  • This experiment has been carried out to establish the most effective rearing method of rice stemborer, Chilo suppressalis (Walker) on artificial diets under the aseptic condition. The results obtained were summarized as follows: 1. Semi·synthetic diet was giving better results in the weight of matured larvae (96.4mg), emerging rate$(96.7\%)$ and number of egg masses (2.6) than other diets studied. 2. Number of egg masses and hatching rate were significantly increased on the semi-synthetic diet and chemically defned diet, and it may be due to the choline chloride in the diets, 3. Rice seedling was used as a convenient food material. However, it requires more labours and causes more damages of larvae in replacement of fresh seedlings. 4. A different result in larval weight and pupation rate was observed between simplified diet no. 1 and diet added with chlorella. 5. Simplified diet resulted in low hatchability in the second generation, which may be due to the mulnutrition of the diet for adults. 6. The pupation rate was significantly decreased by infection of microorganisms on matured larvae.

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Effect of Climate on the Yield of 'Ilpum' Rice Cultivar in Gyeongbuk Province, South Korea over the Past 25 Years (경북 내륙 지역 과거 25년간 기후와 일품벼 수량 변화)

  • Shin, Jong-Hee;Han, Chae-Min;Kwon, Jung-Bae;Kim, Jong-Su;Kim, Sang-Kuk
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.65 no.4
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    • pp.264-273
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    • 2020
  • 'Ilpum', a Korean short-grain mid-late maturing rice cultivar, was developed in 1990, more than 30 years ago. Despite its age, it has been the most widely grown cultivar in the Gyeongbuk province of South Korea for more than 25 years, making it the most important rice cultivar for the people of the Gyeongbuk province. The aim of this study was to analyze the relationship between the rice yield of "Ilpum', the main rice cultivar in the Gyeongbuk province, and climate elements in the Daegu (southern plain area) and the Andong (inland mountainous area) regions in Gyeongbuk, South Korea. The rice yield over the past five years increased by about 13% and 24%, compared to that produced in the late 1990s in Daegu and the early 2000s in the Andong region, respectively. The number of panicles per hill and the grain ripening rate significantly affected rice yield in the 'Ilpum' cultivars in the Daegu region. The faster heading was a factor in the increase in 'Ilpum' rice yield in the Andong region. The air temperature has been rising and sunshine duration has been increasing from the late 1990s to present in both regions. Rice yield was evaluated to understand the effect of climate factors. The rice yields increased owing to the long sunshine duration during the grain-filling stage in both regions. In Andong, increasing the maximum temperature during the vegetative stage increased rice yield. Rising air temperature during the reproductive stage also increased rice yield. In particular, long sunshine hours throughout the whole rice growing period increased the rice yield of this cultivar in the Andong region.

Topical Application of Clonazepam to Burning Mouth Syndrome (구강 작열감 증후군에서 클로나제팜의 국소적 적용)

  • Shim, Young-Joo;Choi, Jong-Hoon;Ahn, Hyung-Joon;Kwon, Jeong-Seung
    • Journal of Oral Medicine and Pain
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    • v.34 no.4
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    • pp.429-433
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    • 2009
  • Burning mouth syndrome (BMS) is defined as burning pain in the tongue or other oral mucous membrane associated with normal sign and laboratory findings at least 4 to 6 months. There are many factors that affect this condition and the pain characters are various among the sufferers, so it is difficult to diagnose exactly and treat properly. The cause of BMS is currently unknown. The etiology is presumed to be that it is related with local, systemic and psychogenic factor. The BMS is related with local factor such as allergic reaction, oral fungal infection(candidiasis), parafunctional oral habits and systemic factors such as diabetes mellitus, hypothyroidism, nutritional deficiencies(vitamin $B_{12}$, folic acid), hyposalivation and psychogenic factor such as depression, anxiety, cancerphobia. So clinicians must be aware of these factors and can give proper treatment options to patients. The management of BMS are pharmacologic management, cognitive behavioral therapy and psychotherapy treatment. Clonazepam, gabapentin, amitriptyline, alpha-lipoic acid and capsaicin are used to manage the BMS. Among these, topical clonazepam is reported that the effect is higher than systemic medication and the complications are rare. This case report is about some cases of the effect of topical clonazepam on BMS.

A Survey on the Perception and Usage Status of Dietitians in Food Service Business for Meat Products (단체급식소 영양사의 육가공품에 대한 인식 및 이용실태 조사)

  • Yong, Eun-Zu;Choi, Youn-Sang;Lee, Keun-Taik
    • Food Science of Animal Resources
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    • v.29 no.1
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    • pp.121-131
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    • 2009
  • This study attempted to investigate the perception and usage status for meat products of dietitians in the food service business in Seoul and Gangwon province. 32.8% of dietitians decided the menu reflecting the taste of students. Most of the dietitians (89.2%) checked the manufacture date of the processed meat products when they were supplied. To address the question as to whether they could distinguish the difference among ham, pressed ham, and sausage, most of them answered; 'can distinguish a little' (47.5%) or 'can't distinguish' (36.7%). The most frequently provided processed meat products were ham (33.9%), followed by sausage (21.7%). However, it is assumed that the dietitians might have mistaken the pressed ham for the classic ham. The most common frequency of the serving processed meat product in the food services was once a month (41.6%). Most desired aspect of quality improvement for the processed meat products was answered as 'hygiene/safety' (31.5%), and followed by 'higher quality' (26%). In conclusion, the improvement of the product quality and the strengthening of public information would be prerequisites for expanding the use of processed meat products in the food services and business-to-business (B2B) market in the future.

The Concentration and Input/Output of Nitrogen and Phosphorus in Paddy Fields (논에서의 질소 및 인의 농도와 유출입)

  • Shin, Dong-Seok;Kwun, Soon-Kuk
    • Korean Journal of Environmental Agriculture
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    • v.9 no.2
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    • pp.133-141
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    • 1990
  • For the purpose of evaluating nutrient loadings into rivers and lakes from agricultural land, especially from paddy fields and also nutrient degradation in drainage channels, the Total Kjeldahl Nitrogen(TKN) and the Total Phosphorus(TP) were investigated in 29.5 ha. paddy fields in Hwa-Sung, Kyong-Ki, Korea, during the period from May 8, 1989 to Sep. 27, 1989. The results of the study can be su㎜arized as follows : 1. Annual inputs into paddy fields were 180 N-kg/ha 46 P-kg/ha. by fertilization, and 15.0 TKN-kg/ha. 10.0 TP-kg/ha. by irrigation, 8.0 TKN-kg/ha. 0.34 TP-kg/ha. by rainfall respectively. The amount of nutrient involved in surface runoff from paddies was 39.0 TKN-kg/ha. 9.2 TP-kg/ha. and in seepage 7.5 TKN-kg/ha. 2.1 TP-kg/ha. respectively 2. In WS1 stream(reach length equals 950m), nutrients decreased 0.31 TKN-mg/L/km, 0.01 TP-mg/L/km and in WS2 stream (reach length equals 750m) which are more meandering and undulating than WS1, the nutrients decreased 0.84 TKN-mg/L/km, 0.11 TP-mg/L/km. From these results, it was concluded that low stream velocity due to meandering and undulation promotes more degradation of nutrient concentrations. 3. For the purpose of decreasing nutrient loads from paddy fields, the amount of fertilizer used needs to be controlled, irrigation weirs need to be constructed in the drainage channels to delay the transportation of nutrients by decelerating the stream velocity and plants such as plantain-lily need to be cultivated in the channel to consume nutrients and therefore enlarge chances of self-purification.

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