• 한국정보통신학회논문지
• /
• 제19권5호
• /
• pp.1104-1109
• /
• 2015

디지털 콘텐츠의 급속한 발전으로 미래의 요구에 부합할 수 있는 고속의 보안 암호 알고리즘 설계는 중요하다. 본 논문에서는 기존의 수열 발생기 보다 더 높은 처리율을 갖는 자체 수축형 LM-128 합산 수열 발생기를 제안한다. 임계 클럭 조절형 LM-128의 설계하고 구현하여 더 낮은 클럭 사이클을 가져서 더 높은 키 수열 발생 속도를 증명한다. 제안된 임계 클럭 조절형 발생기는 128비트 비밀 키와 초기 벡터를 갖는 내부 상태 256비트로 구성되어진다. 128-비트의 보안 수준의 암호는 고화질 및 고품질의 디지털 콘텐츠 보안에 적합하다.

• 환경영향평가
• /
• 제22권2호
• /
• pp.125-134
• /
• 2013

Plant virus coat (CP) gene-mediated protection is one of the best known approaches to protect against virus resistant transgenic plants. Transgenic N. benthamiana plants containing the CP gene of Zucchini green mottle mosaic virus (ZGMMV) were used for the environmental risk assessment of the living modified (LM) plants with plant virus resistance. The most optimal co-infection method of both ZGMMV and CMV (Cucumber mosaic virus) on Non-LM and CP-expressing LM tobacco plants was established and co-infection of CMV and ZGMMV was confirmed by polymerase chain reaction (PCR). To address the effects of LM tobacco plants on the mutation of the virus, in-vitro transcripts of CP and Replicase (Rep) derived from CMV and/or ZGMMV were inoculated onto Non-LM or LM tobacco plants. Mutation frequency of CP and Rep from CMV and ZGMMV was examined through six serial passages in Non-LM and LM tobacco plants. Little actual frequency of mutation was estimated, probably due to the limited number of transgenic plants tested in this study. However, it does not suggest environmental safety of these CP-mediated LM plants. Further study at a larger scale is needed to evaluate the environmental risk associated with the CP-expressing LM plants.

• 한국콘텐츠학회논문지
• /
• 제12권2호
• /
• pp.339-348
• /
• 2012

급성 전골수구성 백혈병(acute promyelocytic leukemia, APL)은 치료제가 한정적이고 그 또한 다양한 부작용을 초래한다. 최근 암세포 형성 억제에 세균 추출물을 사용하는 경우가 증가하는데 이를 이용하여 기존의 약제보다 효과적이면서 부작용이 적은 치료제 개발이 필요하다. 본 연구에서는 L. monocytogenes에서 분비되는 물질(LmSup)과 세균 자체가 함유하고 있는 물질(LmE)을 추출하여 HL-60 세포에 처리한 다음 세포증식 억제 효과를 보고자 하였다. 세포 생존율 및 세포고사를 확인하여 세포를 죽음으로 유도하는 지 파악한 다음 작용기전을 규명하고자 세포주기의 변화 및 ROS 생성을 관찰하였다. 그 결과, LmSup와 LmE가 급성 전골수구성 백혈병(APL) 세포인 HL-60의 세포고사를 유도하고, sub G0/G1기 증가로 세포주기를 비정상적으로 차단함으로써 세포고사를 유도함을 확인하였다. 이때, ROS가 관여함을 관찰하였다. 이를 통해, LmSup 또는 LmE의 구체적인 항암효과 및 기전 분석을 통해 난치병인 APL의 치료 방법 및 치료제 개발에 기여하고자 한다.

• 한국통신학회논문지
• /
• 제40권11호
• /
• pp.2121-2130
• /
• 2015

본 논문에서는 단일 RF 단을 사용하여 다중 스트림을 전송할 수 있는 LM-MIMO (load-modulation multiple-input multiple-output) 시스템에 대하여 알아보고, 이 시스템에서 사용하는 부하변조 (load modulation) 방법이 고차 m-PSK (phase shift keying) 심볼이나 고차 m-QAM (quadrature amplitude modulation) 심볼을 효과적으로 생성할 수 있는지 확인한다. 그리고 부하변조를 사용하는 LM-MIMO 시스템의 성능을 평가한다. LM-MIMO 시스템은 안테나가 확장되어도 단일 RF 단만을 요구하기 때문에 저복잡도, 저전력의 시스템 구성을 할 수 있다. 시뮬레이션의 결과를 살펴보면, T 모델 (model)을 사용하는 부하변조는 고차 m-PSK 변조와 고차 m-QAM 변조를 효과적으로 지원할 수 있다. 또한 부하변조를 사용하는 LM-MIMO 시스템이 기존의 이상적인 m-PSK나 m-QAM 변조를 사용하는 MIMO 시스템과 유사한 성능을 낼 수 있음을 확인하였다. 또한 $4{\times}4$ LM-MIMO 시스템이 기존의 $4{\times}4$ MIMO 시스템과 유사한 성능을 내는 것을 확인하였다.

• 대한치과보철학회지
• /
• 제35권2호
• /
• pp.373-384
• /
• 1997

In this study, 4 types of dowel pin were used to fabricate removable dies using the Pindex system. The comparison of interabutment distances between before and after sawing were conducted in each type of dowel pin, and the horizontal discrepancies in the interabutment distance according to the abutment location and the type of dowel pin were comparatively analyzed. Abutments LM(left molar), LP(left premolar), A(anterior), RP(right premolar), and RM (right molar) were used for measurement. The interabutment distances were measured between each abutment : LM-LP, LM-A, LM-RP, and LM-RM. The slide scanned image of each model was magnified on the computer screen and the measurements were conducted using the meeting point of the cross on the occlusal surface of each abutment. The results were as follows : 1. In the comparison of interabutment distances between before and after sawing in each type of dowel pin, there was no significant difference in World dowel pin(double), Bi-pin(double), Maxcel dowel pin(single). In the World dowel pin(single) there was no significant difference between LM-LPs, but in the other measurements (LM-As, LM-RPs, and LM-RMs) there was significant difference between before and after sawing(p<0.05). 2. In comparison of horizontal discrepancies of the measurement according to the abutment location, there was significant difference between measurement LM-LP($0.27{\pm}0.19mm$) and the others : LM-A($0.46{\pm}0.20mm$), LM-RP($0.38{\pm}0.25mm$), LM-RM($0.45{\pm}0.22mm$) (p<0.05). 3. In comparison of horizontal discrepancies of the measurement according to the type of dowel, there was no significant difference between each dowel. As a result when fabricating a removable die using the previously mentioned 4 types of dowel pins, it is thought that the horizontal discrepancy increased in proportion to the interabutment span length and does not depend on the type of dowel pin.

• 한국응용과학기술학회지
• /
• 제35권4호
• /
• pp.1250-1259
• /
• 2018

여주(Momordica charantia) 열수 추출물을 젖산균(Leuconostoc mesenteroidesies)으로 발효하여 얻은 생산물의 항산화 및 항당뇨 효과를 관찰하였다. 여주 발효물(MC-LM)과 여주 추출물(MC)의 항산화 활성은 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)(ABTS) radical 소거 측정법을 사용하여 관찰하였다. MC 처리군은 radical 소거활성이 거의 나타나지 않았으나 MC-LM의 경우 $500{\mu}g/mL$ 농도에서 47%의 활성이 관찰되었으며 MC-LM의 농도가 증가함에 따라 활성이 유의하게(p<0.05) 증가하는 것을 확인 할 수 있었다. MC-LM은 MC에 비해 peroxyl radical에 의한 DNA의 산화적 손상을 더 효과적으로 억제하였으며 MC-LM의 농도가 증가함에 따라 strand breakage의 억제가 유의적으로 증가 하였다(p<0.05). 혈당량과 밀접한 관련이 있는 ${\alpha}-glucosidase$의 활성 억제정도를 측정한 결과 MC는 8 mg/mL 농도에서 ${\alpha}-glucosidase$의 활성을 30.1% 감소시켰고 같은 농도에서 MC-LM은 58.9% 감소 시켰다. 또한 alloxan에 의한 RIN-m5F 췌장세포 사멸에 발효물의 영향을 관찰한 결과 MC-LM을 농도별로 처리한 군에서 세포생존율이 유의적으로(p<0.05) 증가하였으며 $1000{\mu}g/mL$ 농도에서 MC군 보다 20% 높게 증가되었다. Alloxan에 의한 ${\beta}-cell$파괴를 유도하여 RIN-m5F cell이 분비한 인슐린의 측정결과 MC-LM을 농도별로 첨가한 모든 군에서 인슐린 분비능이 증가하는 경향을 보였으며, $1000{\mu}g/mL$ 농도에서 MC군 보다 15% 높게 증가되었다. 결론적으로 본 연구에서 관찰된 결과들을 통해 여주 발효물은 항산화 및 항당뇨 효과가 있는 것으로 확인되었다.

• 대한음성학회지:말소리
• /
• 제51호
• /
• pp.99-115
• /
• 2004

In this parer, we propose LM adaptation for broadcast news recognition. We collect information of recent articles from the internet on real time, make a recent small size LM, and then interpolate recent LM with a existing LM composed of existing large broadcast news corpus. We performed interpolation experiments to get the best type of articles from recent corpus because collected recent corpus is composed of articles which are related with test set, and which are unrelated. When we made an adapted LM using recent LM with similar articles to test set through Tf-Idf method and existing LM, we got the best result that ERR of pseudo-morpheme based recognition performance has 17.2 % improvement and the number of OOV has reduction from 70 to 27.

• 대한전기학회:학술대회논문집
• /
• 대한전기학회 2007년도 제38회 하계학술대회
• /
• pp.1011-1012
• /
• 2007

The paper is proposed maximum torque control of SynRM drive using learning mechanism-fuzzy neural network(LM-FNN) controlle. The control method is applicable over the entire speed range and considered the limits of the inverter's current and voltage rated value. For each control mode, a condition that determines the optimal d-axis current ${^{i}}_d$ for maximum torque operation is derived. The proposed control algorithm is applied to SynRM drive system controlled LM-FNN controller, the operating characteristics controlled by maximum torque control are examined in detail. Also, this paper is proposed the analysis results to verify the effectiveness of the LM-FNN controller.

• Journal of Microbiology and Biotechnology
• /
• 제27권3호
• /
• pp.598-609
• /
• 2017

Pediococcus pentosaceus ID-7 was isolated from kimchi, a Korean fermented food, and it showed high activity for lactose hydrolysis. The ${\beta}$-galactosidase of P. pentosaceus ID-7 belongs to the GH2 group, which is composed of two distinct proteins. The heterodimeric LacLM type of ${\beta}$-galactosidase found in P. pentosaceus ID-7 consists of two genes partially overlapped, lacL and lacM encoding LacL (72.2 kDa) and LacM (35.4 kDa). In this study, Escherichia coli MM294 was used for the production of LacL, LacM, and LacLM. These three types of recombinant proteins were expressed, purified, and characterized. The specific activities of LacLM and LacL were 339 and 31 U/mg, respectively. However, activity was not detected with LacM alone. The optimal pH of LacLM and LacL was pH 7.5 and pH 7.0, and the optimal temperature of LacLM and LacL was $40^{\circ}C$ and $50^{\circ}C$, respectively. The optimal temperature changes indicate that LacLM is able to achieve higher activity at a relatively lower temperature. LacLM was strongly activated by $Mg^{2+}$, $Mn^{2+}$, and $Zn^{2+}$, which was not true for LacL. Consistent with this, EDTA strongly inactivated LacLM and LacL, but the presence of reducing agents did not dramatically alter the activity. Taken together, multiple alignment of amino acid sequences and phylogenetic analysis results of LacL and LacM of P. pentosaceus ID-7 suggest the evolution of LacL into LacLM and that the use of divalent metal ions results in higher activity.

• Journal of the Korean Statistical Society
• /
• 제28권4호
• /
• pp.489-501
• /
• 1999

In this paper, we consider the panel data regression model in which the disturbances have nested error component. We derive a Lagrange Multiplier(LM) test which is jointly testing for the presence of random individual effects and nested effects under the normality assumption of the disturbances. This test extends the earlier work of Breusch and Pagan(1980) and Baltagi and Li(1991). Further, it is shown that this LM test has the same asymptotic distribution without normality assumption of the disturbances.