• Journal of Information Management
• /
• v.26 no.2
• /
• pp.1-36
• /
• 1995

The purpose of this study is to analyze fundamental six functions of DIALOG, STN, ORBIT and CDP and then investigate the similarities of the four systems in terms of the functions, and also to compare the commands of these systems with ISO 8777 which is an international standard of command language for the interactive text searching. It was found that there are few differences between the four systems and ISO 8777 in functional aspects, but few similarities in command expression aspects. In addition, it was proven that these four systems are more effective than ISO 8777 in some commands.

• Journal of Information Technology Services
• /
• v.16 no.4
• /
• pp.1-13
• /
• 2017

This study examines how specific technology from Information and Communications Technology (ICT)-which plays a critical role in increasing productivity by promoting a spread of technology across the society though the use of big data, mobile or wearable devices-impacts of the productivity of society and productivity of added values, respectively. The impact of technology was studied from the perspective of efficiency levels of input. In order to provide an analysis, we have categorized ICT into 16 specific technologies and have set the number of companies and number of employees each as an input factor while setting the respective output and the output of added values as an output factor. Afterwards, we have applied data envelopment analysis (DEA) which is a form of nonparametric frontier analysis and measured the productivity and efficiency of added values for each technology. According to the analysis results, there were 2 technologies by the CRS standards, and 3 technologies by the VRS standards that showed relative efficiency levels. We have also presented some efficiency improvement strategies for specific technologies that revealed relative inefficiency and offered a reference set and projection point. In addition, we provide an analysis on scale efficiencies (SE), diminishing returns to scale (DRS), and increasing returns to scale (IRS) of each ICT.

• Journal of the military operations research society of Korea
• /
• v.18 no.2
• /
• pp.1-22
• /
• 1992

Computer-aided logistics support system is recognized an essential system to reduce supply and maintenance cost, and to improve readiness of weapon system or operationable composite machines. According to these trends, this paper focuses on the design scheme and the computerization strategy of information management system for Integrated Logistics Support (ILS) work. Suggested system. LAMIS(Logistics support Analysis Management Information System) is a total system that composed of Logistics Support Analysis Management information system (LSAM), Configuration Management Information System (CMIS), Maintenance Management Information System (MMIS), Project Management System (PMS) and Information Retrival System(IRS) etc. Also, LAMIS is a computerized tool that improves current supply and maintenance support program, that attempts to reliable requirment analysis of logistics support elements, and that supports to use the existing technical specification of similar one when weapon system acquisition project is started newly. When LAMIS implication is completed, it can be applied to logistics support of defense or commercial site. Straightway, LAMIS will be enhanced with computer - aided design system, engineering drawing system, interactive electronic technical manual system, electronic data interchange system, and three dimensional simulation system to weapon system configuration. When that is done, LAMIS is CALS system.

• Proceedings of the KSRS Conference
• /
• 2003.11a
• /
• pp.1000-1001
• /
• 2003

Like other major cities in the world, Bangkok and some other cities in Thailand are expanding rapidly. The Office of Transports and Traffic Policy and Planning had selected three cities for a study of urban change; namely, Bangkok Metropolis and vicinity ( including Nontha buri, Samut Prakan , Prathum Thani, Samut Sakhon and Nakhon Pathom), Chiang Mai and Nakhon Nayok. The main objective of the study is to monitor urban development and urban extension as well as the change of landuse from farm land to urban area during two periods by using available satellite data. LANDSAT-5 TM and SPOT-HRV panchromatic were used for the first period and LANDSAT-7 ETM+ and IRS-lD panchromatic were used for the second period with a lapsed time of 14 years. I was found that during this period Bangkok Metropolis and vicinity extended 1,222 square kilometer; Chiang Mai 68.3 square kilometer, Nakhon Nayok 5.97 square kilometer. Most landuse categories which had been changed to urban were rice paddy and mixed orchard. Some suggestion for sound urban development based on satellite data was also included.

• Geomechanics and Engineering
• /
• v.35 no.5
• /
• pp.475-486
• /
• 2023

Ballast particles have an irregular shape and are discrete in nature. Due to the discrete nature of ballast, it exhibits complex mechanical behaviour under loading conditions. The discrete element method (DEM) can model the behaviour of discrete particles under a multitude of loading conditions. DEM is used in this paper to simulate a series of three-dimensional direct shear tests in order to investigate the shear behaviour of railway ballast and its interaction at the microscopic level. Particle flow code in three dimension (PFC3D) models the irregular shape of ballast particles as clump particles. To investigate the influence of particle size distribution (PSD), real PSD of Indian railway ballast specification IRS:GE:1:2004, China high-speed rail (HSR) and French rail specifications are generated. PFC3D built-in linear contact model is used to simulate the interaction of ballast particles under various normal stresses, shearing rate and shear box sizes. The results indicate how shear resistance and volumetric changes in ballast assembly are affected by normal stress, shearing rate, PSD and shear box size. In addition to macroscopic behaviour, DEM represents the microscopic behaviour of ballast particles in the form of particle displacement at different stages of the shearing process.

• Journal of the Korean Chemical Society
• /
• v.53 no.3
• /
• pp.233-243
• /
• 2009

We have investigated the infrared spectra for CO adsorbed on silica supported nickel(Ni-Si$O_2$), silica supported copper(Cu-Si$O_2$), silica supported nickel-copper alloys(Ni/Cu-Si$O_2$) of several compositions with varying CO pressures(0.2 $torr{\sim}$50 torr) at room temperature and on pumping to vacumn at room temperature within the frequency range of 1500 $cm^{-1}{\sim}2500\;cm^{-1}$. Four bands(2059.6 $cm^{-1},\;{\sim}$2036.5 $cm^{-1},\;{\sim}$ 1868.7 $cm^{-1},\;{\sim}$ 1697.1 $cm^{-1}$) were observed for Ni-Si$O_2$, two bands($\sim$2115.5 $cm^{-1},\;{\sim}$1743.0 $cm^{-1}$) were observed for Cu-Si$O_2$ and five bands(${\sim}2123.2\;cm^{-1}$, 2059.6 $cm^{-1},\;{\sim}$2036.4 $cm^{-1},\;{\sim}$1899.5 $cm^{-1},\;{\sim}$1697.1 $cm^{-1}$) were observed for Ni/Cu-Si$O_2$. These absorption bands correspond with those of the previous reports approximately. The bands below 1800 $cm^{-1}$ were only observed with Ni metal or Ni/Cu alloy crystal plane containing step at room temperature and the ${\sim}1697.1\;cm^{-1}$ bands observed with Ni-Si$O_2$ and Ni/Cu-Si$O_2$ may be ascribed to CO molecule adsorbed on the adsorption sites near step. The bands below 2000 $cm^{-1}$ were rarely observed with Cu metal crystal plane at room temperature and the 1743.0 $cm^{-1}$ bands may be ascribed to CO molecule adsorbed on the adsorption sites near step. The band shifts of adsorbed CO with varing Cu contents from 0 to 0.5 mole fraction at the same CO pressure or at the same pumping time to vacumn were below 21 $cm^{-1}$. and comparatively small than those with other ⅠB metal addition. It may means ligand effect of Cu d electron is small.

• Nutrition Research and Practice
• /
• v.7 no.6
• /
• pp.439-445
• /
• 2013

It has been shown that dysregulation of IGF-1 signaling is associated with tumor incidence and progression, whereas blockade of the signaling can effectively inhibit carcinogenesis. Although several mechanisms of anticancer activity of quercetin were proposed, molecular targets of quercetin have not been identified yet. Hence, we assessed the effect of quercetin on IGF-1 signaling inhibition in BK5.IGF-1 transgenic (Tg) mice, which over-expresses IGF-1 in the skin epidermis. A quercetin diet (0.02% wt/wt) for 20 weeks remarkably delayed the incidence of skin tumor by 2 weeks and reduced tumor multiplicity by 35% in a 7,12-dimethylbenz(a)anthracene (DMBA)-tetradecanoyl phorbol-13-acetate (TPA) two stage mouse skin carcinogenesis protocol. Moreover, skin hyperplasia in Tg mice was significantly inhibited by a quercetin supplementation. Further analysis of the MT1/2 skin papilloma cell line showed that a quercetin treatment dose dependently suppressed IGF-1 induced phosphorylation of the IGF-1 receptor (IGF-1R), insulin receptor substrate (IRS)-1, Akt and S6K; however, had no effect on the phosphorylation of PTEN. Additionally, the quercetin treatment inhibited IGF-1 stimulated cell proliferation in a dose dependent manner. Taken together, these data suggest that quercetin has a potent anticancer activity through the inhibition of IGF-1 signaling.

• Journal of Korean Medicine for Obesity Research
• /
• v.4 no.1
• /
• pp.139-160
• /
• 2004

The obesity is detrimental to the health of people living in affluent societies. Individual differences in energy metabolism are caused primarily by single nucleotide polymorphisms(SNPs), some of which promote the development of obesity-related type 2 diabetes mellitus. Type 2 diabetes mellitus is a common multifactorial genetic syndrome, which is determined by several different genes and environmental factors. In this review, five major conclusions are reached: (1)To be clinically significant, SNPs must be relevant, prevalent, modifiable, and measurable. (2)Differences in SNPs may have been caused by famine, ultraviolet light, alcohol, climate, agricultural revolution. livestock, lactase persistence, and westernized lifestyle. (3)Candidate obesity genes of calorie intake restriction are SIM 1, MC3R, MC4R, AGRP, CART, CCK, CNTFR, DRD2, Ghrelin, 5-HT receptor, NPY, PON and those of energy metabolism are LEP, LEPR, UCP1, UCP2, UCP3, B2AR, B3AR, PGC-1, Androgen receptor and those of fat mobilization are AGT, ACE, ADA, APM1, Apolipoproteins, PPAR, FABP, FOXC2, GCGR, $11-{\beta}HSDI$, LDLR, Hormonal sensitive lipase, Perilipin, $TNF-{\alpha}$, $TNF-{\beta}$ (4)Candidate obesity genes in the eastern are NPY, LEP, LEPR, UCP1, UCP2, UCP3, B2AR, B3AR, ACE, APM1, PPAR, and FABP. (5)Candidate obesity genes in type 2 diabetes mellitus are MC3R, MC4R, B2AR, B3AR, ADA, APM1, PPAR, FABP, FOXC2, PC1, PC2, ABCC8, CAPN10, CYP19, CYP7, ENPP1, GCK, GYS1, IGF, IL-6, Insulin receptor, IRS, and LPL. The discovery of SNPs will lead to a greater understanding of the pathogenesis of obesity and to better diagnostics, treatment, and eventually prevention.

• The Journal of the Korea Contents Association
• /
• v.13 no.1
• /
• pp.366-375
• /
• 2013

Recently, management of Newspaper developmet of the internet news, broadcasting and free newspapers escalated competition between newspaper companies and other media companies as well as competition among newapaper companies. This paper analyzes the efficiency of Korean Newapaper using DEA model. We evaluate the CCR-O, BCC-O efficiency, SE and RTS of 30 Newspaper. We also suggest the Newpaper which can be benchmarked based on analyzed information. The result shows that ten Nespaper whose values of CCR-O efficiency are 1, and Fourteen Nespaper whose values of BCC efficiency are 1. RTS indicates IRS of 1 firms, DRS of 16 firms and CRS of 13 firms. To variables on the effectiveness of newspaper publishing companies for the understanding and performance analysis.

• Korean Journal of Food Science and Technology
• /
• v.52 no.1
• /
• pp.81-88
• /
• 2020

The biological activities of Platycodon grandiflorum (PG) root extracts have been studied intensively, whereas there are limited number of studies on PG seed extract (PGSE). PGSE was prepared by ethanol extraction, and its antidiabetic effect was evaluated in mice with type 2 diabetes (C57BLKS/J-db/db). Results indicated that the administration of high-dose PGSE (600 mg/kg, wb) significantly stabilized the blood glucose levels, as evidenced by the results of the oral glucose tolerance test. Mice treated with high-dose PGSE exhibited significantly lower serum hemoglobin A1c, insulin, and leptin levels after eight weeks of feeding trial (p<0.05). High-dose PGSE administration significantly improved glucose uptake in the femoral muscle of db/db mice by activating both IRS-1/PI3K/AKT/AS160 and AMPK phosphorylation pathways. GLUT4 translocation from the cytosol to the plasma membrane increased 1.7-fold in the PGSE high-dose group. These results suggest that PGSE has potential for development as an antidiabetic agent.