• The Journal of Pediatrics of Korean Medicine
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• v.37 no.3
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• pp.121-132
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• 2023

Objectives We aimed to confirm whether Humulus japonicus Extract Powder can enhance child height growth significantly and safely compared with a placebo. Methods A total of 150 children between the 3rd and 25th percentiles in height and between the ages of 6 and 9 years will be recruited to participate in this randomized, double-blind, placebo-controlled clinical trial. The participants will be randomly assigned to the treatment or placebo group. Participants in the treatment group will take one pack per day (700 mg of Humulus japonicus Extract Powder) for 24 weeks. Participants in the placebo group will take one package of placebo per day (0 mg of Humulus japonicus Extract Powder) for 24 weeks. The primary outcome will be a change in height after 12 weeks, and the secondary outcomes will be the height after 24 weeks, growth rate, height standard deviation, growth hormone, insulin-like growth factor-1 (IGF-1), insulin-like growth factor binding protein-3 (IGFBP-3), bone alkaline phosphatase (BALP), and osteocalcin after 12 and 24 weeks. Results This protocol was approved by the Institutional Review Board (IRB) of the Korean Medicine Hospital of Busan University (IRB No. PNUKHIRB-2023-03-002). Research participants will be recruited from June 2023 to December 2023. Conclusions The results of this study provide clinical information regarding the effectiveness and safety of the Humulus japonicus Extract Powder in increasing child height.

• Journal of Industrial Convergence
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• v.21 no.3
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• pp.149-157
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• 2023

The purpose of this study was to verify the mediating effect of self-efficacy in the effect of social workers' ethical consciousness on job satisfaction. Based on the ratio of the statistical yearbook of Korean social workers in 2020, the subjects of the study conducted an online survey on 512 social workers working at social welfare facilities in Seoul. The study was conducted with IRB approval. The analysis and statistics of this study used SPSS & AMOS 25.0. Bootstrapping was used to verify the mediating effect of self-efficacy in the effect of social workers' ethical consciousness on job satisfaction. As a result of the study, the positive effect on self-efficacy and job satisfaction of social workers was verified. In addition, the positive mediating effect of self-efficacy was verified between the ethical consciousness of social workers on job satisfaction. The results of the study suggest the importance of systems and practices to support capacity building and promote self-efficacy for ethical awareness to improve job satisfaction of social workers.

• Journal of dental hygiene science
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• v.23 no.3
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• pp.193-198
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• 2023

Background: The nose is located at the center of the face, and it is possible to determine race, sex, and the like. Research using the nasal index (NI) classification method to classify the shape of the nose is currently in progress. However, domestic research is required as most research is being conducted abroad. In this study, we used a 3D program to confirm the ratio of the nose shape of Koreans. Methods: One hundred patients (50 males and 50 females) in their 20s were evaluated (IRB approval no. DKUDH IRB 2020-01-007). Cone beam computed tomography was performed using the Mimics ver.22 (Materialise Co., Leuven, Belgium) 3D program to model the patient's skull and soft tissues into three views: coronal, sagittal, and frontal. To confirm the ratio of measurement metrics, analysis was performed using the SPSS ver. 23.0 (IBM Co., Armonk, NY, USA) program. Results: Ten leptorrhine (long and narrow) type, 76 mesorrhine (moderate shape) type, and 14 platyrrhine (broad and short) type noses were observed. In addition, as a result of sex comparison, five males had the leptorrhine (long and narrow) type, 40 mesorrhine (moderate shape), and five platyrrhine (broad and short) types. For females, five patients had the leptorrhine (long and narrow) type, 36 patients had the mesorrhine (moderate shape) type, and nine patients had the platyrrhine (broad and short) type. Conclusion: This study will be helpful when performing nose-related surgeries and procedures in clinical practice and for similar studies in the future.

• Journal of Internet Computing and Services
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• v.25 no.4
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• pp.97-108
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• 2024

Ethical and technical problems are becoming serious as the industrialization of artificial intelligence robots becomes active, research on risk is insufficient. In this situation, the researcher developed 52 verified indicators that can measure the body, rights, property, and social risk of artificial intelligence robots. In order to develop measurement indicators for each type of risk of artificial intelligence robots, 11 experts were interviewed in-depth after IRB deliberation. IIn addition, 328 workers in various fields where artificial intelligence robots can be introduced were surveyed to verify their fieldwork, and statistical verification such as exploratory factor analysis, reliability analysis, correlation analysis, and multiple regression analysis was verifyed to measure validity and reliability. It is expected that the measurement indicators presented in this paper will be widely used in the development, certification, education, and policies of standardized artificial intelligence robots, and become the cornerstone of the industrialization of artificial intelligence robots that are socially sympathetic and safe.

• Journal of the Health Care and Life Science
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• v.11 no.2
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• pp.279-288
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• 2023

This study examines research trends and measurement tools related to clinical practicum satisfaction among nursing students, with the goal of offering insights for future research directions A search was conducted using combinations of the keywords 'nursing college students,' 'clinical practice satisfaction,' 'practice satisfaction,' and 'practice' from 1985 to 2022 in three domestic databases. After applying selection/exclusion criteria, a final analysis was performed on 91 studies. The papers analyzed in this study consisted of 91 quantitative studies (100%), and 75 studies(82.4%) lacked IRB approval. Furthermore, the research tools used in these studies often lacked reliability and validity verification. Additionally, a significant proportion of the variables related to clinical practice satisfaction focused on individual students, with 35 types associated with individual competency and emotional characteristics. These findings indicate the need for various efforts in nursing professional development to improve students' satisfaction with clinical practice.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.43 no.1
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• pp.43-52
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• 2017

EtOAc fractions of Magnolia obovata (M. obovata) Bark extracts were studied for the potential ingredient as a safe and effective whitening cosmetic material. The concentration of active substances honokiol was determined by HPLC. In vitro, the fractions reduced the extracellular and intracellular melanin contents in B16F10 cells in dose dependently and inhibited extracellular melanin secretion ($IC_{50}=11.05{\mu}g/mL$). The $12.5{\mu}g/mL$ treatment of maximum concentration effectively inhibited up to about 60% to the amount of extracullular melanin. Also, the $12.5{\mu}g/mL$ treatment of maximum concentration effectively inhibited up to about 59% to the amount of intracullular melanin ($IC_{50}=10.85{\mu}g/mL$). The $IC_{50}$ value of ${\alpha}-arbutin$ used as a positive control was $59.99{\mu}g/mL$. So, EtOAc fractions of M. obovata Bark extracts showed whitening effect when compared with the non-treatment group. In case of in vivo study, Cosmetic cream with EtOAc fractions of M. obovata Bark extracts was approved by Ethics committee of KDRI (IRB number: KDRI-IRB-1537). As a result in progress for skin sensitization as well as assessment of skin irritation through repeated patch test, skin allergens was identified as non sensitizing agents. Also, cosmetic cream with EtOAc fractions of M. obovata Bark extracts showed significant topical whitening effect and reliable skin safety when compared with the non-treatment group. In conclusion, EtOAc fractions of M. obovata Bark extracts may be a useful cosmetic ingredient for effective skin whitening.

• Health Policy and Management
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• v.19 no.2
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• pp.1-20
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• 2009

This paper examines some relations on national crisis management and bioethics. This study stars to discuss that chance and risk of biotechnology which is the 21st century's pioneering core technology. This study reviews the traditional method that a nation(law) copes with the new scientific technique. The study also examines some difficulties of social agreement on the problems of bioethics because of nature of the rational disagreement. Then this paper attempts to incorporate the crisis of biotechnology, especially bioethics, in the system of national crisis management. this paper reviews the contents of the domestic "Act on Bioethics and Safety" on the side of the protection and restoration of crisis management. And this paper proposes some changes to manage the crisis of bioethics better, as it were, some problems of IRB and schems for improvement of it.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.932-935
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• 2005

Three dimensional laser welding technology for light car body is studied. A robot, a seam tracking system and 4kW CW Nd:YAG laser are used for three dimensional robot laser welding system. The Laser system is used 4kW Nd:YAG laser(HL4006D) of Trumpf and the Robot system is used IRB6400R of ABB. The Seam tracking system is SMRT-20LS of ServoRobot. The welding joint of steel plate are butt and lap joint. The 3-D welding for Non-linear Tailored blank is performed after the observation experiments of bead on plate. Finally, the welding process for non-linear tailored blank and front side member is developed.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1995.10a
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• pp.1165-1168
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• 1995

This paper describes the evaluation of a robot based filament winding cell consisting of an industrial robot (ASEA IRB 6/2) and an in-house fabricated mandrel drive mechanism, both being coordinated by a personal computer. As in many manufacturing processes, tradeoffs exist between accuracy and speed. The accuracy versus speed relationships of the robotic winding cell were experimentally determined for discrete, fine and medium movement modes while traversing a segmented delivery eye path for a cylindrical mandrel in three configurations (in-line, offset and angled with respect to the axis of rotation). the results show that the robot winding cell is appropriate for very accurate winding of fibre strands if the mandrel axis is concentric with the mandrel drive axis and the discrete mode(i.e. low speed) of the robot is used.

• Clinical and Experimental Pediatrics
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• v.52 no.1
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• pp.1-5
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• 2009

Children are not small adults and there is a need to carry out specific trials that cannot be performed in adults. In general, children (minors) are unable to consent but their assent should be obtained using age appropriate information. Institutional Review Board (IRB) need paediatric expertise to balance the benefits and risks of research in children. The lack of consent has implications on the design, analysis and the choice of comparators used in the trials, which should only be performed by trained investigators with paediatric experience. Pain, fear, distress and parental separation should be prevented and minimised when unavoidable. The children requires even more careful review. Children represent a vulnerable population with developmental, physiological and psychological differences from adults, which make age- and development- related research important for their benefit. Finally, criteria for the protection of children in clinical trials therefore need to be laid down. Specific protection should be defined for research performed in children, at all stages and ages.